Treatment of cytomegalovirus esophagitis in patients with acquired immune deficiency syndrome: A randomized controlled study of foscarnet Versus ganciclovir

American Journal of Gastroenterology

Volumn 93, Issue 3, 1998, Pages 317-322

  Parente, F ^a   Porro, G Bianchi ^a   Moroni, M ^a   D'Arminio, A ^a   Antinori, S ^a   Milazzo, F ^a   Coen, M ^a   Cargnel, A ^a   Fasan, A ^a   Costanzi, G ^a   Vago, L ^a   Cestari, R ^a   Missale, F ^a   Carosi, G P ^a   Castelli, F ^a   Villanacci, V ^a   Grogolato, P ^a   Viale, P ^a   Alberici, F ^a   Carniato, S ^a   Cadrobbi, P ^a   Crivellaro, P ^a   Cecchetto, A ^a   Bodini, P ^a   Carnevale, G ^a   Betri, E ^a   Rocca, F ^a   Suter, F ^a   Ravetto, F ^a   Malaguti, E ^a   Gritti, F ^a   Casadei, G P ^a   Girola, M ^a   Gavazzeni, G ^a   Parma, A ^a   Caprini, A ^a   Scalzini, F ^a   Bellomi, A ^a   Tittobello, A ^a   Fanti, L ^a   Lazzarin, A ^a   Gianotti, N ^a   Cantaboni, A ^a   Cardelli, A ^a   Ciammarughi, R ^a   Quercia, G ^a   Fiocca, R ^a   Gerna, G ^a   Saresini, A ^a   Coppola, R ^a   Ortona, L ^a   Antinori, P ^a   Vecchio, P ^a   Carazzina, G ^a   Trespi, G ^a   more..

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; FOSCARNET; GANCICLOVIR;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; BONE MARROW TOXICITY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; DRUG EFFICACY; DRUG INDUCED DISEASE; DRUG SAFETY; ESOPHAGITIS; HUMAN; HYPERPHOSPHATEMIA; HYPOCALCEMIA; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MULTICENTER STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SKIN TOXICITY; TREATMENT OUTCOME; VIRUS INFECTION;

AIDS-RELATED OPPORTUNISTIC INFECTIONS; BIOPSY; CYTOMEGALOVIRUS INFECTIONS; ESOPHAGITIS; FOSCARNET; GANCICLOVIR; HUMANS; PROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 0032033977     PISSN: 00029270     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1572-0241.1998.00317.x     Document Type: Article

References (23)

1. 1. Goodgame R. Gastrointestinal cytomegalovirus disease. Ann Intern Med 1993;119:924-35.
2. 2. Katlama C. Cytomegalovirus gastrointestinal disease in acquired immune deficiency syndrome. Eur J Gastroenterol Hepatol 1992;6:443-8.
3. 3. Bonacini M, Young T, Laine L. The causes of esophageal symptoms in human immunodeficiency virus infection: A prospective study of 110 patients. Arch Intern Med 1991;151:1567-72.
4. 4. Parente F, Cernuschi M, Rizzardini G, et al. Opportunistic infections of the esophagus not responding to oral systemic antifungals in patients with AIDS: Their frequency and treatment. Am J Gastroenterol 1991; 86:1729-34.
5. 5. Connolly G, Hawkins D, Harcourt-Webster J, et al. Oesophageal symptoms, their causes, treatment and prognosis in patients with the acquired immunodeficiency syndrome. Gut 1989;30:1033-9.
6. 6. Wilcox C. Esophageal disease in the acquired immunodeficiency syndrome: Etiology, diagnosis, and management. Am J Med 1992;92: 412-21.
7. 7. Bonacini M, Laine L. Detection of cytomegalovirus in the gastrointestinal tract: Seeking a gold standard. Am J Gastroenterol 1993;88: 332-3.
8. 8. Studies of ocular complications of AIDS Research Group in collaboration with the AIDS Clinical Trials Group: Mortality in patients with the acquired immunodeficiency syndrome treated with either foscarnet or ganciclovir for cytomegalovirus retinitis. N Engl J Med 1992;326: 213-7.
9. 9. Harb G, Bacchetti P, Jacobson G. Survival of patients with AIDS and cytomegalovirus disease treated with ganciclovir or foscarnet. AIDS 1991;5:959-65.
10. 10. Blanshard C, Benhamou Y, Dohin E, et al. Treatment of AIDS-associated gastrointestinal cytomegalovirus infection with foscarnet and ganciclovir: A randomized comparison. J Invest Dermatol 1995; 172:622-8.
11. 11. Kodsi B, Wicremesinghe P, Kozinn P, et al. Candida esophagitis: A prospective study of 27 cases. Gastroenterology 1976;71:715-9.
12. 12. Bianchi Porro G, Parente F, Cemuschi M. The diagnosis of esophageal candidiasis in patients with the acquired immune deficiency syndrome: Is endoscopy always necessary? Am J Gastroenterol 1989;84:143-6.
13. 13. Francis N, Boylston A, Roberts A, et al. Cytomegalovirus in the gastrointestinal tract of patients infected with HIV or AIDS. J Clin Pathol 1987;42:1055-64.
14. 14. Gerna G, Zipeto D, Parea M, et al. Early virus isolation, early structural antigen detection and DNA amplification by the polymerase chain reaction in polymorphonuclear leucocytes from AIDS patients with human cytomegalovirus viraemia. Molec Cell Probes 1991;5:365-74.
15. 15. Theise N, Rotterdam H, Dieterich D. Cytomegalovirus esophagitis in AIDS: Diagnosis by endoscopic biopsy. Am J Gastroenterol 1991;86: 1123-6.
16. 16. Blanshard C. Treatment of HIV-related cytomegalovirus disease of the gastrointestinal tract with foscarnet. AIDS 1992;5(suppl 1):S25-8.
17. 17. Dieterich D, Poles M, Dicker M, et al. Foscarnet treatment of cytomegalovirus gastrointestinal infections in acquired immunodeficiency syndrome patients who have failed ganciclovir induction. Am J Gastroenterol 1993;88:542-8.
18. 18. Chachoua A, Dieterich D, Krasinski 1C, et al. 9-(1,3-dihydroxy 2-propoxymethyl) guanine (ganciclovir) in the treatment of cytomegalovirus gastrointestinal disease with the acquired immunodeficiency syndrome. Ann Intern Med 1987;107:133.
19. 19. Wilcox C, Straub R, Schwartz D. Cytomegalovirus esophagitis in AIDS: A prospective evaluation of clinical response to ganciclovir therapy, relapse rate, and long-term outcome. Am J Med 1995;98: 169-76.
20. 20. Rene E, Marche C, Chevalier T, et al. Cytomegalovirus colitis in patients with acquired immunodeficiency syndrome. Dig Dis Seci 1988; 33:741-50.
21. 21. Connolly G, Forbes A, Gleeson J, et al. The value of barium enema and colonoscopy in patients infected with human immunodeficiency virus. AIDS 1990;4:687-9.
22. 22. Drew W, Miner R, Busch D, et al. Prevalence of resistance in patients receiving ganciclovir for serious cytomegalovirus infection. J Infect Dis 1991;163:716-9.
23. 23. Deray G, Martinez F, Levaltier B, et al. Foscarnet nephrotoxicity. Mechanism, incidence and prevention. Am J Nephrol 1989;9:316-21.