메뉴 건너뛰기




Volumn 25, Issue 1, 1998, Pages 47-52

In vivo properties of N-(2-aminoethyl)-5-halogeno-2-pyridinecarboxamide 18F- and 123I-labelled reversible inhibitors of monoamine oxidase B

Author keywords

123I labelling; 18F labelling; Inhibitor; MAO B; Metabolite

Indexed keywords

FLUORINE 18; IODINE 123; LAZABEMIDE; MONOAMINE OXIDASE B INHIBITOR; PICOLINIC ACID DERIVATIVE;

EID: 0031986267     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(97)00143-1     Document Type: Article
Times cited : (16)

References (22)
  • 1
    • 0027142562 scopus 로고
    • New analogs of N-(2-amino-ethyl)-4-chlorobenzamide (Ro 16-6491): Some of the most potent monoamine oxidase-B inactivators
    • 1. Annan N. and Silverman R. B. (1993) New analogs of N-(2-amino-ethyl)-4-chlorobenzamide (Ro 16-6491): Some of the most potent monoamine oxidase-B inactivators. J. Med. Chem. 36, 3968-3970.
    • (1993) J. Med. Chem. , vol.36 , pp. 3968-3970
    • Annan, N.1    Silverman, R.B.2
  • 7
    • 0026520063 scopus 로고
    • The new generation of monoamine oxidase inhibitors
    • 7. Cesura A. M. and Pletscher A. (1992) The new generation of monoamine oxidase inhibitors. Progr. Drug Res. 38, 171-297.
    • (1992) Progr. Drug Res. , vol.38 , pp. 171-297
    • Cesura, A.M.1    Pletscher, A.2
  • 8
    • 0028353855 scopus 로고
    • Characterization of the enzyme responsible for the metabolism of sumatriptan in human liver
    • 8. Dixon C. M., Park G. R. and Tarbit M. H. (1994) Characterization of the enzyme responsible for the metabolism of sumatriptan in human liver. Biochem. Pharmacol. 47, 1253-1257.
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 1253-1257
    • Dixon, C.M.1    Park, G.R.2    Tarbit, M.H.3
  • 10
    • 0001786846 scopus 로고
    • Cytochrome P-450 enzymes and drug metabolism
    • 10. Guengerich F. P. (1987) Cytochrome P-450 enzymes and drug metabolism. Prog. Drug Metab. 10, 1-54.
    • (1987) Prog. Drug Metab. , vol.10 , pp. 1-54
    • Guengerich, F.P.1
  • 11
    • 0010989066 scopus 로고
    • Functionalized linear tetra-aza ligands for complexing technetium: Potential species for antibody labelling
    • 11. Huber G. J., Alberto R. A., Bläuenstein P. and Anderegg G. (1989) Functionalized linear tetra-aza ligands for complexing technetium: Potential species for antibody labelling. J. Chem. Soc. Chem. Commun., 879-881.
    • (1989) J. Chem. Soc. Chem. Commun. , pp. 879-881
    • Huber, G.J.1    Alberto, R.A.2    Bläuenstein, P.3    Anderegg, G.4
  • 12
    • 0025656309 scopus 로고
    • Visualization of brain monoamino oxidase B (MAO-B) in dementia of Alzheimer's type by means of large cryosection autoradiography: A pilot study
    • 12. Jossan S. S., Gillberg P.-G., Karlsson I., Gottfries C. G. and Oreland L. (1990) Visualization of brain monoamino oxidase B (MAO-B) in dementia of Alzheimer's type by means of large cryosection autoradiography: A pilot study. J. Neural Transm. 32, 61-65.
    • (1990) J. Neural Transm. , vol.32 , pp. 61-65
    • Jossan, S.S.1    Gillberg, P.-G.2    Karlsson, I.3    Gottfries, C.G.4    Oreland, L.5
  • 13
    • 0028915184 scopus 로고
    • The prediction of the lipophilicity of peptidomimetics: A comparison between experimental and theoretical lipophilicity values of renin inhibitors and their building blocks
    • 13. Karajiannis H. and van de Waterbeemd H. (1995) The prediction of the lipophilicity of peptidomimetics: A comparison between experimental and theoretical lipophilicity values of renin inhibitors and their building blocks. Pharm. Acta Helv. 70, 67-77.
