Endometrial leukocytes are altered numerically and functionally in women with implantation defects

American Journal of Reproductive Immunology

Volumn 39, Issue 1, 1998, Pages 1-11

  Stewart Akers, Ann M ^a   Krasnow, Joel S ^a   Brekosky, Jill ^a   DeLoia, Julie A ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Endometrial leukocytes; T cells; Th1 cytokines; Th2 cytokines

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; AUTOIMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOMETRIUM; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LEUKOCYTE COUNT; LEUKOCYTE FUNCTION; NIDATION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUBFERTILITY; T LYMPHOCYTE; THYROID DISEASE;

EID: 0031986083     PISSN: 87558920     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0897.1998.tb00326.x     Document Type: Article

References (42)

1. Kearns M. Lala PK: Bone marrow origin of decidual cell precursor in the pseudopregnant mouse uters J Exp Med 1982: 155:1537-1554.
2. King A, Welling V, Gardner L, Loke YW: Immunocytochemi- cal characterization of the unusual large granular lymphocytes in human endometrium throughout the menstrual cycle. Hum Immunol 1989; 24:195-205.
3. Bulmer JN, Morrison L, Longfellow M, Ritson A, Pace D: Granulated lymphocytes in human endometrium: Histochemical and immunohistochemical studies. Hum Reprod 1991; 6:791-798.
4. Klentzeris LD, Bulmer JN, Warren A, Morrison L, Lit TC, Cooke ID: Endometrial lymphoid tissue in the timed endometrial biopsy: Morphometric and immunohistrochemical aspects. Am J Obstet Gynecol 1992; 167:667-674.
5. δ T cells and adhesion molecules in endometriotic tissue in petients with endometriosis and adenomyosis. Am J Reprod Immunol 1996; 35:477-482.
6. Klentzeris LD, Bulmer JN, Warren MA, Morrison L, Li TC, Cooke ID: Lymphoid tissue in the endometrium of women with unexplained infertility: Morphometric and immunohistochemical aspects. Hum Reprod 1994; 9:646-652.
7. King A, Loke YW: On the nature and function of human utering granular lymphocytes. Immunol Today 1991; 12:432-435.
8. Pollard JW, Hunt JS, Wiktor-Jedrzejczak W, Stanley ER: A pregnancy defect in the osteopetrotic (op/op) mouse demonstrates the requirement for CSF-1 in female fertility. Dev Biol 1991; 148:273-283.
9. Guimond MJ, Luross JA, Wang B, Terhorst C, Danial S, Croy BA: Absence of natural killer cells during murine pregnancy is associated with reproductive compromise in TgE26 mice. Biol Reprod 1997; 56:169-179.
10. Robertson SA, Seamark RF, Guilbert LJ, Wegmann TG: The role of cytokines in gestation. Crit Rev Immunol 1994; 14:239-292.
11. Lin H, Mosmann TR, Guilbert L, Tuntipopipat S, Wegmann TG: Synthesis of T helper 2-type cytokines at the maternalfetal interface. J Immunol 1993; 151:4562-4573.
12. Wegmann TG, Lin H, Guilbert L, Mosmann TR: Bidirectional cytokine interactions in the maternal-fetal relationship: Is successful pregnancy a Th2 phenomenon? Immunol Today 1993; 14:353-356.
13. Krasnow JS, Tollerude D, Naus G, DeLoia JA: T-helper 2 cytokine expression in the endometrium throughout the menstrual cycle and early pregnancy. Hum Reprod 1996; 11:1747-1754.
14. Ferry BL, Sargent IL, Starkey PM, Redman CWG: Cytotoxic activity against trophoblast and choriocarcinoma cells of large granular lymphocytes from human early pregnancy decidua. Cell Immunol 1991; 132:140-149.
15. Tangri S, Raghupathy R: Expression of cytokines in placentas of mice undergoing immunologically mediated spontaneous fetal resorptions. Biol Reprod 1993; 49:850-856.
16. Geva E, Amit A, Lerner-Geva L, Azem F, Yovel I, Lessing JB: Autoimmune disorders: Another possible casue for invitro fertilization and embryo transfer failure. Hum Reprod 1995; 10:2560-2563.
17. Singh A, Dantas ZN, Stone SC, Asch RH: Presence of thyroid antibodies in early reproductive failure: Biochemical versus clinical pregnancies. Fertil Steril 1995; 63:277-281.
18. Wu Z, Podack ER, McKenzie JM, Olsen KJ, Zakrija M: Perforin expression by thyroid-infiltrating T cells in autoimmune thyroid disease. Clin Exp Immunol 1994; 98:470-477.
