메뉴 건너뛰기




Volumn 77, Issue 4, 1998, Pages 581-587

Suppression by pravastatin, an inhibitor of p21(ras) isoprenylation, of hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats

Author keywords

Hepatocarcinogenesis; N nitrosomorpholine; P21(ras) isoprenylation; Pravastatin

Indexed keywords

GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE TRANSFERASE; MEMBRANE PROTEIN; NITROSOMORPHOLINE; PRAVASTATIN; PROTEIN P21; RAS PROTEIN;

EID: 0031985149     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1998.94     Document Type: Article
Times cited : (30)

References (34)
  • 1
    • 0030860560 scopus 로고    scopus 로고
    • Analysis of Ha-ras gene mutation of hepatic lesions induced by N-nitrosomorpholine and inhibition of hepatocarcinogenesis in Sprague-Dawley rats by mutated Ha-ras antisense
    • Baba M, Yamamoto R, Iishi H and Tatsuta M (1997) Analysis of Ha-ras gene mutation of hepatic lesions induced by N-nitrosomorpholine and inhibition of hepatocarcinogenesis in Sprague-Dawley rats by mutated Ha-ras antisense. Int J Cancer 72: 815-820
    • (1997) Int J Cancer , vol.72 , pp. 815-820
    • Baba, M.1    Yamamoto, R.2    Iishi, H.3    Tatsuta, M.4
  • 2
    • 0026607503 scopus 로고
    • Cholesterol inhibition, cancer and chemotherapy
    • Buchwald H (1992) Cholesterol inhibition, cancer and chemotherapy. Lancet 339: 1154-1156
    • (1992) Lancet , vol.339 , pp. 1154-1156
    • Buchwald, H.1
  • 3
    • 0027026591 scopus 로고
    • Protein prenylation: More than just glue?
    • Cox AD and Der CJ (1992) Protein prenylation: more than just glue? Curr Opin Cell Biol 4: 1008-1016
    • (1992) Curr Opin Cell Biol , vol.4 , pp. 1008-1016
    • Cox, A.D.1    Der, C.J.2
  • 6
    • 0027422247 scopus 로고
    • The pathway to signal achievement
    • Egan SE and Weinberg RA (1993) The pathway to signal achievement. Nature 365: 781-783
    • (1993) Nature , vol.365 , pp. 781-783
    • Egan, S.E.1    Weinberg, R.A.2
  • 7
    • 0021281136 scopus 로고
    • Relationship between mevalonate and mitogenesis in human fibroblasts stimulated with platelet-derived growth factor
    • Fairbanks KP, Witte LD and Goodman DS (1981) Relationship between mevalonate and mitogenesis in human fibroblasts stimulated with platelet-derived growth factor. J Biol Chem 259: 1546-1551
    • (1981) J Biol Chem , vol.259 , pp. 1546-1551
    • Fairbanks, K.P.1    Witte, L.D.2    Goodman, D.S.3
  • 8
    • 0018746012 scopus 로고
    • Inhibition of cholesterol synthesis with compactin renders growth of cultured cell dependent on the low density lipoprotein receptors
    • Goldstein JL, Helgeson JAS and Brown MS (1979) Inhibition of cholesterol synthesis with compactin renders growth of cultured cell dependent on the low density lipoprotein receptors. J Biol Chem 254: 5403-5409
    • (1979) J Biol Chem , vol.254 , pp. 5403-5409
    • Goldstein, J.L.1    Helgeson, J.A.S.2    Brown, M.S.3
  • 9
    • 0026079628 scopus 로고
    • The biochemistry of ras p21
    • Grand RJA and Owen D (1991) The biochemistry of ras p21. Biochem J 279: 609-631
    • (1991) Biochem J , vol.279 , pp. 609-631
    • Grand, R.J.A.1    Owen, D.2
  • 10
    • 0019903249 scopus 로고
    • Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication
    • Gratzner HG (1982) Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: a new reagent for detection of DNA replication. Science 218: 474-475
    • (1982) Science , vol.218 , pp. 474-475
    • Gratzner, H.G.1
  • 11
    • 0022500482 scopus 로고
    • Oncogenes in human primary hepatic cancer
