Trp64Arg Mutation of β3-Adrenergic Receptor and Non-Insulin Dependent Diabetes Mellitus

Internal Medicine

Volumn 37, Issue 3, 1998, Pages 345-

  Sakane, Naoki ^a   Yoshida, Toshihide ^b   Yoshioka, Keiji ^b   Umekawa, Tunekazu ^b   Kogure, Akinori ^b   Kondo, Motoharu ^b  

^a Ayabe Municipal Hospital   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT; ARGININE; BETA 3 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; INSULIN; MESSENGER RNA; TRYPTOPHAN;

ADIPOSE TISSUE; ALLELE; ANIMAL; BODY MASS; GENE FREQUENCY; GENETICS; GENOTYPE; HUMAN; INSULIN RESISTANCE; METABOLISM; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; NOTE; POINT MUTATION; RAT;

ADIPOSE TISSUE; ALLELES; ANIMALS; ARGININE; BODY MASS INDEX; DIABETES MELLITUS, TYPE 2; GENE FREQUENCY; GENOTYPE; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; MIDDLE AGED; POINT MUTATION; RATS; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, ADRENERGIC, BETA-3; RNA, MESSENGER; TRYPTOPHAN;

EID: 0032012381     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.37.345     Document Type: Article

References (5)

1. Arii K, Suehiro T, Yamamoto M, et al. Trp64Arg mutation of p3-adrenergic receptor and insulin sensitivity in subjects with glucose intolerance. Intern Med 36: 603, 1997.
2. Yoshioka K, Yoshida T, Sakane N, et al. Association of Trp64Arg mutation of the (33-adrenergic receptor gene with NIDDM, current and maximal body mass index. Diabetologia 39: 1410, 1996 (letter, comment).
3. Abe H, Minokoshi Y, Shimazu T. Effect ofa (33-adrenergic agonist, BRL 35135A, on glucose uptake in rat skeletal muscle in vivo and vitro. J Endocrinol 139: 479, 1993.
4. Higashi K, Ishikawa T, Ito T, Yonemura A, Shige H, Nakamura H. Association of a genetic variation in the p3-adrenergic receptor gene with coronary heart disease among Japanese. Biochem Biophys Res Commun 232: 728, 1997.
5. Sakane N, Yoshida T, Yoshioka K, et al. (33-adrenoreceptor gene polymorphism: a newly identified risk factor for proliferative retinopathy. Diabetes 46: 1633, 1997.