Dissociation between startle and prepulse inhibition in rats exposed to γ radiation at day 15 of embryogeny

Brain Research Bulletin

Volumn 45, Issue 3, 1998, Pages 289-296

  Mintz, M ^a   Yovel, G ^a   Gigi, A ^a   Myslobodsky, M S ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Amphetamine; Habituation; Postnatal; Prenatal; Prepulse inhibition; PTSD; Radiation; Rats; Startle; Stress

Indexed keywords

AMPHETAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; EMBRYO DEVELOPMENT; HABITUATION; MYOCLONUS; NERVE CELL DIFFERENTIATION; NONHUMAN; POSTTRAUMATIC STRESS DISORDER; PREPULSE INHIBITION; PRIORITY JOURNAL; RADIATION EXPOSURE; RAT; SENSORY STIMULATION; STARTLE REFLEX; STIMULUS RESPONSE; STRESS; WHOLE BODY RADIATION;

ACOUSTIC STIMULATION; ANIMALS; FEMALE; GAMMA RAYS; NEURAL INHIBITION; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PSYCHOACOUSTICS; RATS; RATS, SPRAGUE-DAWLEY; SEXUAL MATURATION; STARTLE REACTION;

EID: 0032006196     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(97)00373-0     Document Type: Article

References (58)

