Alteration in Immune Responsiveness during the Peripartum Period and Its Ramification on Dairy Cow and Calf Health

Journal of Dairy Science

Volumn 81, Issue 2, 1998, Pages 585-595

  Mallard, B A ^a   Dekkers, J C ^a   Ireland, M J ^a   Leslie, K E ^a   Sharif, S ^a   Vankampen, C Lacey ^a   Wagter, L ^a   Wilkie, B N ^a  

^a UNIVERSITY OF GUELPH   (Canada)

Author keywords

Health; Immune response; Mastitis; Periparturient period

Indexed keywords

ANIMAL; ANIMAL DISEASE; CATTLE; CATTLE DISEASE; FEMALE; GENETICS; HEALTH STATUS; IMMUNOLOGY; INFECTION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBPOPULATION; NEWBORN; PREGNANCY; REVIEW;

ANIMALS; ANIMALS, NEWBORN; CATTLE; CATTLE DISEASES; FEMALE; HEALTH STATUS; INFECTION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBSETS; PREGNANCY;

EID: 0031991538     PISSN: 00220302     EISSN: None     Source Type: Journal    
DOI: 10.3168/jds.S0022-0302(98)75612-7     Document Type: Conference Paper

References (88)

1. Barendse, W., S. M. Armitage, L. M. Kossarek, A. Shalom, B. W. Kirkpatrick, A. M. Ryan, D. Clayton, L. Li, H. L. Neibergs, N. Zhang, W. M. Grosse, J. Weiss, P. Creighton, F. McCarthy, M. Ron, A. J. Teale, R. Rries, R. A. McGraw, S. S. Moore, M. Georges, M. Soller, J. E. Womack, and D.J.S. Hetzel. 1994. A genetic linkage map of the bovine genome. Nat. Genet. 6:227-235.
2. Bath, D. L., F. N. Dickinson, H. A. Tucker, and R. D. Appleman. 1985. Pages 298-299 in Dairy Cattle: Principles, Practices, Problems, Profits. 3rd ed. Lea & Febiger, Philadelphia, PA.
3. Beer, A. E., R. E. Billingham, and J. Head. 1974. The immunological significance of the mammary gland. J. Invest. Dermatol. 63:65-74.
4. Bourry, A., and B. Poutrel. 1997. Bovine mastitis caused by Listeria monocytogenes: kinetics of antibody responses in serum and milk after experimental infection. J. Dairy Sci. 79: 2189-2195.
5. Burton, J. L., E. B. Burnside, B. W. Kennedy, B. N. Wilkie, and J. H. Burton. 1989. Antibody responses to human erythrocytes and ovalbumin as marker traits of disease resistance in dairy calves. J. Dairy Sci. 72:1252-1265.
6. Burton, J. L., and M. E. Kehrli. 1996. Effects of dexamethasone on bovine circulating T lymphocyte populations. J. Leukocyte Biol. 59:90-99.
7. Burton, J. L., B. A. Mallard, and D. N. Mowat. 1993. Effects of supplemental chromium on immune responses of periparturient and early lactation dairy cows. J. Anim. Sci. 71:1532-1539.
8. Burton, J. L., R. W. McBride, B. W. Kennedy, J. H. Burton, T. H. Elsasser, and B. Woodward. 1991. Serum immunoglobulin profiles of dairy cows chronically treated with recombinant bovine somatotropin. J. Dairy Sci. 74:1589-1598.
9. Burton, J. L., B. W. McBride, B. W. Kennedy, J. H. Burton, T. H. Elsasser, and B. Woodward. 1991. Influence of exogenous bovine somatotropin on the responsiveness of peripheral blood lymphocytes to mitogen. J. Dairy Sci. 74:916-928.
10. Burton, J. L., B. W. McBride, B. W. Kennedy, J. H. Burton, T. H. Elsasser, and B. Woodward. 1992. Contact sensitivity and systemic antibody responses in dairy cows treated with recombinant bovine somatotropin. J. Dairy Sci. 75:747-755.
11. Cai, T., P. G. Weston, L. A. Lund, B. Brodie, D. J. McKenna, and W. C. Wagner. 1994. Association between neutrophil functions and periparturient disorders in cows. Am. J. Vet. Res. 55: 934-943.
12. Caldenhoven, E., J. Liden, S. Wissink, A. Van de Stolpe, and J. Raaijmakers. 1995. Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the anti-inflammatory action of glucocorticoids. Mol. Endocrinol. 9: 401-112.
13. Chang, X., B. A. Mallard, and D. N. Mowat. 1996. Effects of chromium on health status, blood neutrophil phagocytosis and in vitro lymphocyte blastogenesis of dairy cows. Vet. Immunol. Immunopathol. 52:37-52.
