Inhibition of nitric oxide synthesis aggravates myocardial ischemia in hemorrhagic shock in constant pressure model

Shock

Volumn 9, Issue 3, 1998, Pages 204-209

  Adachi, Takeshi ^a   Hori, Shingo ^a,c   Miyazaki, Koji ^a   Nakagawa, Masahiro ^a   Inoue, Soshin ^a   Ohnishi, Yozo ^a   Nakazawa, Hiroe ^b   Aikawa, Naoki ^a   Ogawa, Satoshi ^a  

^a KEIO UNIVERSITY   (Japan)

^b TOKAI UNIVERSITY   (Japan)

^c KEIO UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CATECHOLAMINE; ENZYME INHIBITOR; LACTIC ACID; N(G) NITROARGININE METHYL ESTER; NICOTINAMIDE ADENINE DINUCLEOTIDE; NITRIC OXIDE; OXYGEN;

ANIMAL; AORTA; ARTICLE; BLOOD; DISEASE MODEL; DOG; FLUORESCENCE; FREEZING; HEART MUSCLE ISCHEMIA; HEMODYNAMICS; HEMORRHAGIC SHOCK; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ADENOSINE TRIPHOSPHATE; ANIMALS; AORTA; CATECHOLAMINES; DISEASE MODELS, ANIMAL; DOGS; ENZYME INHIBITORS; FLUORESCENCE; FREEZING; HEMODYNAMIC PROCESSES; LACTIC ACID; MYOCARDIAL ISCHEMIA; NAD; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; OXYGEN; SHOCK, HEMORRHAGIC;

EID: 0032014651     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-199803000-00008     Document Type: Article

References (37)

