Long-term effects of pesticides on health: Review of current epidemilogic knowledge;Effects retardes des pesticides sur la sante: Etat des connaissances epidemiologiques

Revue d'Epidemiologie et de Sante Publique

Volumn 46, Issue 2, 1998, Pages 134-142

  Baldi, I ^a   Mohammed Brahim, B ^a   Brochard, P ^a   Dartigues, J F ^b   Salamon, R ^b  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b INSERM   (France)

Author keywords

Environment; Long term epidimiology; Pesticides

Indexed keywords

PESTICIDE;

AGRICULTURE; BIRTH DEFECT; DISEASE ASSOCIATION; HEMATOLOGIC DISEASE; HUMAN; INFERTILITY; MALIGNANT NEOPLASTIC DISEASE; NEUROTOXICITY; PARKINSON DISEASE; PERINATAL MORTALITY; POLYNEUROPATHY; PREGNANCY COMPLICATION; REVIEW; CHEMICALLY INDUCED DISORDER; ENVIRONMENTAL EXPOSURE; EPIDEMIOLOGY; FEMALE; HEALTH STATUS; METHODOLOGY; NEOPLASM; NEUROLOGIC DISEASE; PREGNANCY; REPRODUCTION; RETROSPECTIVE STUDY;

ENVIRONMENTAL EXPOSURE; EPIDEMIOLOGIC METHODS; FEMALE; HEALTH STATUS; HUMANS; NEOPLASMS; NERVOUS SYSTEM DISEASES; PESTICIDES; PREGNANCY; REPRODUCTION; RESEARCH DESIGN; RETROSPECTIVE STUDIES;

EID: 0032019258     PISSN: 03987620     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (106)