14. Compton, R. 1996. Timing is everything: respiratory vaccination. Large Anim. Vet. (Jan/Feb. issue):28.
15. Concha, C. 1986. Cell types and their immunological function in bovine mammary tissues and secretions - a review of the literature. Nord. Vet. Med. 38:257-272.
16. Corbeil, L. B., B. Watt, R. R. Corbeil, T. G. Betzen, R. K. Brownson, and J. L. Morril. 1984. Immunoglobulin concentrations in serum and nasal secretions of calves at the on set of pneumonia. Am. J. Vet. Res. 45:773-778.
17. Cronstein, B. N., S. C. Kimmel, R. I. Levin, F. Martiniuk, and G. Weissman. 1992. A mechanism for the anti-inflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule I and intercellular adhesion molecule I. Proc. Natl. Acad. Sci. USA 89:9991-9995.
18. Detilleux, J. C., M. E. Kehrli, A. E. Freeman, L. K. Fox, and D. H. Kelley. 1995. Mastitis of periparturient Holstein cattle: a phenotypic and genetic study. J. Dairy Sci. 78:2285-2293.
19. Detilleux, J. C., M. E. Kehrli, J. R. Stabel, A. E. Freeman, and D. H. Kelley. 1995. Study of immunological dysfunction in periparturient Holstein cattle selected for high and average milk production. Vet. Immunol. Immunopathol. 44:251-267.
20. Detilleux, J. C., K. J. Koehler, A. E. Freeman, M. E. Kehrli, and D. H. Kelley. 1994. Immunological parameters of periparturient Holstein cattle: genetic variation. J. Dairy Sci. 77:2640-2650.
21. Eppard, P. J., J. J. Veenhuizen, W. J. Cole, P. G. Comens-Keller, G. F. Hartnell, R. L. Hintz, L. Munyakazi, P. K. Olsson, R. H. Sorbet, T. C. White, C. A. Baile, R. J. Collier, J. P. Goff, and R. L. Horst. 1996. Effects of bovine somatotropin administered to periparturient dairy cows on the incidence of metabolic disease. J. Dairy Sci. 79:2170-2181.
22. Fitzpatrick, J. L., P. J. Cripps, A. W. Hill, P. W. Bland, and C. R. Stokes. 1992. MHC class II expression in the bovine mammary gland. Vet. Immunol. Immunopathol. 32:13-23.
23. Gavora, J. S., and J. L. Spencer. 1983. Breeding for immune responsiveness and disease resistance. Anim. Blood Groups Biochem. Genet. 14:159-180.
24. Gilbert, R. O., Y. T. Grohn, P. M. Miller, and D. J. Hoffman. 1993. The effect of parity on peripartum neutrophil function in dairy cows. Vet. Immunol. Immunopathol. 36:75-82.
25. Glass, E. J., R. A. Oliver, and R. L. Spooner. 1990. Variation in T cell responses to ovalbumin in cattle: evidence for Ir gene control. Anim. Genet. 21:15-28.
26. Griffin, J.F.T. 1989. Stress and immunity: a unifying concept. Vet. Immunol. Immunopathol. 20:263-312.
27. Guidry, A. J., M. J. Paape, and R. E. Pearson. 1976. Effects of parturition and lactation on blood and milk cell concentrations, corticosteroids, and neutrophil phagocytosis in the cow. Am. J. Vet. Res. 37:1195-1200.
28. Harp, J. A., and B. J. Nonnecke. 1986. Regulation of mitogenic responses by bovine milk lymphocytes. Vet. Immunol. Immunopathol. 11:215-224.
29. Head, J. R., and A. E. Beer. 1979. Pages 207-226 in Immunology of Breast Milk: In Vivo and In Vitro Assessment of the Immunological Role of Leukocyte Cells in Milk. P. L. Ogra and D. Dayton, ed. Raven Press, New York, NY.
30. Head, J. R., and L. L. Seelig. 1983. Autoradiographic analysis of lymphocyte migration into the mammary epithelium and milk of lactating female rats. J. Reprod. Immunol. 5:61-72.
31. Heyneman, R., C. Burvensich, and R. Vercauteren. 1990. Interaction between the respiratory burst activity of neutrophil leukocytes and experimentally induced Escherichia coli mastitis in cows. J. Dairy Sci. 73:985-994.
32. Hill, A. W. 1981. Factors influencing the outcome of Escherichia coli mastitis in the dairy cow. Res. Vet. Sci. 31:107-112.
