DNA topoisomerase I and PC4 can interact with human TFIIIC to promote both accurate termination and transcription reinitiation by RNA polymerase III

Molecular Cell

Volumn 1, Issue 5, 1998, Pages 749-757

  Wang, Zhengxin ^a   Roeder, Robert G ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED RNA POLYMERASE III; DNA TOPOISOMERASE; PCSK4 PROTEIN, HUMAN; SERINE PROTEINASE; SUBTILISIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR III; TRANSCRIPTION FACTOR TFIIIC;

ARTICLE; COENZYME; DNA FOOTPRINTING; GENETIC TRANSCRIPTION; GENETICS; HELA CELL; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; PHYSIOLOGY; PROMOTER REGION; REGULATOR GENE; SERODIAGNOSIS;

COENZYMES; DNA FOOTPRINTING; DNA TOPOISOMERASES, TYPE I; HELA CELLS; HUMANS; PRECIPITIN TESTS; PROMOTER REGIONS (GENETICS); PROPROTEIN CONVERTASES; RNA POLYMERASE III; SERINE ENDOPEPTIDASES; SUBTILISINS; TERMINATOR REGIONS (GENETICS); TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS, TFIII; TRANSCRIPTION, GENETIC;

EID: 0032037384     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80074-X     Document Type: Article

References (34)