1. Journal Officiel des Communautés Européennes du 15/7/1991. Directive du Conseil concernant la mise sur le marché des produits phyto-pharmaceutiques (91/414: CEE).
2. Büchel KH. Political, economic and philosophical aspects of pesticide use for human welfare. Regul Toxicol Pharmacol 1984 ; 4 : 174-91.
3. Hascoet M, Bourdin J. Évolution des produits anti-parasitaires et situation actuelle. Phytoma 1988 ; 400 : 68-73.
4. Easter EP, Nigg HN. Pesticide protective clothing. Rev Environ Contam Toxicol 1992 ; 129 : 1-16.
5. Larguier M, Michon P. Un aperçu de l'évolution des produits sanitaires. Bulletin Technique d'Information du Ministère de l'Agriculture et de la Pêche 1994 ; 17 : 12-21.
6. World Health Organization. Safe use of pesticides - 20th report. Geneva, 1973.
7. Levine RS, Doull J. Global estimates of acute pesticide morbidity and mortality. Rev Environ Contam Toxicol 1992 ; 129 : 29-50.
8. El Sebae AH. Special problems experienced with pesticide use in developing countries. Regul Toxicol Pharmacol 1993 ; 17 : 287-91.
9. Jeyaratnam J. Acute pesticide poisoning : a major global health problem. Wld Hlth Statis Quart 1990 ; 43 : 139-44.
10. Delemotte B, Foulhoux P, Nguyen SN, Fages J, Portos JL. Le risque pesticide en agriculture. Arch Mal Prof 1987 ; 48 : 467-75.
11. Rappe A. Pesticides et santé. Bruxelles : Association Pharmaceutique Belge, 1992.
12. Steenland K, Jenkins B, Ames RG. Chronic neurological sequelae to organophosphate pesticide poisoning. Am J Public Health 1994 ; 84 : 731-6.
13. Sharp DS, Eskenazy B. Delayed health hazards of pesticide exposure. Ann Rev Public Health 1986 ; 7 : 441-71.
14. Moses M. Pesticide-related health problems and farmworks. AAOHN 1989 ; 37 : 115-30.
15. Maroni M, Fait A. Health effects in man from long-term exposure to pesticides. A review of the 1975-1991 literature. Toxicology 1993 ; 78 : 1-180.
16. Burmeister LF, Everett GD, Van Lier SF, Isacson P. Selected cancer mortality and farm practice in Iowa. Am J Epidemiol 1983 ; 118 : 72-7.
17. Burmeister LF. Cancer mortality in Iowa framers, 1971 - 1978. JNCI 1981 ; 66 : 461-4.
18. Delzell E, Grufferman S. Mortality among white and nonwhite farmers in North Carolina, 1976-1978. Am J Epidemiol 1985 ; 121 : 391-402.
19. Kristensen P, Andersen A, Irgens LM, Laak P, Bye AS. Incidence and risk factors of cancer among men and women in Norwegian agriculture. Scand J Work Environ Health 1996 ; 22 : 41-26.
20. Fingerhut MA, Halperin WE, Marlow DA et al. Cancer mortality in workers exposed to 2,3-7,8 tetrachlorodibenzo-p-dioxin. N Eng J Med 1991 ; 324 : 212-8.
21. Flesch-Janys D, Berger J, Gurn P et al. Exposure to polychlorinated dioxins and furans (PCDD/F) and mortality in a cohort of workers from a herbicide-producing plant in Hamburg, Federal Republic of Germany. Am J Epidemiol 1995 ; 142: 1165-75.
22. Manz A, Berger J, Dwyer JH, Flesch-Janys D, Nagel S, Waltsgott H. Cancer mortality among workers in chemical plant contaminated with dioxin. Lancet 1991 ; 338 : 959-64.
23. Saracci R, Kogevinas M, Bertazzi PA et al. Cancer mortality in workers exposed to chlorophenoxy herbicides and chlorophenols. Lancet 1991 ; 338 : 1027-32.
24. Figa-Talamanca I, Mearelli I, Valente P. Mortality in a cohort of pesticide applicators in an urban setting. Int J Epidemiol 1993 ; 22 : 674-6.
25. Thomas HF, Winter PD, Donaldson LJ. Cancer mortality among local autority pest control officers in England and Wales. Occup Environ Med 1996 ; 53 : 787-90.
26. Zhong Y, Rafnsson V. Cancer among icelandic pesticide users. Int J Epidemiol 1996 ; 25 : 1117-24.
27. Blair A, Thomas TL. Leukemia among Nebraska farmers : a death certificat study. Am J Epidemiol 1979 ; 110 : 264-73.
28. Hardell L, Bengtsson NO. Epidemiological study of socioeconomic factors and clinical findings in Hodgkin's disease, and reanalysis of previous data regarding chemical exposure. Br J Cancer 1983 ; 48 : 217-25.
29. Hoar SK, Blair AA, Holmes FF. Agricultural herbicide use and risk of lymphoma and soft tissue sarcoma. JAMA 1986 ; 256 : 1141-7.