33. Hurley, D. J., M. H. Kensinger, A. M. Mastro, and R. A. Wilson. 1990. An evaluation of the mononuclear cells derived from bovine mammary gland dry secretions using leukocyte antigen specific monoclonal antibodies, light scattering properties and non-specific esterase staining. Vet. Immunol. Immunopathol. 25:177-193.
34. Ireland, M. J., C. Lacey, B. McBride, and B. A. Mallard. 1995. Insulin-like growth factor-I and growth hormone: possible immunomodulatory effects on CD markers in the periparturient Holstein. Page 323 in Proc. 4th Int. Vet. Symp. Univ. California, Davis, CA. L. Gershwin, J. Lunney, and C. Schore, ed. (Abstr.)
35. Ishikawa, H. 1987. Observation of lymphocyte function in perinatal cows and neonatal calves. Jpn. J. Vet. Sci. 49: 469-475.
36. Kashiwazaki, Y., Y. Maede, and S. Namioka. 1985. Transformation of bovine peripheral blood lymphocytes in the perinatal period. Jpn. J. Vet. Sci. 47:337-339.
37. Kehrli, M. E., B. J. Nonnecke, and J. A. Roth. 1989. Alterations in bovine peripheral blood neutrophil function during the peripartum period. Am. J. Vet. Res. 50:207-214.
38. Kehrli, M. E., B. J. Nonnecke, and J. A. Roth. 1989. Alterations in bovine peripheral blood lymphocyte function during the peripartum period. Am. J. Vet. Res. 50:215-220.
39. Kehrli, M. E., K. A. Weigel, A. E. Freeman, J. R. Thurston, and D. H. Kelley. 1991. Bovine sire effects on daughters' in vitro blood neutrophil functions, lymphocyte blastogenesis, serum complement and conglutinin levels. Vet. Immunol. Immunopathol. 27:303-319.
40. Kelley, K. W. 1989. Commentary: growth hormone, lymphocytes and macrophages. Biochem. Pharmacol. 38:705-713.
41. Kelso, A. 1995. T-helper 1 and T-helper 2: paradigm lost? Immunol. Today 16:374-379.
42. Kremer, W.D.J., E. N. Noordhuizen-Stassen, and J.A.C.M. Lohuis. 1990. Host defence and bovine coliform mastitis. Vet. Q. 12:104-113.
43. Lacey-VanKampen, C., and B. A. Mallard. 1998. Effects of peripartum stress and disease on bovine lymphocyte subsets. Vet. Immunol. Immunopathol. 59(1,2):79-92.
44. Legates, J. E., and C. D. Grinnells. 1952. Genetic relationships in resistance to mastitis in dairy cattle. J. Dairy Sci. 35: 829-833.
45. Lewin, H. A. 1989. Disease resistance and immune response genes in cattle: strategies for their detection and evidence of their existence. J. Dairy Sci. 72:1334-1348.
46. Lie, O., H. Solbu, H. J. Larsen, and R. L. Spooner. 1986. Possible association of antibody responses to human serum albumin and (T,G)-A - L with the bovine major histocompatibility complex (BoLA). Vet. Immunol. Immunopathol. 11: 333-350.
47. Lunden, A., S. Sigurdardottir, I. Edfors-Lilja, B. Danell, J. Rendel, and L. Andersson. 1990. The relationship between bovine major histocompatibility complex class II polymorphisms and disease studied by use of bull breeding values. Anim. Genet. 21:221-232.
48. Lush, J. L. 1950. Inheritance of susceptibility to mastitis. J. Dairy Sci. 33:121-125.
49. Mallard, B. A., E. B. Burnside, J. H. Burton, and B. N. Wilkie. 1982. Variation in serum immunoglobulins in Canadian Holstein-Friesians. J. Dairy Sci. 66:862-866.
50. Mallard, B. A., K. E. Leslie, J.C.M. Dekkers, R. Hedge, M. Bauman, and M. J. Stear. 1995. Differences in bovine lymphocyte antigen associations between immune responses and risk of disease following intramammary infection with Staphylacoccus aureus. J. Dairy Sci. 78:1937-1944.
51. Mallard, B. A., L. C. Wagter, M. J. Ireland, and J.C.M. Dekkers. 1997. Effects of growth hormone, insulin-like growth factor I, and cortisol on periparturient antibody response profiles of dairy cattle. Vet. Immunol. Immunopathol. 60(1-2):61-76.