1. Campbell, F.E., and Setzer, D.R. (1992). Transcription termination by RNA polymerase III: uncoupling of polymerase release from termination signal recognition. Mol. Cell. Biol. 12, 2260-2272.
2. Chiang, C.M., Ge, H., Wang, Z., Hoffmann, A., and Roeder, R.G. (1993). Unique TATA-binding protein-containing complexes and cofactors involved in transcription by RNA polymerase II and III. EMBO J. 12, 2749-2762.
3. Chu, W.M., Wang, Z., Roeder, R.G., and Schmid, C.W. (1997). RNA polymerase III transcription repressed by Rb through its interactions with TFIIIB and TFIIIC2. J. Biol. Chem. 272, 14755-14761.
4. Cozzarelli, N.R., Gerrard, S.P., Schlissel, M., Brown, D.D., and Bogenhagen, D.F. (1983). Purified RNA polymerase III accurately and efficiently terminates transcription of 5S RNA genes. Cell 34, 829-835.
5. Dieci, G., and Sentenac, A. (1996). Facilitated recycling pathway for RNA polymerase III. Cell 84, 245-252.
6. Egyhazi, E., and Durban, E. (1987). Microinjection of anti-topoisomerase I immunoglobulin G into nuclei of Chironomus tentans salivary gland cells leads to blockage of transcription elongation. Mol. Cell. Biol. 7, 4308-4316.
7. Ge, H., and Roeder, R.G. (1994). Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes. Cell 78, 513-523.
8. Geiduschek, E.P., and Kassavetis, G.A. (1992). RNA polymerase III transcription complex. In Transcription Regulation (Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press), pp. 247-279.
9. Garg, L.C., DiAngelo, S., and Jacob, S.T. (1987). Role of DNA topoisomerase I in the transcription of supercoiled rRNA gene. Proc. Natl. Acad. Sci. USA 84, 3185-3188.
10. Kaiser, K., Stelzer, G., and Meisterernst, M. (1995). The coactivator p15 (PC4) initiates transcriptional activation during TFIIA-TFIID-promoter complex formation. EMBO J. 14, 3520-3527.
11. Kaiser, K., and Meisterernst, M. (1996). The human general co-factors. Trends Biochem. Sci. 21, 342-345.
12. Kovelman, R., and Roeder, R.G. (1990). Sarkosyl defines three intermediate steps in transcription initiation by RNA polymerase III: application to stimulation of transcription by E1A. Genes Dev. 4, 646-658.
13. Kovelman, R., and Roeder, R.G. (1992). Purification and characterization of two forms of human transcription factor TFIIIC. J. Biol. Chem. 267, 24446-24456.
14. Kretzschmar, M., Meisterernst, M., and Roeder, R.G. (1993). Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II. Proc. Natl. Acad. Sci. USA 90, 11508-11512.
15. Kretzschmar, M., Kaiser, K., Lottspeich, F., and Meisterernst, M. (1994). A novel mediator of class II gene transcription with homology to viral immediate-early transcriptional regulators. Cell 78, 525-534.
16. Lagna, G., Kovelman, R., Sukegawa, J., and Roeder, R.G. (1994). Cloning and characterization of an evolutionarily divergent DNA-binding subunit of mammalian TFIIIC. Mol. Cell. Biol. 14, 3053-3064.
17. Lang, W.H., Morrow, B.E., Ju, Q., Warner, J.R., and Reeder, R.H. (1994). A model for transcription termination by RNA polymerase I. Cell 79, 527-534.
18. Luo, Y., Fujii, H., Gerster, T., and Roeder, R.G. (1992). A novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors. Cell 71, 231-241.
19. Madden, K.R., Steward, L., and Champoux, J.J. (1995). Preferential binding of human topoisomerase I to superhelical DNA. EMBO J. 14, 5399-5409.
20. Merino, A., Madden, K.R., Lane, W.S., Champoux, J.J., and Reinberg, D. (1993). DNA topoisomerase I is involved in both repression and activation of transcription. Nature 365, 227-232.
21. o fulfill different aspects of DNA binding to various pol III genes. Nucleic Acids Res. 25, 2440-2447.
22. Roeder, R.G. (1996). The role of general initiation factors in transcription by RNA polymerase II. Trends Biochem. Sci. 21, 327-335.
23. Shykind, B.M., Kim, J., Steward, L., Champoux, J.J., and Sharp, P.A. (1997). Topoisomerase I enhances TFIID-TFIIA complex assembly during activation of transcription. Genes Dev. 11, 397-407.
24. Sinn, E, Wang, Z., Kovelman, R., and Roeder, R.G. (1995). Cloning and characterization of a TFIIIC2 subunit (TFIIICβ) whose presence correlates with activation of RNA polymerase III-mediated transcription by adenovirus E1A expression and serum factors. Genes Dev. 9, 675-685.
25. Verrijzer, C.P., and Tjian, R. (1996). TAFs mediate transcriptional activation and promoter selectivity. Trends Biochem. Sci. 21, 338-342.
26. Wang, Z., and Roeder, R.G. (1995). Structure and function of a human transcription factor TFIIIB subunit that is evolutionarily conserved and contains both TFIIB- and high-mobility-group protein 2-related domains. Proc. Natl. Acad. Sci. USA 92, 7026-7030.
27. Wang, Z., and Roeder, R.G. (1996). TFIIIC1 acts through a down-stream region to stabilize TFIIIC2 binding to RNA polymerase III promoters. Mol. Cell. Biol. 16, 6841-6850.
28. Wang, Z., and Roeder, R.G. (1997). Three human RNA polymerase III-specific subunits form a subcomplex and participate in specific transcription initiation. Genes Dev. 11, 1315-1326.
29. Wang, Z., Luo, T., and Roeder, R.G. (1997). Identification of an autonomously initiating RNA polymerase III holoenzyme containing a novel factor that is selectively inactivated during protein synthesis inhibition. Genes Dev. 11, 2371-2382.
30. Werner, M., Chaussivert, N., Willis, I.M., and Sentenac, A. (1993). Interaction between a complex of RNA polymerase III subunits and the 70-kDa component of transcription factor IIIB. J. Biol. Chem. 268, 20721-20724.
31. White, R.J., Khoo, B.C.E., Inostroza, J.A., Reinberg, D., and Jackson, S.P. (1994). Different regulation of RNA polymerase I, II, and III by the TBP-binding repressor Dr1. Science 266, 448-450.
32. Yoshinaga, S.T., Boulanger, P.A., and Berk, A.J. (1987). Resolution of human transcription factor TFIIIC into two functional components. Proc. Natl. Acad. Sci. USA 84, 3585-3589.
33. Yoshinaga, S.T., L'Etoile, N.D., and Berk, A.J. (1989). Purification and characterization of transcription factor TFIIIC2. J. Biol. Chem. 264, 10726-10731.
34. Zhang, H., Wang, J.C., and Liu, L.F. (1988). Involvement of DNA topoisomerase I in transcription of human ribosomal RNA genes. Proc. Natl. Acad. Sci. USA 85, 1060-1064.