30. Cantor K, Everett G, Blair A. Farming and non-Hodgkin's lymphoma. Am J Epidemiol 1985 ; 122 : 535.
31. Reif J, Pearce N, Kawachi I, Fraser J. Soft-tissue sarcoma, non-hodgkin's lymphoma and other cancers in New Zealand forestry workers. Int J Cancer 1989 ; 49-54.
32. Nanni O, Amadori D, Lugaresi C et al. Chronic lymphocytic leukaemias and non-Hodgkin's lymphomas by histological type in farming-animal breeding workers : a population case-control study based on a priori exposure matrices. Occup Environ Med 1996 ; 53 : 652-7.
33. Hoar SK, Zahm SH, Blair A. Pesticides and non-Hodgkin's lymphoma. Cancer Res 1992 ; 52 : 5485s-8s.
34. Pearce NE, Sheppard RA, Howard JK, Fraser J, Lilley BM. Leukemia among New Zealand agricultural workers. Am J Epidemiol 1986 ; 124 : 402-9.
35. Brown LM, Blair A, Gibson R et al. Pesticides exposures and other agricultural risk factors for leukemia among men in Iowa and Minnesota. Cancer Res 1990 ; 50:6585-91.
36. Clavel J, Hémon D., Mandereau L, Delemotte B, Severin F, Flandrin G. Farming, pesticide use and hairy-cell leukemia. Scand J Work Environ Health 1996 ; 22 : 285-93.
37. Boffetta P, Stellman SD, Garfinkel L. A case-control study of multiple myeloma nested in the American Cancer Society prospective study. Int J Cancer 1989 ; 43 : 554-9.
38. Demers PA, Vaughan TL, Loepsell TD et al. A case-control study of multiple myeloma and occupation. An J Indus Med 1993 ; 23 : 629-39.
39. Hardell L, Eriksson M. The association between soft tissue sarcomas and exposure to phenoxyacetic acides. Cancer 1988 ; 62 : 652-6.
40. Eriksson M, Hardell L, Berg NO, Möller T, Axelson O. Soft-tissue sarcomas and exposure to chemical substances : a case-referent study. Br J Ind Med 1981 ; 38 : 27-33.
41. Hardell L, Eriksson M, Degermen A. Meta-analysis of four Swedish case-control studies on exposure to pesticides as risk-factor for soft-tissue sarcoma including the relation to tumour localization and histopathological type. Int J Oncol 1995 ; 6 : 847-51.
42. Woods JS, Polissar L, Severson RK, Heuser LS, Kulander BG. Soft-tissue sarcoma and non-hodgkin's lymphoma in relation to phenoxyherbicide and chlorinated phenol exposure in western Washington. J Natl Cancer Inst 1987 ; 78 : 899-910.
43. Morrison HI, Semenciw RM, Morison D, Magwood S, Mao Y. Brain cancer and farming in western Canada. Neuroepidemiology 1992 ; 11 : 267-76.
44. Mussico M, Sant M, Molinari S, Filippini G, Gatta G, Berrino F. A case-control study of brain gliomas and occupational exposure to chemical carcinogens : the risk to farmers. Am J Epidemiol 1988 ; 128 : 778-85.
45. Ferrari G, Lovaste MG. Primary intracranial tumors in the Province of Trento - Italy (1977-1984). Neuroepidemiol 1986 ; 5 : 159-70.
46. Rodvall Y, Ahlbom A, Spannare BGN. Glioma and occupational exposure in Sweden. Occup Environ Med 1996 ; 53 : 526-37.
47. Vineis P, Thomas T, Hayes RB et al. Proportion of lung cancers in males, due to occupation, in different areas of the USA. Int J Cancer 1988 ; 452 : 851-2.
48. Pesatori AC, Sontag JM, Lubin JH, Consonni D, Blair A. Cohort mortality and nested case-control study of lung cancer among structural pest control workers in Florida (United States). Cancer Causes and Control 1994 ; 5 : 310-8.
49. Wilkinson P, Thakrar B, Shaddick G et al. Cancer incidence and mortality around the Pan britannica Industries pesticides factory. Occup Environ Med 1997 ; 54 : 101-7.
50. Morrison H SD, Semenciw R, Hulka B, Mao Y, Morrison D, Wigle D. Farming and prostate cancer mortality. Am J Epidemiol 1993 ; 137 : 270-80.
51. Mills PK, Newell GR, Johnson DE. Testicular cancer associated with employment in agriculture and oil and natural gas extraction. Lancet 1984 ; 1 : 207-10.
52. Donna A, Betta PG, Robutti F, Crosignani P, Berrino F, Bellingeri D. Ovarian mesothelial tumors and herbicides : a case-control study. Carcinogenesis 1984 ; 5 : 941-2.
53. Falck F, Ricci A, Wolff MS, Godbold J, Deckers P. Pesticides and polychlorinated biphenyl residues in human breast lipids and their relation to breast cancer. Arch Environ Health 1992 ; 47 : 143-6.
