Effects of thrombospondin-1 on disease course and angiogenesis in rat adjuvant-induced arthritis

Clinical Immunology and Immunopathology

Volumn 86, Issue 2, 1998, Pages 199-208

  Koch, Alisa E ^a,b   Szekanecz, Zoltan ^a,d   Friedman, Jon ^a   Haines, G Kenneth ^a   Langman, Craig B ^a,c   Bouck, Noel P ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b DEPARTMENT OF VETERANS AFFAIRS   (United States)

^c CHILDREN'S MEMORIAL HOSPITAL   (United States)

^d UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

POLYMACON; THROMBOSPONDIN 1;

ADJUVANT ARTHRITIS; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ADHESION; DISEASE SEVERITY; EXTRAVASATION; IMPLANT; INFLAMMATION; LEUKOCYTE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; RAT; SYNOVIUM; WEIGHT REDUCTION;

EID: 0032005453     PISSN: 00901229     EISSN: None     Source Type: Journal    
DOI: 10.1006/clin.1997.4480     Document Type: Article

References (53)

1. Haynes B. F., Hale L. P., Denning S. M., Le P. T., Singer K. H. The role of leukocyte adhesion molecules in cellular interactions: implications for the pathogenesis of inflammatory synovitis. Springer Semin. Immunopathol. 11:1989;163-185.
2. Szekanecz Z., Szegedi G., Koch A. E. Cellular adhesion molecules in rheumatoid arthritis: Regulation by cytokines and possible clinical importance. J. Investig. Med. 44:1996;124-135.
3. Koch A. E., Kunkel S. L., Strieter R. M. Cytokines in rheumatoid arthritis. J. Investig. Med. 43:1995;28-38.
4. Colville-Nash P. R., Scott D. L. Angiogenesis and rheumatoid arthritis: Pathogenic and therapeutic implications. Ann. Rheum. Dis. 51:1992;919-925.
5. Halloran M. M., Szekanecz Z., Barquin N., Haines G. K., Koch A. E. Cellular adhesion molecules in rat adjuvant arthritis. Arthritis Rheum. 39:1996;810-819.
6. Langman C. B., Ford K. K., Pachman L. M., Glorieux F. Vitamin D metabolism in rats with adjuvant-induced arthritis. J. Bone Miner. Res. 5:1990;905-913.
7. Issekutz T. B., Issekutz A. C. T lymphocyte migration to arthritic joints and dermal inflammation in the rat: Differing migration patterns and the involvement of VLA-4. Clin. Immunol. Immunopathol. 61:1991;436-447.
8. Bornstein P. Thrombospondins: Structure and regulation of expression. FASEB J. 6:1992;3290-3299.
9. DiPietro L. A., Polverini P. J. Angiogenic macrophages produce the angiogenic inhibitor thrombospondin 1. Am. J. Pathol. 143:1993;678-684.
10. Booth W. J., Berndt M. C. Thrombospondin in clinical disease states. Semin. Thromb. Hemost. 13:1987;298-306.
11. Gao A. G., Lindberg F. P., Finn M. B., Blystone S. D., Brown E. J., Frazier W. A. Integrin-associated protein is a receptor for the C-terminal domain of thrombospondin. J. Biol. Chem. 271:1996;21-24.
12. Lawler J., Hynes R. O. Structural organization of the thrombospondin molecule. Semin. Thromb. Hemost. 13:1987;245-254.
13. Huh H. Y., Lo S. K., Yesner L. M., Silverstein R. L. CD36 induction on human monocytes upon adhesion to tumor necrosis factor-activated endothelial cells. J. Biol. Chem. 270:1995;6267-6271.
14. Tuszynski G. P., Kowalska M. A. Thrombospondin-induced adhesion of human platelets. J. Clin. Invest. 87:1991;1387-1394.
15. Lawler J., Hynes R. O. An integrin receptor on normal and thrombasthenic platelets that binds thrombospondin. Blood. 74:1989;2022-2027.
16. DeFreitas M. F., Yoshida C. K., Frazier W. A., Mendrick D. L., Kypta R. M., Reichardt L. F. Identification of integrin alpha 3 beta 1 as a neuronal thrombospondin receptor mediating neurite outgrowth. Neuron. 15:1995;333-343.