    • (1995) Pharm. Acta Helv. , vol.70 , pp. 67-77
    • Karajiannis, H.1    Van De Waterbeemd, H.2
  • 14
    • 0028894476 scopus 로고
    • Platelet and brain GABA-transaminase and monoamine oxidase activities in patients with complex partial seizures
    • 14. Kumlien E., Sherif F., Ge L. and Oreland L. (1995) Platelet and brain GABA-transaminase and monoamine oxidase activities in patients with complex partial seizures. Epilepsy Res. 20, 161-170.
    • (1995) Epilepsy Res. , vol.20 , pp. 161-170
    • Kumlien, E.1    Sherif, F.2    Ge, L.3    Oreland, L.4
  • 15
    • 0027198126 scopus 로고
    • Symptomatic anti-Parkinson effects of monoamine oxidase-B inhibition: Comparison of selegiline and lazabemide
    • 15. LeWitt P. A., Segel S. A., Mistura K. L. and Schork M. A. (1993) Symptomatic anti-Parkinson effects of monoamine oxidase-B inhibition: Comparison of selegiline and lazabemide. Clin. Neuropharm. 16, 332-337.
    • (1993) Clin. Neuropharm. , vol.16 , pp. 332-337
    • LeWitt, P.A.1    Segel, S.A.2    Mistura, K.L.3    Schork, M.A.4
  • 17
    • 0011028392 scopus 로고
    • Darstellung einiger 4-und 5-substituierter Pyridin-2-carbonsäuren als Fusarsäureanaloga
    • 17. Oehlke J., Schrötter E., Dove S., Schick H. and Niedrich H. (1983) Darstellung einiger 4-und 5-substituierter Pyridin-2-carbonsäuren als Fusarsäureanaloga. Pharmazie 38, 591-596.
    • (1983) Pharmazie , vol.38 , pp. 591-596
    • Oehlke, J.1    Schrötter, E.2    Dove, S.3    Schick, H.4    Niedrich, H.5
  • 18
    • 0028332856 scopus 로고
    • Aromatic and amine substituent effects on the apparent lipophilicities of N-[(2-pyrolidinyl)methyl]-substituted benzamides
    • 18. Schmidt D. E., Votaw J. R., Kessler R. M. and de Paulis T. (1994) Aromatic and amine substituent effects on the apparent lipophilicities of N-[(2-pyrolidinyl)methyl]-substituted benzamides. J. Pharmacol. Sci. 83, 305-315.
    • (1994) J. Pharmacol. Sci. , vol.83 , pp. 305-315
    • Schmidt, D.E.1    Votaw, J.R.2    Kessler, R.M.3    De Paulis, T.4
  • 20
    • 0024452316 scopus 로고
    • Xenobiotic oxidation catalysed by aldehyde dehydrogenases
    • 20. Sladek N. E., Manthey C. L., Maki P. A. and Zhang Z. (1989) Xenobiotic oxidation catalysed by aldehyde dehydrogenases. Drug Metab. Rev. 20, 697-720.
    • (1989) Drug Metab. Rev. , vol.20 , pp. 697-720
    • Sladek, N.E.1    Manthey, C.L.2    Maki, P.A.3    Zhang, Z.4
  • 21
    • 0025259341 scopus 로고
    • Determination of the monoamine oxidase B inhibitor Ro 19-6327 in plasma by high-performance liquid chromatography using precolumn derivatisation with fluorescamine and fluorescence detection
    • 21. Wyss R. and Philipp W. (1990) Determination of the monoamine oxidase B inhibitor Ro 19-6327 in plasma by high-performance liquid chromatography using precolumn derivatisation with fluorescamine and fluorescence detection. J. Chromatogr. 507, 187-198.
    • (1990) J. Chromatogr. , vol.507 , pp. 187-198
    • Wyss, R.1    Philipp, W.2
  • 22
    • 0025622915 scopus 로고
    • The role of monoamino oxidase, iron-melanin interaction, and intracellular calcium in Parkinson's disease
    • 22. Youdim M. B. H., Ben-Shachar D. and Riederer P. (1990) The role of monoamino oxidase, iron-melanin interaction, and intracellular calcium in Parkinson's disease. J. Neural Transm. 32, 239-248.
    • (1990) J. Neural Transm. , vol.32 , pp. 239-248
    • Youdim, M.B.H.1    Ben-Shachar, D.2    Riederer, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.