Changes in E2F complexes containing retinoblastoma protein family members and increased cyclin-dependent kinase inhibitor activities during terminal differentiation of cardiomyocytes

Journal of Molecular and Cellular Cardiology

Volumn 30, Issue 3, 1998, Pages 563-578

  Flink, Irwin L ^a   Oana, Shinji ^a   Maitra, Niranjan ^a   Bahl, Joseph J ^a   Morkin, Eugene ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

Cardiomyocyte; Cell cycle; Cyclin dependent kinase inhibitor; Retinoblastoma protein; Terminal differentiation

Indexed keywords

CYCLIN A; CYCLIN D1; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN E; CYCLINE; DNA; MESSENGER RNA; PROTEIN P21; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME INHIBITION; FETUS; FETUS DEVELOPMENT; GENE EXPRESSION REGULATION; HEART MUSCLE CELL; MYOBLAST; NEWBORN; NONHUMAN; PERINATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0032032373     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1997.0620     Document Type: Article

References (48)

1. BEIJERSBERGEN RL, CARLEE L, KERKHOVEN RM, BERNARDS R, 1995. Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes. Gene Dev 9: 1340-1353.
2. BRIZUELA L, DRAETTA G, BEACH D, 1987. p13suc1 acts in fission yeast cell division as a component of the p34cdc2 protein kinase. EMBO J 6: 3507-3514.
3. BUCKINGHAM M, 1992. Making muscle in mammals. Trends Genet 8: 144-148.
4. CAO L, FAHA B, DEMBSKI M, TSAI L-H, HARLOW E, DYSON N, 1993. Independent binding of the retinoblastoma protein and p107 to the transcription factor E27. Nature 355: 176-179.
5. CARUSO M, MARTELLI F, GIORDANO A, FELSANI A, 1993. Regulation of myoD gene transcription and protein function by the transforming domains of the adenovirus E1A oncoprotein. Oncogene 8: 267-278.
6. CHELLAPPPAN S, HIEBERT S, MUDRYL M, HOROWITZ JM, NEVINS JR, 1991. The E2F transcription factor is a cellular target for the RB protein. Cell 65: 1053-1061.
7. COBRINIK D, WHYTE P, PEEPER DS, JACKS T, WEINBERG RA, 1993. Cell cycle-specific association of E2F with the p130 E1A-binding protein. Genes Dev 7: 2392-2404.
8. CORBEIL HB, WHYTE P, BRANTON PE, 1995. Characterization of transcription factor E2F complexes during muscle and neuronal differentiation. Oncogene 112: 909-920.
9. DAUD A, FIELD LJ, 1993. Identification of SV40 large T-antigen-associated protein in cardiomyocytes from transgenic mice. Heart Failure 9: 183-198.
10. cip1/waf1 undergo normal development, but are defective in G1 checkpoint control. Cell 82: 675-684.
11. DRESSLER LG, BARTOW SA, 1989. DNA flow cytometry in solid tumors: practical aspects and clinical applications. Semin Diag Path 6: 55-82.
12. Waf1, a potential mediator of p53 tumor suppression. Cell 75: 817-825.
13. FAHA B, EWEN M, TSAI L-H, LIVINGSTON D, HARLOW E, 1992. Interaction between human cyclin A and adenovirus E1A-associated p107 protein. Science 255: 87-90.
14. FRANGAKIS CJ, BAHL JJ, MCDANIELS H, BRESSLER R, 1980. Tolerance to physiological calcium by isolated myocytes from the adult rat heart; an improved cellular preparation. Life Sci 27: 815-825.
15. GU W, SCHNEIDER JW, CONDORELLI G, KAUSHAL S, MAHDAVI V, NADAL-GINARD B, 1993. Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation. Cell 72: 309-324.
16. GUO K, WANG J, ANDRES V, SMITH RC, WALSH K, 1995. Myo-D induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation. Mol Cell Biol 15: 3823-3829.
17. HALEVY O, NOVITCH BG, SPICER DB, SKAPEK SS, RHEE J, HANNON GJ, BEACH D, LASSAR AB, 1995. Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science 267: 1018-1021.
18. HELIN K, LEES JA, VIDAL M, DYSON N, HARLOW E, FATTAEY A, 1992. A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F. Cell 70: 337-350.
19. HIEBERT S, CHELLAPAN SP, HOROWITZ J, NEVINS JR, 1992. The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F. Genes Dev 6: 177-185.
20. KANG MS, KOH GY, 1997. Differential and dramatic changes of cyclin-dependent kinase activities in cardiomyocytes during the normal period. J Mol Cell Cardiol 29: 1767-1777.
21. KIM KK, SOONPAA MH, DAUD AI, KOH GY, KIM SJ, FIELD LJ, 1994. Tumor suppressor gene expression during normal and pathologic myocardial growth. J Biol Chem 269: 22607-22613.
22. LAM EW, WATSON RJ, 1993. An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription. EMBO J 12: 2705-2713.