17. Yabkowitz R., Dixit V. M., Guo N., Roberts D. D., Shimizu Y. Activated T-cell adhesion to thrombospondin is mediated by the alpha 4 beta 1 (VLA-4) and alpha 5 beta 1 (VLA-5) integrins. J. Immunol. 151:1993;149-158.
18. Tsao P. W., Mousa S. A. Thrombospondin mediates calcium mobilization in fibroblasts via its Arg-Gly-Asp and carboxyl-terminal domains. J. Biol. Chem. 270:1995;23747-23753.
19. Suchard S. J., Burton M. J., Dixit V. M., Boxer L. A. Human neutrophil adherence to thrombospondin occurs through a CD11/CD18-independent mechanism. J. Immunol. 146:1991;3945-3952.
20. Schuepp B. J., Jungi T. W. Thrombospondin-exposed human monocytes display augmented luminol-enhanced chemiluminescence upon receptor triggering. Biochem. Biophys. Res. Commun. 177:1991;1087-1094.
21. Mansfield P. J., Suchard S. J. Thrombospondin promotes chemotaxis and haptotaxis of human peripheral blood monocytes. J. Immunol. 153:1994;4219-4229.
22. Mansfield P. J., Boxer L. A., Suchard S. J. Thrombospondin stimulates motility of human neutrophils. J. Cell Biol. 111:1990;3077-3086.
23. Tuszynski G. P., Nicosia R. F. The role of thrombospondin-1 in tumor progression and angiogenesis. Bioessays. 18:1996;71-76.
24. Lahav J. The functions of thrombospondin and its involvement in physiology and pathophysiology. Biochim. Biophys. Acta. 1182:1993;1-14.
25. Dameron K. M., Volpert O. V., Tainsky M. A., Bouck N. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science. 265:1994;1582-1584.
26. DiPietro L. A., Nebgen D. R., Polverini P. J. Downregulation of endothelial cell thrombospondin 1 enhances in vitro angiogenesis. J. Vasc. Res. 31:1994;178-185.
27. Good D. J., Polverini P. J., Rastinejad F., Le Beau M. M., Lemons R. S., Frazier W. A., Bouck N. P. A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin. Proc. Natl. Acad. Sci. USA. 87:1990;6624-6628.
28. Rastinejad F., Polverini P. J., Bouck N. P. Regulation of the activity of a new inhibitor of angiogenesis by a cancer suppressor gene. Cell. 56:1989;345-355.
29. Tolsma S. S., Volpert O. V., Good D. J., Frazier W. A., Polverini P. J., Bouck N. Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity. J. Cell Biol. 122:1993;497-511.
30. BenEzra D., Griffin B. W., Maftzir G., Aharonov O. Thrombospondin and in vivo angiogenesis induced by basic fibroblast growth factor or lipopolysaccharide. Invest. Ophthalmol. Vis. Sci. 34:1993;3601-3608.
31. Koch A. E., Friedman J., Burrows J. C., Haines G. K., Bouck N. P. Localization of the angiogenesis inhibitor thrombospondin in human synovial tissues. Pathobiology. 61:1993;1-6.
32. Szekanecz Z., Szabo G., Sonkoly I., Bedo Z., Szegedi G. Effect of pentoxifylline on decreased in vitro mononuclear leucocyte chemotaxis in vascular and polysystemic autoimmune diseases. Agents Actions. 33:1991;254-259.
33. Dawes J., Clemetson K. J., Gogstad G. O., McGregor J., Clezardin P., Prowse C. V., Pepper D. S. A radioimmunoassay for thrombospondin, used in a comparative study of thrombospondin, beta-thromboglobulin and platelet factor 4 in healthy volunteers. Thromb. Res. 29:1983;569-581.
34. Huber A. R., Ellis S., Johnson K. J., Dixit V. M., Varani J. Monocyte diapedesis through an in vitro vessel wall construct: Inhibition with monoclonal antibodies to thrombospondin. J. Leukocyte Biol. 52:1992;524-528.
35. Suchard S. J., Boxer L. A., Dixit V. M. Activation of human neutrophils increases thrombospondin receptor expression. J. Immunol. 147:1991;651-659.
36. Johnson B. A., Haines G. K., Harlow L. A., Koch A. E. Adhesion molecule expression in human synovial tissue. Arthritis Rheum. 36:1993;137-146.