52. Mazencara, K., B. W. Kennedy, E. B. Burnside, B. N. Wilkie, and J. H. Burton. 1985. Genetic parameters of bovine serum immunoglobulins. J. Dairy Sci. 68:2309-2314.
53. Mejdell, C. M., O. Lie, H. Solbu, E. F. Arnet, and R. L. Spooner. 1994. Association of major histocompatibility complex antigens with AI bull progeny test results for mastitis, ketosis and fertility in Norwegian cattle. Anim. Genet. 25:99-104.
54. Nagahata, H., S. Makino, S. Takeda, H. Takahashi, and H. Noda. 1988. Assessment of neutrophil function in the dairy cow during the perinatal period. J. Vet. Med. B 35:747-751.
55. Nagahata, H., H. Noda, and T. Abe. 1987. Changes in blastogenic response of bovine lymphocytes during acute clinical mastitis. Jpn. J. Vet. Sci. 49:1148-1150.
56. Newbould, F.H.S. 1976. Phagocytic activity of bovine leukocytes during pregnancy. Can. J. Comp. Med. 40:111-116.
57. Nickerson, S. C., W. E. Owens, J. J. Rejman, and S. P. Oliver. 1993. Effects of interleukin-1 and interleukin-2 on mammary gland leukocyte populations and histology during the early nonlactating period. Zentralbl. Veterinaermed. Reihe B. 40: 621-633.
58. Oda, S., H. Satoh, T. Matsunga, T. Kuhara, Y. Shoji, A. Nihei, M. Ohta, and Y. Sasaki. 1989. Insulin-like growth factor-I, GH, insulin, and glucagon concentrations in bovine colostrum and in plasma of dairy cows and neonatal calves around parturition. Comp. Biochem. Physiol. 94:805-812.
59. Park, Y. H., L. K. Fox, M. J. Hamilton, and W. C. Davies. 1992. Bovine mononuclear leukocyte subpopulation in peripheral blood and mammary gland secretions during lactation. J. Dairy Sci. 75:998-1006.
60. Park, Y. H., L. K. Fox, M. J. Hamilton, and W. C. Davies. 1993. Suppression of proliferative response of BoCD4+ lymphocytes by activated BoCD8+ T lymphocytes in the mammary gland of cows with Staphylococcus aureus mastitis. Vet. Immunol. Immunopathol. 36:137-151.
61. Park, Y. H., S. C. Jung, J. S. Moon, B. G. Ku, C. R. Wyatt, M. J. Hamilton, L. K. Fox, and W. C. Davies. 1994. A subset of mammary gland gamma-delta T lymphocytes downregulates BoCD4 T lymphocytes response to Staphylococcus aureus in cattle with intramammary infection. Korean J. Immunol. 16: 19-27.
62. Parmley, M. J., A. E. Beer, and R. E. Billingham. 1976. In vitro studies on the T-lymphocyte population of human milk. J. Exp. Med. 144:358-370.
63. Peter, A. T., and W.T.K. Bosu. 1987. Peripartal endocrine changes associated with retained placenta in dairy cows. Theriogenology 28:383-393.
64. Quiroga, G. H., S. C. Nickerson, and R. W. Atkinson. 1993. Histological response of the heifer mammary gland to intramammary infusion of interleukin-2 or interferon-γ. J. Dairy Sci. 76:2913-2924.
65. Reidel-Caspari, G. 1993. The influence of colostral leukocytes on the course of an experimental Escherichia coli infection and serum antibodies in neonatal calves. Vet. Immunol. Immunopathol. 35:275-288.
66. Reidel-Caspari, G., and F. W. Schmidt. 1991. The influence of colostral leukocytes on the immune system of the neonatal calf. I. Effects on lymphocyte responses. Dtsch. Tieraerztl. Wochenschr. 98:102-107.
67. Reidel-Caspari, G., and F. W. Schmidt. 1991. The influence of colostral leukocytes on the immune system of the neonatal calf. II. Effects on phagocytosis. Dtsch. Tieraerztl. Wochenschr. 98: 330-334.
68. Rewinski, M. J., and T. J. Yang. 1994. Lactation stage-dependent changes in levels of tumour necrosis factor/cachectin in milk. Am. J. Reprod. Immunol. 31:170-176.
69. Richie, E. R., R. Bass, M. L. Meistrich, and D. K. Dennison. 1982. Distribution of T lymphocyte subsets in human colostrum. J. Immunol. 129:1116-1119.
70. Saad, A. M., C. Concha, and G. Åstrom. 1989. Alterations in neutrophil phagocytosis and lymphocyte blastogenesis in dairy cows around parturition. J. Vet. Med. 36:337-345.
