메뉴 건너뛰기




Volumn 91, Issue 7, 1998, Pages 2259-2263

Erythroid Kruppel-like factor is essential for β-globin gene expression even in absence of gene competition, but is not sufficient to induce the switch from γ-globin to β-globin gene expression

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; ERYTHROID KRUPPEL LIKE FACTOR; DNA BINDING PROTEIN; ERYTHROID KRUPPEL-LIKE FACTOR; GLOBIN; KRUPPEL LIKE FACTOR; TRANSCRIPTION FACTOR;

EID: 0032034201     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v91.7.2259     Document Type: Article
Times cited : (26)

References (35)
  • 1
    • 0002398438 scopus 로고
    • Hemoglobin switching
    • Stamatoyannopoulos G, Nienhuis AW, Majerus PW, Varmus H (eds): Philadelphia, PA, Saunders
    • Stamatoyannopoulos G, Nienhuis AW: Hemoglobin switching, in Stamatoyannopoulos G, Nienhuis AW, Majerus PW, Varmus H (eds): The Molecular Basis of Blood Diseases. Philadelphia, PA, Saunders, 1994, p 107
    • (1994) The Molecular Basis of Blood Diseases , pp. 107
    • Stamatoyannopoulos, G.1    Nienhuis, A.W.2
  • 2
    • 0025309467 scopus 로고
    • Human globin locus activation region (LAR): Role in temporal control
    • Townes TM, Behringer RR: Human globin locus activation region (LAR): Role in temporal control. Trends Genet 6:219, 1990
    • (1990) Trends Genet , vol.6 , pp. 219
    • Townes, T.M.1    Behringer, R.R.2
  • 3
    • 1842414615 scopus 로고
    • What does the locus control region control?
    • Epner E, Kim CG, Groudine M: What does the locus control region control? Curr Biol 2:262, 1992
    • (1992) Curr Biol , vol.2 , pp. 262
    • Epner, E.1    Kim, C.G.2    Groudine, M.3
  • 4
    • 0027416353 scopus 로고
    • Transcriptional regulation of multigene loci: Multilevel control
    • Dillon N, Grosveld F: Transcriptional regulation of multigene loci: Multilevel control. Trends Genet 9:134, 1993
    • (1993) Trends Genet , vol.9 , pp. 134
    • Dillon, N.1    Grosveld, F.2
  • 5
    • 0024447249 scopus 로고
    • The human β-globin locus activation region alters the developmental fate of a human fetal globin gene in transgenic mice
    • Enver T, Ebens AJ, Forrester WC, Stamatoyannopoulos G: The human β-globin locus activation region alters the developmental fate of a human fetal globin gene in transgenic mice. Proc Natl Acad Sci USA 86:7033, 1989
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 7033
    • Enver, T.1    Ebens, A.J.2    Forrester, W.C.3    Stamatoyannopoulos, G.4
  • 8
    • 0025891950 scopus 로고
    • Human γ-globin genes silenced independently of other genes in the β-globin locus
    • Dillon N, Grosveld F: Human γ-globin genes silenced independently of other genes in the β-globin locus. Nature 350:252, 1991
    • (1991) Nature , vol.350 , pp. 252
    • Dillon, N.1    Grosveld, F.2
  • 11
    • 0026704374 scopus 로고
    • Inactivation of the human β-globin gene by targeted insertion into the β-globin locus control region
    • Kim CG, Epner EM, Forrester WC, Groudine M: Inactivation of the human β-globin gene by targeted insertion into the β-globin locus control region. Genes Dev 6:928, 1992
    • (1992) Genes Dev , vol.6 , pp. 928
    • Kim, C.G.1    Epner, E.M.2    Forrester, W.C.3    Groudine, M.4
  • 12
    • 0011358792 scopus 로고
    • The regulation of human β-globin gene expression: Polarity of transcriptional competition in the human β-globin locus
    • Stamatoyannopoulous G (ed): Proceedings of the 9th Conference on Hemoglobin Switching. Andover, Hants, UK, Intercept Limited
    • Dillon N, Strouboulis J, Grosveld F: The regulation of human β-globin gene expression: Polarity of transcriptional competition in the human β-globin locus, in Stamatoyannopoulous G (ed): Molecular Biology of Hemoglobin Switching, Proceedings of the 9th Conference on Hemoglobin Switching. Andover, Hants, UK, Intercept Limited, 1995, p 23
    • (1995) Molecular Biology of Hemoglobin Switching , pp. 23
    • Dillon, N.1    Strouboulis, J.2    Grosveld, F.3
  • 14
    • 0029051646 scopus 로고
    • Transcription complex stability and chromatin dynamics in vivo
    • Wijgerde M, Grosveld F, Fraser P: Transcription complex stability and chromatin dynamics in vivo. Nature 377:209, 1995
    • (1995) Nature , vol.377 , pp. 209
    • Wijgerde, M.1    Grosveld, F.2    Fraser, P.3
