A phase 1 study of the transplantation of genetically marked autologous bone marrow stromal cells

Human Gene Therapy

Volumn 9, Issue 4, 1998, Pages 591-600

  Keating, Armand ^a   Berkahn, Leanne ^a   Filshie, Robin ^a  

^a UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; BONE MARROW CULTURE; CELL MEDIATED CYTOTOXICITY; CELL VIABILITY; CLINICAL TRIAL; GENE THERAPY; GENETIC MARKER; HEMATOPOIESIS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PHASE 1 CLINICAL TRIAL; STROMA CELL; BLOOD DISEASE; BONE MARROW TRANSPLANTATION; BREAST TUMOR; CLINICAL PROTOCOL; METHODOLOGY; TRANSPLANTATION;

ANIMALIA;

BONE MARROW TRANSPLANTATION; BREAST NEOPLASMS; CLINICAL PROTOCOLS; CLINICAL TRIALS, PHASE I; GENE THERAPY; HEMATOLOGIC NEOPLASMS; HUMANS; STROMAL CELLS;

EID: 0032008525     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1998.9.4-591     Document Type: Article

References (6)

1. ANDERSON, D.M., LYMAN, S.D., BAIRD, A., WIGNALL, J.M., EISENMAN, J., RAUCH, C., MARCH, C.J., BOSWELL, S., GIMPEL, S.D., COSMAN, D. and WILLIAMS, D.E. (1990). Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms. Cell 63, 235-243.
2. ANKLESARIA, P., KASE, K., GLOWACKI, J., HOLLAND, C.A., SAKAKEENY, M.A., WRIGHT, J.A., FITZGERALD, T.J., LEE, C.-Y. and GREENBERGER, J.S. (1987). Engraftment of a clonal bone marrow strornal cell line in vivo stimulates hematopoietic recovery from total body irradiation. Proc. Natl. Acad. Sci. USA 84, 7681-7685.
3. BARNETT, M.J., EAVES, C.J., PHILLIPS, G.L., GASCOYNE, R.D., HOGGE, D.E., HORSMAN, D.E., HUMPHRIES, R.K., KLINGEMANN, H.-G., LANSDORP, P.M., NANTEL, S.H., REECE, D.E., SHEPHERD, J.D., SPINELLI, J.J., SUTHERLAND, H.J. and EAVES, A.C. (1994). Autografting with cultured marrow in chronic myeloid leukemia: results of a pilot study. Blood 84, 724-732.
4. CAPLEN, N.J., GAO, X., HAYES, P., ELASWARAPU, R., FISHER, G., KINRADE, E., CHAKERA, A., SCHORR, J., HUGHES, B., DORIN, J.R., PORTEOUS, D.J., ALTON, E.W.F.W., GEDDES, E.M., COUTELLE, C., WILLIAMSON, L.H. and GILCHRIST, C. (1994). Gene therapy for cystic fibrosis in humans by liposome-mediated DNA transfer: The production of resources and regulatory process. Gene Ther 1, 139-147.
5. CASHMAN, J., EAVES, A.C. and EAVES, C.J. (1985). Regulated proliferation of primitive hematopoietic progenitor cells in long-term human marrow cultures. Blood 66, 1002-1005.
6. CHANG, J., ALLEN, T.D. and DEXTER, T.M. (1990). Long-term bone marrow cultures: Their use in autologous bone marrow transplantation. Cancer Cells 1, 17-24.