Droperidol-ondansetron combination versus droperidol alone for postoperative control of emesis after total abdominal hysterectomy

Journal of Clinical Anesthesia

Volumn 10, Issue 1, 1998, Pages 6-12

  Riley, Theodore J ^a   McKenzie, Ray ^a,b   Tantisira, Boonrak R ^a,b   Hamilton, Dana L ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Droperidol; Emesis; Nausea and vomiting, postoperative; Ondansetron, complications

Indexed keywords

DROPERIDOL; ONDANSETRON;

ARTICLE; CLINICAL TRIAL; DRUG EFFICACY; FEMALE; HUMAN; HYSTERECTOMY; MAJOR CLINICAL STUDY; NAUSEA; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; VOMITING;

ADULT; ANTIEMETICS; DOUBLE-BLIND METHOD; DROPERIDOL; DRUG COMBINATIONS; FEMALE; HUMANS; HYSTERECTOMY; MIDDLE AGED; NAUSEA; ONDANSETRON; POSTOPERATIVE COMPLICATIONS; RISK FACTORS; VOMITING;

EID: 0032005502     PISSN: 09528180     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-8180(97)00188-8     Document Type: Article

References (21)

1. Rosenfeld BA: Postanesthesia care unit. In: Rogers WA, Tinker JH, Covino CG, Longnecker DE, (eds): Principles and Practice of Anesthesiology. St. Louis: Mosby Year Book, 1993:2381.
2. Naylor RJ, Rudd JA: Pharmacology of ondansetron. Eur J Anaesthesiol 1992;9 Suppl 6:3-10.
3. McKenzie R, Uy NT, Riley TJ, Hamilton DL: Droperidol/ondansetron combination controls nausea and vomiting after tubal banding. Anesth Analg 1996;83:1218-22.
4. Warde GB, O'Connor M, Dillane D, Blunnie WP: "Balanced" anti-emetic prophylaxis in patients undergoing gynecologic laparoscopy-single/double or triple therapy [Abstract]. Br J Anaesth 1995;74:A23.
5. McKenzie R, Tantisira B, Karambelkar D, Riley TJ, Abdelhady H: Comparison of ondansetron with ondansetron plus dexamethasone in the prevention of postoperative nausea and vomiting. Anesth Analg 1994;79:961-4.
6. Wrench IJ, Ward JE, Walder AD, Hobbs GJ: The prevention of postoperative nausea and vomiting using a combination of ondansetron and droperidol. Anaesthesia 1996;51:776-8.
7. Reimer EJ, Montgomery CJ, Bevan JC, Merrick PM, Blackstock D, Popovic V: Propofol anaesthesia reduces early postoperative emesis after paediatric strabismus surgery. Can J Anaesth 1993;40: 927-33.
8. Splinter WM, Rhine EJ, Roberts DW, et al: Ondansetron is a better prophylactic antiemetic than droperidol for tonsillectomy in children. Can J Anaesth 1995;42:848-51.
9. Alon E, Himmelseher S: Ondansetron in the treatment of postoperative vomiting: a randomized, double-blind comparison with droperidol and metoclopramide. Anesth Analg 1992;75: 561-5.
10. Paxton LD, McKay AC, Mirakhur RK: Prevention of nausea and vomiting after day case gynecological laparoscopy. A comparison of ondansetron, droperidol, metoclopramide and placebo. Anaesthesia 1995;50:403-6.
11. Kim H, Rosenberg SA, Steinburg SM, Cole DJ, Weber JS: A randomized double-blinded comparison of the antiemetic efficacy of ondansetron and droperidol in patients receiving high-dose interleukin-2. J Immunotherapy 1994;16:60-5.
12. Gan TJ, Collis R, Hetreed M: Double-blind comparison of ondansetron, droperidol and saline in the prevention of postoperative nausea and vomiting. Br J Anaesth 1994;72:544-7.
13. Fischler M, Bonnet F, Trang H, et al: The pharmacodynamics of droperidol in anesthetized patients. Anesthesiology 1986;64: 486-9.
14. McKenzie R, Kovac A, O'Connor T et al: Comparison of ondansetron versus placebo to prevent postoperative nausea and vomiting in women undergoing ambulatory gynecologic surgery. Anesthesiology 1993;78:21-8.
15. Lunn DV, Lauder GR, Williams AR, Pickering RM, McQuillan PJ: Low-dose droperidol reduces nausea and vomiting in a pediatric day surgery. Br J Anaesth 1995;74:509-11.
16. Grond S, Lynch J, Diefenbach C, Altrock K, Lehmann KA: Comparison of ondansetron and droperidol in the prevention of nausea and vomiting after inpatient minor gynecologic surgery. Anesth Analg 1995;81:603-7.
17. Melnick BM: Extrapyramidal reactions to low-dose droperidol. Anesthesiology 1988;69:424-6.
18. Desilva PH, Darvish AH, McDonald SM, Cronin MK, Clark K: The efficacy of prophylactic ondansetron, droperidol, perphenazine, and metoclopramide in the prevention of nausea and vomiting after major gynecologic surgery. Anesth Analg 1995;81:139-43.
19. Davis PJ, McGowan FX Jr, Landsman I, Maloney K, Hoffmann P: Effect of antiemetic therapy on recovery and hospital discharge time. A double-blind assessment of ondansetron, droperidol, and placebo in pediatric patients undergoing ambulatory surgery. Anesthesiology 1995;83:956-60.
20. Palazzo M, Evans R: Logistic regression analysis of fixed patient factors for postoperative sickness: a model for risk assessment. Br J Anaesth 1993;70:135-40.
21. Cohen MM, Duncan PG, DeBoer DP, Tweed WA: The postoperative interview: assessing risk factors for nausea and vomiting. Anesth Analg 1994;78:7-16.