  • 16
    • 0027211845 scopus 로고
    • A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins
    • Miller IJ, Bieker JJ: A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins. Mol Cell Biol 13:2776, 1993
    • (1993) Mol Cell Biol , vol.13 , pp. 2776
    • Miller, I.J.1    Bieker, J.J.2
  • 17
    • 0028174097 scopus 로고
    • Analyses of β-thalassemia mutant DNA interactions with erythroid Krüppel-like factor (EKLF), an erythroid cell-specific transcription factor
    • Feng WC, Southwood CM, Bieker JJ: Analyses of β-thalassemia mutant DNA interactions with erythroid Krüppel-like factor (EKLF), an erythroid cell-specific transcription factor. J Biol Chem 269:1493, 1994
    • (1994) J Biol Chem , vol.269 , pp. 1493
    • Feng, W.C.1    Southwood, C.M.2    Bieker, J.J.3
  • 18
    • 0344258924 scopus 로고
    • Role of erythroid Krüppel-like factor (EKLF) in erythroid-specific transcription
    • Stamatoyannopoulous G (ed): Proceedings of the 9th Conference on Hemoglobin Switching. Andover, Hants, UK, Intercept Limited
    • Bieker JJ: Role of erythroid Krüppel-like factor (EKLF) in erythroid-specific transcription, in Stamatoyannopoulous G (ed): Molecular Biology of Hemoglobin Switching, Proceedings of the 9th Conference on Hemoglobin Switching. Andover, Hants, UK, Intercept Limited, 1995, p 231
    • (1995) Molecular Biology of Hemoglobin Switching , pp. 231
    • Bieker, J.J.1
  • 19
    • 0028983427 scopus 로고
    • The erythroid Krüppel-like factor transactivation domain is a critical component for cell-specific inducibility of a β-globin promoter
    • Bieker JJ, Southwood CM: The erythroid Krüppel-like factor transactivation domain is a critical component for cell-specific inducibility of a β-globin promoter. Mol Cell Biol 15:852, 1995
    • (1995) Mol Cell Biol , vol.15 , pp. 852
    • Bieker, J.J.1    Southwood, C.M.2
  • 20
    • 0028936440 scopus 로고
    • Role of erythroid Krüppel-like factor in human γ- to β-globin gene switching
    • Donze D, Townes TM, Bieker JJ: Role of erythroid Krüppel-like factor in human γ- to β-globin gene switching. J Biol Chem 270:1955, 1995
    • (1995) J Biol Chem , vol.270 , pp. 1955
    • Donze, D.1    Townes, T.M.2    Bieker, J.J.3
  • 21
    • 0029010790 scopus 로고
    • Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene
    • Nuez B, Michalovich D, Bygrave A, Ploemacher R, Grosveld F: Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene. Nature 375:316, 1995
    • (1995) Nature , vol.375 , pp. 316
    • Nuez, B.1    Michalovich, D.2    Bygrave, A.3    Ploemacher, R.4    Grosveld, F.5
  • 22
    • 0028990264 scopus 로고
    • Lethal β-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF
    • Perkins AC, Sharpe AH, Orkin SH: Lethal β-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF. Nature 375:318, 1995
    • (1995) Nature , vol.375 , pp. 318
    • Perkins, A.C.1    Sharpe, A.H.2    Orkin, S.H.3
  • 23
    • 0029861514 scopus 로고    scopus 로고
    • Silencing of human fetal globin expression is impaired in the absence of the adult β-globin gene activator protein EKLF
    • Perkins AC, Gaensler KM, Orkin SH: Silencing of human fetal globin expression is impaired in the absence of the adult β-globin gene activator protein EKLF. Proc Natl Acad Sci USA 93:12267, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12267
    • Perkins, A.C.1    Gaensler, K.M.2    Orkin, S.H.3
  • 24
    • 0028963735 scopus 로고
    • Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Krüppel family proteins Sp1 and EKLF
    • Merika M, Orkin SH: Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Krüppel family proteins Sp1 and EKLF. Mol Cell Biol 15:2437, 1995
    • (1995) Mol Cell Biol , vol.15 , pp. 2437
    • Merika, M.1    Orkin, S.H.2
  • 25
    • 0029864417 scopus 로고    scopus 로고
    • Functional interaction of GATA-1 with erythroid Krüppel-like factor and Sp1 at defined erythroid promoters
    • Gregory RC, Taxman DJ, Seshasayee D, Kensinger MH, Bieker JJ, Wojchowski DM: Functional interaction of GATA-1 with erythroid Krüppel-like factor and Sp1 at defined erythroid promoters. Blood 87:1793, 1996
    • (1996) Blood , vol.87 , pp. 1793
    • Gregory, R.C.1    Taxman, D.J.2    Seshasayee, D.3    Kensinger, M.H.4    Bieker, J.J.5    Wojchowski, D.M.6
  • 26
    • 0025292742 scopus 로고