54. Key T, Reeves G. Organochlorines in the environment and breast cancer. Br Med J 1994 ; 308 : 1520-1.
55. Figa-Talamanca I, Mearelli I, Valente P, Bascherini S. Cancer mortality in a cohort of rural licensed pesticide users in the province of Rome. Int J Epidemiol 1993 ; 22 : 579-83.
56. Meinert R, Kaatsch P, Kaletsch U, Krummenauer F, Miesner A, Michaelis J. Childhood leukaemia and exposure to pesticides : results of a case-control study in northern Germany. Eur J Cancer 1996 ; 32A : 1943-8.
57. Kristensen P, Andersen A, Irgens LM, Bye AS, Sundheim L. Cancer in offspring of parents engaged in agricultural activities in Norway : incidence and risk factors in the farm environment. Int J Cancer 1996 ; 65 : 39-50.
58. Rowland S. Pesticides and birth defects. Epidemiology 1995 ; 6 : 6-7.
59. Egeland GM, Sweeney MH, Fingerhut MA, Will KK, Schnorr TM, Halperin WE. Total serum testosterone and gonadotropins in workers exposed to dioxin. Am J Epidemiol 1994 ; 139 : 272-81.
60. Rita P, Reddy PP, Venkatram Reddy S. Monitoring of workers occupationaly exposed to pesticides in grape gardens of Andhra Pradesh. Environ Res 1987 ; 44 : 1-5.
61. Taha TE, Gray RH. Agricultural pesticide exposure and perinatal mortality in central Sudan. Bull World Health Organ 1993 ; 71 : 317-21.
62. Munger R, Isacson P, Hu S et al. Intrauterine growth retardation in Iowa communities with herbicide-contaminated drinking water supplies. Environ Health Perspect 1997 ; 5 : 308-14.
63. Balarajan R. Congenital malformations and agricultural workers. Lancet 1983 ; 1 : 1112-3.
64. Brogan WF, Brogan CE, Dadd JT. Herbicides and cleft lip and palate [letter]. Lancet 1980 ; i : 597.
65. Nurminen T, Rantala K, Kurppa K, Holmberg PC. Agricultural work during pregnancy and selected structural malformations in Finland. Epidemiology 1995 ; 6 : 23-30.
66. Aschengrau A, Monson RR. Paternal military service in Vietnam and the risk of late adverse pregnancy outcomes. Am J Public Health 1990 ; 80 : 1218-24.
67. Sharpe CR, Franco EL, De Camargo B. Parental exposures to pesticides and risk of Wilm's tumor in Brazil. Am J Epidemiol 1995 ; 141 : 210-7.
68. Lindbohm ML. Paternal TCDD exposure and pregnancy outcome. Epidemiology 1995 ; 6 : 4-6.
69. Schnitzer PG, Olshan AF, Frickson JD. Paternal occupation and risk of birth defects in offspring. Epidemiology 1995 ; 6 : 577-83.
70. Boyle CA, Decouflé P, O'Brien TR. Long-term health consequences of military service in Vietnam. Epidemiol Rev 1989 ; 11 : 1-27.
71. Coggon D, Acheson ED. Do phenoxy herbicides cause cancer in man ? Lancet 1982 : 1057-9.
72. La Vecchio FA, Pashayan HM, Singer W. Agent Orange and birth defects [letter]. New Eng J Med 1983 ; 308 : 719-20.
73. Levallois P, Ayotte P. Cancer incidence and dioxin exposure [letter]. Epidemiology 1995 ; 6 : 197-8.
74. Senanayake N, Karalliedde L. Neurotoxic effects of organophosphorus insecticides. An intermediate syndrome. New Eng J Med 1987 ; 316 ; 761-3.
75. Senanayake N. Polyneuropathy following insecticide poisoning. A clinical and electrophysiological study [abstract]. J Neuro 1985 ; 232 : S203.
76. Stokes L, Stark A, Marshall E, Narang A. Neurotoxicity among pesticides applicators exposed to organophosphates. Occup Environ Med 1995 ; 52 : 648-53.
77. Ruitjen MW, Sallé HJ, Verbek MM, Smink M. Effect of chronic mixed pesticide exposure on peripheral and autonomic nerve function. Arch Environ Health 1994 ; 49 : 188-95.
78. Hogstedt C, Lundberg I. Epidemiology of occupational neurobehavioural hazards. Methodological experiences from organic solvent research. Rev Epidemiol Santé Publique 1992 ; 40 : S7-16.
79. Izmerov N, Tarasova L. Occupational diseases developed as a result of severely injured nervous system : acute and chronic neurotic effects. Environ Res 1993 ; 62 : 127-7.
80. Savage EP, Keefe TJ, Mounce LM, Heaton RK. Lewis JA, Burcar PJ. Chronic neurological sequelae of acute organophosphate pesticide poisoning. Arch Environ Health 1988 ; 43 : 38-45.
