Role of hydrophobic amino acids in gurmarin, a sweetness-suppressing polypeptide

Biopolymers

Volumn 45, Issue 3, 1998, Pages 231-238

  Ota, Masafumi ^b   Shimizu, Yasutake ^b   Tonosaki, Keiichi ^b   Ariyoshi, Yasuo ^a  

^a AJINOMOTO CO INC   (Japan)

^b GIFU UNIVERSITY   (Japan)

Author keywords

Chorda tympani nerve; Gurmarin; Hydrophobic amino acids; Sweetness suppression; Synthetic peptide

Indexed keywords

AMINO ACIDS; CHEMICAL BONDS; FRUCTOSE; GLUCOSE; MOLECULAR ORIENTATION; PROTEINS; SUGAR (SUCROSE);

GURMARIN; HYDROPHOBIC AMINO ACIDS;

POLYPEPTIDES;

FRUCTOSE; GLUCOSE; GLYCOGEN; GURMARIN; POLYPEPTIDE; SUCROSE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; HYDROPHOBICITY; NUCLEAR MAGNETIC RESONANCE; PROTEIN ANALYSIS; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; DISULFIDES; DRUG INTERACTIONS; GLUTAMINE; GLYCINE; ISOLEUCINE; LEUCINE; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MOLECULAR SEQUENCE DATA; PLANT PROTEINS; PROLINE; RATS; RATS, WISTAR; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SWEETENING AGENTS; TASTE; TRYPTOPHAN; TYROSINE;

CHORDA; GYMNEMA SYLVESTRE;

EID: 0032030549     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-0282(199803)45:3<231::aid-bip5>3.0.co;2-s     Document Type: Article

References (12)

1. Imoto, T., Miyasaka, A., Ishima, R. & Akasaka, K. (1991) Comp. Biochem. Physiol 100A, 309-314.
2. Yoshie, S., Miyasaka, A. & Imoto, T. (1994) Arch. Histol. Cytol. 57, 531-534.
3. Miyasaka, A. & Imoto, T. (1995) Brain Res. 676, 63-68.
4. Ninomiya, Y. & Imoto, T. (1995) Am. J. Physiol. Regul. Integr. Comp. Physiol 37, R1019-R1025.
5. Tonosaki, K. & Funakoshi, M. (1989) Comp. Biochem. Physiol. 92A, 181-183.
6. Kamei, K., Takano, R., Miyasaka, A., Imoto, T. & Hara, S. (1992) J. Biochem. 111, 109-112.
7. Ota, M. & Ariyoshi, Y. (1995) Biosci. Biotech. Biochem. 59, 1956-1957.
8. Arai, K., Ishima, R., Morikawa, S., Miyasaka, A., Imoto, T., Yoshimura, S., Aimoto, S. & Akasaka, K. (1995) J. Biomol. NMR 5, 297-305.
9. Ota, M., Tonosaki, K., Miwa, K., Fukuwatari, T. & Ariyoshi, Y. (1996) Biopolymers 39, 199-205.
10. Wade, D., Boman, A., Wåhlin, B., Drain, C. M., Andreu, D., Boman, H. G. & Merrifield, R. B. (1990) Proc. Natl. Acad. Sci. USA 87, 4761-4765.
11. Fields, C. G., Lloyd, D. H., Macdonald, R. L., Otteson K. M. & Noble, R. L. (1991) Pept. Res. 4, 95-101.
12. Kubo, S., Chino, N., Kimura, T. & Sakakibara, S. (1995) in Peptide Chemistry 1994, Ohno, M., Ed., Protein Research Foundation, Osaka, pp. 313-316.