23. LASSAR AB, SKAPEK SX, NOVITCH B, 1994. Regulatory mechanisms that coordinate skeletal muscle differentiation and cell cycle withdrawal. Curr Opin Cell Biol 6: 788-794.
24. LI F, WANG X, CAPASSO JM, GERDES M, 1996. Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development. J Mol Cell Cardiol 28: 1737-1746.
25. LI F, WANG X, BUNGER PC, GERDES M, 1997. Formation of binucleated cardiac myocytes in rat heart: II. Cytoskeletal organization. J Mol Cell Cardiol 29: 1541-1551.
26. LI Y, GRAHAM C, LACY S, DUNCAN AMV, WHYTE P, 1993. The adenovirus E1A-associated 130-kd protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E. Genes Dev 7: 2366-2377.
27. LIU Q, YAN H, DAWES NJ, MOTTINO GA, FRANK JS, ZHU H, 1996. Insulin-like growth factor II induces DNA synthesis in fetal ventricular myocytes in vitro. Circ Res 79: 716-726.
28. waf1/cip1 expression through mitogen activated protein kinase signaling pathway. Cancer Res 56: 31-35.
29. MAIONE R, FIMIA G, HOLMAN P, SCHAFFHAUSEN B, AMATI P, 1994. Retinoblastoma antioncogene is involved in the inhibition of myogenesis by polyomavirus large T-antigen. Cell Growth Differ 5: 231-237.
30. MARINO TA, HALDAR S, WILLIAMSON EC, BEAVERSON K, WALTER RA, MARINO DR, BEATTY C, LIPSON KE, 1996. Proliferating cell nuclear antigen in developing and adult rat cardiac muscle cells. Circ Res 69: 1353-1360.
31. MATSUSHIME H, QUELLE DE, SHURTLEFF SA, SHIBUYA M, SHERR CJ, KATO J-Y 1994. D-type cyclin-dependent kinase activity in mammalian cells. Mol Cell Biol 14: 2066-2076.
32. MCGILL CJ, BROOKS G, 1995. Cell cycle control mechanisms and their role in cardiac growth. Cardiovasc Res 30: 557-569.
33. NEVINS JR, 1992. E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science 258: 424-429.
34. PARKER SB, EICHELE G, ZHANG P, RAWLS A, SANDS AT, BRADLEY A, OLSON EN, HARPER W, ELLEDGE S, 1995. p53-independent expression of p21cip1 in muscle and other terminally differentiating cells. Science 267: 1024-1027.
35. POLYAK K, KATO JY, SOLOMON MJ, SHERR CJ, MASSAGUE J, ROBERTS JM, KOFF A, 1994. p27kip1, a cyclin-cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest. Genes Dev 8: 9-22.
36. QIN XQ, LIVINGSTON DM, KAELIN WG JR, ADAMS PD, 1994. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc Natl Acad Sci USA 91: 10918-10922.
37. QUAINI F, CIGOLA E, LAGASTRA C, SACCANI G, QUAINI E, ROSSI C, OLIVETTI G, ANVERSA P, 1994. End-stage cardiac failure in humans coupled with the induction of proliferating cell nuclear antigen and nuclear mitotic division in ventricular myocytes. Circ Res 75: 1050-1063.
38. RUMYANSTEV PP, 1973. Post-injury DNA synthesis, mitosis and ultrastructural reorganization of adult frog cardiac myocytes. An electron microscopic-autoradiographic study. Zeit Zellforsch Mikroskop Anat 139: 431-450.
39. RUMYANSTEV PP, 1991. In: Rumyanstev PP (ed.) Growth and Hyperplasia of Cardiac Muscle Cells. London: Harwood Academic Publisher, 70-157.
40. SADOSHIMA J, AOKI H, IZUMO S, 1997. Angiotensin II and serum differentially regulate expression of cyclins, activity of cyclin-dependent kinases, and phosphorylation of retinoblastoma gene product in neonatal cardiac myocytes. Circ Res 80: 228-241.
41. -/- muscle cells. Science 264: 1467-1471.
42. SEN A, DUNNMON PS, HENDERSON A, GERARD RD, CHIEN KR, 1988. Terminally differentiated neonatal myocardial cells proliferate and maintain specific differentiated functions following expression of SV40 large T antigen. J Biol Chem 263: 19132-19136.
43. SHIN EK, SHIN A, PAULDING C, SCHAFFHAUSEN B, YEE AS, 1995. Multiple change in E2f function and regulation occur upon muscle differentiation. Mol Cell Biol 15: 2252-2262.
44. 1 cell state. Mol Cell Biol 16: 6965-6976.
45. SOONPAA MH, KIM KK, PAJAK L, FRANKLIN M, FIELD LJ, 1996. Cardiomyocyte DNA synthesis and multinucleation during murine development. Am J Physiol 271: H2183-H2189.
46. TOYOSHIMA H, HUNTER T, 1994. p27, a novel inhibitor of G1 cyclin-cdk protein kinase activity, is related to p21. Cell 78: 67-74.
47. XIONG Y, HANNON GJ, ZHANG H, CASSO D, KOBAYASHI R, BEACH D, 1993. p21 is a universal inhibitor of cyclin kinases. Nature 366: 701-704.
48. YOSHIZUMI M, LEE W-S, HSIEH C-M, TSAI J-C, LI J, PERELLA MA, PATTERSON C, ENDEGE WO, SCHLEGEL R, LEE M-E, 1996. Disappearance of cyclin A correlates with permanent withdrawal of cardiomyocytes from the cell cycle in human and rat hearts. J Clin Invest 95: 2275-2280.