The mouse transketolase (TKT) gene: Cloning, characterization, and functional promoter analysis

Genomics

Volumn 48, Issue 2, 1998, Pages 209-220

  Salamon, Csaba ^a   Chervenak, Matthew ^a   Piatigorsky, Joram ^a   Sax, Christina M ^a  

^a NATIONAL EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTALLIN; GLUTATHIONE; TRANSKETOLASE;

ANIMAL TISSUE; ARTICLE; CONSENSUS SEQUENCE; CORNEA; DNA POLYMORPHISM; EXON; GENE CONTROL; GENE EXPRESSION; GENETIC ANALYSIS; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; SEQUENCE ANALYSIS; STRAIN DIFFERENCE; TATA BOX; TRANSCRIPTION INITIATION;

ANIMALIA; RODENTIA;

EID: 0032033818     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1997.5187     Document Type: Article

References (70)

1. Abedinia M., Pain T., Algar E. M., Holmes R. S. Bovine corneal aldehyde dehydrogenase: The major soluble corneal protein with a possible dual protective role for the eye. Exp. Eye Res. 51:1990;419-426.
2. Abedinia M., Layfield R., Jones S. M., Nixon P. F., Mattick J. S. Nucleotide and predicted amino acid sequence of a cDNA clone encoding part of human transketolase. Biochem. Biophys. Res. Commun. 183:1992;1159-1166.
3. Angel P., Imagawa M., Chiu R., Stein B., Imbra R. J., Rahmsdorf H. J., Jonat C., Herrlich P., Karin M. Phorbol ester-inducible genes contain a common cis element. Cell. 49:1987;729-739.
4. Bernacchia G., Schwall G., Lottspeich F., Salamini F., Bartels D. The transketolase gene family of the resurrection plant Craterostigma plantagineum. EMBO J. 14:1995;610-618.
5. Blass J. P., Gibson G. E. Abnormality of a thiamine-requiring enzyme in patients with Wernicke-Korsakoff syndrome. N. Engl. J. Med. 297:1977;1367-1370.
6. Blessing M., Zentgraf H., Jorcano J. L. Enhancer elements directing cell-type-specific expression of cytokeatin gene and changes of the epithelial cytoskeleton by transfections of hybrid cytokeratin genes. EMBO J. 6:1987;567-575.
7. Boesch J. S., Lee C., Lindahl R. G. Constitutive expression of class 3 aldehyde dehydrogenase in cultured rat corneal epithelium. J. Biol. Chem. 271:1996;5150-5157.
8. Briggs M. R., Kadonaga J. T., Bell S. P., Tjian R. Purification and biochemical characterization of the promoter-specific transcription factor, Sp1. Science. 234:1986;47-52.
9. 2. J. Biol. Chem. 266:1991;20447-20452.
10. Coy J. F., Dubel S., Kioschis P., Thomas K., Micklem G., Delius H., Poustka A. Molecular cloning of tissue-specific transcripts of a transketolase-related gene: Implications for the evolution of new vertebrate genes. Genomics. 32:1996;309-316.
11. Cuthbertson R. A., Tomarev S. I., Piatigorsky J. Taxon-specific recruitment of enzymes as major soluble proteins in the corneal epithelium of three mammals, chicken, and squid. Proc. Natl. Acad. Sci. USA. 89:1992;4004-4008.
12. Cvekl A., Piatigorsky J. Lens development and crystallin gene expression: Many roles for Pax-6. BioEssays. 18:1996;621-630.
13. de Sury D'Aspremont R., Toussaint B., Vignais P. M. Isolation of Hodobacter capsulatus transketolase: Cloning and sequencing of its structural tktA gene. Gene. 169:1996;81-84.
14. Devary Y., Gottlieb R. A., Lau L. F., Karin M. Rapid and preferential activation of the c-jun gene during the mammalian UV response. Mol. Cell. Biol. 11:1991;2804-2811.
15. Devary Y., Rosette C., DiDonato J. A., Karin M. NF-κB activation by ultraviolet light not dependent on a nuclear signal. Science. 261:1993;1442-1445.