    • Gu JR, Hu LF, Cheng YC and Wan DF (1986) Oncogenes in human primary hepatic cancer. J Cell Physiol 4 (Suppl): 13-20
    • (1986) J Cell Physiol , vol.4 , Issue.SUPPL. , pp. 13-20
    • Gu, J.R.1    Hu, L.F.2    Cheng, Y.C.3    Wan, D.F.4
  • 12
    • 0019305204 scopus 로고
    • Relation of cholesterol and mevalonic acid to the cell cycle in smooth muscle and Swiss 3T3 cells stimulated to divide by platelet-derived growth factor
    • Habenicht AJR, Glomset JA and Ross R (1980) Relation of cholesterol and mevalonic acid to the cell cycle in smooth muscle and Swiss 3T3 cells stimulated to divide by platelet-derived growth factor. J Biol Chem 255: 5134-5140
    • (1980) J Biol Chem , vol.255 , pp. 5134-5140
    • Habenicht, A.J.R.1    Glomset, J.A.2    Ross, R.3
  • 13
    • 0028944922 scopus 로고
    • Influence of cholesterol supply on cell growth and differentiation in cultured enterocytes (CoCa-2)
    • Herold G, Jungwirth R, Rogler G, Geerling I and Stange EF (1995) Influence of cholesterol supply on cell growth and differentiation in cultured enterocytes (CoCa-2). Digestion 56: 57-66
    • (1995) Digestion , vol.56 , pp. 57-66
    • Herold, G.1    Jungwirth, R.2    Rogler, G.3    Geerling, I.4    Stange, E.F.5
  • 14
    • 0018853824 scopus 로고
    • Histologic typing of liver tumors of the rats
    • Institute of Laboratory Animal Resources (1980) Histologic typing of liver tumors of the rats. J Natl Cancer Inst 64: 177-207
    • (1980) J Natl Cancer Inst , vol.64 , pp. 177-207
  • 15
    • 0027081322 scopus 로고
    • Effect of pravastatin, a potent 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, on survival of AH 130 hepatoma-bearing rats
    • Kawata S, Kakimoto H, Ishiguro H, Yamasaki E, Inui Y and Matsuzawa Y (1992) Effect of pravastatin, a potent 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, on survival of AH 130 hepatoma-bearing rats. Jpn J Cancer Res 83: 1120-1123
    • (1992) Jpn J Cancer Res , vol.83 , pp. 1120-1123
    • Kawata, S.1    Kakimoto, H.2    Ishiguro, H.3    Yamasaki, E.4    Inui, Y.5    Matsuzawa, Y.6
  • 16
    • 0028300763 scopus 로고
    • Modulation of the mevalonate pathway and cell growth by pravastatin and d-limonene in a human hepatoma cell line (Hep G2)
    • Kawata S, Nagase T, Yamasaki E, Ishiguro H and Matsuzawa Y (1994) Modulation of the mevalonate pathway and cell growth by pravastatin and d-limonene in a human hepatoma cell line (Hep G2). Br J Cancer 69: 1015-1020
    • (1994) Br J Cancer , vol.69 , pp. 1015-1020
    • Kawata, S.1    Nagase, T.2    Yamasaki, E.3    Ishiguro, H.4    Matsuzawa, Y.5
  • 18
    • 0021362772 scopus 로고
    • Induction of differentiation in murine neuroblastoma cells by mevinolin, a competitive inhibitor of 3-hydroxyl-3-methylglutaryl coenzyme A reductase
    • Maltese WA (1984) Induction of differentiation in murine neuroblastoma cells by mevinolin, a competitive inhibitor of 3-hydroxyl-3-methylglutaryl coenzyme A reductase. Biochem Biophys Res Commun 120: 454-460
    • (1984) Biochem Biophys Res Commun , vol.120 , pp. 454-460
    • Maltese, W.A.1
  • 19
    • 0022413876 scopus 로고
    • Suppression of murine neuroblastoma growth in vivo by mevinolin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase
    • Maltese WA, Defendini R, Green RA, Sheridan KM and Donley DK (1985) Suppression of murine neuroblastoma growth in vivo by mevinolin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase. J Clin Invest 76: 1748-1754
    • (1985) J Clin Invest , vol.76 , pp. 1748-1754
    • Maltese, W.A.1    Defendini, R.2    Green, R.A.3    Sheridan, K.M.4    Donley, D.K.5
  • 20
    • 0027212082 scopus 로고