19. Marazuela M, Vargas JA, Durantez A, Alvarez-Mon M: T lymphocyte activation in Graves' disease. Endocr Res 1994; 20:291-306.
20. Gessl A, Wilfing A, AGis H, Steiner G, Czernin S, BoltzNitulescu G, Vierhapper H, Waldhausl W: Activated naïve CD4+ peripheral blood T cells in autoimmune thyroid disease. Thyroid 1995; 5:117-123.
21. Tas M, Haan-Meulman MD, Kabel PJ, Drexhage HA: Defects in monocyte polarization and dendritic cell clustering in patients with Graves' disease. A putative role for a nonspecific immunoregulatory factor related to retroviral p15E. Clin Endocrinol 1991; 34:441-448.
22. Noyes RW, Hertig AT, Rock J: Dating the endometrial biopsy. Fertil Steril 1950; 1:3-25.
23. Chirgwin JM, Arnheim AE, MacDonald RJ, Rutter W: Isolation of biologically active ribonucleic acid sources enriched in ribonuclease. Biochemistry 1979; 18:5294-5299.
24. Derynck R, Jarrett JA, Chen EY, Goeddel DV: The murine transforming growth factor-β precursor. J Biol Chem 1986; 261:4377-4379.
25. Stewart CJR, Farquharson MA, Foulis AK: The distribution and possible function of gamma interferon-immunoreactive cells in normal endometrium and myometrium. Virchows Arch A Pathol Anat Histopathol 1992; 420:419-424.
26. Skoskiewicz MJ, Colvin RB, Schneeberger EE, Russell PS: Widespread and selective induction of major histocompatibility complex-derived antigens in vivo by γ interferon. J Exp Med 1985; 162:1645-1664.
27. Basham T, Smith W, Lanier L, Morhenn V, Merigan T: Regulation of expression of class II major histocompatibiliy antigens on human peripheral blood monocytes and Langerhans cells by interferon. Hum Immunol 1984; 10:83-93.
28. deWaal-Malefyt R, Abrams J, Bennett B, Figdor C, Vries JE: Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes. J Exp Med 1991; 174:1209-1220.
29. Chaouat G, Meliani AA, Martal J, Raghupathy R, Elliot J, Mosmann T, Wegmann TG: IL-10 prevents naturally occurring fetal loss in the CBA × DBA/2 mating combination, and local defect in IL-10 production in this abortion-prone combination is corrected by in vivo injection of IFN-tau. J Immunol 1995; 154:4261-4268.
30. Tezabwala BU, Johnson PM, Rees RC: Inhibition of pregnancy viability in mice following IL-2 administration. Immunology 1989; 67:115-119.
31. Chaouat G, Menu E, Clark DA, Dy M, Minkowski M, Wegmann TG: Control of fetal survival in CBA × DBA/2 mice by lymphokine therapy. J Reprod Fertil 1990; 89:447-458.
32. bright natural killer cells in the human early pregnancy decidua. Int Immunol 1993; 5:599-563.
33. Jokhi PP, King A, Sharkey AM, Smith SK, Loke YW: Screening for cytokin messenger ribonucleic acids in purified human decidual lymphocyte populations by the reverse-transcriptase polymerase chain reaction. J Immunol 1994; 153:4427-4434.
34. Espevik T, Figari IS, Shalaby MR, Lackides GA, Lewis GD, Shepard HM, Palladino MA: Inhibition of cytokine production by cyclosporin A and transforming growth factor β. J Exp Med 1987; 166:571-576.
35. Peleman R, Wu J, Fargeas C, Delespesse G: Recombinant interleukin 4 suppresses the production of interferin γ by human mononuclear cells. J Exp Med 1989; 170:1751-1756.
36. Billiau A: Interferon-γ biology and role in pathogenesis. Adv Immunol 1996; 62:61-130.
37. Fiorentino DF, Bond MW, Mosmann TR: Two types of mouse T helper cells. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med 1989; 170:2081-2095.
38. Chomarat P, Rissoan MC, Banchereau J, Miossec P: Interferon γ inhibits interleukin 10 production by monocytes. J Exp Med 1993; 177:523-527.
39. Enk AH, Katz SI: Identification and induction of keratinocyte-derived IL-10. J Immunol 1992; 149:92-95.
40. 125I]TGFβ1-binding sites. Endocrinology 1994; 135:439-449.
41. Zhang L, Rees MCP, Bicknell R: The isolation and longterm culture of normal human endometrial epithelium and stroma. Expression of mRNAs for angiogenic polypeptides basally and on oestrogen and progesterone challenges. J Cell Sci 1995; 108:323-331.
42. Tabibzadeh SS, Bettica A, Gerber MA: Variable expression of Ia antigens in human endometrium and in chronic endometritis. Am J Clin Pathol 1986; 86:153-160.