Activation of outward current by pituitary adenylate cyclase activating polypeptide in mouse microglial cells

Journal of Neuroscience Research

Volumn 51, Issue 3, 1998, Pages 382-390

  Ichinose, Mitsuyuki ^a   Asai, Masatoshi ^a   Sawada, Masashi ^a  

^a SHIMANE UNIVERSITY   (Japan)

Author keywords

Neuropeptide; Patch clamp; Potassium current

Indexed keywords

4 AMINOPYRIDINE; CHARYBDOTOXIN; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE RECEPTOR; ION CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; QUININE; RECEPTOR BLOCKING AGENT; TETRYLAMMONIUM;

ANIMAL CELL; ARTICLE; DOSE RESPONSE; IMMUNOMODULATION; MEMBRANE ELECTROPHYSIOLOGY; MICROGLIA; MOUSE; NEUROIMMUNOLOGY; NEUROTRANSMISSION; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL;

ANIMALS; CELLS, CULTURED; LINEAR MODELS; MEMBRANE POTENTIALS; MICE; MICE, INBRED BALB C; MICROGLIA; NEUROPEPTIDES; PATCH-CLAMP TECHNIQUES; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; POTASSIUM CHANNEL BLOCKERS; RECEPTORS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RECEPTORS, PITUITARY HORMONE;

EID: 0032005304     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19980201)51:3<382::AID-JNR11>3.0.CO;2-9     Document Type: Article

References (33)

