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Volumn 16, Issue 3-5, 1998, Pages 399-431

Optimal control of the primary and secondary drying stages of bulk solution freeze drying in trays

Author keywords

[No Author keywords available]

Indexed keywords

DRUG PRODUCTS; DRYERS (EQUIPMENT); MATHEMATICAL MODELS; OPTIMIZATION; PRESSURE; PROBLEM SOLVING; PROCESS CONTROL; TEMPERATURE; VARIATIONAL TECHNIQUES;

EID: 0032030095     PISSN: 07373937     EISSN: None     Source Type: Journal    
DOI: 10.1080/07373939808917417     Document Type: Article
Times cited : (73)

References (18)
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    • Litchfield, R.J.1    Liapis, A.I.2
  • 2
    • 0022145196 scopus 로고
    • An analysis of the lyophilization process using a sorption-sublimation model and various operational policies
    • Millman, M. J., Liapis, A. I., and Marchello, J. M., 1985, An analysis of the lyophilization process using a sorption-sublimation model and various operational policies", AIChE J., 31, pp. 1594-1604.
    • (1985) AIChE J. , vol.31 , pp. 1594-1604
    • Millman, M.J.1    Liapis, A.I.2    Marchello, J.M.3
  • 3
    • 0041894519 scopus 로고
    • A multidimensional model describing the lyophilization of a pharmaceutical product in a vial
    • A. S. Mujumdar(ed), Hemisphere Publishing Corporation, New York, New York, U.S.A.
    • Tang, M. M., Liapis, A. I., and Marchello, J. M., 1986, " A multidimensional model describing the lyophilization of a pharmaceutical product in a vial", in Proceedings of the Fifth International Drying Symposium, Vol 1, A. S. Mujumdar(ed), Hemisphere Publishing Corporation, New York, New York, U.S.A., pp. 57-65.
    • (1986) Proceedings of the Fifth International Drying Symposium , vol.1 , pp. 57-65
    • Tang, M.M.1    Liapis, A.I.2    Marchello, J.M.3
  • 4
    • 0026107089 scopus 로고
    • Experimentation and modelling of pharmaceutical lyophilization using a pilot plant"
    • Bruttini, R., Rovero, G., and Baldi, G., 1991, "Experimentation and modelling of pharmaceutical lyophilization using a pilot plant", Chemical Engineering Journal, 45. pp. B67-B77.
    • (1991) Chemical Engineering Journal , vol.45
    • Bruttini, R.1    Rovero, G.2    Baldi, G.3
  • 5
    • 0028464717 scopus 로고
    • A theory for the primary and secondary drying stages of the freeze-drying of pharmaceutical crystalline and amorphous solutes: Comparison between experimental data and theory
    • Liapis, A. I., and Bruttini, R., 1994, "A theory for the primary and secondary drying stages of the freeze-drying of pharmaceutical crystalline and amorphous solutes: Comparison between experimental data and theory", Separations Technology, 4, pp. 144-155.
    • (1994) Separations Technology , vol.4 , pp. 144-155
    • Liapis, A.I.1    Bruttini, R.2
  • 6
    • 0002658555 scopus 로고
    • Freeze Drying"
    • A. S. Mujumdar (ed), Marcel Dekker, Inc. New York and Basel
    • Liapis, A. I., and Bruttini, R., 1995, "Freeze Drying", in "Handbook of Industrial Drying" (Second Edition), A. S. Mujumdar (ed), Marcel Dekker, Inc. New York and Basel, pp. 309-343.
    • (1995) Handbook of Industrial Drying (Second Edition) , pp. 309-343
    • Liapis, A.I.1    Bruttini, R.2
  • 7
    • 0002515660 scopus 로고
    • Freeze-drying of pharmaceutical crystalline and amorphous solutes in vials: Dynamic multi-dimensional models of the primary and secondary drying stages and qualitative features of the moving interface
    • Liapis, A. I., and Bruttini, R., 1995, "Freeze-drying of pharmaceutical crystalline and amorphous solutes in vials: Dynamic multi-dimensional models of the primary and secondary drying stages and qualitative features of the moving interface", Drying Technology, 13. pp. 43-72.
    • (1995) Drying Technology , vol.13 , pp. 43-72
    • Liapis, A.I.1    Bruttini, R.2
  • 8
    • 0030190595 scopus 로고    scopus 로고
    • Research and development needs and opportunities in freeze drying
    • Liapis, A. L, Pikal, M. J., and Bruttini, R., 1996, "Research and development needs and opportunities in freeze drying", Drying Technology, 14, pp. 1265-1300.
    • (1996) Drying Technology , vol.14 , pp. 1265-1300
    • Liapis, A.L.1    Pikal, M.J.2    Bruttini, R.3
  • 9
    • 0031102433 scopus 로고    scopus 로고
    • Mathematical modelling of the primary and secondary drying stages of bulk solution freeze drying in trays: Parameter estimation and model discrimination by comparison of theoretical results with experimental data
    • Sadikoglu, H., and Liapis, A. I., 1997, "Mathematical modelling of the primary and secondary drying stages of bulk solution freeze drying in trays: Parameter estimation and model discrimination by comparison of theoretical results with experimental data," Drying Technology, 15. pp.791810.
    • (1997) Drying Technology , vol.15 , pp. 791810
    • Sadikoglu, H.1    Liapis, A.I.2
  • 11
    • 0018701872 scopus 로고
    • Optimal control of a freeze dryer I: Theoretical development and quasi steady state analysis
    • Liapis, A. I., and Litchfield, R. J., 1979, "Optimal control of a freeze dryer I: Theoretical development and quasi steady state analysis", Chemical Engineering Science, 34. pp. 975-981.
    • (1979) Chemical Engineering Science , vol.34 , pp. 975-981
    • Liapis, A.I.1    Litchfield, R.J.2
  • 12
    • 0019924807 scopus 로고
    • Optimal control of a freeze dryer II: Dynamic analysis
    • Litchfield, R. J., and Liapis, A. I., 1982, "Optimal control of a freeze dryer II: Dynamic analysis", Chemical Engineering Science, 37. pp. 45-55.
    • (1982) Chemical Engineering Science , vol.37 , pp. 45-55
    • Litchfield, R.J.1    Liapis, A.I.2
  • 16
    • 0018651063 scopus 로고
    • Numerical solution of moving boundary transport problems in finite media by orthogonal collocation
    • Liapis, A. I., and Litchfield, R. J., 1979, "Numerical solution of moving boundary transport problems in finite media by orthogonal collocation", Computers in Chemical Engineering, 3_, pp. 615-621.
    • (1979) Computers in Chemical Engineering , vol.3 , pp. 615-621
    • Liapis, A.I.1    Litchfield, R.J.2
  • 18
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    • The secondary drying stage of freeze drying: Drying kinetics as a function of temperature and chamber pressure
    • Pikal, M.J., Shah, S., Roy, M.L., and Putman, R., 1990, "The secondary drying stage of freeze drying: Drying kinetics as a function of temperature and chamber pressure", Int. J. Pharmaceut., 60. pp. 203-217.
    • (1990) Int. J. Pharmaceut. , vol.60 , pp. 203-217
    • Pikal, M.J.1    Shah, S.2    Roy, M.L.3    Putman, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.