Equine ulcerative keratomycosis: Visual outcome and ocular survival in 39 cases (1987-1996)

Equine Veterinary Journal

Volumn 30, Issue 2, 1998, Pages 109-116

  Andrew, S E ^a   Brooks, D E ^a   Smith, P J ^a   Gelatt, K N ^a   Chmielewski, N T ^a   Whittaker, C J G ^a  

^a University of Florida College of Veterinary Medicine   (United States)

Author keywords

Cornea; Fungal; Horse; Keratitis; Keratomycosis; Visual outcome

Indexed keywords

ASPERGILLUS; BACTERIA (MICROORGANISMS); EQUIDAE; EQUUS CABALLUS; FUNGI; FUSARIUM;

ANTIFUNGAL AGENT; MICONAZOLE; POVIDONE IODINE; SULFADIAZINE SILVER; TOPICAL ANTIINFECTIVE AGENT;

ANIMAL; ANIMAL DISEASE; ARTICLE; ASPERGILLUS; CORNEA STROMA; CORNEA ULCER; CYTOCHEMISTRY; CYTOLOGY; FEMALE; FUNGAL EYE INFECTION; FUSARIUM; HORSE; HORSE DISEASE; ISOLATION AND PURIFICATION; MALE; MICROBIOLOGY; PHYSIOLOGY; RETROSPECTIVE STUDY; TREATMENT OUTCOME; VISION;

ANIMALS; ANTI-INFECTIVE AGENTS, LOCAL; ANTIFUNGAL AGENTS; ASPERGILLUS; CORNEAL STROMA; CORNEAL ULCER; EYE INFECTIONS, FUNGAL; FEMALE; FUSARIUM; HISTOCYTOCHEMISTRY; HORSE DISEASES; HORSES; MALE; MICONAZOLE; POVIDONE-IODINE; RETROSPECTIVE STUDIES; SILVER SULFADIAZINE; TREATMENT OUTCOME; VISION;

EID: 0032014893     PISSN: 04251644     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-3306.1998.tb04469.x     Document Type: Article

References (27)

1. Alexopoulos, C.J , Mims, C.W. and Blackwell, M (1996) Introductory Mycology. 4th edn. John Wiley and Sons Inc., New York, pp 26-60.
2. Barton, M.H (1992) Equine keratomycosis. Comp cont. Educ pract. Vet 14, 936-944.
3. Bates, E E. and McCartney, D.L (1996) A study of the potential effect of povidoneiodine solution in treating ocular fungal pathogens. Invest. Ophthalmol. vis. Sci. 37, S872
4. Beech, J. and Sweeney, C.R. (1983) Keratomycosis in 11 horses. Equine vet. J., Suppl. 2, 39-44.
5. Bistner, S.I. and Riis, R.C. (1979) Clinical aspects of mycotic keratitis in the horse. Cornell Vet. 69, 364-372
6. Chmielewski, N.T., Brooks, D E., Smith, P.J., Hendrix, D.V.H., Whittaker, C. and Gelatt, K.N. (1997) Visual outcome and ocular survival following iris prolapse in the horse: A review of 32 cases. Equine vet J. 29, 31-39.
7. Coad, C.T., Robinson, N.M. and Wilhelmus, K.R. (1985) Antifungal sensitivity testing for equine keratomycosis. Am. J. vet. Res. 46, 676-678.
8. Collins, M.B., Ethell, M T. and Hodgson, D.R. (1994) Management of mycotic keratitis in a horse using a conjunctival pedicle graft Aust. ver. J. 71, 298-299.
9. Debono, M. and Gordee, R.S. (1994) Antibiotics that inhibit fungal cell wall development. Ann. Rev. Microbiol 48, 471-497.
10. Foster, C.S. and Stefanyszyn, M (1979) Intraocular penetration of miconazole in rabbits. Arch. Ophthalmol. 97, 1703-1706.
11. Foster, C S., Lass, J.H., Moran-Wallace, K. and Giovanoni, R. (1981) Ocular toxicity of topical antifungal agents. Arch. Ophthalmol 99, 1081-1084.
12. Friedman, D.S , Schoster, J.V., Pickett, J.P , Dubielzig, R.R., Czuprynski, C., Knoll, J.S and Wolfgram, L.J (1989) Pseudallescheria boydii keratomycosis in a horse. J. Am. vet. med. Ass. 195, 616-618.
13. Grahn, B., Wolfer, J., Keller, C. and Wilcock, B (1993) Equine keratomycosis: Clinical and laboratory findings in 23 cases Prog. vet. comp. Ophthalmol. 3, 2-7.
14. Hale, L.M. (1969) The treatment of corneal ulcer with povidone-iodine (Betadine). N. C. Med. J. 30, 54-56.
15. Hendrix, D.V.H., Brooks, D.E., Smith, P J., Miller, T.R., Whittaker, C., Gelatt, K.N. and Pellicane, C. (1995) Corneal stromal abscesses in the horse: a review of 24 cases. Equine vet. J 27, 440-447.
16. Johns, K J. and O'Day, D.M. (1988) Pharmacologic management of keratomycoses. Surv. Ophthalmol 33, 178-188.
17. Kern, T.J., Brooks, D.E. and White, M.M. (1983) Equine keratomycosis: Current concepts of diagnosis and therapy. Equine. vet. J., Suppl 2, 33-38.
18. Lamps, C.A., Oeltmann, T.N., Collins, M.J., Robinson, R.D., Logan, R.A., Head, W.S. and O'Day, D.M. (1995) Development of a chitin assay for the quantification of fungus. Curr. Eye Res 14, 637-641.
19. Moore, C.P., Fales, W.H., Whittington, P. and Bauer, L. (1983) Bacterial and fungal isolates from Equidae with ulcerative keratitis. J. Am vet. med. Ass. 182, 600-603.
20. Moore, C.P., Collins, B.K. and Fales, W.H. (1995) Antibacterial susceptibility patterns for microbial isolates associated with infectious keratitis in horses: 63 cases (1986-1994). J Am. vet. med. Ass. 207, 928-933.
21. Moore, C.P., Heller, N , Majors, L J , Whitley, R.D., Burgess, E.C. and Weber, J. (1988) Prevalence of ocular microorganisms in hospitalized and stabled horses. Am. J. vet Res 49, 773-777.
22. O'Day, D M., Ray, W.A., Robinson, R. and Head, W.S. (1984) Efficacy of antifungal agents in the cornea. II. Influence of corticosteriods. Invest. Ophthalmol. vis. Sci. 25, 331-335
23. O'Day, D.M, Ray, W., Head, S., Robinson, R.D. and Williams, T.E. (1991) Influence of corticosteroid on experimentally induced keratomycosis. Arch. Ophthalmol. 109, 1601-1604.
24. Samuelson, D.A., Andresen, T.L. and Gwin, R M. (1984) Conjunctival fungal flora in horses, cattle, dogs, and cats. J. Am. vet. med. Ass. 184, 1240-1242.
25. Whitley, R D , Burgess, E.C. and Moore, C.P (1983) Microbial isolates of the normal equine eye. Equine vet. J., Suppl. 2, 138-140.
26. Wilcock, B.P. (1996) Pathology of the cornea, sclera and conjunctiva. In: The Histologic Basis of Ocular Disease. ACVO Basic Sciences Course, University of Florida, Gainesville, Florida.
27. Wlodkowski, T J. and Rosenkranz, H.S (1973) Antifungal activity of silver sulphadiazine. Lancet ii, 739-740