Localization of gephyrin and glycine receptor subunit immunoreactivity in the rabbit retina

Visual Neuroscience

Volumn 15, Issue 2, 1998, Pages 389-395

  Zucker, Charles L ^a  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

Author keywords

Amacrine cell; GABA; Gephyrin; Glycine receptor; Rabbit retina

Indexed keywords

CARRIER PROTEIN; GEPHYRIN; GLYCINE RECEPTOR; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY;

ANIMAL; ARTICLE; CONFOCAL MICROSCOPY; IMMUNOHISTOCHEMISTRY; METABOLISM; METHODOLOGY; RABBIT; RETINA; STAINING; TISSUE DISTRIBUTION;

ANIMALS; ANTIBODIES, MONOCLONAL; CARRIER PROTEINS; IMMUNOHISTOCHEMISTRY; MEMBRANE PROTEINS; MICROSCOPY, CONFOCAL; RABBITS; RECEPTORS, GLYCINE; RETINA; STAINING AND LABELING; TISSUE DISTRIBUTION;

EID: 0032030687     PISSN: 09525238     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0952523898152173     Document Type: Article

References (47)

1. ALTSCHULER, R.A., BETZ, H., PARAKKAL, M.H., REEKS, K.A. & WENTHOLD, R.J. (1986). Identification of glycinergic synapses in the cochlear nucleus through immunocytochemical localization of the postsynaptic receptor. Brain Research 369, 316-320.
2. APRISON, M.H. & WERMAN, R. (1965). The distribution of glycine in cat spinal cord. Life Science 4, 2075-2083.
3. BETZ, H. (1992). Structure and function of inhibitory glycine receptors. Quarterly Review of Biophysics 25, 381-394.
4. A-receptors at GABAergic synaptic contacts demonstrated by triple immunofluorescence staining. Brain Research 642, 59-69.
5. BOLZ, J., THIER, P., VOIGT, T. & WÄSSLE, H. (1985). Action and localization of glycine and taurine in the cat retina. Journal of Physiology (London) 362, 395-413.
6. Boos, R., SCHNEIDER, H. & WÄSSLE, H. (1993). Voltage- and transmitter-gated currents of all-amacrine cells in a slice preparation of the rat retina. Journal of Neuroscience 13, 2874-2888.
7. CABOT, J.B., BUSHNELL, A., ALESSI, V., MENDELL, N.R., KIRSCH, J. & BETZ, H. (1995). Postsynaptic gephyrin immunoreactivity exhibits a nearly one-to-one correspondence with gamma-aminobutyric acid-like immunogold-labeled synaptic inputs to sympathetic preganglionic neurons. Journal of Comparative Neurology 356, 418-432.
8. CHEN, S. & HILLMAN, D.E. (1993). Colocalization of neurotransmitters in the deep cerebellar nuclei. Journal of Neurocytology 22, 81-91.
9. CHUN, M.H., HAN, S.H., CHUNG, J.W. & WÄSSLE, H. (1993). Electron microscopic analysis of the rod pathway of the rat retina. Journal of Comparative Neurology 332, 421-432.
10. COHEN, E. & STERLING, P. (1986). Accumulation of (3H)glycine by cone bipolar neurons in the cat retina. Journal of Comparative Neurology 250, 1-7.
11. CRAIG, A.M., BANKER, G., CHANG, W., MCGRATH, M.E. & SERPINSKAYA, A.S. (1996). Clustering of gephyrin at GABAergic but not glutamatergic synapses in cultured rat hippocampal neurons Journal of Neuroscience 16, 3166-3177.
12. EHINGER, B. & FALCK, B. (1971). Autoradiography of some suspected neurotransmitter substances: GABA, glycine, aspartic acid, glutamic acid, histamine, dopamine and L-dopa. Brain Research 33, 157-172.
13. ENZ, R. & BORMANN, J. (1995). Expression of glycine receptor subunits and gephyrin in single bipolar cells of the rat retina. Visual Neuroscience 12, 501-507.
14. GRAHAM, D., PFEIFFER, F., SIMLER, R. & BETZ, H. (1985). Purification and characterization of the glycine receptor of pig spinal cord. Biochemistry 24, 990-994.
15. GRÜNERT, U. & WäSSLE, H. (1993). Immunocytochemical localization of glycine receptors in the mammalian retina. Journal of Comparative Neurology 335, 523-537.
16. HENDRICKSON, A.E., KOONTZ, M.A., POURCHO, R.G., SARTHY, P.V. & GOEBEL, D.J. (1988). Localization of glycine-containing neurons in the Macaca monkey retina. Journal of Comparative Neurology 273, 473-487.
17. JÄGER, J. & WÄSSLE, H. (1987). Localization of glycine uptake and receptors in the cat retina. Neuroscience Letters 75, 147-151.
18. JENSEN, R.J. (1991). Involvement of glycinergic neurons in the diminished surround activity of ganglion cells in the dark-adapted rabbit retina. Visual Neuroscience 6, 43-53.
19. KARSCHIN, A. & WÄSSLE, H. (1990). Voltage- and transmitter-gated currents in isolated rod bipolar cells of rat retina. Journal of Neurophysiology 63, 860-876.
20. KIRSCH, J. & BETZ, H. (1993). Widespread expression of gephyrin, a putative glycine receptor tubulin linker protein, in rat brain. Brain Research 621, 301-310.
21. KIRSCH, J., LANOOSCH, D., PRIOR, P., LITTAUER, U. Z., SCHMITT, B. & BETZ, H. (1991). The 93-kDa glycine receptor-associated protein binds to tubulin. Journal of Biological Chemistry 266, 2242-2245.
