Synthesis and properties of dextran-5-aminosalicylic acid ester as a potential colon-specific prodrug of 5-aminosalicylic acid

Archives of Pharmacal Research

Volumn 21, Issue 2, 1998, Pages 179-186

  Jung, Yun Jin ^a   Lee, Jeoung Soo ^a   Kim, Hak Hyun ^a   Kim, Yun Taek ^a   Kim, Young Mi ^a  

^a Pusan National University   (South Korea)

Author keywords

5 Aminosalicylic acid; Colon specific delivery; Crohn's disease; Dextran 5 aminosalicylic acid ester; Inflammatory bowel disease; Ulcerative colitis

Indexed keywords

AMINOSALICYLIC ACID DERIVATIVE; BUFFER; DEXTRAN; DEXTRAN 5 AMINOSALICYLIC ACID; DEXTRAN-5-AMINOSALICYLIC ACID; MESALAZINE; PRODRUG;

ANIMAL; ARTICLE; CALIBRATION; CECUM; COLON; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; METABOLISM; RAT; SPRAGUE DAWLEY RAT; STOMACH; SYNTHESIS; ULTRAVIOLET SPECTROPHOTOMETRY;

AMINOSALICYLIC ACIDS; ANIMALS; BUFFERS; CALIBRATION; CECUM; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLON; DEXTRANS; MALE; MESALAMINE; PRODRUGS; RATS; RATS, SPRAGUE-DAWLEY; SPECTROPHOTOMETRY, ULTRAVIOLET; STOMACH;

EID: 0032034879     PISSN: 02536269     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02974025     Document Type: Article

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