16. Downes J., Holmes R. Development of aldehyde dehydrogenase and alcohol dehydrogenase in mouse eye: Evidence for light-induced changes. Biol. Neonate. 61:1992;118-123.
17. Eisinger J., Zakarian H., Plantamura A., Clairet D., Ayavou T. Studies of transketolase in chronic pain. J. Adv. Med. 5:1992;105-113.
18. el-Diery W. S., Kern S. E., Pietenpol J. A., Kinzler K. W., Vogelstein B. Definition of a consensus binding site for p53. Nature Genet. 1:1992;45-49.
19. Fleischmann R. D., Adams M. D., White O., Clayton R. A., Kirkness E. F., Kerlavage A. R., Bult C. J., Tomb J.-F., Dougherty B. A., Merrick J. M., McKenney K., Sutton G., FitzHugh W., Fields C. A., Gocayne J. D., Scott J. D., Shirley R., Liu L.-I., Glodek A., Kelley J. M., Weidman J. F., Phillips C. A., Spriggs T., Hedblom E., Cotton M. D., Utterback T. R., Hanna M. C., Nguyen D. T., Saudek D. M., Brandon R. C., Fine L. D., Fritchman J. L., Fuhrmann J. L., Geoghagen N. S. M., Gnehm C. L., McDonald L. A., Small K. V., Fraser C. M., Smith H. O., Venter J. C. Whole-genome random sequencing and assembly of Haemophilus influenza Rd. Science. 269:1995;496-512.
20. Fletcher T. S., Kwee I. L., Nakada T., Largman C., Martin B. M. DNA sequence of the yeast transketolase gene. Biochemistry. 31:1992;1892-1896.
21. Frederikse P. H., Dubin R. A., Haynes J. I., Piatigorsky J. Structure and alternate tissue-preferred transcription initiation of the mouse αβ-crystallin/small heat shock protein gene. Nucleic Acids Res. 22:1994;5686-5694.
22. Gonzalez P., Hernandez-Calzadilla C., Rao P. V., Rodriguez I. R., Zigler J. S., Borras T. Comparative analysis of the z-crystallin/quinone reductase gene in guinea pig and mouse. Mol. Biol. Evol. 11:1994;305-315.
23. Guo J., Sax C. M., Piatigorsky J., Yu F. X. Heterogenous expression of transketolase in ocular tissues. Curr. Eye Res. 16:1997;467-474.
24. Hainaut P., Milner J. Redox modulation of p53 conformation and sequence-specific DNA binding in vitro. Cancer Res. 53:1993;4469-4473.
25. Halder G., Callaerts P., Gehring W. J. Induction of ectopic eyes targeted expression of the eyeless gene in Drosophila. Science. 267:1995;1788-1792.
26. Hsu L. C., Chang W.-C., Chang C., Tsukamoto N., Yoshida A. The human aldehyde dehydrogenase 3 gene (ALDH3): Identification of a new exon and diverse mRNA isoforms, and functional analysis of the promoter. Gene Expression. 6:1996;3030-3037.
27. Iida A., Teshiba S., Mizobuchi K. Identification and characterization of the tktB gene encoding a second transketolase in Escherichia coli K-12. J. Bacteriol. 175:1993;5375-5383.
28. Iwaki A., Iwaki T., Goldman J., Liem R. K. Multiple mRNAs of rat brain α-crystallin β chain result from alternative transcriptional initiation. J. Biol. Chem. 265:1990;22197-22203.
29. Juhnke H., Krems B., Kotter P., Entian K.-D. Mutants that show increased sensitivity to hydrogen peroxide reveal an important role for the pentose phosphate pathway in protection of yeast against oxidative stress. Mol. Gen. Genet. 252:1996;456-464.
30. Kays W. T., Piatigorsky J. Aldehyde dehydrogenase class 3 expression: Identification of a cornea-preferred gene promotor in transgenic mice. Proc. Natl. Acad. Sci. 94:1997;13594-13599.
31. Klemsz M. J., McKercher S. R., Celeda A., Van Beveren C., Maki R. A. The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene. Cell. 61:1990;113-124.
32. Kochetov G. A. Transketolase from yeast, rat liver, and pig liver. Methods in Enzymology. 1982;Academic Press, New York. p. 209-223.