37. Barbadillo C., G-Arroyo A., Salas C., Mulero J., Sanchez-Madrid F., Andreu J. L. Anti-integrin immunotherapy in rheumatoid arthritis: Protective effect of anti-alpha 4 antibody in adjuvant arthritis. Springer Semin. Immunopathol. 16:1995;427-436.
38. Blue M. L., Conrad P., Webb D. L., Sarr T., Macaro M. Interacting monocytes and synoviocytes induce adhesion molecules by a cytokine-regulated process. Lymphokine Cytokine Res. 12:1993;213-218.
39. Bombara M. P., Webb D. L., Conrad P., Marlor C. W., Sarr T., Ranges G. E., Aune T. M., Greve J. M., Blue M. L. Cell contact between T cells and synovial fibroblasts causes induction of adhesion molecules and cytokines. J. Leukocyte Biol. 54:1993;399-406.
40. Huh H. Y., Pearce S. F., Yesner L. M., Schindler J. L., Silverstein R. L. Regulated expression of CD36 during monocyte-to-macrophage differentiation: Potential role of CD36 in foam cell formation. Blood. 87:1996;2020-2028.
41. Schultz-Cherry S., Chen H., Mosher D. F., Misenheimer T. M., Krutzsch H. C., Roberts D. D., Murphy-Ullrich J. E. Regulation of transforming growth factor-beta activation by discrete sequences of thrombospondin 1. J. Biol. Chem. 270:1995;7304-7310.
42. Szekanecz Z., Haines G. K., Harlow L. A., Shah M. R., Fong T. W., Fu R., Lin S. J., Rayan G., Koch A. E. Increased synovial expression of transforming growth factor (TGF)-beta receptor endoglin and TGF-beta 1 in rheumatoid arthritis: Possible interactions in the pathogenesis of the disease. Clin. Immunol. Immunopathol. 76:1995;187-194.
43. Wahl S. M., Allen J. B., Wong H. L., Dougherty S. F., Ellingsworth L. R. Antagonistic and agonistic effects of transforming growth factor-beta and IL-1 in rheumatoid synovium. J. Immunol. 145:1990;2514-2519.
44. Nicosia R. F., Tuszynski G. P. Matrix-bound thrombospondin promotes angiogenesis in vitro. J. Cell Biol. 124:1994;183-193.
45. Hamilton J. A., Piccoli D. S., Leizer T., Butler D. M., Croatto M., Royston A. K. Transforming growth factor beta stimulates urokinase-type plasminogen activator and DNA synthesis, but not prostaglandin E2 production, in human synovial fibroblasts. Proc. Natl. Acad. Sci. USA. 88:1991;7180-7184.
46. Yabkowitz R., Mansfield P. J., Ryan U. S., Suchard S. J. Thrombospondin mediates migration and potentiates platelet-derived growth factor-dependent migration of calf pulmonary artery smooth muscle cells. J. Cell Physiol. 157:1993;24-32.
47. Jackson C. J., Knop A., Giles I., Jenkins K., Schrieber L. VLA-2 mediates the interaction of collagen with endothelium during in vitro vascular tube formation. Cell Biol. Int. 18:1994;859-867.
48. Brooks P. C., Clark R. A., Cheresh D. A. Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science. 264:1994;569-571.
49. Peacock D. J., Banquerigo M. L., Brahn E. A novel angiogenesis inhibitor suppresses rat adjuvant arthritis. Cell. Immunol. 160:1995;178-184.
50. Weinstat-Saslow D. L., Zabrenetzky V. S., VanHoutte K., Frazier W. A., Roberts D. D., Steeg P. S. Transfection of thrombospondin-1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential and angiogenesis. Cancer Res. 54:1994;6504-6511.
51. Brooks P. C., Montgomery A. M., Rosenfeld M., Reisfeld R. A., Hu T., Klier G., Cheresh D. A. Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell. 79:1994;1157-1164.
52. Moses M. A. A cartilage-derived inhibitor of neovascularization and metalloproteinases. Clin. Exp. Rheumatol. 8:1993;S67-S69.
53. Wahl S. M., Allen J. B., Hines K. L., Imamichi T., Wahl A. M., Furcht L. T., McCarthy J. B. Synthetic fibronectin peptides suppress arthritis in rats by interrupting leukocyte adhesion and recruitment. J. Clin. Invest. 94:1994;655-662.