1. Chedeville A, Mirossay L, Chastre E, Hurbain-Kosmath I, Lopez M, Gespach C (1993): Interaction of VIP, PACAP and related peptides in normal and leukemic human monocytes and macrophages. FEBS Lett 319:171-176.
2. Christophe J (1993): Type I receptors for PACAP (a neuropeptide even more important than VIP?) Biochim Biophys Acta 1154:183-199.
3. Davis EJ, Foster TD, Thomas WE (1994): Cellular forms and functions of brain microglia. Brain Res Bull 34:73-78.
4. De la Fuente M, Del Rio M, Ferrandez MD, Hernanz A (1991): Modulation of phagocytic function in murine peritoneal macrophages by bombesin, gastrin-releasing peptide and neuromedin C. Immunology 73:205-211.
5. Delgado M, De la Fuente M, Martinez C, Gomariz RP (1995): Pituitary adenylate cyclase-activating polypeptides (PACAP27 and PACAP38) inhibit the mobility of murine thymocytes and splenic lymphocytes: Comparison with VIP and implication of cAMP. J Neuroimmunol 62:137-146.
6. Delgado M, Garrido E, De la Fuente M, Gomariz RP (1996a): Pituitary adenylate cyclase-activating polypeptide (PACAP-38) stimulates rat peritoneal macrophage functions. Peptides 17:1097-1105.
7. + thymocytes from glucocorticoid-induced apoptosis. Blood 87:5152-5161.
8. Garrido E, Delgado M, Martinez C, Gomariz RP, De la Fuente M (1996): Pituitary adenylate cyclase-activating polypeptide (PACAP38) modulates lymphocyte and macrophage functions; stimulation of adherence and opposite effect on mobility. Neuropeptides 30:583-595.
9. Gaytan F, Martinez-Fuentes AJ, Garcia-Navarro F, Vaudry H, Aguilar E (1994): Pituitary adenylate cyclase-activating peptide (PACAP) immunolocalization in lymphoid tissues of the rat. Cell Tissue Res 276:223-227.
10. Gehrmann J, Matsumoto Y, Kreutzberg GW (1995): Microglia: Intrinsic immuneffector cell of the brain. Brain Res Rev 20:269-287.
11. 2+ influx in mouse macrophages. Comp Biochem Physiol 97A:417-421.
12. + conductance by adrenaline in mouse peritoneal macrophages. Pflugers Arch 419:371-379.
13. Harmar T, Lutz E (1994): Multiple receptors for PACAP and VIP Trends Pharmacol Sci 15:97-99.
14. Ichinose M, Hara N, Sawada M, Maeno T (1992): The neuropeptide, neuromedin C, activates a potassium current in mouse macrophages. FEBS Lett 314:458-460.
15. Ichinose M, Asai M, Imai K, Sawada M (1995): Enhancement of phagocytosis in mouse macrophages by pituitary adenylate cyclase activating polypeptide (PACAP) and related peptides. Immunopharmacology 30:217-224.
16. Ilschner S, Nolte C, Kettenmann H (1996): Complement factor C5a and epidermal growth factor trigger the activation of outward potassium currents in cultured murine microglia. Neuroscience 73:1109-1120.
17. Kreutzberg GW (1996): Microglia: A sensor for pathological events in the CNS. Trends Neurosci 19:312-318.
18. Martin DL (1992): Synthesis and release of neuroactive substances by glial cells. Glia 5:81-94.
19. Miyata A, Arimura A, Dahl RR, Minamino N, Uehara A, Jiang L, Culler MD, Coy DH (1989): Isolation of a novel 38 residuehypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells. Biochem Biophys Res Commun 164:567-574.
20. Miyata A, Jiang L, Dahl RD, Kitada C, Kubo K, Fujimoto M, Minamino N, Arimura A (1990): Isolation of a neuropeptide corresponding to the N-terminal 27 residues of the pituitary adenylate cyclase activating polypeptides with 38 residues (PACAP38). Biochem Biophys Res Commun 170:643-648.
21. Moller K, Zhang Y-Z, Hakanson R, Luts A, Sjolund B, Uddman R, Sundler F (1993): Pituitary adenylate cyclase activating peptide is a sensory neuropeptide: Immunocytochemical and immunochemical evidence. Neuroscience 57:725-732.
22. Nakajima K, Kohsaka S (1993): Functional roles of microglia in the brain. Neurosci Res 17:187-203.
23. Ogi K, Miyamoto Y, Masuda Y, Habata Y, Hosoya M, Ohtaki T, Masuo Y, Onda H, Fujino M (1993): Molecular cloning and functional expression of a cDNA encording a human pituitary adenylate cyclase activating polypeptide receptor. Biochem Biophys Res Commun 196:1511-1521.
24. Robberecht P, Gourlet P, De Neef P, Woussen-Colle M-C, Vandermeers-Piret M-C, Vandermeers A, Christophe J (1992): Structural requirements for the occupancy of pituitary adenylate-cyclase-activating-peptide (PACAP) receptors and adenylate cyclase activation in human neuroblastoma NB-OK-1 cell membranes; Discovery of PACAP(6-38) as a potent antagonist. Eur J Biochem 207:239-246.
25. - channels and their involvement in proliferation of rat microglial cells. Glia 17:225-236.
26. Savino W, Dardenne M (1996): Immune-neuroendocrine interactions. Immunol Today 16:318-322.
27. Streit WJ (1993): Microglial-neuronal interactions. J Chem Neuroanat 6:261-266.
28. Suzumura A, Mezitis SGE, Gonatas NK, Silberberg DH (1987): MHC antigen expression on bulk isolated macrophage-microglia from newborn mouse brain: Induction of Ia antigen expression by γ-interferon. J Neuroimmunol 15:263-278.
29. Tatsuno I, Gottschall PE, Arimura A (1991a): Specific binding sites for pituitary adenylate cyclase activating polypeptide (PACAP) in rat cultured astrocytes: Molecular identification and interaction with vasoactive intestinal peptide (VIP). Peptides 12:617-621.
30. Tatsuno I, Gottschall PE, Arimura A (1991b): Inhibition of mitogenstimulated proliferation of murine splenocytes by a novel neuropeptide, pituitary adenylate cyclase activating polypeptide: A comparative study with vasoactive intestinal peptide. Endocrinol 128:728-734.
31. Unanue ER, Allen PM (1987): The basis for the immunoregulatory role of macrophages and other accessory cells. Science 236:551-557.
32. + conductance in cultures microglial cells from mouse brain. J Neurosci 13:4403-1411.
33. Warren JB, Larkin SW, Coughlan M, Kajekar R, Williams TJ (1992): Pituitary adenylate cyclase activating polypeptide is a potent vasodilator and oedema potentiator in rabbit skin in vitro. Br J Pharmacol 106:331-334.