Fetal mouse NK cell clones are deficient in Ly49 expression, share a common broad lytic specificity, and undergo continuous and extensive diversification in vitro

Journal of Immunology

Volumn 160, Issue 5, 1998, Pages 2197-2206

  Manoussaka, Maria S ^a   Smith, Rachel J ^a   Conlin, Victoria ^a   Toomey, Jennifer A ^a   Brooks, Colin G ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 2; INTERLEUKIN 4;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CLONING; CELL CYCLE; FETUS; GENE EXPRESSION; GENE EXPRESSION REGULATION; HYPOTHESIS; MOUSE; NATURAL KILLER CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; STEM CELL;

ANIMALS; ANTIGENS, LY; ANTIGENS, SURFACE; CELL LINE; CLONE CELLS; CYTOTOXICITY TESTS, IMMUNOLOGIC; CYTOTOXICITY, IMMUNOLOGIC; EMBRYONIC AND FETAL DEVELOPMENT; IMMUNOPHENOTYPING; KILLER CELLS, NATURAL; LECTINS, C-TYPE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED DBA; THYMUS GLAND;

EID: 0032032202     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (61)

1. Ljunggren, H.-G., and K. Kärre. 1990. In search of the "missing self": MHC molecules and NK recognition. Immunol. Today 11:237.
2. + IL2-activated natural killer cells. Nature 358:66.
3. Moretta, A., C. Bottino, M. Vitale, D. Pende, R. Biassoni, M. C. Mingari, and L. Moretta. 1996. Receptors for HLA class I molecules in human natural killer cells. Annu. Rev. Immunol. 14:67.
4. Brown, M. G., A. A. Scalzo, K. Matsumoto, and W. M. Yokoyama. 1997. The natural killer gene complex: a genetic basis for understanding natural killer cell function and innate immunity. Immunol. Rev. 155:53.
5. Takei, F., J. Brennan, and D. L. Mager. 1997. The Ly49 family: genes, proteins, and recognition of class I MHC. Immunol. Rev. 155:67.
6. Karlhofer, F. M., R. Hunziker, A. Reichlin, D. H. Margulies, and W. M. Yokoyama. 1994. Host MHC class I molecules modulate in vivo expression of a NK cell receptor. J. Immunol. 153:2407.
7. Olsson, M. Y., K. Kärre, and C. L. Sentman. 1995. Altered phenotype and function of natural killer cells expressing the major histocompatibility complex receptor Ly-49 in mice transgenic for its ligand. Proc. Natl. Acad. Sci. USA 92: 1649.
8. Held., W., J. R. Dorfman, M.-F. Wu, and D. H. Raulet. 1996. Major histocompatibility complex class I-dependent skewing of the natural killer cell Ly49 repertoire. Eur. J. Immunol. 26:2286.
9. Raulet, D. H., W. Held, I. Correa, J. Dorfman, M.-F. Wu, and L. Corral. 1997. Specificity, tolerance, and developmental regulation of natural killer cells defined by expression of class I-specific Ly49 receptors. Immunol. Rev. 155:41.
10. Höglund, P., J. Sunbäck, M. Y. Olsson-Alheim, M. Johansson, M. Salcedo, C. Öhlén, H.-G. Ljunggren, C. L. Sentman, and K. Kärre. 1997. Immunol. Rev. 155:11.
11. Ryan, J. C., and W. E. Seaman. 1997. Divergent functions of lectin-like receptors on NK cells. Immunol. Rev. 155:79.
12. Mason, L. H., S. K. Anderson, W. M. Yokoyama, H. R. C. Smith, R. Winkler-Pickett, and J. R. Ortaldo. 1996. The Ly49D receptor activates murine natural killer cells. J. Exp. Med. 184:2119.
13. Chambers, W. H., N. L. Vujanovic, A. B. DeLeo, M. W. Olszowy, R. B. Herberman, and J. C. Hiserodt. 1989. Monoclonal antibody to a triggering structure expressed on rat natural killer cells and adherent lymphokine-activated killer cells. J. Exp. Med. 169:1373.
14. Bezouska, K., C.-T. Yuen, J. O'Brien, R. A. Childs, W. Chai, A. M. Lawson, K. Drbal, A. Fiserova, M. Pospisil, and T. Feizi. 1914. Oligosaccharide ligands for NKR-P1 protein activated NK cells and cytotoxicity. Nature 372:150.
15. Ryan, J. C., J. Truck, E. C. Niemi, W. M. Yokoyama, and W. E. Seaman. 1992. Molecular cloning of the NK1.1 antigen, a member of the NKR-P1 family of natural killer cell activation molecules. J. Immunol. 149:1631.
16. + cells. J. Immunol. 136:3124.
17. Karlhofer, F. M., and W. M. Yokoyama. 1991. Stimulation of murine natural killer (NK) cells by a monoclonal antibody specific for the NK1.1 antigen: IL-2 activated NK cells possess additional specific stimulation pathways. J. Immunol. 146:3662.