33. Koroma B. M., Yang J.-M., Sundin O. H. The Pax-6 homeobox gene is expressed throughout the corneal and conjunctiva epithelia. Invest. Ophthalmol. Visual Sci. 38:1997;108-120.
34. Kosower N. S., Kosower E. M., Wertheim B., Correa W. S. Diamide, a new reagent for the intracellular oxidation of glutathione to the disulfide. Biochem. Biophys. Res. Commun. 37:1969;593-596.
35. Kraft H. J., Hendriks W., de Jong W. W., Lubsen N. H., Schoenmakers J. G. G. Duck lactate dehydrogenase β/ε-crystallin gene: Lens recruitment of a GC-promoter. J. Mol. Biol. 229:1993;849-859.
36. Lapsys N. M., Layfield R., Baker E., Callen D. F., Sutherland G. R., Abedinia M., Nixon P. F., Mattick J. S. Chromosomal location of the human transketolase gene. Cytogenet. Cell Genet. 61:1992;274-275.
37. Li H.-S., Yang J.-M., Jacobson R. D., Pasko D., Sundin O. Pax-6 is first expressed in a region of ectoderm anterior to the early neural plate: Implications for stepwise determination of the lens. Dev. Biol. 162:1994;181-194.
38. Londsale D., Shamberger R. J. Red cell transketolase as an indicator of nutritional deficiency. Am. J. Clin. Nutr. 33:1980;205-207.
39. Masure S., Nys G., Fiten P., Van Damme J., Opdenakker G. Mouse gelatinase B: cDNA cloning, regulation of expression and glycosylation in WEHI-3 macrophages and gene organisation. Eur. J. Biochem. 218:1993;129-141.
40. Metzger M., Hollenberg C. Isolation and characterization of the Pichia stipitis tansketolase gene and expression in a xylose-utilising Saccharomyces cerevisiae transformant. Appl. Microbiol. Biotechnol. 42:1994;319-325.
41. Mitchell J., Cenedella R. J. Quantitation of ultraviolet light-absorbing fractions of the cornea. Cornea. 14:1995;266-272.
42. Mitchell P. J., Timmons P. M., Herbert J. M., Rigby P. W. J., Tjian R. Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis. Genes Dev. 5:1991;105-119.
43. Mukherjiee A. S., Svoronos S., Ghazhanfari A., Martin P. R., Fisher A., Roecklein B., Rodbard D., Staton R., Behar D., Berg C. J., Munjunath R. Transketolase abnormality in cultured fibroblasts from familial chronic alcoholic men and their male offspring. J. Clin. Invest. 79:1987;1039-1043.
44. Nixon P. F., Kaczmarek M. J., Tate J., Kerr R. A., Roice J. An erythrocyte transketolase isoenzyme pattern associated with the Wernicke-Korsakoff syndrome. Eur. J. Clin. Invest. 14:1984;278-281.
45. Piatigorsky J. Lens crystallins: Innovation associated with changes in gene regulation. J. Biol. Chem. 267:1992;4277-4280.
46. Piatigorsky J. Puzzle of crystallin diversity in eye lenses. Dev. Dyn. 196:1993;267-272.
47. Piatigorsky J. Gene sharing in lens and cornea: Facts and implications. Prog. Retina Eye Res. 1997.
48. Racker E. Transketolase. Boyer P., Lardy H., Myrback K. The Enzymes. 1961;397-406 Academic Press, New York.
49. Reddan J. R., Chepelinsky A. B., Dziedzic D. C., Piatigorsky J., Goldenberg E. M. Retention of lens specificity in long-term cultures of diploid rabbit lens epithelial cells. Differentiation. 33:1986;168-174.
50. Ronai Z., Rutberg S., Yang Y. M. UV-responsive element (TGACAACA) from rat fibroblasts to human melanomas. Environ. Mol. Mutagen. 23:1994;157-163.
51. Sax C. M., Ilagan J. G., Piatigorsky J. Functional redundancy of the DE-1 and αA-CRYβP1 regulatory sites of the mouse αA-crystallin promoter. Nucleic Acids Res. 21:1993;2633-2640.
