A PCR-based diagnostic test for fucosidosis in English Springer Spaniels

Veterinary Journal

Volumn 155, Issue 2, 1998, Pages 113-114

  Holmes, N G ^a   Acheson, T ^a   Ryder, E J ^a   Binns, M M ^a  

^a ANIMAL HEALTH TRUST   (United Kingdom)

Author keywords

DNA test; Fucosidosis; Polymerase chain reaction

Indexed keywords

ALPHA LEVO FUCOSIDASE; PRIMER DNA;

ANIMAL; ANIMAL DISEASE; ARTICLE; DOG; DOG DISEASE; EXON; FUCOSIDOSIS; GENETICS; HETEROZYGOTE DETECTION; METHODOLOGY; POLYMERASE CHAIN REACTION;

ALPHA-L-FUCOSIDASE; ANIMALS; DNA PRIMERS; DOG DISEASES; DOGS; EXONS; FUCOSIDOSIS; HETEROZYGOTE DETECTION; POLYMERASE CHAIN REACTION;

EID: 0032019959     PISSN: 10900233     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1090-0233(98)80001-4     Document Type: Article

References (6)

1. BARKER, C. G., HERRTAGE, M. E., SHANAHAN, F. & WINCHESTER, B. G. (1988). Fucosidosis in English springer spaniels: results of a trial screening programme. Journal of Small Animal Practice 29, 623-630.
2. DUTTON, C. M., PAYNTON, C. & SOMMER, S. S. (1993). General method for amplifying regions of very high G+C content. Nucleic Acids Research. 21, 2953-2954.
3. HEALY, P. J., FARROW, B. R. H., NICHOLAS, F. W., HEDBERG, K., RATCLIFFE, R. (1984). Canine fucosidosis: a biochemical and genetic investigation. Research in Veterinary Science 36, 354-359.
4. KELLY, W. R., CLAGUE, A. E., BARNS, R. J., BATE, M. J. & MACKAY, B. M. (1983). Canine α-L-Fucosidosis: A storage disease of springer spaniels. Acta Neuropathologica (Berl) 60, 9-13.
5. OCCHIODORO, T. & ANSON, D. S. (1996). Isolation of the canine α-L-fucosidase cDNA and definition of the fucosidosis mutation in English Springer Spaniels. Mammalian Genome 7, 271-274.
6. SKELLY, B. J., SARGAN, D. R., HERRTAGE, M. E. & WINCHESTER, B. G. (1996). The molecular defect underlying canine fucosidosis. Journal of Medical Genetics 33, 284-288.