71. Schukken, Y. H., B. A. Mallard, J.C.M. Dekkers, K. E. Leslie, and M. J. Stear. 1994. Genetic impact on the risk of intramammary infection following Staphylococcus aureus challenge. J. Dairy Sci. 77:639-647.
72. Shafer-Weaver, K. A., G. M. Pighetti, and L. M. Sordillo. 1996. Diminished mammary gland lymphocyte functions parallel shifts in trafficking patterns during the postpartum period. Proc. Soc. Exp. Biol. Med. 212:271-279.
73. Sidney, J., H. M. Grey, R. T. Kubo, and A. Sette. 1996. Practical biochemical and evolutionary implications of the discovery of HLA class I supermotifs. Immunol. Today 17:261-266.
74. Solbu, H. 1984. Disease recording in Norwegian dairy cattle. II. Heritability estimates and progeny testing for mastitis, ketosis, and "all diseases". Z. Tierz. Zuechtungsbiol. 101:51-58.
75. Sordillo, L. M., G. Afseth, G. Davies, and L. A. Babiuk. 1992. Effects of recombinant granulocyte-macrophage colony-stimulating factor on bovine peripheral blood and mammary gland neutrophil function in vitro. J. Vet. Res. 56:16-21.
76. Sordillo, L. M., M. J. Redmen, M. Campos, L. Warren, and L. A. Babiuk. 1991. Cytokine activity in bovine mammary gland secretions during the periparturient period. Can. J. Vet. Res. 55:298-301.
77. Taylor, B. C., J. D. Dellinger, J. S. Cullor, and J. L. Scott. 1994. Bovine milk lymphocytes display the phenotype of memory T-cells and are predominantly CD8+. Cell. Immunol. 156:245-253.
78. Torre, P. M., P. K. Konur, and S. P. Oliver. 1992. Proliferative response of mammary gland mononuclear cells to recombinant bovine interleukin-2. Vet. Immunol. Immunopathol. 32: 351-358.
79. Tuboly, S., S. Bernath, R. Glavits, and I. Medveczky. 1988. Intestinal absorption of colostral lymphoid cells in newborn piglets. Vet. Immunol. Immunopathol. 20:75-85.
80. Vega, J. R., A. Gibson, T. C. Skaar, D. L. Hadsell, and C. R. Baumruker. 1991. Insulin-like growth factor I and II and IGF binding proteins in serum and mammary secretions during the dry period and early lactation in dairy cows. J. Anim. Sci. 69: 2538-2547.
81. Wagter, L. C., B. A. Mallard, J.C.M. Dekkers, K. E. Leslie, and B. N. Wilkie. 1996. Characterization of immune responsiveness and disease occurrence during the peripartum period. J. Dairy Sci. 79(Suppl. 1):119.(Abstr.)
82. Watson, D. L. 1980. Immunological functions of the mammary gland and its secretion - comparative review. Aust. J. Biol. Sci. 33:403-422.
83. Watson, D. L., and H. I. Davies. 1985. Immunophysiological activity of supramammary lymph nodes of the ewe during early phase of staphylococcal mastitis. Res. Vet. Sci. 39:52-58.
84. Weigel, K. A., M. E. Kehrli, A. E. Freeman, J. R. Thurston, M. J. Stear, and D. H. Kelley. 1991. Associations of class I bovine lymphocyte antigen complex alleles with in vitro blood neutrophil functions, lymphocyte blastogenesis, serum complement, and conglutinin levels in airy cattle. Vet. Immunol. Immunopathol. 27:321-335.
85. Westermann, J., and R. Pabst. 1996. How organ-specific is the migration of naive and memory T-cells? Immunol. Today 17: 278-282.
86. Williams, P. P. 1993. Immunomodulating effects of intestinal absorbed maternal colostral leukocytes by neonatal pigs. Can. J. Vet. Res. 57:1-8.
87. Yang, T. J., J. F. Mather, and E. D. Rabinovsky. 1988. Changes in subpopulation of lymphocytes in peripheral blood, and supramammary and prescapular lymph nodes in cows with mastitis and normal cows. Vet. Immunol. Immunopathol. 18: 279-285.
88. Zecconi, A., V. Bronzo, R. Piecinini, G. Spreafico, and G. Ruffo. 1994. Phagocytic activity of bovine polymorphonuclear neutrophil leucocytes. J. Dairy Res. 61:271-279.