52. Sax C. M., Salamon C., Kays W. T., Guo J., Yu F. X., Cuthbertson R. A., Piatigorsky J. Transketolase is a major protein in the mouse cornea. J. Biol. Chem. 271:1996;33568-33574.
53. Schaaff-Gerstenschlager I., Mannhaupt G., Vetter I., Zimmermann F. K., Feldmann H. TKL2, a second transketolase gene of Saccharomyces cerevisiae: Cloning, sequence and deletion analysis of the gene. Eur. J. Biochem. 217:1993;487-492.
54. Schaferjohann J., Yoo J.-G., Kusian B., Bowien B. The cbb operons of the facultative chemoautotroph Alcaligenes eutrophus encode phosphoglycolate phosphatase. J. Bacteriol. 175:1993;7329-7340.
55. Schenk G., Layfield R., Candy J. M., Duggleby R. G., Nixon P. F. Molecular evolutionary analysis of the thiamine-diphosphate-dependent enzyme, transketolase. J. Mol. Evol. 44:1997;552-572.
56. Schimmer B. P., Tsao J., Czerwinski W. Amplification of the transketolase gene in desensitization-resistant mutant Y1 mouse adrenocortical tumor cells. J. Biol. Chem. 271:1996;4993-4998.
57. Sen R., Baltimore D. Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism. Cell. 46:1986;705-716.
58. Shapiro M. B., Senapathy P. RNA splice junctions of different classes of eukaryotes: Sequence statistics and functional implications in gene expression. Nucleic Acids Res. 15:1987;7155-7174.
59. Sheu K.-F. R., Clarke D. D., Kim Y.-T., Blass J. P., Jarding B. J., Decicco J. Studies of transketolase abnormality in Alzheimer's disease. Arch. Neurol. 45:1988;841-845.
60. Slekar K. H., Kosman D. J., Culotta V. C. The yeast copper/zinc superoxide dismutase and the pentose phosphate pathway play overlapping roles in oxidative stress. J. Biol. Chem. 271:1996;28831-28836.
61. Sprenger G. A. Nucleotide sequence of the Escherichia coli K-12 transketolase (tkt) gene. Biochim. Biophys. Acta. 1216:1993;307-310.
62. Sundstrom M., Lindqvist Y., Schneider G., Hellman U., Ronne H. Yeast YKL1 gene encodes a transketolase that is required for efficient glycolysis and biosynthesis of aromatic amino acids. J. Biol. Chem. 268:1993;24346-24352.
63. Takimoto K., Lindahl R., Dunn T. J., Pitot H. C. Structure of the 5′ flanking region of class 3 aldehyde dehydrogenase in the rat. Arch. Biochem. Biophys. 312:1994;539-546.
64. Tombaccini D., Mocali A., Paoletti F. Characteristic transketolase alterations in dermal fibroblasts of Alzheimer patients are modulated by culture conditions. Exp. Mol. Pathol. 60:1994;140-146.
65. van den Bergh E. R., Baker S. C., Ragges R. J., Terpstra P., Dijkhuizen L., Meijer W. G. Primary structure and phylogeny of the calvin cycle enzymes transketolase and fructose biphosphate aldolase of Xanthobacter flavus. J. Bacteriol. 178:1996;888-893.
66. Walther C., Gruss P. Pax-6, a murine paired box gene, is expressed in the developing CNS. Development. 113:1991;1435-1449.
67. Wistow G. J., Piatigorsky J. Lens crystallins: The evolution and expression of proteins for a highly specialized tissue. Annu. Rev. Biochem. 57:1988;479-504.
68. Wu R. L., Galvin S., Wu S. K., Xu C., Blumenberg M., Sun T. T. A 300 bp 5′-upstream sequence of a differentiation-dependent rabbit K3 keratin gene can serve as a keratinocyte-specific promoter. J. Cell. Sci. 105:1993;303-316.
69. Yamada T., Nakamura T., Westphal H., Russell P. Synthesis of α-crystallin by a cell line derived from the lens of a transgenic animal. Curr. Eye Res. 9:1989;31-37.
70. Zigman S. Photobiology of the lens. Maisel H. The Ocular Lens: Structure, Function, and Pathology. 1985;301-347 Dekker, New York.