Selective delivery of 10B to soft tissue sarcoma using 10B-L-borophenylalanine for boron neutron capture therapy

British Journal of Radiology

Volumn 71, Issue MAR., 1998, Pages 320-323

  Pignol, J P ^a,e   Oudart, H ^b   Chauvel, P ^c   Sauerwein, W ^d   Gabel, D ^b   Prevot, G ^a  

^a Hopital du Hasenrain CH de Mulhouse   (France)

^b INSTITUT DE RECHERCHES SUBATOMIQUES   (France)

^c CENTRE ANTOINE LACASSAGNE   (France)

^d UNIVERSITY OF DUISBURG ESSEN   (Germany)

^e UNIVERSITY OF BREMEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BORON DERIVATIVE;

ANIMAL; ARTICLE; CANCER TRANSPLANTATION; METABOLISM; NEUTRON CAPTURE THERAPY; RAT; WISTAR RAT; YOSHIDA SARCOMA;

ANIMALS; BORON COMPOUNDS; BORON NEUTRON CAPTURE THERAPY; NEOPLASM TRANSPLANTATION; RATS; RATS, WISTAR; SARCOMA, YOSHIDA;

EID: 0032015831     PISSN: 00071285     EISSN: None     Source Type: Journal    
DOI: 10.1259/bjr.71.843.9616243     Document Type: Article

References (10)

1. Barth RF, Soloway AH, Fairchild RG, Brugger RM. Boron neutron capture therapy for cancer: realities and prospects. Cancer 1992;7:2995-3007.
2. Gabel D, Fairchild RG, Larsson, B, Borner HG. The relative biological effectiveness in V79 Chinese hamster cells of the neutron capture reactions in boron and nitrogen. Radiât Res 1984;98:307-16.
3. Fairchild RG, Bond VP. Current status of 10Bneutron capture therapy: enhancement of tumour dose via beam filtration and dose rate, and the effects of these parameters on minimum boron content: a theoretical evaluation. Int J Radiât Oncol BiolPhys 1985;! 1:831-40.
4. Gaynor JJ, Tan CC, Casper ES, Collin CF, Friedrich C, Shiu M, et al. Refinement of clinicopathologic staging for localized soft tissue sarcoma of the extremities: A study of 423 adults. J Clin Oncol 1992;10:1317-29.
5. Ravaud A, Bui NB, Coindre JM, Lagarde P, Tramond P, Bonichon F, et al. Prognostic variables for the selection of patients with operable soft tissue sarcomas to be considered in adjuvant chemotherapy trials. Br J Cancer 1992;66:961-9.
6. Bell RS, O'Sullivan B, Davis A, Langer F, Cummings B, Fornasier VL. Functional outcome in patients treated with surgery and irradiation for soft tissue tumours. J Surg Oncol 1991;48:224-31.
7. Coderre JA, Glass JD, Fairchild RG, Roy U, Cohen S, Fand I. Selective targeting of boronophenylalanine to melanoma in BALB/c mice for neturon capture therapy. Cancer Res 1987;47:6377-83.
8. Pignol JP, Abbe JC, Thellier M, Stampfler A. Neutron capture radiography applied to the investigation of boron-10 biodistribution in animals: improvements in techniques of imaging and quantitative analysis. Nucl Instr Meth Phys Res B 1994;94:516-22.
9. Gabel D, Holstein H, Larsson B, Gille L, Ericson G, Sacker D, et al. Quantitative neutron capture radiography for studying the biodistribution of tumour-seeking boron-containing compounds. Cancer Res 1987;47:5451-4.
10. Belkhou R, Abbe JC, Pham P, Jasner N, Masserelli R. Uptake and metabolism of boronophenylalanine in human uveal melanoma cells in culture. Relevance to boron neutron capture therapy of cancer cells. Amino Acids 1995;8:217-29.