22. KIRSCH, J., MALOSIO, M.L., WOLTERS, I. & BETZ, H. (1993). Distribution of gephyrin transcripts in the adult and developing rat brain. European Journal of Neuroscicnce 5, 1109-1117.
23. LANGOSCH, D., BECKER, C.M. & BETZ, H. (1990). The inhibitory glycine receptor: A ligand-gated chloride channel of the central nervous system. European Journal of Biochemistry 194, 1-8.
24. LANGOSCH, D., THOMAS, L. & BETZ, H. (1988). Conserved quaternary structure of ligand-gated ion channels: The postsynaptic glycine receptor is a pentamer. Proceedings of the National Academy of Sciences of the U.S.A. 85, 7394-7398.
25. MARC, R.E. (1985), The role of glycine in retinal circuitry. In Retinal Transmitters and Modulators: Models for the Bruin, ed. MORGAN, W. W., pp. 119-158. Boca Raton, Florida: CRC Press.
26. MARC, R.E. (1989). The role of glycine in the mammalian retina. Progress in Retinal Research 8, 67-108.
27. MARC, R.E. & LIU, W.L. (1985). (3H) glycine-accumulating neurons of the human retina. Journal of Comparative Neurology 232, 241-260.
28. MITCHELL, K., SPIKE, R.C. & TODD, A.J. (1993). An immunocytochemical study of glycine receptor and GAB A in laminae-i-III of rat spinal dorsal horn. Journal of Neuroscience 13, 2371-2381.
29. PFEIFFER, F. GRAHAM, D. & BETZ, H. (1982). Purification by affinity chromatography of the glycine receptor of rat spinal cord. Journal of Biological Chemistry 257, 9389-9393.
30. POURCHO, R.G. & GOEBEL, D.J. (1987a). A combined Golgi and auto-radiographic study of 3H-glycine-accumulating cone bipolar cells in the cat retina. Journal of Neuroscience 7, 1178-1188.
31. POURCHO, R.G. & GOEBEL, D.J. (1987b).Visualization of endogenous glycine in cat retina: An immunocytochemical study with fab fragments. Journal of Neuroscience 7, 1189-1197.
32. POURCHO, R.G. & GOEBEL, D.J. (1990). Autoradiographic and immunocytochemical studies of glycine-containing neurons in the retina. In Glycine Neurotransmission, ed. OTTERSEN, O.P. & STORM-MATHISEN, J. pp. 355-390. New York: John Wiley and Sons.
33. POURCHO, R.G. & OWCZARZAK, M.T. (1991a). Connectivity of glycine immunoreactive amacrine cells in the cat retina. Journal of Comparative Neurology 307, 549-561.
34. POURCHO, R.G. & OWCZARZAK, M.T. (1991b). Glycine receptor immunoreactivity is localized at amacrine synapses in cat retina. Visual Neuroscience 7, 611-618.
35. A-receptor subunits in the rat retina. Journal of Comparative Neurology 357, 1-14.
36. SASSOE-POGNETTO, M., WÄSSLE, H. & GRÜNERT, U. (1994). Glycinergic synapses in the rod pathway of the rat retina: Cone bipolar cells express the alpha 1 subunit of the glycine receptor. Journal of Neuroscience 14, 5131-5146.
37. SCHMITT, B., KNAUS, P., BLCKER, C.M. & BETZ, H. (1987). The Mr 93,000 polypeptide of the postsynaptic glycine receptor complex is a peripheral membrane protein. Biochemistry 26, 805-811.
38. SMILEY, J.F. & YAZULLA, S. (1990). Glycinergic contacts in the outer plexiform layer of the Xenopus laevis retina characterized by antibodies to glycine. GABA and glycine receptors. Journal of Comparative Neurology 299, 375-388.
39. SUZUKI, S., TACHIBANA, M. & KANEKO, A. (1990). Effects of glycine and GABA on isolated bipolar cells of the mouse retina. Journal of Physiology 421, 645-662.
40. TAUCK, D.L., FROSCH, M.P., & LIPTON, S.A. (1988). Characterization of GABA- and glycine-induced currents of solitary rodent retinal ganglion cells in culture. Neuroscience 27, 193-203.
41. TRILLER, A., CLUZEAUD, F. & KORN, H. (1987). Gamma-aminobutyric acid-containing terminals can be apposed to glycine receptors at central synapses. Journal of Cell Biology 104, 947-956.
42. TRILLER, A., CLUZEAUD, F., PFEIFFER, F., BETZ, H. & KORN, H. (1985). Distribution of glycine receptors at central synapses: An immunoelectron microscopy study. Journal of Cell Biology 101, 683-688.
43. WASSLE, H., SCHAFER-TRENKLER, I. & VOIGT, T. (1986). Analysis of a glycinergic inhibitory pathway in the cat retina. Journal of Neuroscience 6, 594-604.
44. YAZULLA, S. & STUDHOLME, K.M. (1991a). Glycinergic interplexiform cells make synaptic contact with amacrine cell bodies in goldfish retina. Journal of Comparative Neurology 310, 1-10.
45. YAZULLA, S. & STUDHOLME, K.M. (1991b). Glycine-receptor immunoreactivity in retinal bipolar cells is postsynaptic to glycinergic and GABAergic amacrine cell synapses. Journal of Comparative Neurology 310, 11-20.
46. ZUCKER, CL. & EHINGER, B. (1992). Heterogeneity of receptor immunoreactivity at synapses of glycine-utilizing neurons. Proceedings of the Royal Society B (London) 249, 89-94.
47. ZUCKER, C.L. & EHINGER, B. (1993). Synaptic connections involving immunoreactive glycine receptors in the turtle retina. Visual Neuroscience 10, 907-914.