The role of 11β -hydroxysteroid dehydrogenase in steroid hormone specificity

Journal of Steroid Biochemistry and Molecular Biology

Volumn 65, Issue 1-6, 1998, Pages 311-316

  Náray Fejes Tóth, Anikó ^a   Colombowala, Ilyas K ^a   Fejes Tóth, Géza ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; ALDOSTERONE; MINERALOCORTICOID RECEPTOR; HYDROXYSTEROID DEHYDROGENASE;

ANIMAL CELL; CELLULAR DISTRIBUTION; CHO CELL; CONFERENCE PAPER; DELETION MUTANT; ENDOPLASMIC RETICULUM; ENZYME ANALYSIS; HORMONE BINDING; MOLECULAR CLONING; NONHUMAN; PROTEIN EXPRESSION; RECEPTOR OCCUPANCY; RNA BINDING; ANIMAL; CELL COMPARTMENTALIZATION; ENZYMOLOGY; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; RABBIT; REVIEW; TISSUE DISTRIBUTION;

11-BETA-HYDROXYSTEROID DEHYDROGENASES; ALDOSTERONE; ANIMALS; CELL COMPARTMENTATION; CLONING, MOLECULAR; ENDOPLASMIC RETICULUM; HYDROXYSTEROID DEHYDROGENASES; RABBITS; RECEPTORS, MINERALOCORTICOID; TISSUE DISTRIBUTION;

EID: 0032034253     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(98)00009-0     Document Type: Conference Paper

References (46)

