Identification of a novel ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11-q12

Genomics

Volumn 47, Issue 3, 1998, Pages 383-392

  Nothwang, Hans Gerd ^a,b   Rensing, Cornelia ^a   Kübler, Matthias ^a   Denich, Dagmar ^a   Brandl, Birgit ^b   Stubanus, Mike ^a   Haaf, Thomas ^b   Kurnit, David ^c   Hildebrandt, Friedhelm ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; RAN BINDING PROTEIN 2; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CHROMOSOME 2Q; GENE CLUSTER; GENE DUPLICATION; GENE LOCATION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DETERMINATION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

EID: 0032006861     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1997.5119     Document Type: Article

References (32)

1. Ballabio A. The rise and fall of positional cloning? Nat. Genet. 3:1993;277-279.
2. Bischoff F. R., Ponstingl H. Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1. Nature. 354:1991;80-82.
3. Bischoff F. R., Krebber H., Kempf T., Hermes I., Ponstingl H. Human RanGTPase-activating protein RanGAP1 is a homologue of yeast Rna1p involved in mRNA processing and transport. Proc. Natl. Acad. Sci. USA. 92:1995;1749-1753.
4. Chi N. C., Adam E. J., Visser G. D., Adam S. A. RanBP1 stabilizes the interaction of Ran with p97 nuclear protein import. J. Cell Biol. 135:1996;559-569.
5. Chowdhury K. One step "miniprep" method for the isolation of plasmid DNA. Nucleic Acids Res. 19:1991;2729.
6. Cohen D., Chumakov I., Weissenbach J. A first-generation physical map of the human genome. Nature. 366:1993;698-701.
7. Ferreira P. A., Nakayama T. A., Pak W. L., Travis G. H. Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin. Nature. 383:1996;637-640.
8. Ferreira P. A., Nakayama T. A., Travis G. H. Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2. Proc. Natl. Acad. Sci. USA. 94:1997;1556-1561.
9. Graninger W. B., Goldman P. L., Morton C. C., O'Brien S. J., Korsmeyer S. J. The K-deleting element: Germline and rearranged, duplicated and dispersed forms. J. Exp. Med. 167:1988;488-501.
10. Haaf T., Bray-Ward P. Region-specific YAC banding and painting probes for comparative genome mapping: Implications for the evolution of human chromosome 2. Chromosoma. 104:1996;537-544.
11. Hayashi N., Yokoyama N., Seki T., Azuma Y., Ohba T., Nishimoto T. RanBP1, a Ras-like nuclear G protein binding to Ran/TC4, inhibits RCC1 via Ran/TC4. Mol. Gen. Genet. 247:1995;661-669.
12. Hildebrandt F., Cybulla M., Strahm B., Nothwang H. G., Singh-Sawhney I., Berz K., Nicklin M., Reiner O., Brandis M. Physical mapping of the gene for juvenile nephronophthisis (NPH1) by construction of a complete YAC contig of 7 Mb on chromosome 2q13. Cytogenet. Cell Genet. 73:1996;235-239.
13. Koepp D. M., Silver P. A. A GTPase controlling nuclear trafficking: Running the right way or walking RANdomly? Cell. 87:1996;1-4.
14. Konrad M., Saunier S., Silbermann F., Benessy F., Le Paslier D., Weissenbach J., Broyers M., Gubler M. C., Antignac C. A 11 Mb YAC contig spanning the familial juvenile nephronophthisis region (NPH1) located on chromosome 2q. Genomics. 30:1995;514-520.
15. Konrad M., Saunier S., Heidet L., Silbermann F., Benessy F., Calado J., Le Paslier D., Broyers M., Gubler M. C., Antignac C. Large homozygous deletions of the 2q13 region are a major cause of juvenile nephronophthisis. Hum. Mol. Genet. 5:1996;367-371.
16. Krebber H., Bastians H., Hoheisel J., Lichter P., Ponstingl H., Joos S. Localization of the gene encoding the Ran-binding protein RanBP2 to human chromosome 2q11-q13 by fluorescencein situ. Genomics. 43:1997;247-248.
