Salt taste responses of the IXth nerve in Sprague-Dawley rats: Lack of sensitivity to amiloride

Physiology and Behavior

Volumn 63, Issue 5, 1998, Pages 945-949

  Kitada, Yasuyuki ^a   Mitoh, Yoshihiro ^a   Hill, David L ^b  

^a OKAYAMA UNIVERSITY   (Japan)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Amiloride; Anion; Electrophysiology; Glossopharyngeal nerve; Salt; SD rats; Taste

Indexed keywords

AMILORIDE; SODIUM CHLORIDE;

ARTICLE; CHORDA TYMPANI; ELECTROPHYSIOLOGY; GLOSSOPHARYNGEAL NERVE; NEUROPHYSIOLOGY; NONHUMAN; PRIORITY JOURNAL; RAT; TASTE; TASTE BUD;

EID: 0032029969     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9384(98)00009-2     Document Type: Article

References (32)

1. Beidler L. M. A theory of taste stimulation. J. Gen. Physiol. 38:1954;133-139.
2. Beidler L. M. Anion influences on taste receptor response. Hayashi T. Olfaction and taste II. 1967;509-534 Pergamon Press, New York.
3. Boudreau J. C., Do L. T., Sivakumar L., Oravec J., Rodriguez C. A. Taste systems of the petrosal ganglion of the rat glossopharyngeal nerve. Chem. Senses. 12:1987;437-458.
4. Brand J. G., Teeter J. H., Silver W. L. Inhibition by amiloride of chorda tympani responses evoked by monovalent salts. Brain Res. 334:1985;207-214.
5. DeSimone J. A., Ferrell F. Analysis of amiloride inhibition of chorda tympani taste response of rat to NaCl. Am. J. Physiol. 249:1985;R52-R61.
6. DeSimone J. A., Heck G. L., Mierson S., DeSimone S. K. The active ion transport properties of canine lingual epithelia in vitro. J. Gen. Physiol. 83:1984;633-656.
7. Doolin R. E., Gilbertson T. A. Distribution and characterization of functional amiloride-sensitive sodium channels in rat tongue. J. Gen. Physiol. 107:1996;545-554.
8. Elliott E. J., Simon S. A. The anion in salt taste: A possible role for paracellular pathways. Brain Res. 535:1990;9-17.
9. Formaker B. K., Hill D. L. An analysis of the residual NaCl taste response following amiloride. Am. J. Physiol. 225:1988;R1002-R1007.
10. Formaker B. K., Hill D. L. Lack of amiloride sensitivity in SHR and WKY glossopharyngeal taste responses to NaCl. Physiol. Behav. 50:1991;765-769.
11. Frank M. E. Taste-responsive neurons of the glossopharyngeal nerve of the rat. J. Neurophysiol. 65:1991;1452-1463.
12. Green B. G., Gelhard B. Salt as an oral irritant. Chem. Senses. 14:1989;259-271.
13. Hanamori T., Miller I. J. Jr, Smith D. V. Gustatory responsiveness of fibers in the hamster glossopharyngeal nerve. J. Neurophysiol. 60:1988;478-498.
14. Heck G. L., Mierson S., DeSimone J. A. Salt taste transduction occurs through an amiloride-sensitive sodium transport pathway. Science. 223:1984;403-405.
15. Hettinger T. P., Frank M. E. Specificity of amiloride inhibition of hamster taste responses. Brain Res. 513:1990;24-34.
16. Hill D. L., Bour T. C. Addition of functional amiloride-sensitive components to the receptor membrane: A possible mechanism for altered taste responses during development. Dev. Brain Res. 20:1985;310-313.
17. Kinnamon S. C., Cummings T. A. Chemosensory transduction mechanism in taste. Annu. Rev. Physiol. 54:1992;715-731.
18. Kitada Y. Anions modulate cation-induced responses of single units of the frog glossopharyngeal nerve. Brain Res. 694:1995;253-263.
19. 4 salt taste transduction. J. Neurophysiol. 77:1997;1393-1406.
20. Ninomiya Y., Funakoshi M. Amiloride inhibition of responses of rat single chorda tympani fibers to chemical and electrical tongue stimulations. Brain Res. 45:1988;319-325.
21. Ninomiya Y., Tanimukai T., Yoshida S., Funakoshi M. Gustatory neural responses in preweanling mice. Physiol. Behav. 49:1991;913-918.
22. Oakley B., Jones L. B., Kaliszewski J. M. Taste responses of the gerbil IX nerve. Chem. Senses Flavour. 4:1979;79-87.
23. Ogawa H. Taste response characteristics in the glossopharyngeal nerve of the rat. Kumamoto Med. J. 25:1972;137-147.
24. Rehnberg B. G., Mackinnon B. I., Hettinger T. P., Frank M. E. Anion modulation of taste responses in sodium-sensitive neurons of the hamster chorda tympani nerve. J. Gen. Physiol. 101:1993;453-465.
25. Shingai T., Beidler L. M. Response characeristics of three taste nerves in mice. Brain Res. 335:1985;245-249.
26. Sostman A. L., Simon S. A. Trigeminal nerve responses in the rat elicited by chemical stimulation of the tongue. Arch. Oral Biol. 36:1991;95-102.
27. Wang Y., Erickson R. P., Simon S. A. Selectivity of lingual nerve fibers to chemical stimuli. J. Gen. Physiol. 101:1993;843-866.
28. Weast, R. C., ed. Handbook of chemistry and physics, 50th ed. Cleveland: The Chemical Rubber Company; 1969-1970:D-121.
29. Yamada K. Gustatory and thermal responses in the glossopharyngeal nerve of the rat. Jpn. J. Physiol. 16:1966;599-611.
30. Ye Q., Heck G. L., DeSimone J. A. The anion paradox in sodium taste reception: Resolution by voltage-clamp studies. Science. 254:1991;724-726.
31. + salts: Implications for the functional organization of taste receptor cells. J. Neurophysiol. 70:1993;167-178.
32. + salts in the rat: Implications for gustatory transduction. J. Gen. Physiol. 104:1994;885-907.