Nutritional role of the visceral yolk sac in organogenesis-stage rat embryos

Reproductive Toxicology

Volumn 12, Issue 2, 1998, Pages 193-195

  Lloyd, John B ^a   Beckman, David A ^a   Brent, Robert L ^a  

^a NEMOURS ALFRED I DUPONT HOSPITAL FOR CHILDREN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID;

ANIMAL; ANIMAL EXPERIMENT; CONFERENCE PAPER; CULTURE MEDIUM; CYTOLOGY; EMBRYO; EMBRYO CULTURE; EMBRYO DEVELOPMENT; EMBRYO GROWTH; ENDODERM; FEMALE; FETUS DEVELOPMENT; LYSOSOME; METABOLISM; NONHUMAN; ORGANOGENESIS; PHYSIOLOGY; PREGNANCY; RAT; TISSUE CULTURE; YOLK SAC;

AMINO ACIDS; ANIMALS; CULTURE TECHNIQUES; EMBRYO; EMBRYONIC AND FETAL DEVELOPMENT; ENDODERM; FEMALE; LYSOSOMES; PREGNANCY; RATS; YOLK SAC;

ANIMALIA; MAMMALIA;

EID: 0032034160     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0890-6238(97)00148-2     Document Type: Conference Paper

References (18)

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2. 2. Beck F, Lloyd JB, Griffiths A. A histochemical and biochemical study of some aspects of placental function in the rat using maternal injection of horseradish peroxidase. J Anat. 1967;101: 461-78.
3. 3. Beck F, Lloyd JB, Griffiths A. Lysosomal enzyme inhibition by trypan blue: a theory of teratogenesis. Science (Washington DC). 1967;157:1180-2.
4. 4. Lloyd JB. Lysosomes and teratogenesis: from hypothesis to dogma and back. Reprod Toxicol. 1997;11:589-94.
5. 5. Lloyd JB. Cell physiology of the rat visceral yolk sac: a study of pinocytosis and lysosome function. Teratology. 1990;41: 383-93.
6. 6. Freeman SJ, Beck F, Lloyd JB. The role of the visceral yolk sac in mediating protein utilization by rat embryos cultured in vitro. J Embryol Exp Morphol. 1981;66:223-34.
7. 7. Freeman SJ, Lloyd JB. Evidence that protein ingested by the visceral yolk sac yields amino acids for synthesis of embryonic protein. J Embryol Exp Morphol. 1983;73:307-15.
8. 125I]polyvinylpyrrolidone by rat yolk sac cultured in vitro. J Cell Biol. 1975;64:113-22.
9. 9. Williams KE, Kidston EM, Beck F, Lloyd JB. Quantitative studies of pinocytosis. II. Kinetics of protein uptake and digestion by rat yolk sac cultured in vitro. J Cell Biol. 1975;64:123-34.
10. 10. Beckman DA, Pugarelli JE, Koszalka TR, Brent RL, Lloyd JB. Sources for amino acids for protein synthesis during early organogenesis in the rat. 2. Exchange with amino acid and protein pools in embryo and yolk sac. Placenta. 1991;12:37-46.
11. 11. Freeman SJ, Lloyd JB. Inhibition of proteolysis in rat yolk sac as a cause of teratogenesis. Effects of leupeptin in vitro and in vivo. J Embryol Exp Morphol. 1983;78:183-93.
12. 12. Beckman, DA, Lloyd JB, Brent RL. Quantitative studies on the mechanisms of amino acid supply to rat embryos during organogenesis. Reprod Toxicol. 1998;12:197-200.
13. 125I-labelled rat transferrin by early organogenesis rat conceptuses in vitro. Placenta 1997;18:553-62.
14. 12 uptake of the rat yolk sac. Dev Biol. 1966;13:311-48.
15. 12 homeostasis. Proc Natl Acad Sci USA. 1996;93:8612-7.
16. 16. Freeman SJ, Brent RL, Lloyd JB. The effect of teratogenic antiserum on yolk-sac function in rat embryos cultured in vitro. J Embryol Exp Morphol. 1982;71:63-74.
17. 17. Freeman SJ, Lloyd JB. Evidence that suramin and aurothiomalate are teratogenic in rat by disturbing yolk sac-mediated embryonic protein nutrition. Chem Biol Interact. 1986;58:49-60.
18. 18. Beckman DA, Pugurelli JE, Jensen M, Koszalka TR, Brent RL, Lloyd JB. Sources of amino acids for protein synthesis during early organogenesis in the rat. I. Relative contributions of free amino acids and of proteins. Placenta. 11:109-21.