Histopathological evaluation of liver fibrosis: Quantitative image analysis vs semi-quantitative scores: Comparison with serum markers

Journal of Hepatology

Volumn 28, Issue 3, 1998, Pages 439-446

  Pilette, Christophe ^a   Rousselet, Marie Christine ^a   Bedossa, Pierre ^d   Chappard, Daniel ^b   Oberti, Frédéric ^a   Rifflet, Hervé ^a   Maïga, Moussa Y ^a   Gallois, Yves ^c   Calès, Paul ^a  

^a UFR de medecine   (France)

^b ANGERS UNIVERSITY HOSPITAL   (France)

^c UFR de Médecine   (France)

^d BICÊTRE HOSPITAL   (France)

Author keywords

Cirrhosis; Fibrosis; Histological score of fibrosis; Hyaluronate; Image analysis; Prothrombin index; Serum markers of fibrosis

Indexed keywords

ALPHA 2 MACROGLOBULIN; APOLIPOPROTEIN A1; BIOLOGICAL MARKER; HYALURONIC ACID; LAMININ; PROCOLLAGEN TYPE 3 AMINOPROPEPTIDE; PROTHROMBIN; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; ALCOHOL LIVER DISEASE; ARTICLE; CHRONIC LIVER DISEASE; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMAGE PROCESSING; INFLAMMATION; LIVER BIOPSY; LIVER FIBROSIS; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RADIOIMMUNOASSAY; REGRESSION ANALYSIS; REPRODUCIBILITY;

EID: 0032031620     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(98)80318-8     Document Type: Article

References (35)