17. Kurnit D. M., Cheng J.-F., Zhu Y., Van Keuren M. L., Jiang Y., Pan Y.-Z., Withley K. Transcription patterns of sequences on human chromosome 21. Cytogenet. Cell Genet. 71:1995;203-206.
18. Lautner-Rieske A., Hameister H., Barbi G., Zachau H. G. Mapping immunoglobulin gene-related DNA probes to the central region of normal and pericentrically inverted human chromosome 2. Genomics. 16:1992;497-502.
19. Lounsbury K., Beddow A., Macara I. A family of proteins that stabilize the Ran/TC4 GTPase in its GTP-bound conformation. J. Biol. Chem. 269:1994;11285-11290.
20. Meindl A., Dry K., Herrmann K., Manson F., Ciccodicola A., Edgar A., Carvalho M. R., Achatz H., Hellebrand H., Lennon A., Migliaccio C., Porter K., Zrenner E., Bird A., Jay M., Lorenz B., Wittwer B., D'Urso M., Meitinger T., Wright A. A gene (RPGR) with homology to the RCC1 guanine nucleotide exchange factor is mutated in X-linked retinitis pigmentosa (RP3). Nat. Genet. 13:1996;35-42.
21. Medhioub M., Cherif D., Benessy F., Silbermann F., Gubler M. C., LePaslier D., Cohen D. Refined mapping of a gene (NPH1) causing familial juvenile nephronophthisis and evidence for genetic heterogeneity. Genomics. 22:1994;296-301.
22. Melchior F., Guan T., Yokoyama N., Nishimoto T., Gerace L. GTP hydrolysis by Ran occurs at the nuclear pore complex in an early step of protein import. J. Cell Biol. 131:1995;571-581.
23. Nothwang H. G., Strahm B., Denich D., Kübler M., Schwabe J., Gingrich J. C., Cox A., Nicklin M., Kurnit D. M., Hildebrandt F. Molecular Cloning of the interleukin-1 gene cluster: Construction of an integrated YAC, PAC and partial transcriptional map in the region of chromosome 2q13. Genomics. 41:1997;370-378.
24. Olson M., Hood L., Cantor C., Botstein D. A common language for physical mapping of the human genome. Science. 245:1989;1434-1435.
25. Roepman R., Vanduijnhoven G., Rosenberg T., Pinckers A. J. L. G., Bleeker-Wagemakers L. M., Bergen A. A. B., Post J., Beck A., Reinhardt R., Ropers H. H., Cremers F. P. M., Berger W. Positional cloning of the gene for X-linked retinitis pigmentosa 3 - Homology with the guanine-nucleotide-exchange factor RCC1. Hum. Mol. Genet. 5:1996;1035-1041.
26. Rush M. G., Drivas G., D'Eustachio P. The small nuclear GTPase Ran: How much does it run? BioEssays. 18:1996;103-112.
27. Saitoh H., Cooke C. A., Burgess W. H., Earnshaw W. C., Dasso M. Direct and indirect asociation of the small GTPase Ran with nuclear pore proteins and soluble transport factors - Studies inXenopus laevis. Mol. Cell. Biol. 7:1996;1319-1334.
28. Smith R. F., Wiese B. A., Wojzynski M. K., Davison D. B., Worley K. C. BCM search launcher - An integrated interface to molecular biology data base search and analysis services available on the world wide web. Genome Res. 6:1996;454-462.
29. Ward D. C., Boyle A., Haaf T. Fluorescence in situ hybridization techniques. Metaphase chromosomes, interphase nuclei, and extended chromatin fibers. Human Chromosomes. Principles and Techniques. 1995;McGraw-Hill, New York. p. 184-192.
30. Wilken N., Senecal J. L., Scheer U., Dabauvalle M. C. Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex. Eur. J. Cell Biol. 68:1995;211-219.
31. Wu J., Matunis M. J., Kraemer D., Blobel G., Coutavas E. Nup358, a cytoplasmically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich region. J. Biol. Chem. 270:1995;14209-14213.
32. Yokoyama N., Hayashi N., Seki T., Pante N., Ohba T., Nishii K., Hayashida T., Miyata T., Aebi U., Fukui M., Nishimoto T. A giant nucleopore protein that binds Ran/TC4. Nature. 376:1995;184-188.