    • The beta-globin dominant control region: Hypersensitive site 2
    • Philipsen S, Talbot D, Fraser P, Grosveld F: The beta-globin dominant control region: Hypersensitive site 2. EMBO J 9:2159, 1990
    • (1990) EMBO J , vol.9 , pp. 2159
    • Philipsen, S.1    Talbot, D.2    Fraser, P.3    Grosveld, F.4
  • 27
    • 0025365230 scopus 로고
    • Detailed analysis of the site 3 region of the human beta-globin dominant control region
    • Talbot D, Philipsen S, Fraser P, Grosveld F: Detailed analysis of the site 3 region of the human beta-globin dominant control region. EMBO J 9:2169, 1990
    • (1990) EMBO J , vol.9 , pp. 2169
    • Talbot, D.1    Philipsen, S.2    Fraser, P.3    Grosveld, F.4
  • 29
    • 0025905166 scopus 로고
    • The 5'HS2 of the globin locus control region enhances transcription through the interaction of a multimeric complex binding at two functionally distinct NF-E2 binding sites
    • Talbot D, Grosveld F: The 5'HS2 of the globin locus control region enhances transcription through the interaction of a multimeric complex binding at two functionally distinct NF-E2 binding sites. EMBO J 10:1391, 1991
    • (1991) EMBO J , vol.10 , pp. 1391
    • Talbot, D.1    Grosveld, F.2
  • 30
    • 0029658844 scopus 로고    scopus 로고
    • Erythroid Krüppel-like factor exhibits an early and sequentially localized pattern of expression during mammalian erythroid ontogeny
    • Southwood CM, Downs KM, Bieker JJ: Erythroid Krüppel-like factor exhibits an early and sequentially localized pattern of expression during mammalian erythroid ontogeny. Dev Dynamics 206:248, 1996
    • (1996) Dev Dynamics , vol.206 , pp. 248
    • Southwood, C.M.1    Downs, K.M.2    Bieker, J.J.3
  • 31
    • 0030050402 scopus 로고    scopus 로고
    • A dominant chromatin-opening activity in 5′ hypersensitive site 3 of the human β-globin locus control region
    • Ellis J, Tan-Un KC, Harper A, Michalovich D, Yannoutsos N, Philipsen S, Grosveld F: A dominant chromatin-opening activity in 5′ hypersensitive site 3 of the human β-globin locus control region. EMBO J 15:562, 1996
    • (1996) EMBO J , vol.15 , pp. 562
    • Ellis, J.1    Tan-Un, K.C.2    Harper, A.3    Michalovich, D.4    Yannoutsos, N.5    Philipsen, S.6    Grosveld, F.7
  • 32
    • 0027330974 scopus 로고
    • Activation of the β-globin promoter by the locus control region correlates with binding of a novel factor to the CAAT box in murine erythroleukemia cells but not in K562 cells
    • Delvoye NL, Destroismaisons NM, Wall LA: Activation of the β-globin promoter by the locus control region correlates with binding of a novel factor to the CAAT box in murine erythroleukemia cells but not in K562 cells. Mol Cell Biol 13:6969, 1993
    • (1993) Mol Cell Biol , vol.13 , pp. 6969
    • Delvoye, N.L.1    Destroismaisons, N.M.2    Wall, L.A.3
  • 33
    • 0024506821 scopus 로고
    • A dominant control region from the human β-globin locus conferring integration site-independent gene expression
    • Talbot D, Collis P, Antoniou M, Vidai M, Grosveld F, Greaves DR: A dominant control region from the human β-globin locus conferring integration site-independent gene expression. Nature 338: 352, 1989
    • (1989) Nature , vol.338 , pp. 352
    • Talbot, D.1    Collis, P.2    Antoniou, M.3    Vidai, M.4    Grosveld, F.5    Greaves, D.R.6
  • 34
    • 0025101148 scopus 로고
    • Definition of the minimal requirements within the human β-globin gene and the dominant control region for high level expression
    • Collis P, Antoniou M, Grosveld F: Definition of the minimal requirements within the human β-globin gene and the dominant control region for high level expression. EMBO J 9:233, 1990
    • (1990) EMBO J , vol.9 , pp. 233
    • Collis, P.1    Antoniou, M.2    Grosveld, F.3
  • 35
    • 0024536789 scopus 로고
    • The β-globin dominant control region activates homologous and heterologous promoters in a tissue-specific manner
    • Blom van Assendelft G, Hanscombe O, Grosveld F, Greaves DR: The β-globin dominant control region activates homologous and heterologous promoters in a tissue-specific manner. Cell 56:969, 1989
    • (1989) Cell , vol.56 , pp. 969
    • Van Blom Assendelft, G.1    Hanscombe, O.2    Grosveld, F.3    Greaves, D.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.