18. Sentman, C. L., J. Hackett, T. A. Moore, M. M. Tutt, M. Bennett, and V. Kumar. 1989. Pan natural killer cell monoclonal antibodies and their relationship to the NK1.1 antigen. Hybridoma 8:605.
19. Thiele, D. L., and P. E. Lipsky. 1989. The role of cell surface recognition structures in the initiation of MHC-unrestricted "promiscuous" killing by T cells. Immunol. Today 10:375.
20. Siliciano, R. F., J. C. Pratt, R. E. Schmidt, J. Ritz, and E. L. Reinherz. 1985. Activation of cytolyic T lymphocyte and natural killer cell function through the T11 sheep erythrocyte binding protein. Nature 317:428.
21. Azuma, M., M. Cayabyab, C. Buck, J. H. Phillips, and L. L. Lanier. 1992. Involvement of CD28 in major histocompatibility complex-unrestricted cytotoxicity mediated by a human NK leukemia cell line. J. Immunol. 149:1115.
22. Chambers, B. J., M. Salcedo, and H.-G. Ljunggren. 1996. Triggering of natural killer cells by costimulatory molecule CD80 (B7.1). Immunity 5:311.
23. Carbone, E., G. Ruggiero, G. Terrazzano, C. Palomba, C. Manzo, S. Fontana, H. Spits, K. Kärre, and S. Zappacosta. 1997. A new mechanism of NK cell cytotoxicity activation: the CD40-CD40 ligand interaction. J. Exp. Med. 185: 2053.
24. Thomas, M. L. 1989. The leukocyte common antigen family. Annu. Rev. Immunol. 7:339.
25. Kasai, M., J. C. LeClerc, F.-W. Shen, and H. Cantor. 1979. Identification of Ly5 on the surface of "natural killer" cells in normal and athymic inbred mouse strains. Immunogenetics 8:153.
26. Seaman, W. E., N. Talal, L. A. Herzenberg, L. A. Herzenberg, and J. A. Ledbetter. 1981. Surface antigens on mouse natural killer cells: use of monoclonal antibodies to inhibit or enrich cytotoxicity activity. J. Immunol. 127: 982.
27. Sparrow, R. L., and I. F. C. McKenzie. 1983. A function for human T200 in natural killer cytolysis. Transplantation 36:166.
28. Newman, W. 1982. Selective blockade of human natural killer cells by a monoclonal antibody. Proc. Natl. Acad. Sci. USA 79:3858.
29. Newman, W., L. D. Fast, and L. M. Rose. 1983. Blockade of NK cell lysis is a property of monoclonal antibodies that bind to distinct regions of T-200. J. Immunol. 131:1742.
30. Gilbert, C. W., M. H. Zaroubian, and W. J. Esselman. 1988. Poly-N-acetyllactosamine structures on murine cell surface T200 glycoprotein participate in natural killer cell binding to YAC-1 targets. J. Immunol. 140:2821.
31. Bajpai, A., and Z. Brahmi. 1994. Target cell-induced inactivation of cytolytic lymphocytes. Role and regulation of CD45 and calcyculin A-inhibited phosphatase in response to interleukin-2. J. Biol. Chem. 269:18864.
32. lck-mediated tyrosine phosphorylation and IFN-γ production. J. Immunol. 155:5241.
33. Brooks, C. G., A. Georgiou, and R. K. Jordan. 1993. The majority of immature fetal thymocytes can be induced to proliferate to IL-2 and differentiate into cells indistinguishable from mature natural killer cells. J. Immunol. 151:6645.
34. Brooks, C. G., and G. R. Flannery. 1980. Quantitative studies of natural immunity to solid tumours in rats: persistence of natural immunity throughout reproductive life, and absence of suppressor cells in infant rats. Immunology 39:187.
35. Manoussaka, M., A. Georgiou, B. Rossiter, S. Shrestha, J. A. Toomey, P. V. Sivakumar, M. Bennett, V. Kumar, and C. G. Brooks. 1997. Phenotypic and functional characterization of long-lived NK cell lines of different maturational status obtained from mouse fetal liver. J. Immunol. 158:112.
36. Shevach, E. M., and P. E. Korty. 1989. Ly-6: a multigene family in search of a function. Immunol. Today 10:195.
37. Linnemeyer, P. A., J. M. Tsuji, S. Gill, and S. B. Pollack. 1994. Hamster monoclonal antibodies to murine natural killer cells. Nat. Immun. 13:49.
38. Lefrancois, L., L. Puddington, C. E. Machamer, and M. J. Bevan. 1985. Acquisition of cytotoxic T lymphocyte-specific carbohydrate differentiation antigens. J. Exp. Med. 162:1275.
39. + IL2-activated natural killer cells. Nature 358:66.
40. Correa, I., L. Corral, and D. H. Raulet. 1994. Multiple natural killer cell-activating signals are inhibited by major histocompatibility complex class I expression in target cells. Eur. J. Immunol. 24:1323.
