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Volumn 159, Issue 1, 1998, Pages 107-112

Mutational analysis of the role of the conserved lysine-270 in the Pichia stipitis xylose reductase

Author keywords

Coenzyme binding; Lysine; Pichia stipitis; Site directed mutagenesis; Xylose reductase; Yeast

Indexed keywords

LYSINE; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG; XYLITOL; XYLOSE; XYLOSE REDUCTASE;

EID: 0032008240     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(97)00555-7     Document Type: Article
Times cited : (57)

References (21)
  • 1
    • 0025550179 scopus 로고
    • Regulation of D-xylose utilization by hexoses in pentose-fermenting yeasts
    • Webb, S.R. and Lee, H. (1990) Regulation of D-xylose utilization by hexoses in pentose-fermenting yeasts. Biotechnol. Adv. 9, 685-697.
    • (1990) Biotechnol. Adv. , vol.9 , pp. 685-697
    • Webb, S.R.1    Lee, H.2
  • 2
    • 0026475568 scopus 로고
    • Aldose reductase: model for a new paradigm of enzymic perfection in detoxification catalysis
    • Grimshaw, C.E. (1992) Aldose reductase: model for a new paradigm of enzymic perfection in detoxification catalysis. Biochemistry 31, 10139-10145.
    • (1992) Biochemistry , vol.31 , pp. 10139-10145
    • Grimshaw, C.E.1
  • 3
    • 0029003606 scopus 로고
    • Aldose reductase as a target for drug design: molecular modelling calculations on the binding of acyclic sugar substrates to the enzyme
    • De Winter, H.L. and von Itzstein, M. (1995) Aldose reductase as a target for drug design: molecular modelling calculations on the binding of acyclic sugar substrates to the enzyme. Biochemistry 34, 8299-8308.
    • (1995) Biochemistry , vol.34 , pp. 8299-8308
    • De Winter, H.L.1    Von Itzstein, M.2
  • 4
    • 0000551699 scopus 로고
    • Inhibitors of xylose reductase from the yeast Pichia stipitis
    • Webb, S.R. and Lee, H. (1991) Inhibitors of xylose reductase from the yeast Pichia stipitis. Appl. Biochem. Biotechnol. 30, 325-337.
    • (1991) Appl. Biochem. Biotechnol. , vol.30 , pp. 325-337
    • Webb, S.R.1    Lee, H.2
  • 6
    • 0024436674 scopus 로고
    • Physiological properties of a mutant of Pachysolen tannophilus deficient in NADPH-dependent D-xylose reductase
    • Schneider, H., Lee, H., Barbosa, M. de F.S., Kubicek, C.P. and James, A.P. (1989) Physiological properties of a mutant of Pachysolen tannophilus deficient in NADPH-dependent D-xylose reductase. Appl. Environ. Microbiol. 55, 2877-2881.
    • (1989) Appl. Environ. Microbiol. , vol.55 , pp. 2877-2881
    • Schneider, H.1    Lee, H.2    Barbosa, M.3    De, F.S.4    Kubicek, C.P.5    James, A.P.6
  • 10
    • 0029417316 scopus 로고
    • Cloning and sequencing of two D-xylose reductase genes (xyrA and xyrB) from Candida tropicalis
    • Yokoyama, S., Kinoshita, Y., Suzuki, T., Kawai, K., Horitsu, H. and Takamizawa, K. (1995) Cloning and sequencing of two D-xylose reductase genes (xyrA and xyrB) from Candida tropicalis. J. Ferment. Bioeng. 80, 603-605.
    • (1995) J. Ferment. Bioeng. , vol.80 , pp. 603-605
    • Yokoyama, S.1    Kinoshita, Y.2    Suzuki, T.3    Kawai, K.4    Horitsu, H.5    Takamizawa, K.6
  • 11
    • 0029160251 scopus 로고
    • Isolation and characterization of the gene encoding xylose reductase from Kluyveromyces lactis
    • Billard, P., Menart, S., Fleer, R. and Bolotin-Fukuhara, M. (1995) Isolation and characterization of the gene encoding xylose reductase from Kluyveromyces lactis. Gene 162, 93-97.
    • (1995) Gene , vol.162 , pp. 93-97
    • Billard, P.1    Menart, S.2    Fleer, R.3    Bolotin-Fukuhara, M.4
  • 12
    • 0029853042 scopus 로고    scopus 로고
    • Sequence and analysis of aldose (xylose) reductase gene from the xylose-fermenting yeast Pachysolen tannophilus
    • Bolen, P.L., Hayman, G.T. and Shepherd, H.S. (1996) Sequence and analysis of aldose (xylose) reductase gene from the xylose-fermenting yeast Pachysolen tannophilus. Yeast 12, 1367-1375.