1. Funder, J. W., Aldosterone receptors., Steroid Hormone Resistance, ed. G. P. Chrousos and D. L. Loriaux. Plenum Press, New York, London. 1986, pp. 145-152.
2. Funder J. W., Pearce P. T., Smith R., Smith A. I. Mineralocorticoid action: Target tissue specificity is enzyme, not receptor, mediated. Science. 242:1988;583-585.
3. Edwards C. R., Stewart P. M., Burt D., Brett L., McIntyre M. A., Sutanto W. S., DeKloet E. R., Monder C. Localisation of 11β-hydroxysteroid dehydrogenase-tissue specific protector of the mineralocorticoid receptor. Lancet. ii:1988;986-989.
4. Monder C., Shackleton C. H. L. 11β-hydroxysteroid dehydrogenase: Fact or fancy? Steroids. 44:1984;383-417.
5. Lakshmi V., Monder C. Evidence for independent 11-oxidase and 11-reductase activities of 11β-hydroxysteroid dehydrogenase: Enzyme latency, phase transitions, and lipid requirements. Endocrinology. 116:1985;552-560.
6. Monder C. Corticosteroids, receptors, and the organ-specific functions of 11β-hydroxysteroid dehydrogenase. FASEB J. 5:1991;3047-3054.
7. Monder C. Heterogeneity of 11β-hydroxysteroid dehydrogenase in rat tissues. J. Steroid Biochem. Mol. Biol. 40:1991;533-536.
8. Náray-Fejes-Tóth A., Watlington C. O., Fejes-Toth G. 11β-Hydroxysteroid dehydrogenase activity in the renal target cells of aldosterone. Endocrinology. 129:1991;17-21.
9. Rusvai E., Naray-Fejes-Toth A. A new isoform of 11β-hydroxysteroid dehydrogenase in aldosterone target cells. J. Biol. Chem. 268:1993;10717-10720.
10. Mercer W. R., Krozowski Z. S. Localization of an 11β-hydroxysteroid dehydrogenase activity to the distal nephron. Evidence for the existence of two species of dehydrogenase in the rat kidney. Endocrinology. 130:1992;540-543.
11. Naray-Fejes-Toth A., Fejes-Toth G. 11β-hydroxysteroid dehydrogenase in renal collecting duct cells. Steroids. 59:1994;105-110.
12. Albiston A. L., Obeyesekere V. R., Smith R. E., Krozowski Z. S. Cloning and tissue distribution of the human 11β-hydroxysteroid dehydrogenase type 2 enzyme. Mol. Cell. Endocrinol. 105:1994;R11-R17.
13. Yang K., Yu M. Evidence for distinct isoforms of 11-beta-hydroxysteroid dehydrogenase in the ovine liver and kidney. J. Steroid Biochem. Mol. Biol. 49:1994;245-250.
14. Wilson R. C., Krozowski Z. S., Li K., Obeyesekere V. R., Razzaghy-Azar M., Harbison M. D., Wei J. Q., Shackleton C. H. L., Funder J. W., New M. I. A mutation in the HSD11β2 gene in a family with apparent mineralocorticoid excess. J. Clin. Endocrin. Metab. 80:1995;2263-2266.
15. Wilson R. C., Harbison M. D., Krozowski Z. S., Funder J. W., Shackleton C. H. L., Hanauske-Abel H. M., Wei J. Q., Hertecant J., Moran A., Neiberger R. E., Balfe J. W., Fattah A., Daneman D., Licholai T., New M. I. Several homozygous mutations in the gene for 11β-hydroxysteroid dehydrogenase type 2 in patients with apparent mineralocorticoid excess. J. Clin. Endocrin. Metab. 80:1995;3145-3150.
16. Mune T., Rogerson F. M., Nikkila H., Agarwal A. K., White P. C. Human hypertension caused by mutations in the kidney isoenzyme of 11β-hydroxysteroid dehydrogenase. Nature Genetics. 10:1995;394-399.
17. Monder C., Lakshmi V., Miroff Y. Kinetic studies on rat liver 11β-hydroxysteroid dehydrogenase. Biochim. Biophys. Acta. 1115:1991;23-29.
18. Stewart P. M., Murry B. A., Mason J. I. Type 2 11beta-hydroxysteroid dehydrogenase in human fetal tissues. J. Clin. Endocrinol. Metabol. 78:1994;1529-1532.
19. Fejes-Toth G., Naray-Fejes-Toth A. Differentiated transport functions in primary cultures of rabbit collecting ducts. Am. J. Physiol. 253:1987;F1302-F1307.
20. Agarwal A. K., Mune T., Monder C., White P. C. NAD-dependent isoform of 11β-hydroxysteroid dehydrogenase. J. Biol. Chem. 269:1994;25959-25962.
21. Naray-Fejes-Toth A., Fejes-Toth G. Expression cloning of the aldosterone target cell-specific 11β-hydroxysteroid dehydrogenase from rabbit collecting duct cells. Endocrinology. 136:1995;2579-2586.
22. Zhou M. Y., Gomez-Sanchez E., Cox D. L., Cosby D., Gomez-Sanchez C. E. Cloning, expression, and tissue distribution of the rat nicotinamide adenine dinucleotide-dependent 11β-hydroxysteroid dehydrogenase. Endocrinology. 136:1995;3729-3734.
23. Cole T. J. Cloning of the mouse 11beta-hydroxysteroid dehydrogenase type 2 gene: Tissue specific expression and localization in distal convoluted tubules and collecting ducts of the kidney. Endocrinology. 136:1995;4693-4696.
24. Whorwood C. B., Mason J. I., Ricketts M. L., Howie A. J., Stewart P. M. Detection of human 11beta-hydroxysteroid dehydrogenase isoforms using RT-PCR and localization of the type 2 isoform to renal collecting ducts. Mol. Cell. Endocrinol. 110:1995;R7-R12.
