Enhanced prostaglandin E2 production by monocytes in atopic dermatitis (AD) is not accompanied by enhanced production of IL-6, IL-10 or IL-12

Clinical and Experimental Immunology

Volumn 111, Issue 3, 1998, Pages 472-476

  Snijders, A ^a   Van Der Pouw Kraan, T C T M ^a   Engel, M ^a   Wormmeester, J ^a   Widjaja, P ^b   Zonneveld, I M ^a   Bos, J D ^a   Kapsenberg, M L ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b Allergy Centre Amsterdam East   (Netherlands)

Author keywords

Atopic dermatitis; IL 12; Monocytes; PGE2

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; INTERLEUKIN DERIVATIVE; PROSTAGLANDIN E2;

ADULT; ANTIGEN PRESENTING CELL; ARTICLE; ATOPIC DERMATITIS; BLOOD ANALYSIS; BLOOD CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; HELPER CELL; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; PRIORITY JOURNAL; ADOLESCENT; BIOSYNTHESIS; BLOOD; CELL CULTURE; DRUG EFFECT; FEMALE; LYMPHOCYTE ACTIVATION; MALE; METABOLISM; MIDDLE AGED; MONONUCLEAR CELL; STIMULATION;

ADOLESCENT; ADULT; CELLS, CULTURED; DERMATITIS, ATOPIC; DINOPROSTONE; FEMALE; HUMANS; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-12; INTERLEUKIN-6; INTERLEUKINS; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; STIMULATION, CHEMICAL;

EID: 0032011110     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1998.00516.x     Document Type: Article

References (34)

1. Reinhold U, Wehrmann W, Kukel S, Kreysel HW. Evidence that defective interferon-gamma production in atopic dermatitis patients is due to intrinsic abnormalities. Clin Exp Immunol 1990; 79:374-9.
2. Rousset F, Robert J, Andary M et al. Shifts in interleukin-4 and interferon-gamma production by T cells of patients with elevated serum IgE levels and the modulatory effects of these lymphokines on spontaneous IgE synthesis. J Allergy Clin Immunol 1991; 87:58-69.
3. Jujo K, Renz H, Abe J, Gelfand EW, Leung DYM. Decreased interferon gamma and increased interleukin-4 production in atopic dermatitis promotes IgE synthesis. J Allergy Clin Immunol 1992; 90:323-31.
4. 2 regulation of cytokine production in atopic dermatitis. J Immunol 1993; 151:3345-52.
5. + allergen-specific T lymphocytes in atopic dermatitis lesional skin. J Invest Dermatol 1991; 97:389-94.
6. Wierenga EA, Snoek M, Jansen HM, Bos JD, van Lier RA, Kapsenberg ML. Human atopen-specific types 1 and 2 T helper cell clones. J Immunol 1991; 147:2942-9.
7. Tang MLK, Kemp AS, Thorburn J, Hill DJ. Reduced interferon-gammma secretion in neonates and subsequent atopy. Lancet 1994; 344:983-5.
8. Trinchieri G. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu Rev Immunol 1995; 13:251-76.
9. + T cells through IL-12 produced by Listeria-induced macrophages. Science 1993; 260:547-9.
10. 2 differentially modulates cytokine secretion profiles of human T helper lymphocytes. J Immunol 1993; 150:5321-9.
11. 2 critically depends on interleukin-2. Eur J Immunol 1995; 25:59-63.
12. + T cells inhibits acquisition of ability to produce IFN-gamma and IL-2. but not IL-4 and IL-5. J Immunol 1995; 155:4604-12.
13. + T cells. J Immunol 1946; 156:1722-7.
14. Jakob T, Huspith N, Latchman E, Rycroft R, Brostoff J. Depressed lymphocyte transformation and the role of prostaglandins in atopic dermatitis. Clin Exp Immunol 1990; 79:380-4.
15. 2 is a potent inhibitor of human interleukin 12 production. J Exp Med 1945; 181:775-9.
16. 2. Ann NY Acad Sci 1996; 795:147-57.
17. Snijders A, Hilkens CMU, Van der Pouw Kraan TCTM, Engel M, Aarden LA, Kapsenberg ML. Regulation of bioactive IL-12 production in LPS-stimulated human monocytes is determined by the expression of the p35 subunit. J Immunol 1996; 156:1207-12.
18. Wang P, Wu P, Anthes JC, Siegel MI, Egan RW, Billah MM. Interleukin-10 inhibits interleukin-8 production in human neutrophils. Blood 1994; 83:2678-83.
19. Moore KW, O'Garra A, De Waal Malefyt R, Vieira P, Mosmann TR. Interleukin-10. Annu Rev Immunol 1993; 11:165-90.
20. Saareks V, Riutta A, Mucha I, Alanko J, Vapaatalo H. Nicotine and cotinine modulate eicosanoid production in human leukocytes and platelet rich plasma. Eur J Pharmacol 1993; 248:345-9.
21. Walker TS, Hoover CS. Rickettsial effects on leukotiene and prostaglandin secretion by mouse polymorphonuclear leukocytes. Infect Immun 1991; 59:351-6.
22. Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Dermatol Venereol 1980; 92:44-48.
23. Jansen PM, Van der Pouw Kraan TCTM, De Jong IW et al. Release of interleukin-12 in experimental Escherichia coli septic shock in baboons: relation to plasma levels of interleukin-10 and interferon-gamma. Blood 1996; 87:5144-51.
24. Van der Poll T, Jansen J, Levi M, Ten Cate H, Ten Cate JW, Van Deventer SJH. Regulation of interleukin 10 release by tumor necrosis factor in humans and chimpanzees. J Exp Med 1994; 180:1985-8.
25. Kubin M, Chow JM, Trinchieri G. Differential regulation of interleukin-12 (IL-12). tumor necrosis factor alpha, and IL-1 beta production in human myeloid leukemia cell lines and peripheral blood mononuclear cells. Blood 1994; 83:1847-55.
26. Van der Pouw Kraan TCTM, Boeije LCM, de Groot ER et al. Reduced production of interleukin 12 (IL-12) and IL-12-dependant IFN-gamma release by allergic asthma patients. J Immunol 1997; 158:5560-5.
27. Lester MR, Hofer MF, Gately M, Trumble A, Leung DY. Down-regulating effects of IL-4 and IL-10 on the IFN-gamma response in atopic dermatitis. J Immunol 1995; 154:6174-81.
28. Ohmen JD, Hanifin JM, Nickoloff BJ et al. Overexpression of IL-10 in atopic dermatitis: contrasting cytokine patterns with delayed-type hypersensitivity reactions. J Immunol 1995; 154:1956-63.
29. 2 and leukotrienes B4 and C4 from leukocytes of patients with atopic eczema. Acta Dermatol Venereol 1987; 67:469-75.
30. Jakob T, Neuber K, Ring J. Decreased monocyte interleukin-1β production in atopic eczema. Br J Dermatol 1995; 132:384-90.
31. Hla T, Neilson K. Human cyclooxygenuse-2 cDNA. Proc Natl Acad Sci USA 1992; 89:7384-8.
32. Mertz PM, DeWitt DL, Stetler-Stevenson WG, Wahl LM. Interleukin 10 suppression of monocyte prostaglandin H synthase-2. Mechanism of inhibition of prostaglandin-dependent matrix metalloproteinase production. J Biol Chem 1994; 269:21322-9.
33. Lee SH, Soyoola E, Chanmugam P et al. Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide. J Biol Chem 1992; 267:25934-8.
34. 2 by monocytes of newborns is due to altered fatty acid membrane content and reduced cyclooxygenase activity. J Immunol 1996; 157:3116-21.