The application of capillary electrophoresis for monitoring effects of excipients on protein conformation

Journal of Pharmaceutical and Biomedical Analysis

Volumn 16, Issue 6, 1998, Pages 1097-1105

  McIntosh, Kylie A ^a   Charman, William N ^a   Charman, Susan A ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Capillary electrophoresis; Excipients; Ribonuclease A; Thermal unfolding

Indexed keywords

CITRIC ACID; EXCIPIENT; HEXYLENE GLYCOL; MACROGOL 400; RIBONUCLEASE A; SORBITOL; SUCROSE;

ARTICLE; CAPILLARY ELECTROPHORESIS; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; PH; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DENATURATION; TEMPERATURE SENSITIVITY;

BUFFERS; CIRCULAR DICHROISM; ELECTROPHORESIS, CAPILLARY; EXCIPIENTS; HYDROGEN-ION CONCENTRATION; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; RIBONUCLEASE, PANCREATIC; SPECTROPHOTOMETRY, ULTRAVIOLET; TEMPERATURE;

EID: 0032005983     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(97)00096-4     Document Type: Article

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