    • (1996) Yeast , vol.12 , pp. 1367-1375
    • Bolen, P.L.1    Hayman, G.T.2    Shepherd, H.S.3
  • 13
    • 0026782585 scopus 로고
    • Characterization of xylose reductase from the yeast Pichia stipitis: evidence for functional thiol and histidyl groups
    • Webb, S.R. and Lee, H. (1992) Characterization of xylose reductase from the yeast Pichia stipitis: evidence for functional thiol and histidyl groups. J. Gen. Microbiol. 138, 1857-1863.
    • (1992) J. Gen. Microbiol. , vol.138 , pp. 1857-1863
    • Webb, S.R.1    Lee, H.2
  • 14
    • 0031050344 scopus 로고    scopus 로고
    • Site-directed mutagenesis of the cysteine residue in the Pichia stipitis xylose reductase
    • Zhang, Y. and Lee, H. (1997) Site-directed mutagenesis of the cysteine residue in the Pichia stipitis xylose reductase. FEMS Microbiol. Lett. 147, 227-232.
    • (1997) FEMS Microbiol. Lett. , vol.147 , pp. 227-232
    • Zhang, Y.1    Lee, H.2
  • 15
    • 0024552846 scopus 로고
    • Aldose reductase from human psoas muscle: affinity labeling of an active site lysine by pyridoxal 5′-phosphate and pyridoxal 5′-diphospho-5′-adenosine
    • Morjana, N.A., Lyons, C. and Flynn, T.G. (1989) Aldose reductase from human psoas muscle: affinity labeling of an active site lysine by pyridoxal 5′-phosphate and pyridoxal 5′-diphospho-5′-adenosine. J. Biol. Chem. 264, 2912-2919.
    • (1989) J. Biol. Chem. , vol.264 , pp. 2912-2919
    • Morjana, N.A.1    Lyons, C.2    Flynn, T.G.3
  • 16
    • 0026344829 scopus 로고
    • Expression of human aldose and aldehyde reductases: site-directed mutagenesis of a critical lysine 262
    • Bohren K.M., Page, J.L., Shankar, R., Henry, S.P. and Gabbay, K.H. (1991) Expression of human aldose and aldehyde reductases: site-directed mutagenesis of a critical lysine 262. J. Biol. Chem. 266, 24031-24037.
    • (1991) J. Biol. Chem. , vol.266 , pp. 24031-24037
    • Bohren, K.M.1    Page, J.L.2    Shankar, R.3    Henry, S.P.4    Gabbay, K.H.5
  • 17
    • 0026719692 scopus 로고
    • An unlikely sugar substrate site in the 1.65 Å structure of the human aldose reductase holoenzyme implicated in diabetic complications
    • Wilson, D.K., Bohren, K.M., Gabbay, K.H. and Quiocho F.A. (1992) An unlikely sugar substrate site in the 1.65 Å structure of the human aldose reductase holoenzyme implicated in diabetic complications. Science 257, 81-84.
    • (1992) Science , vol.257 , pp. 81-84
    • Wilson, D.K.1    Bohren, K.M.2    Gabbay, K.H.3    Quiocho, F.A.4
  • 18
    • 0030571272 scopus 로고    scopus 로고
    • Continuous enzymatic production of xylitol with simultaneous coenzyme regeneration in a charged membrane reactor
    • Nidetzky, B., Neuhauser, W., Haltrich, D. and Kulbe, K.D. (1996) Continuous enzymatic production of xylitol with simultaneous coenzyme regeneration in a charged membrane reactor. Biotechnol. Bioeng. 52, 387-396.
    • (1996) Biotechnol. Bioeng. , vol.52 , pp. 387-396
    • Nidetzky, B.1    Neuhauser, W.2    Haltrich, D.3    Kulbe, K.D.4
  • 19
    • 0021959310 scopus 로고
    • Properties of the NAD(P)H-dependent xylose reductase from the xylose fermenting yeast Pichia stipitis
    • Verduyn, C., van Kleef, R., Frank, J., Schreuder, H., van Dijken, J.P. and Scheffers, W.A. (1985) Properties of the NAD(P)H-dependent xylose reductase from the xylose fermenting yeast Pichia stipitis. Biochem. J. 226, 669-677.
    • (1985) Biochem. J. , vol.226 , pp. 669-677
    • Verduyn, C.1    Van Kleef, R.2    Frank, J.3    Schreuder, H.4    Van Dijken, J.P.5    Scheffers, W.A.6
  • 20
    • 0025887633 scopus 로고
    • Mechanism of adenylate kinase: site-directed mutagenesis versus X-ray and NMR
    • Tsai, M.D. and Yan, H. (1991) Mechanism of adenylate kinase: site-directed mutagenesis versus X-ray and NMR. Biochemistry 30, 6806-6818.
    • (1991) Biochemistry , vol.30 , pp. 6806-6818
    • Tsai, M.D.1    Yan, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.