Pharmacokinetics of ceftriaxone in neonatal foals

Equine Veterinary Journal

Volumn 30, Issue 2, 1998, Pages 163-165

  Ringger, N C ^a   Brown, M P ^a   Kohlepp, S J ^b   Gronwall, R R ^a   Merritt, K ^a  

^a University of Florida College of Veterinary Medicine   (United States)

^b PROVIDENCE PORTLAND MEDICAL CENTER   (United States)

Author keywords

Ceftriaxone; Foal; Horse; Meningitis; Pharmacokinetics; Sepsis

Indexed keywords

EQUUS CABALLUS;

CEFTRIAXONE; CEPHALOSPORIN DERIVATIVE;

ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORSE; INTRAVENOUS DRUG ADMINISTRATION; METABOLISM; NEWBORN;

ANIMALS; ANIMALS, NEWBORN; CEFTRIAXONE; CEPHALOSPORINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HORSES; INJECTIONS, INTRAVENOUS;

EID: 0032014745     PISSN: 04251644     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-3306.1998.tb04477.x     Document Type: Article

References (23)

1. Baggot, J.D. and Short, C.R. (1984) Drug disposition in the neonatal animal with particular reference to the foal. Equine vet. J 16, 354-367.
2. Brewer, B. (1990) Neonatal infections. In. Equine Clinical Neonatology. Eds: A.M. Koterba, W H. Drummond and PC Kosch. Lea and Febiger, Philadelphia, pp 295-316.
3. Brogden, R.N. and Ward, A (1988) Ceftriaxone a reappraisal of its antibacterial activity and pharmacokinetic properties, and an update on its therapeutic use with particular reference to once daily administration Drugs. 35, 604-645.
4. Bryan, J.P., Rocha, H., da Silva, H.R., Taveres, A., Sande, M.A. and Scheld, WM (1985) Comparison of ceftriaxone and ampicillin plus chloramphenical for the therapy of acute bacterial meningitis Antimicrob Agents Chemother. 28, 361-368.
5. Congeni, B.L. (1984) Comparison of ceftriaxone and traditional therapy of bacterial meningitis Antimicrob Agents Chemother. 25, 40-44
6. Gardner, S.Y. and Aucoin, D.P. (1994) Pharmacokinetics of ceftriaxone in mares. J. Vet. Pharmacol. Ther. 17, 155-156.
7. Gibaldi, M. and Perrier, D (1982) Noncompartmental analysis based on statistical moment theory. In: Pharmacokinetics, 2nd edn Marcel Dekker, Inc New York. pp 409-417.
8. Granich, G.G. and Krogstad, D.J. (1987) Ion pair high-performance liquid Chromatographic assay for ceftriaxone. Antimicrob Agents Chemother 31, 385-388.
9. Green, S.L. and Mayhew, I.G. (1990) Neurologic disorders. In: Equine Clinical Neonatology. Eds: A.M Koterba, W.H. Drummond and P.C. Kosch. Lea and Febiger, Philedelphia, pp 513-520.
10. Hanberger, H. (1992) Pharmacodynamic effects of antibiotic studies on bacterial morphology, initial killing, postantibiotic effect and effective regrowth time. Scand. J. infect. Dis. 81, 1-52.
11. Heim-Duthoy, K.L., Caperton, E.M., Pollock, R., Matzke, G.R., Enthoven, D. and Peterson, P.K (1990) Apparent biliary pseudolithiasis during ceftriaxone therapy Antimicrob. Agents Chemother. 34, 1146-1149.
12. Isaksson, B , Hanberger, H , Maller, R., Nilsson, L E. and Nilsson, M (1991) Synergistic PAE of amikacin in combination with beta-lactam antibiotics on gram-negative antibiotics J. Antimicrob. Chemother. 28, 25-34
13. Koterba, A.M and House, J K (1996) Neonatal Infection. In: Large Animal Internal Medicine, 2nd edn. Mosby, Philadelphia, pp 344-353.
14. Marchou, B., Tho, T.V. and Armengaud, M. (1981) Diffusion of ceftriaxone (RO13™9904/001) in the cerebral spinal fluid: comparison with other beta-lactam antibiotics in dogs with healthy meninges and in dogs with experimental meningitis. Chemother. 27, 37-41.
15. Raisis, A.L , Hodgson, J.L. and Hodgson, D.R. (1996) Equine neonatal septicaemia: 24 cases. Aust. vet. J. 73, 137-140.
16. Richards, D.M., Heel, R C , Brogden, R.N., Speight, T.M and Avery, G.S (1984) Ceftriaxone: a review of its antibacterial activity, pharmacological properties, and therapeutic use. Drugs 2, 469-527.
17. Ringger, N C., Pearson, E.G., Gronwall, R. and Kohlepp, S.J (1996) Pharmacokinetics of ceftriaxone in healthy horses. Equine vet. J. 28, 476-479.
18. Schaad, U.B., McCracken, G.H. and Thomas, M.L. (1981) Pharmacokinetics and bacteriological efficacy of moxalactam, cefotaxime, cefoperazone and rocephin in experimental bacterial meningitis. J. infect Dis. 143, 156-163.
19. Schaad, U.B., Suter, S., Gianella-Borradori, A., Pfenninger, J., Auckenthaler, R., Bernath, O , Cheseaux, J.J. and Wedgwood, J (1990) A comparison of ceftriaxone and cefuroxime for the treatment of bacterial meningitis in children N. Engl J. Med. 322, 141-147
20. Scheld, W.M., Rocha, H., Sande, M.A. and Bryan, J.P (1984) Rationale for clinical trials evaluating ceftriaxone in the therapy of bacterial meningitis Am. J. Med 77, 42-49.
21. Seddon, M , Wise, R., Gillette, A.P. and Livingston, R. (1980) Pharmacokinetics of R013-9904, a broad spectrum cephalosporin. Antimicrob. Agents Chemother. 18, 240-242
22. Soback, S and Ziv, G. (1988) Pharmacokinetics and bioavailability of ceftriaxone administered intravenously and intramuscularly to calves Am. J vet. Res 49, 535-538.
23. Van Reempts, P J., Van Overmeire, B., Mahieu, L M and Vanacker, K J (1995) Clinical experience with ceftriaxone treatment in the neonate. Chemother. 41, 316-322