    • How receptors turn RAS on
    • McCormick F (1993) How receptors turn RAS on. Nature 363: 15-16
    • (1993) Nature , vol.363 , pp. 15-16
    • McCormick, F.1
  • 22
    • 0029302315 scopus 로고
    • Effect of lovastatin alone and as an adjuvant chemotherapeutic agent on hepatoma tissue culture-4 cell growth
    • Morris TJ, Palm SL, Furcht LL and Buchwald H (1995) Effect of lovastatin alone and as an adjuvant chemotherapeutic agent on hepatoma tissue culture-4 cell growth. Ann Surg Oncol 2: 266-274
    • (1995) Ann Surg Oncol , vol.2 , pp. 266-274
    • Morris, T.J.1    Palm, S.L.2    Furcht, L.L.3    Buchwald, H.4
  • 24
    • 0027978838 scopus 로고
    • Prevention of 1,2-dimethylhydrazine-induced colon tumorigenesis by HMG-CoA reductase inhibitors, pravastatin and simvastatin, in ICR mice
    • Narisawa T, Fukaura Y, Terada K, Umezawa A, Tanida N, Yazawa K and Ishikawa C (1994) Prevention of 1,2-dimethylhydrazine-induced colon tumorigenesis by HMG-CoA reductase inhibitors, pravastatin and simvastatin, in ICR mice. Carcinogenesis 15: 2045-2048
    • (1994) Carcinogenesis , vol.15 , pp. 2045-2048
    • Narisawa, T.1    Fukaura, Y.2    Terada, K.3    Umezawa, A.4    Tanida, N.5    Yazawa, K.6    Ishikawa, C.7
  • 25
    • 77957179539 scopus 로고
    • Carcinogenicity and mutagenicity studies with fluvastatin, a new, entirely synthetic HMG-CoA reductase inhibitor
    • Robinson RL, Suter W and Cox RH (1994) Carcinogenicity and mutagenicity studies with fluvastatin, a new, entirely synthetic HMG-CoA reductase inhibitor. Fundam Appl Toxicol 23: 9-20
    • (1994) Fundam Appl Toxicol , vol.23 , pp. 9-20
    • Robinson, R.L.1    Suter, W.2    Cox, R.H.3
  • 27
    • 0026059558 scopus 로고
    • Nonradioactive labeling of oligonucleotides in vitro with the hapten digoxigenin by tailing with terminal transferase
    • Schmitz GG, Walter T, Seibl R and Kessler C (1991) Nonradioactive labeling of oligonucleotides in vitro with the hapten digoxigenin by tailing with terminal transferase. Anal Biochem 192: 222-231
    • (1991) Anal Biochem , vol.192 , pp. 222-231
    • Schmitz, G.G.1    Walter, T.2    Seibl, R.3    Kessler, C.4
  • 29
    • 0025202968 scopus 로고
    • Differential inhibitory effects of lovastatin on protein isoprenylation and sterol synthesis
    • Sinensky M, Back LA, Leonard S and Evans R (1990) Differential inhibitory effects of lovastatin on protein isoprenylation and sterol synthesis. J Biol Chem 265: 19937-19941
    • (1990) J Biol Chem , vol.265 , pp. 19937-19941
    • Sinensky, M.1    Back, L.A.2    Leonard, S.3    Evans, R.4
  • 31
    • 0014787893 scopus 로고
    • The unlabeled antibody enzyme method of immunochemistry. Preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochaetes
    • Sternberg LA, Hardy PH, Cuculis JJ and Mayer HG (1970) The unlabeled antibody enzyme method of immunochemistry. Preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochaetes. J Histochem Cytochem 8: 315-333
    • (1970) J Histochem Cytochem , vol.8 , pp. 315-333
    • Sternberg, L.A.1    Hardy, P.H.2    Cuculis, J.J.3    Mayer, H.G.4
  • 34
    • 0028358194 scopus 로고
    • Cytotoxicity of simvastatin to pancreatic adenocarcinoma cells containing mutant ras gene
    • Ura H, Obara T, Nishino N, Tanno S, Okamura K and Namiki M (1994) Cytotoxicity of simvastatin to pancreatic adenocarcinoma cells containing mutant ras gene. Jpn J Cancer Res 85: 633-638
    • (1994) Jpn J Cancer Res , vol.85 , pp. 633-638
    • Ura, H.1    Obara, T.2    Nishino, N.3    Tanno, S.4    Okamura, K.5    Namiki, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.