1. Tiné F, Pagliaro L. Cirrhosis and its recognition in asymptomatic subjects with aminotransferases elevation. Hepatology. 11:1990;516-517.
2. Soloway RD, Baggenstoss AH, Schoenfield LJ, Summerskill WHJ. Observer error and sampling variability tested in evaluation of hepatitis and cirrhosis by liver biopsy. Dig Dis Sci. 16:1971;1082-1086.
3. Ishak K, Baptista A, Bianchi L, Callea F, De Groote J, Gudat F, et al. Histological grading and staging of chronic hepatitis. J Hepatol. 22:1995;696-699.
4. Knodell RG, Ishak KG, Black WC, Chen TS, Craig R, Kaplowitz N, et al. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology. 1:1981;431-435.
5. Bedossa P, Bioulac-Sage P, Callard P, Chevallier M, Degott C, Deugnier Y, et al. Intraobserver and interobserver variations in liver biopsy interpretation in patients with chronic hepatitis C. Hepatology. 20:1994;15-20.
6. Chevallier M, Guerret S, Chossegros P, Gerard F, Grimaud JA. A histological semiquantitative scoring system for evaluation of hepatic fibrosis in needle biopsy specimens: comparison with morphometric studies. Hepatology. 20:1994;349-355.
7. Rubio CA, Porwitt A. Quantitation of fibrosis in liver biopsies. Anal Quant Cytol Histol. 10:1988;107-109.
8. Feldmann G. Critical analysis of the methods used to morphologically quantify hepatic fibrosis. J Hepatol. 22:1995;49-54. (Suppl 2).
9. James J, Bosch KS, Aronson DC, Houtkooper JM. Sirius red histophotometry and spectrophotometry of sections in the assessment of the collagen content of liver tissue and its application in growing rat liver. Liver. 10:1990;1-5.
10. Nakayashi H, Takamatsu S, Nakato H. A simple estimation of liver collagen content by the computed color image analyser using sirius red stained sections. Acta Hepatol Jpn. 34:1993;212-218.
11. Moragas A, Allende H, Sans M, Vidal MT, Garcia-Bonafé M, Huguet P. Cirrhotic changes in livers from children undergoing transplantation. Image analysis. Anal Quant Cytol Histol. 14:1992;359-366.
12. Plebani M, Burlina A. Biochemical markers of hepatic fibrosis. Clin Biochem. 24:1991;219-239.
13. Schuppan D, Stölzel U, Oesterling C, Somasundaram R. Serum assays for liver fibrosis. J Hepatol. 22:1995;82-88. (Suppl.2).
14. Trinchet JC. Clinical use of serum markers of fibrosis in chronic hepatitis. J Hepatol. 22:1995;89-95. (Suppl 2).
15. Junquiera LCU, Bignolas G, Brentani RR. Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections. Histochem J. 11:1979;447-455.
16. Murawaki Y, Ikuta Y, Koda M, Kawasaki H. Serum type III procollagen peptide, type IV collagen 7S domain, central triple-helix of type IV collagen and tissue inhibitor of metal-loproteinases in patients with chronic viral liver disease: relationship to liver histology. Hepatology. 20:1994;780-787.
17. Guéchot J, Poupon RE, Giral P, Balkau B, Giboudeau J, Poupon R. Relationship between procollagen III aminoterminal propeptide and hyaluronan serum levels and histological fibrosis in primary biliary cirrhosis and chronic viral hepatitis C. J Hepatol. 20:1994;388-393.
18. Grimbert S, Trinchet JC, Hartmann DJ, Munz C, Garnier M, Mal F, et al. Comparaison de 6 marqueurs sériques potentiels de la fibrose hépatique au cours de la maladie alcoolique du foie. Gastroenterol Clin Biol. 17:1993;570-577.
19. Bedossa P, Paradis V. Transforming growth factor-β (TGF-β): a key-role in liver fibrogenesis. J Hepatol. 22:1995;37-42. (Suppl. 2).
20. Poynard T, Aubert A, Bedossa P, Abella A, Naveau S, Paraf F, et al. A simple biological index for detection of alcoholic liver disease in drinkers. Gastroenterology. 100:1991;1397-1402.
21. Teare JP, Sherman D, Greenfield SM, Simpson J, Bray G, Catterall AP, et al. Comparison of serum procollagen III peptide concentrations and PGA index for assessment of hepatic fibrosis. Lancet. 342:1993;895-898.
22. Naveau S, Poynard T, Benattar C, Bedossa P, Chaput JC. Alpha-2-macroglobulin and hepatic fibrosis: diagnostic interest. Dig Dis Sci. 11:1994;2426-2432.
23. O'Connel DL, Dobson AJ. General observer-agreement measures on individual subjects and groups of subjects. Biometrics. 40:1984;973-983.
24. James J, Bosch KS, Zuyderhout FMJ, Van Gool J. Histomorphometric estimation of volume density of collagen as an indication of fibrosis in rat liver. Histochemistry. 85:1986;129-133.
25. Puchtler H, Meloan SN, Waldrop FS. Are picro-dye reactions for collagens quantitative? Chemical and histochemical considerations. Histochemistry. 88:1988;243-256.
26. Fort J, Oberti F, Pilette C, Veal N, Gallois Y, Douay O, Calés P. Effects of octreotide on hepatic fibrosis and portal hypertension in the rat [abstract]. Hepatology. 24:1996;320. (Suppl 4 Pt 2).
27. Guerret S, Chevallier M, Chossegros P, Grimaud JA. Comparison of 4 different methods for tissular assessment of collagen content of liver fibrosis in HVC chronic hepatitis and their reliability with sample size. Proceedings of the XVth FECTS Meeting. 1996;. Munich.
28. Manabe N, Chevallier M, Chossegros P, Causse X, Guerret S, Trepo C, et al. Interferon a2b therapy reduces liver fibrosis in chronic non-A, non-B hepatitis: a quantitative histological evaluation. Hepatology. 18:1993;1344-1349.
29. Gibson PR, Fraser JRE, Brown TJ, Finch CF, Jones PA, Colman JC, et al. Hemodynamic and liver function predictors of serum hyaluronan in alcoholic liver disease. Hepatology. 15:1992;1054-1059.
30. Guéchot J, Loria A, Serfaty L, Giral P, Giboudeau J, Poupon R. Serum hyaluronan as a markers of liver fibrosis in chronic viral hepatitis C: effect of alpha interferon therapy. J Hepatol. 22:1995;22-26.
31. Nyberg A, Engström-Laurent, Lars L. Serum hyaluronate in primary biliary cirrhosis: a biochemical marker for progressive liver damage. Hepatology. 8:1988;142-146.
32. Parés A, Deulofeu R, Giménez A, Caballeria L, Bruguera M, Caballeria J, et al. Serum hyaluronate reflects hepatic fibrogenesis in alcoholic liver disease and is useful as a marker of fibrosis. Hepatology. 24:1996;1399-1403.
33. Trinchet JC, Hartmann DJ, Pateron D, et al. Serum type I collagen and N-terminal peptide of type III procollagen in patients with alcoholic liver disease: relationship to liver histology. Alcohol Clin Exp Res. 16:1992;342-346.
34. Capra F, Casaril M, Gabrielli GB, Tognella P, Rizzi A, Dolci L, et al. Alpha-interferon in the treatment of chronic viral hepatitis: effects on fibrogenesis serum markers. J Hepatol. 18:1993;112-118.
35. Oberti F, Valsesia E, Pilette C, Rousselet MC, Bedossa P, Aubé C, et al. Non-invasive diagnosis of hepatic fibrosis or cirrhosis. Gastroenterology. 133:1997;1609-1616.