Chronic myeloid Leukemia with thrombocythemic onset may be associated with different BCR/ABL variant transcripts

Cancer Genetics and Cytogenetics

Volumn 101, Issue 1, 1998, Pages 75-77

  Emilia, G ^a,c   Luppi, M ^a   Ferrari, M G ^a   Temperani, P ^a   Marasca, R ^a   Giacobbi, F ^a   Vaccari, P ^a   Bandieri, E ^b   Di Donato, C ^b   Carapezzi, C ^b   Torelli, G ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b Ospedale Ramazzini   (Italy)

^c UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ANAGRELIDE; BUSULFAN; HYDROXYUREA; INTERFERON; MESSENGER RNA; TIOGUANINE; URAMUSTINE;

ADULT; AGED; ARTICLE; BLOOD CELL COUNT; CHROMOSOME ANALYSIS; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN CELL; LEUKOCYTOSIS; MALE; ONCOGENE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THROMBOCYTE COUNT; THROMBOCYTHEMIA;

ADULT; AGED; FEMALE; FUSION PROTEINS, BCR-ABL; HUMANS; LEUKEMIA, MYELOID, PHILADELPHIA-POSITIVE; MALE; MIDDLE AGED; PHENOTYPE; RNA, MESSENGER; THROMBOCYTOSIS; TRANSLOCATION, GENETIC;

EID: 0032006324     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-4608(97)00263-X     Document Type: Article

References (11)

1. Shtivelmann E, Lifshitz B, Gale RP, Canaani E (1985): Fused transcript of abl and bcr genes in chronic myelogenous leukaemia. Nature 315:550-553.
2. Saglio G, Guerrasio A, Rosso C, Zaccaria A, Tassinari A, Serra A, Rege-Cambrin G, Mazza U, Gavosto F (1990): New type of Bcr/Abl junction in Philadelphia chromosome-positive chronic myelogenous leukemia. Blood 76:1819-1824.
3. Wada H, Mizutani S, Nishimura J, Usuki Y, Kohsaki M, Komai M, Keneko H, Sakamoto S, Delia D, Kanamaru A, Kakishita E (1995): Establishment and molecular characterization of a novel leukemic cell line with Philadelphia chromosome expressing p230 BCR/ABL fusion protein. Cancer Res 55:3192-3196.
4. Yamagata T, Mitani K, Kanada Y, Yazaki Y, Hirai H (1996): Elevated platelet count features the variant type of BCR/ABL junction in chronic myelogenous leukaemia. Br J Haematol 94:370-372.
5. Pane F, Frigeri F, Sindona M, Luciano L, Ferrara F, Cimino R, Meloni G, Saglio G, Salvatore F, Rotoli B (1996): Neutrophilic-chronic myeloid leukemia: a distinct disease with a specific molecular marker (BCR/ABL with C3/A2 junction). Blood 88:2410-2414.
6. Martiat P, Ifrah B, Rassool F, Morgan G, Giles F, Gow J, Goldman JM (1989): Molecular analysis of Philadelphia positive essential thrombocythemia. Leukemia 3:563-565.
7. Inokuchi K, Nomura T (1993): The relationship between the type of bcr/abl hybrid messenger RNA and thrombopoiesis in Philadelphia-positive chronic myelogenous leukemia. Leuk Lymph 10:9-15.
8. Kwong YL, Chiu EKW, Liang RHS, Chan V, Chan TK (1996): Essential thrombocythemia with BCR/ABL rearrangement. Cancer Genet Cytogenet 89:74-76.
9. Cervantes F, Colomer D, Vives-Corrons JL, Rozman C, Monserrat E (1996): Chronic myeloid leukemia of thrombocythemic onset: a CML subtype with distinct hematological and molecular features? Leukemia 10:1241-1243.
10. Borrow J, Goddard AD, Gibbons B, Katz F, Swirsky D, Fioretos T, Winfield DA, Kingston J, Hagemeijer A, Rees JKH, Lister TA, Solomon E (1992): Diagnosis of acute promyelocytic leukemia by RT-PCR: detection of PML-RARα and RARα-PML fusion transcripts. Br J Haematol 82:529-540.
11. Bornstein R, Lahuerta-Palacios JJ (1990): Does the Philadelphia chromosome exclude the diagnosis of essential thrombocythemia? Am J Hematol 35:70-71.