1. Abrams D. R., Bruno J. P. Ontogeny of apomorphine-induced stereotypy and its D1 and D2 receptor mediation in rats depleted of dopamine as neonates. Dev. Psychobiol. 25:1992;475-495.
2. Altman J., Das G. Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. J. Comp. Neurol. 124:1965;319-336.
3. Altman J., Bayer S. A. Mosaic organization of the hippocampal neuroepitelium and the multiple germinal sources of dentate granule cells. J. Comp. Neurol. 301:1969;325-342.
4. Andermann F., Andermann E. Hyperekplexia, jumping, and startle epilepsy. Brain Dev. 10:1988;213-222.
5. Angevine, Jr. J. B. Critical cellular events in the shaping of neural centers. In: Schmitt, F. O., eds. The second neurosciences program. Cambridge: The MIT Press; 1974:62-71.
6. Bayer S. A. Neurogenesis in the rat amygdala. Ben-Ari Y. The amygdaloid complex. 1981;19-31 Elsevier, Amsterdam.
7. Blanchard R. J., Blanchard D. C. Effects of hippocampal lesions on the rat's reaction to a cat. J. Comp. Physiol. Psychol. 78:1972;77-82.
8. Bolino F., Manna V., DiCicco L. Startle reflex habituation in functional psychoses a controlled study . Neurosci. Lett. 145:1992;126-128.
9. Braff D. L., Stone C., Callaway E., Geyer M. A., Glick I. D., Bali L. Prestimulus effects on human startle reflex in normals and schizophrenics. Psychophysiology. 15:1978;339-343.
10. Braff D. L., Geyer M. A. Sensorimotor gating and schizophrenia. Arch. Gen. Psych. 47:1990;181-188.
11. Braff D. L., Grillon C., Geyer M. A. Gating and habituation of the startle reflex in schizophrenic patients. Arch. Gen. Psychiatry. 49:1992;206-215.
12. Buelke-Sam J., Kimmel C. A., Adams J., Nelson C. J., Reiter L. W., Sobotka T. J., Tilson H. A., Nelson B. K. Collaborative behavioral teratology study Results . Neurobehav. Toxicol. Teratol. 7:1985;591-624.
13. Butler R. W., Braff D. L., Rausch J. L., Jenkins M. A., Sprock J., Geyer M. A. Physiological evidence of exaggerated startle response in the subgroup of Vietnam veterans with combat-related PTSD. Am. J. Psychiatry. 147:1990;1308-1312.
14. Castaneda E., Whishaw I. Q., Lermer L., Robinson T. E. Dopamine depletion in neonatal rats Effects on behavior and striatal dopamine release assessed by intracerebral microdialysis during adulthood . Brain Res. 508:1990;30-39.
15. Dahl S. Acute response to rape - a PTSD variant. Acta. Psychiatr. Scand. Suppl. 355:1989;56-62.
16. Davis M., Gendelman D. S., Tischler M. D., Gendelman P. M. A primary acoustic startle circuit Lesion and stimulation studies . J. Neurosci. 6:1982;791-805.
17. Donoso J. A., Norton S. The pyramidal neuron in cerebral cortex following prenatal X irradiation. Neurotoxicology. 3:1982;72-84.
18. Furchgott E., Tacker R. S., Draper D. O. Open-field behavior and heart rate in prenatally X irradiated rats. Physiol. Behav. 16:1968;441-452.
19. Geyer M. A., Braff D. L. Habituation of the blink reflex in normals and schizophrenic patients. Psychophysiology. 19:1982;1-6.
20. Geyer M. A., Butcher R. E., Fite K. A study of startle and locomotor activity in rats exposed prenatally in methylmercury. Neurobehav. Toxicol. Teratol. 7:1985;483-488.
21. Geyer M. A., Braff D. L. Startle habituation and sensorimotor gating in schizophrenia and related animal models. Schizophr. Bull. 13:1987;643-668.
22. Hammond G. R. Frontal cortical lesions and prestimulus inhibition of the rat's acoustic startle reaction. Physiol. Psychol. 2:1974;151-156.
23. Hicks S. P., D'Amato C. J. Effects of ionizing radiation on developing brain and behavior. Gottlieb G. Studies on the development of behavior and the nervous system. Vol. 4 Early influences . 1978;35-72 Academic Press, London.
24. Hicks S. P., D'Amato C. J. Developmental of the motor system Hopping rats produced by prenatal irradiation . Exp. Neurol. 70:1980;24-39.
25. Huether G., Kaus R., Neuhoff V. Amino acid depletion in the blood and brain tissue of hyperphenylalaninemic rats is abolished by the administration of additional lysine A contribution to the understanding of the metabolic defects in phyenylketonuria . Biochem. Med. 33:1985;334-341.
26. Kimler B. F., Norton S. Behavioral changes and structural defects in rats irradiated in utero. Int. J. Radiat. Oncol. Biol. Phys. 15:1988;1171-1177.
27. Koch M. Microinjections of the metabotropic glutamate receptor agonist, trans-(+/-)-1-amino-cyclopentane-1,3-dicarboxylate (trans-ACPD) into the amygdala increase the acoustic startle response of rats. Brain Res. 629:1993;176-179.
28. Koch M., Elbert U. Enhancement of the acoustic startle response by stimulation of an excitatory pathway from the central amygdala/basal nucleus of Meynert to the pontine reticular formation. Exp. Brain Res. 93:1993;231-241.
29. Lauder J. M., Bloom F. E. Ontogeny of monoamine neurons in the locus coeruleus, raphe nuclei and substantia nigra of the rat. I Cell differentiation . J. Comp. Neurol. 155:1974;469-482.
30. LeDoux J. E. Emotion and the amygdala. Aggleton J. P. The Amygdala. 1992;339-351 Wiley-Liss, New York.