81. Parron T, Hernandez AF, Villanueva E. Increased risk of suicide with exposure to pesticides in an intensive agriculture area. A 12-year retrospective study. Forensic Sci Int 1996 ; 79 : 53-63.
82. Jonkman FJ, De Weerd AW, Poortvliet DCJ, Veldhuizen RJ, Emmen H. Electroencephalographic studies in workers exposed to solvent or pesticides. Electroencephalogr Clin Neurophysiol 1992 ; 82 : 438-44.
83. Heuser G, Mena I, Alamos F. Neurospect findings in patients exposed to neurotoxic chemicals. Toxicol Ind Health 1994 ; 10 : 561-71.
84. Eyer P. Neuropsychopathological changes by organophosphorus compounds - a review. Hum Exp Toxicol 1995 ; 14 : 857-64.
85. Zuber M, Alpérovitch A. Maladie de Parkinson et facteurs environnementaux. Rev Epidemiol Santé Publique 1991 ; 39 : 373-87.
86. Bocchetta A, Corsini GU. Parkinson's disease and pesticides. Lancet 1986 ; i : 1163.
87. Sechi GP AV, Piredda M, Canu M, Desserra F, Omar HA, Rosati G. Acute and persistent parkinsonism after use of diquat. Neurology 1992 ; 42 : 261.
88. Barbeau A, Roy M, Bernier G, Campanella G, Paris S. Ecogenetics of Parkinson's disease : prevalence and environmental aspects in rural areas. Can J Neurol Sci 1987 ; 14 : 36-41.
89. Goldsmith JR, Herishanu Y, Abarbanel JM, Weinbaum Z. Clustering of Parkinson's disease points to environmental etiology. Arch Envir Health 1990 ; 45 : 88-94.
90. Hubble JP, Cao T, Hassanein JS, Neuberer JS, Koller WC. Risk factors for Parkinson's disease. Neurology 1993 ; 43 : 1693-7.
91. Jimenez-Jimenez FJ, Mateo D, Gimenez-Roldan S. Exposure to well-water and pesticides in Parkinson's disease : a case-control study in the Madrid area. Mov Dis 1992 ; 7 : 149-52.
92. Morano AJ-JF, Molina JA, Antolin MA. Risk factors for Parkinson's disease : case-control study in the province of Caceres. Acta Neurol Scand 1994 ; 89 : 164-70.
93. Hertzman C, Wiens M, Bowering D, Snow B, Calne D. Parkinson's disease : a case-control study of occupational and environmental risk factors Am J Ind Med 1990 ; 17 : 349-55.
94. Ho SC, Woo J, Ming Lee C. Epidemiology study of Parkinson's disease in Hong Kong. Neurology 1989 ; 39 : 1314-8.
95. Butterfield PG, Valanis BG, Spencer PS, Linderman CA, Nutt JG. Environmental antecedents of young-onset Parkinson's disease. Neurology 1993 ; 43 : 1150-8.
96. Semchuk KM, Love EJ, Lee RG. Parkinson's disease and exposure to agricultural work and pesticide chemicals. Neurology 1992 ; 42 : 1328-35.
97. Semuck KM, Love EJ, Lee RG. Parkinson's disease : a test of the multifactorial etiologic hypothesis. Neurology 1993 ; 43 : 1173-80.
98. Fleming L, Mann JB, Bean J, Briggle T, Sanchez-Ramos JR. Parkinson's disease and brain levels of organochlorine pesticides. Ann Neurol 1994 ; 36 : 100-3.
99. Fiore MC, Anderson HA, Hong R et al. Chronic exposure to aldicarb-contaminated groundwater and human immune function. Envir Res 1986 ; 41 : 633-45.
100. Misra UK, Nag D, Misra NK, Mehra MK, Ray PK. Some observations on the macula of pesticide workers. Human Toxicol 1985 ; 4 : 135-5.
101. Carry VF, Kelly JT, Sprafka JM, Edwards S, Griffth J. Survey of health and use characterization of pesticide appliers in Minnesota. Arch Environ Health 1994 ; 49 : 337-43.
102. Lings S. Pesticide lung : a pilot investigation of fruit-growers and farmers during the spraying season. Br J Indus Med 1982 ; 39 : 370-6.
103. Lin JL, Liu L, Leu ML. Recovery of respiratory function in survivors with Paraquat intoxication. Arch Environ Health 1995 ; 50 : 432-9.
104. Senthilselvan A, McDuffie HH, Dosman JA. Association of asthma with use of pesticides. Am Rev Respir Dis 1992 ; 1466 : 884-7.
105. Zuskin E, Mustajbegovic J, Schachter N, Kern J, Pavicic D. Respiratory function in vineyard and orchard workers. Am J Indus Med 1997 ; 30 : 250-2.
106. Guo YL, Wang BJ, Wang JD. Prevalence of dermatoses and skin sensitisation associated with use of pesticides in fruit farmers of southern Taiwan. Occup Environ Med 1996 ; 53 : 427-31.