Shorth communication: Expression of two different FMOs in sheep liver

Drug Metabolism and Disposition

Volumn 26, Issue 3, 1998, Pages 284-287

  Longin Sauvageon, C ^a   Lattard, V ^b   Lilaz Michel, C ^b   Buronfosse, T ^b   Benoit, E ^b  

^a VETAGRO SUP   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALBENDAZOLE; ANTISERUM; CYTOCHROME P450; MICROSOME ENZYME; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; THIAMAZOLE; TRIMETHYLAMINE; DIMETHYLANILINE MONOOXYGENASE; DIMETHYLANILINE MONOOXYGENASE (N-OXIDE FORMING); DRUG DERIVATIVE; IMIPRAMINE; METHIONINE; METHIONINE SULFOXIDE; METHYLAMINE; OXYGENASE;

ANIMAL TISSUE; ARTICLE; CATALYSIS; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME PURIFICATION; LIVER METABOLISM; LIVER MICROSOME; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SHEEP; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; BIOSYNTHESIS; CHEMISTRY; ENZYMOLOGY; FEMALE; GENE EXPRESSION; GENETICS; KINETICS; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; FEMALE; GENE EXPRESSION; IMIPRAMINE; KINETICS; METHIMAZOLE; METHIONINE; METHYLAMINES; MICROSOMES, LIVER; MOLECULAR SEQUENCE DATA; OXYGENASES; SHEEP;

EID: 0032015189     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Ziegler DM (1980) Microsomal flavin-containing monooxygenase; oxygenation of nuleophilic nitrogen and sulfur compound. In Enzymatic basis of detoxification (Jakoby WB ed) Pp. 201-227, Academic Press, New York.
2. Waiz MA, Ayezh R, Mitchell SC, Idle JR and Smith RL (1987) Trimethylaminuria (fish-odour-syndrome); an inborn error of oxidative metabolism. Lancet 1:634-635.
3. Duescher RJ, Lawton MP, Philpot RM and Elfarra AA (1994) Flavin-containing monooxygenase (FMO)-dependent metabolism of methionine and evidence for FMO3 being the major FMO involved in methionine sulfoxidation in rabbit liver and kidney microsomes. J Biol Chem 269:17525-17530.
4. Krause RJ, Ripp SL, Sausen PJ, Overby LH, Philpot RM and Elfarra AA (1996) Characterization of the methionine S-oxidaze activity of rat liver and kidney for FMO3 being the major catalyst. Arch Biochem Biophys 333:109-116.
5. Lawton MP, Cashman JR, Cresteil T, Elfarra AA, Hines RN, Hodgson E, Kimura T, Ozols J, Phillips IR, Philpot RM, Poulsen LL, Rettie AE, Sheppard EA, Williams DE and Ziegler DM (1994) A nomenclature for the mammalia flavin-containing monooxygenase gene family based on amino acid sequence identities. Arch Biochem Biophys 308:254-257.
6. Hines RN, Cashman JR, Philpot RM, Williams DE and Ziegler DM (1993) The mammalian flavin-containing monooxygenases: molecular characterization and regulation of expression. Tox Appl Pharm 125:1-6.
7. Ziegler DM and Mitchell SC (1972) Microsomal oxydase IV: properties of a mixed-function amine oxidase isolated from pig liver microsomes. Arch Biophys Biochem 150:116-125.
8. 2 terminal segments homologous to the flavin containing NADPH monooxygenase of Pseudomonas fluorescence. Biochem Biophys Res Commun 163:49-55.
9. Ozols J (1994) Isolation and structure of a third form of liver microsomal flavin monooxygenase. Biochemistry 33:3751-3757.
10. Cashman JR (1995) Structural and catalytic properties of the mammalian flavin-containing monooxygenase. Chem Res Toxicol 8:165-181.
11. Lomri N, Gu Q and Cashman JR (1992) Molecular cloning of the flavin-containing monooxygenase (form II) cDNA from adult human liver. Proc Natl Acad Sci USA 89:1685-1689.
12. Moroni P, Longin-Sauvageon C and Benoit E (1995a) The flavin-containing monooxygenases in rat liver: evidence for the expression of a second form different from FMO1. Biochem Biophys Res Commun 212:820-826.
13. Galtier P, Alvinerie M and Delatour P (1986) In vitro sulfoxidation of albendazole by ovine liver microsomes: assay and frequency of various xenobiotics. Am J Vet Res 47:447-452.
14. Moroni P, Buronfosse T, Longin-Sauvageon C, Delatour P and Benoit E (1995b) Chiral sulfoxidation of albendazole by the flavin adenine dinucleotide-containing and cytochrome P450-dependent monooxygenases from rat liver microsomes. Drug Metab Dispos 23:160-165.
15. Williams DE, Meyers HH and Dutchuck MS (1989) Distinct pulmonary and hepatic forms of flavin-containing in sheep. Comp Biochem Physiol 938:465-470.
16. Dixit A and Roche TE (1984) Spectrophotometric assay of the flavin-containing monooxygenase and changes in its activity in female mouse liver with nutritional and diurnal conditions. Arch Biochem Biophys 223:50-63.
17. Bôhlen P, Stein S, Dairman W and Underfriend S (1973) Fluorometric assay of proteins in the nanogram range. Arch Biochem Biophys 155:50-63.
18. Bradford MA (1976) A rapid sensitive method for the quantitation of microgram quantities of protein utilizing the principal of protein-dye binding. Anal Biochem 72:248-254.
19. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
20. Towbin H, Stahelin T and Gordon J (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 89:4350-4354.
21. Gill PE and Murray W (1978) Algorithms for the solution of the nonlinear least-squares problems.nal. SIAM J Numer Anal 15:977-992.
22. Bard Y (1974) Nonlinear parameter estimation2E Academic Press.
23. Lemoine A, Johan M and Cresteil T ( 1990) Evidence for the presence of distinct favin-containing monooxygenases in human tissues. Arch Biochem Biophys 276:336-342.