31. Lipska B. K., Swerdlow N. R., Geyer M. A., Jaskiw G. E., Braff D. L., Weinberger D. R. Neonatal excitotoxic hippocampal damage in rats causes post-pubertal changes in prepulse inhibition of startle and its disruption by apomorphine. Psychopharmacology. 122:1995;35-43.
32. Loughrey G. C., Bell P., Kee M., Roddy D. J., Curran P. S. Post-traumatic stress disorder and civil violence in Northern Ireland. Br. J. Psychiatry. 153:1988;554-560.
33. Mansbach R. S., Geyer M. A., Braff D. L. Dopaminergic stimulation disrupts sensorimotor gating in the rat. Psychopharmacology. 94:1988;507-514.
34. McGhie A., Chapman J. Disorders of attention and perception in early schizophrenia. Br. J. Med. Psychol. 34:1961;103-116.
35. Mintz, M.; Gigi, A.; Shohami, D.; Myslobodsky, M. S. Effects of prenatal exposure to γ rays on activity and circling behavior in prepubertal and postpubertal rats. Behav. Brain Res. submitted.
36. Myslobodsky M. Petit Mal Epilepsy A search for precursors of petit mal activity . 1976;Academic Press, New York.
37. Myslobodsky M. S., Glicksohn J., Singer J., Stern M., Bar-Ziv J., Friedland N., Bleich A. Changes of brain anatomy in patients with posttraumatic stress disorder A pilot magnetic resonance imaging study . Psychiatry Res. Imaging. 58:1995;259-264.
38. Nash D. J., Gowen J. W. Effects of x irradiation upon postnatal growth in the mouse. Biol. Bull. 122:1962;115-136.
39. Norton S., Kimler B. F., Mullenix P. J. Progressive behavioral changes in rat after exposure to low levels of ionizing radiation in utero. Neurotoxicol. Teratol. 13:1991;181-188.
40. Paxinos G., Tork I., Tecott L. H., Valentino K. L. Atlas of the developing rat brain. 1991;Academic Press, San Diego.
41. Orr S. P., Lasko N. B., Shalev A. Y., Pitman R. K. Physiologic responses to loud tones in Vietnam veterans with posttraumatic stress disorder. J. Abnorm. Psychol. 104:1995;75-82.
42. Robinson T. E., Becker J. B., Young E. A., Akil H., Castaneda E. The effects of footshock stress on regional brain dopamine metabolism and pituitary beta-endorphin release in rats previously sensitized to amphetamine. Eur. Pharmacol. 26:1987;679-691.
43. Rosen J. B., Davis M. Enhancement of acoustic startle by electrical stimulation of the amygdala. Behav. Neurosci. 102:1988;195-202.
44. Schwarzkopf S. B., Mitra T., Bruno J. P. Sensory gating in rats depleted of dopamine as neonates potential relevance to findings in schizophrenic patients . Biol. Psychiatry. 31:1992;759-773.
45. Schwarzkopf S. B., Lamberti J. S., Smith D. A. Concurrent assessment of acoustic startle and auditory P50 evoked potential measures of sensory inhibition. Biol. Psychiatry. 33:1993;815-828.
46. Shalev A. Y., Orr S. P., Peri T., Schreiber S., Pitman R. K. Physiologic responses to loud tones in Israeli patients with posttraumatic stress disorder. Arch. Gen. Psychiatry. 49:1992;870-874.
47. Shore J. H., Tatum E. L., Vollmer W. M. Psychiatric reactions to disaster The Mount St. Helens experience . Am. J. Psychiatry. 143:1986;590-595.
48. Shore J. H., Tatum E. L. Community patterns of posttraumatic stress disorders. J. Nerv. Ment. Dis. 177:1989;681-695.
49. Stricker E. M., Zigmond M. J. Effects of homeostasis of intraventricular injections of 6-hydroxydopamine in rats. J. Comp. Physiol. Psychol. 86:1974;973-994.
50. Swerdlow N. R., Lipska B. K., Weinberger D. R., Braff D. L., Jaskiw G. E., Geyer M. A. Increased sensitivity to sensorimotor gating-disruptive effects of apomorphine after lesions of medial prefrontal cortex or ventral hippocampus in adult rats. Psychopharmacology. 122:1995;27-34.
51. Tauber E. Histogenesis of brain stem neurons studied autoradiographically with 3H-thymidine in the mouse. Anat. Rec. 145:1963;291-301.
52. Vand der Staak C., Fischer W. Habituation to intense acoustic stimulation during cortical spreading depression in rats. Physiol. Behav. 16:1976;681-687.
53. Vorhees C. V., Ahrens K. G., Acuff-Smith K. D., Schilling M. A., Fisher J. E. Metamphetamine exposure during early postnatal development in rats: I Acoustic startle augmentation and spatial learning deficits . Psychopharmacology. 114:1994a;392-401.
54. Vorhees C. V., Ahrens K. G., Acuff-Smith K. D., Schilling M. A., Fisher J. E. Metamphetamine exposure during early postnatal development in rats: 2 Hypoactivity and altered responses to pharmacological challenge . Psychopharmacology. 114:1994b;402-408.
55. Uylings, H. B. M.; Van Eden, C. G.; Parnavelas, J. G.; Kalsbeek, A. The prenatal and postnatal development of rat cerebral cortex. In: Kolb, B.; Tees, R. C.; eds. The cerebral cortex of the rat. Cambridge: A Bradford Book, The MIT Press; 1990: 35-76.
56. Werboff J., Broeder D., Havlena J., Sikov M. Effects of prenatal × irradiation on audiogenic seizures in the rat. Exp. Neurol. 31:1961;189-196.
57. Wilkins D. E., Hallet M., Wess M. M. Audiogenic startle reflex of man and its relationship to startle syndromes. Brain. 109:1986;561-573.
58. Zigmond M. J., Stricker E. M. Deficits in feeding behavior after intraventricular injection of 6-hydroxydopamine in rats. Science. 177:1972;1211-1214.