41. Mason, L. H., J. R. Ortaldo, H. A. Young, V. Kumar, M. Bennett, and S. K. Anderson. 1995. Cloning and functional characteristics of murine large granular lymphocyte-1: a number of the Ly49 gene family (Ly-49G2). J. Exp. Med. 182:293.
42. Sentman, C. L., M. Y. Olsson, M. Salcedo, P. Höglund, V. Lendahl, and K. Kärre. 1994. H-2 allele-specific protection from NK cell lysis in vitro for lymphoblasts but not tumor targets: protection mediated by α1/α2 domains. J. Immunol. 153:5482.
43. Karlhofer, F. M., M. M. Orikuela, and W. M. Yokoyama. 1995. Ly-49-independent natural killer (NK) cell specificity revealed by NK cell clones derived from p53-deficient mice. J. Exp. Med. 181:1785.
44. Baume, D. M., M. A. Caligiuri, T. J. Manley, J. F. Daley, and J. Ritz. 1990. Differential expression of CD8α and CD8β associated with MHC-restricted and non-MHC-restricted cytolytic effector cells. Cell. Immunol. 131:352.
45. Torres-Nagel, N., E. Kraus, M. H. Brown, G. Tiefenthaler, R. Mitnacht, A. F. Williams, and T. Hünig. 1992. Differential thymus dependence of rat CD8 isoform expression. Eur. J. Immunol. 22:2841.
46. Pesussia, B., V. Fanning, and G. Trinchieri. 1983. A human NK and K cell subset shares with cytotoxic T cells expression of the antigen recognized by antibody OKT8. J. Immunol. 131:223.
47. Cantrell, D. A., R. A. Robins, C. G. Brooks, and R. W. Baldwin. 1982. Phenotype of rat natural killer cells denned by monoclonal antibodies marking rat lymphocyte subsets. Immunology 45:97.
48. Havran, W. L., D. W. Lancki, R. L. Moldwin, D. P. Dialynas, and F. W. Fitch. 1988. Characterization of an anti-Ly6 monoclonal antibody which defines and activates cytolytic T lymphocytes. J. Immunol. 140:1034.
49. Johnson, R., D. W. Lancki, and F. W. Fitch. 1993. Accessory molecules involved in antigen-mediated cytolysis and lymphokine production by cytotoxic T lymphocyte subsets. I. Identification of functions for the T cell surface molecules Ly-6C and Thy-1. J. Immunol. 151:2986.
50. Luqman, M., P. Johnson, I. S. Trowbridge, and K. Bottomly. 1991. Differential expression of the alternatively spliced exons of murine CD45 in Th1 and Th2 clones. Eur. J. Immunol. 21:12.
51. + T cell subsets. J. Immunol. 148:4054.
52. + suppressor effector T cell clones by cytokine production and CD45 isoforms. J. Immunol. 150:2121.
53. Simon, M., J. Zieg, M. Silverman, G. Mandel, and R. Doolittle. 1980. Phase variation: evolution of a controlling element. Science 209:1370.
54. Henikoff, S. 1994. A reconsideration of the mechanism of position effect. Genetics 138:1.
55. Razin, A., and H. Cedar. 1994. DNA methylation and genomic imprinting. Cell 77:473.
56. Festenstein, R., M. Tolaini, P. Corbella, C. Mamalki, J. Parrington, M. Fox, A. Milou, M. Jones, and D. Kioussis. 1996. Locus-control region function and heterochromatin-induced position effect variegation. Science 271:1123.
57. Burns, G. F., J. A. Werkmeister, and T. Triglia. 1994. A novel antigenic cell surface protein associated with T200 is involved in the post-activation stage of human NK cell-mediated lysis. J. Immunol. 133:1391.
58. Dianzani, U., V. Redoglia, F. Malavasi, M. Bragardo, A. Pileri, C. A. Janeway, and K. Bottomly. 1992. Molecular associations on the T cell surface correlate with immunological memory. Eur. J. Immunol. 22:365.
59. Charbonneau, H., N. K. Tonks, K. A. Walsh, and E. H. Fischer. 1988. The leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphatase. Proc. Natl. Acad. Sci. USA 85:7182.
60. Olcese, I., P. Lang, F. Vély, A. Cambiaggi, D. Marquet, M. Blery, K. L. Hippen, R. Biassoni, A. Moretta, L. Moretta, J. C. Cambier, and E. Vivier. Human and mouse killer-cell inhibitory receptors recruit PTPIC and PTPID protein tyrosine phosphatases. J. Immunol. 156:4531.
61. Toomey, J. A., S. Shrestha, S. A. de la Rue, F. Gays, J. H. Robinson, Z. M. A. Chrzanowska-Lightowlers, and C. G. Brooks. 1998. Major histocompatibility class I expression protects target cells from lysis by Lyx49-deficient fetal natural killer cells. Eur. J. Immunol. 28. in press.