25. Yang K., Matthews S. G. Cellular localization of 11β-hydroxysteroid dehydrogenase 2 gene expression in the ovine adrenal gland. Mol. Cell. Endocrinol. 111:1995;R19-R23.
26. Roland B. L., Li K. X. Z., Funder J. W. Hybridization histochemical localization of 11β-hydroxysteroid dehydrogenase type 2 in rat brain. Endocrinology. 136:1995;4697-4699.
27. Roland B. L., Funder J. W. Localization of 11β-hydroxysteroid dehydrogenase type 2 in rat tissues: In situ studies. Endocrinology. 137:1996;1123-1128.
28. Brown R. W., Diaz R., Robson A. C., Kotelevtsev Y., Mullins J. J., Kaufman M. H., Seckl J. R. The ontogeny of 11β-hydroxysteroid dehydrogenase type 2 and mineralocorticoid receptor gene expression reveal intricate control of glucocorticoid action in development. Endocrinology. 137:1996;794-797.
29. Naray-Fejes-Toth A., Rusvai E., Fejes-Toth G. Mineralocorticoid receptors and 11β-hydroxysteroid dehydrogenase in renal principal and intercalated cells. Am. J. Physiol. 266:1994;F76-F80.
30. White P. C., Mune T., Agarwal A. K. 11β-hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess. Endocrine Reviews. 18:1997;135-156.
31. Krozowski Z., Maguire J. A., Stein-Oakley A. N., Dowling J., Smith R. E., Andrews R. K. Immunohistochemical localization of the 11β-hydroxysteroid dehydrogenase type II. Enzyme in human kidney and placenta. J. Clin. Endocrinol. Metab. 80:1995;2203-2209.
32. Kyossev Z., Walker P. D., Reeves W. B. Immunolocalization of NAD-dependent 11β-hydroxysteroid dehydrogenase in human kidney and colon. Kidney Intern. 49:1996;271-281.
33. Shimojo M., Ricketts M., Petrelli M. D., Moradi P., Johnson G. D., Bradwell A. R., Hewsion M., Howie A. J., Stewart P. M. Immunodetection of 11β-hydroxysteroid dehydrogenasetype 2 in human mineralocorticoid target tissues: Evidence for nuclear localization. Endocrinology. 138:1997;1305-1311.
34. Smith R. E., Li K. X. Z., Andrews R. K., Krozowski Z. Immunohistochemical and molecular characterization of the rat 11β-hydroxysteroid dehydrogenase type II enzyme. Endocrinology. 138:1997;540-547.
35. Bonvalet J. P., Doignon I., Blot-Chabaud M., Pradelles P., Farman N. Distribution of 11β-hydroxysteroid dehydrogenase along the rabbit nephron. J. Clin. Invest. 86:1990;832-837.
36. Naray-Fejes-Toth A., Fejes-Toth G. Subcellular localization of the type 2 11β-hydroxysteroid dehydrogenase: A green fluorescent protein study. J. Biol. Chem. 271:1996;15436-15442.
37. Brown R. W., Chapman K. E., Edwards C. R., Seckl J. R. Human placental 11β-hydroxysteroid dehydrogenase: Evidence for and partial purification of a distinct NAD-dependent isoform. Endocrinology. 132:1993;2614-2621.
38. Chalfie M., Tu Y., Euskirchen G., Ward W. W., Prasher D. C. Green fluorescent protein as a marker for gene expression. Science. 263:1994;802-805.
39. Wang S., Hazelrigg T. Implications for bcd mRNA localization from spatial distribution of exu protein in Drosophila oogenesis. Nature. 369:1994;400-403.
40. Inouye S., Tsuji F. I. Aequorea green fluorescence protein. Expression of the gene and fluorescence characteristics of the recombinant protein. FEBS Letters. 341:1994;277-280.
41. Krozowski Z. S., Rundle S. E., Wallace C., Castell M. J., Shen J. H., Dowlin J., Funder J. W., Smith A. I. Immunolocalization of renal mineralocorticoid receptors with an antiserum against apeptide deduced from the complementary deoxyribonucleic acid sequence. Endocrinology. 125:1989;192-198.
42. Robertson N., Schulman G., Karnik S., Alnemri E., Litwack G. Demonstration of nuclear translocation of the mineralocorticoid receptor using an anti-MR antibody and confocal laser scanning microscopy. Mol. Endocrinol. 7:1993;1226-1239.
43. Lombes M., Farman N., Oblin M. E., Baullieu E. E., Bonvalet J. P., Erlanger B. F., Gasc J. M. Immunohistochemical localization of renal mineralocorticoid receptor by using an anti-idiotypic antibody that is an internal image of aldosterone. Proc. Natl. Acad. Sci. U.S.A. 87:1990;1086-1088.
44. Ozols J. Lumenal orientation and post-translational modifications of the liver microsomal 11β-hydroxysteroid dehydrogenase. J. Biol. Chem. 270:1995;2305-2312.
45. Luzio J. P., Banting G. Eukaryotic membrane traffic: Retrieval and retention mechanisms to achieve orgnalle residence. Trends in Biochem. 18:1993;395-398.
46. Náray-Fejes-Tóth, A. and Fejes-Tóth, G. Extranuclear localization of endogenous 11β-hydroxysteroid dehydrogenase-2 in aldosterone target cells. Endocrinology, in press (1998).