Mucin biosynthesis: Molecular cloning and expression of bovine lung mucin core 2 N-acetylglucosaminyltransferase cDNA

American Journal of Respiratory Cell and Molecular Biology

Volumn 18, Issue 3, 1998, Pages 343-352

  Li, Cheng Ming ^b   Adler, Kenneth B ^b   Cheng, Pi Wan ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BOVINAE; INSECTA; UNIDENTIFIED BACULOVIRUS;

BETA 1,3 GALACTOSYL O GLYCOSYL GLYCOPROTEIN BETA 1,6 ACETYLGLUCOSAMINYL TRANSFERASE; BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-ACETYLGLUCOSAMINYL TRANSFERASE; COMPLEMENTARY DNA; MUCIN; N ACETYLGLUCOSAMINYLTRANSFERASE; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BIOSYNTHESIS; CARBOHYDRATE ANALYSIS; CATTLE; COMPARATIVE STUDY; DNA SEQUENCE; ENZYMOLOGY; GENE LIBRARY; GENETICS; IMMUNOHISTOCHEMISTRY; LUNG; METHODOLOGY; MOLECULAR CLONING; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CARBOHYDRATE SEQUENCE; CATTLE; CLONING, MOLECULAR; DNA, COMPLEMENTARY; GENOMIC LIBRARY; IMMUNOHISTOCHEMISTRY; LUNG; MOLECULAR SEQUENCE DATA; MUCINS; N-ACETYLGLUCOSAMINYLTRANSFERASES; RECOMBINANT PROTEINS; RESEARCH DESIGN; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0032012973     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.18.3.2593     Document Type: Article

References (35)