1. Moncada S, Radomski MW, Palmer RMJ: Endothelium-derived relaxing factor: Identification as nitric oxide and role in the control of vascular tonus and platelet function. Biochem Pharmacol 37:2495-2501, 1988.
2. Rees DD, Palmer RMJ, Moncada S: Role of endothelium-derived nitric oxide in the regulation of blood pressure. Proc Natl Acad Sci USA 86:3375-3378, 1989.
3. Petros A, Bennet D, Vallance P: Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock. Lancet 338:1557-1558, 1991.
4. Thiemermann C: The role of the L-arginine:nitric oxide pathway in circulatory shock. Adv Pharmacol 28:45-79, 1994.
5. Szabo C: Alternation in nitric oxide production in various forms of circulatory shock. New Horiz 3:2-33, 1995.
6. G-monomethyl-L-arginine. J Cardiovasc Pharmacol 20(Suppl 12):S132-S134, 1992.
7. G-methyl-L-arginine, an inhibitor of nitric oxide synthesis. Biochem Biophys Res Commun 172:1132-1138, 1990.
8. Szabo C, Mitchell JA, Thiemermann C: Nitric oxide mediated hyporeactivity to norepinephrine precedes nitric oxide synthase induction in endotoxin shock. Br J Pharmacol 108:786-792, 1993.
9. Lieberthal W, McGarry AE, Sheils J, Valeri CR: Nitric oxide inhibition in rats improves blood pressure and renal function during hypovolemic shock. Am J Physiol 261:F868-F872, 1991.
10. Zingarelli B, Squadrito F, Altavilla D, et al: Evidence for a role of nitric oxide in hypovolemic hemorrhagic shock. J Cardiovasc Pharmacol 19: 982-986, 1992.
11. G-methyl-L-arginine restores arterial pressure in hemorrhaged rats. Circ Shock 40:47-52, 1993.
12. Thiemermann C, Szabo C, Mitchell JA, Vane JR: Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide. Proc Natl Acad Sci USA 490: 267-271, 1993.
13. Balligand JL, Kelly RA, Marsden PA, Smith TW, Michel T: Control of cardiac muscle cell function by an endogenous nitric oxide signaling system. Proc Natl Acad Sci USA 90:347-351, 1993.
14. Balligand JL, Ungureanu D, Kelly RA, et al: Kobzik L, Pimental D, Michel T, Smith TW: Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium. J Clin Invest 91:2314-2319, 1993.
15. Finkel MS, Oddis CV, Jacob TD, Watkins SC, Hattler BG, Simmons RL: Negative inotropic effects of cytokine on the heart mediated by nitric oxide. Science 257:387-389, 1992.
16. Smith TJ, Canty JJ: Modulation of coronary autoregulatory responses by nitric oxide. Evidence for flow-dependent resistance adjustments in conscious dogs. Circ Res 73:232-240, 1993.
17. Kostic M, Schrader J: Role of nitric oxide in reactive hyperemia of the guinea pig heart. Circ Res 70:208-212, 1992.
18. Downey JM, Kirk ES, Cowan DF, Sonnenblick EH, Urschel CW: The adequacy of coronary blood flow during acute hypotension. Circ Shock 3:83-91, 1976.
19. Miyazaki K, Hori S, Inoue S, et al: Characterization of energy metabolism and blood flow distribution in myocardial ischemia in hemorrhagic shock. Am J Physiol 1997. In press.
20. Hori S, Nakazawa H, Ohnishi Y, et al: A rapid cross-sectioning and freeze-clamping device for the beating canine heart. J Mol Cell Cardiol 21:203-210, 1989.
21. Bessho M, Tajima T, Hori S, et al: NAD and NADH values in rapidly sampled dog heart tissue by two different extraction methods. Anal Biochem 182:304-308, 1989.
22. Shimojo N, Naka K, Nakajima C, Yoshikawa C, Okuda K, Okada K: Test-strip method for measuring lactate in whole blood. Clin Chem 35: 1992-1994, 1989.
23. Spielmann H, Jacob-Muller U, Shultz P: Simple assay of 0.1-1.0 pmol of ATP, ADP and AMP in single somatic cell using purified luciferin luciferase. Anal Biochem 113:172-178, 1981.
24. Lust WD, Barbehenn GK, Passonneau JV: The enzymatic measurement of adenosine nucleotides and p-creatine in picomole amounts. Anal Biochem 110:258-266, 1981.
25. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ: Protein measurement with the folin phenol reagent. J Biol Chem 193:265-275, 1951.
26. Westenberger U, Thanner S, Ruff HH, Gersonde K, Sutter G, Trentz O: Formation of free radicals and nitric oxide derivative of hemoglobin in rats during shock syndrome. Free Radic Res Commun 11:167-178, 1990.
27. Koyama S, Sawano F, Matsuda Y, et al: Spatial and temporal differing control of sympathetic activation during hemorrhage. Am J Physiol 262: R579-R585, 1992.
28. Bond RF, Johnson G: Vascular adrenergic interaction during hemorrhagic shock. Fed Proc 44:281-289, 1985.
29. Suga H, Hisano R, Goto Y, Yamada O, Igarashi Y: Effect of positive inotropic agents on the relation between oxygen consumption and systolic pressure volume area in canine left ventricle. Circ Res 53:306-318, 1983.
30. Ando H, Nakano E, Ueno Y, Tokunaga K: New technique for analysis of cardiac energetic using a modified Fenn equation. J Thorac Cardiovasc Surg 97:565-574, 1989.
31. Shen W, Xu X, Ochoa M, Zhao G, Wolin MS, Hintze TH: Role of nitric oxide in the regulation of oxygen consumption in conscious dogs. Circ Res 75:1086-1095, 1994.
32. Xie YW, Shen W, Zhao G, et al: Role of endothelium-derived nitric oxide in the modulation of canine myocardial mitochondrial respiration in vivo: Implication for the development of heart failure. Circ Res 79:381-387, 1996.
33. Cohen RA, Weisbrod RM: Endothelium inhibits norepinephrine release from adrenergic nerves of rabbit carotid artery. Am J Physiol 254:H871-H878, 1988.
34. Schwarz P, Diem R, Dun NJ, Forstermann U: Endogenous and exogenous nitric oxide inhibits norepinephrine release from rat heart sympathetic nerves. Circ Res 77:841-848, 1991.
35. G-methyl-L-arginine, an inhibitor of L-arginine-derived nitric oxide synthesis, stimulates renal sympathetic nerve activity in vivo: A role for nitric oxide in the central regulation of sympathetic tone? Circ Res 70:607-611, 1992.
36. Nayler WG, Panagiotopoulos S, Elz JS, Sturrock WJ: Fundamental mechanism of action of calcium antagonists in myocardial ischemia. Am J Cardiol 59:75B-83B, 1987.
37. Avontuur JAM, Bruining HA, Ince C: Inhibition of nitric oxide synthesis causes myocardial ischemia in endotoxemic rats. Circ Res 76:418-425, 1995.