Antimalarial drugs inhibit phospholipase A2 activation and induction of interleukin 1β and tumor necrosis factor α in macrophages: Implications for their mode of action in rheumatoid arthritis

General Pharmacology

Volumn 30, Issue 3, 1998, Pages 357-366

  Bondeson, Jan ^a   Sundler, Roger ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Antimalarials; Arachidonate; Chloroquine; Hydroxychloroquine; Interleukin 1; Phospholipase A2; Quinacrine; Tumor necrosis factor

Indexed keywords

ANTIMALARIAL AGENT; CHLOROQUINE; CYTOKINE; HYDROXYCHLOROQUINE; ICOSANOID; INTERLEUKIN 1BETA; MEPACRINE; PHOSPHOLIPASE A2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; FEMALE; IMMUNOBLOTTING; MACROPHAGE; MOUSE; NONHUMAN; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION;

ANIMALS; ANTIMALARIALS; CHLOROQUINE; EICOSANOIDS; FEMALE; INTERLEUKIN-1; MACROPHAGES, PERITONEAL; MICE; PHOSPHOLIPASES A; QUINACRINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0032033594     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-3623(97)00269-3     Document Type: Article

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