1. Boat, T. F., P.-W. Cheng, and M. Leigh. 1993. In Biochemistry of Mucus in Airway Secretions. T. Takashima and S. Shimura, editors. Marcel Dekker, New York. 217-282.
2. Rademacher, T. W., R. B. Parekh, and R. A. Dwek. 1988. Glycobiology. Annu. Rev. Biochem. 57:785-838.
3. Olden, K., B. A. Bernard, M. J. Humphries, T. K. Yeo, F. T. Yeo, S. L. White, and J. B. Parent. 1985. Function of glycoprotein glycans. Trends Biochem. Sci. 10:78-82.
4. Strous, G. J., and J. Dekker. 1992. Mucin-type glycoprotein. Crit. Rev. Biochem. Mol. Biol. 27:57-59.
5. Wingert, W., and P.-W. Cheng. 1984. Mucin biosynthesis: characterization of rabbit small intestinal UDP-GlcNAc: galactoseβ3N-acetylgalactosamine (GlcNAc-GalNAc) β6 N-acetylglucosaminyltransferase. Biochemistry 23:690-697.
6. Piller, F., V. Piller, R. I. Fox, and M. Fukuda. 1988. T lymphocytic leukemia expresses complex, branched O-linked oligosaccharides on a major sialoglycoprotein leukosialin. J. Biol. Chem. 263:15146-15150.
7. Carlson, D. M. 1968. Structures and immunochemical properties of oligosacchandes isolated from pig submaxillary mucins. J. Biol. Chem. 243: 616-626.
8. Fukuda, M., S. R. Carlson, J. C. Klock, and A. Dell. 1989. Structure of O-linked oligosaccharides isolated from normal granulocytes, chronic myelogenous leukemia cells and acute myelogenous leukemia cells. J. Biol. Chem. 261:12796-12806.
9. Piller, F., F. Le Deist, K. I. Weinberg, R. Parkman, and M. Fukuda. 1991. Altered O-glycan synthesis in lymphocytes from patient with Wiskott-Aldrich syndrome. J. Exp. Med. 173:1501-1510.
10. Yousefi, S., E. Higgins, Z. Daoling, A. Pollex-Kruger, O. Hindsgaul, and J. W. Dennis. 1991. Increased UDP-GlcNAc:Galβ1-3GalNAc-R (GlcNAc to GalNAc)β1-6-N-acetylglucosaminyltransterase activity in metastatic murine tumor cell lines. J. Biol. Chem. 266:1772-1782.
11. Bierhuizen, M. F. A., and M. Fukuda. 1992. Expression cloning of a cDNA, encoding UDP-GlcNAc:Galβ1-3-GalNAc-R (GlcNAc to GalNAc) β1-6GlcNAc transferase by gene transfer into CHO cells expressing polyoma large tumor antigen. Proc. Natl. Acad. Sci. USA 89:9326-9330.
12. Warren, C. E., D. S. Smookler, and J. W. Dennis. 1995. UDP-GlcNAc:Galβ1-3GalNAc-R (GlcNAc to GaINAc) β1-6GlcNAc transferase (core 2-GnT) mouse cDNA sequence. GenBank Accession No. U19265.
13. Biurhuizen, M. F. A., M. G. Mattei, and M. Fukuda. 1993. Expression of the developmental I antigen by a cloned human cDNA encoding a member of a β-1.6-N-acetylglucosaminyltransferase gene family. Genes Dev. 7:468-174.
14. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press. Cold Spring Harbor, NY.
15. Sanger, F., S. Nockln, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463-5467.
16. Ropp, P. A., M. R. Little, and P.-W. Cheng. 1991. Mucin biosynthesis: purification and characterization of a mucin β6 N-acetylglucosaminyltransferase. J. Biol. Chem. 266:23863-23871.
17. Brockhausen, I., K. L. Matta, J. Orr. H. Schachter, A. Koenderman, and D. Van Den Eijden. 1986. Mucin synthesis: conversion of R1-β1-3Gal-R2 to β1-3(GlcNAcβ1-6)Gal-R2 and of R1β1-3GalNAc-R2 to R1β1-3 (GlcNAc β1-6) GalNAc-R2 by a β6-N-acetylglucosaminyltransferase in pig gastric mucosa. Eur. J. Biochem. 157:463-171.
18. Li, C. M., P.-W. Cheng, and K. B. Adler. 1993. Production and characterization of monoclonal antibodies against guinea pin tracheal mucins. Hybridoma 13:281-287.
19. Bierhuizen, M. F. A., K. Maemura, S. Kudo, and M. Fukuda. 1995. Genomic organization of core 2 and I branching β-1,6-N-acetylglucosaminyl-transferases: implication for evolution of the β-1,6-N-acetylglucosaminyl-transferase gene family. Glyacoiology 5:417-425.
20. Voet, D., and J. G. Voet. 1990. Biochemistry. John Wiley & Sons. New York. 264.
21. Cheng, P.-W., W. Wingert, M. Little, and R. Wei. 1985. Mucin biosynthesis: properties of a bovine tracheal mucin β6-GlcNAc transferase. Biochem. J. 227:405-412.
22. Kleene, R., and F. G. Berger. 1993. The molecular and cell biology of glycosyltransferases. Biochem. Biophys. Acta 1154:283-325.
23. Paulson, J. C., and K. J. Colley. 1989. Glycosyltransferases: structure, localizalion, and control of cell type-specific glycosylation. J. Biol. Chem. 264: 17615-17618.
24. Bustos, M. M., V. A. Luckow, L. R. Griffing, M. D. Summers, and T. C. Hall. 1988. Expression, glycosylation, and secretion of phaseolin in a baculovirus system. Plant Mol. Biol. 10:475-488.
25. Lebacq, A. M., P. G. Kasprzyk, M. G. Raum, K. Van Wyke, J. A. Lebacq, and J. F. Baltey. 1988. Posttranslational processing of endogenous and baculovirus-expressed human gastric-releasing peptide precursor. Mol. Cell Biol. 8:3129-3135.
26. Kornfeld, R., and S. Kornfeld. 1985. Assembly of asparagine-linked oligosaccharides. Annu. Rev. Biochem. 54:631-664.
27. Thomsen, D. R., L. E. Post, and A. P. Elhammer. 1990. Structure of O-glycosidically linked oligosaccharides synthesized by insect cell line Sf 9. J. Cell. Biochem. 43:67-79.
28. O'Reilly, D. R., L. K. Miller, and V. A. Luckow. 1994. Baculovirus Expression Vectors - Laboratory Manual. Oxford University Press, New York. 295.
29. Joziasse, D. H., N. L. Shaper, L. S. Salyer, D. H. Van Den Eijnden, A. C. Van der Spoel, and J. H. Shaper. 1990. α1-3 Galactosyltransferase: the use of recombinant enzyme for synthesis of α-galactosylated glycoconjugates. Eur. J. Biochem. 191:75-83.
30. Sarkar, M., and H. Schachter. 1992. Impression of UDP-GlcNAcα3-D-mannoside β1,2 GlcNAc TF 1 in insect cells. Glycobiology 2:483-491.
31. Homa, F. L., T. Hollander, D. J. Lehman, D. R. Thomsen, and A. P. Elhammer. 1993. Isolation and expression of a cDNA clone encoding a bovine UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase. J. Biol. Chem. 268:12609-12616.
32. Potvin, B., R. Kumar, D. R. Howard, and P. Stanley. 1990. Transfection of a human α-(1,3) fucosyltransferase gene into chinese hamster ovary cells. J. Biol. Chem. 265:1615-1622.
33. Weston, B. W., R. P. Nair, R. D. Larsen, and J. B. Lowe. 1992. Isolation of a novel human α(1,3) fucosyltransferase gene and molecular comparison to the human Lewis blood group α(1.3/1.4) fucosyltransferase gene. J. Biol. Chem. 267:4152-1160.
34. Shaper, J. H., and N. L. Shaper. 1992. Enzymes associated with glycosylation. Curr. Opin. Struct. Biol. 2:701-709.
35. Shur, B. D. 1991. Cell surface α1,4 galactosyltransferase: twenty years later. Glycobiology 1:563-575.