Multinucleated epithelial giant cell changes in esophagitis: A clinicopathologic study of 14 cases

American Journal of Surgical Pathology

Volumn 22, Issue 1, 1998, Pages 93-99

  Singh, Surendra P ^a   Odze, Robert D ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Dysplasia; Esophagitis; Giant cells; Herpes infection; Multinucleated cells

Indexed keywords

ALENDRONIC ACID; CYTOKERATIN;

ABDOMINAL PAIN; ADULT; AGED; ARTICLE; CANDIDIASIS; CLINICAL ARTICLE; CLINICAL EXAMINATION; DYSPHAGIA; ESOPHAGITIS; ESOPHAGOSCOPY; ESOPHAGUS BIOPSY; FEMALE; GASTROESOPHAGEAL REFLUX; GASTROINTESTINAL HEMORRHAGE; GIANT CELL; HEARTBURN; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MULTINUCLEAR CELL; RADIATION INJURY;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, NUCLEAR; CYTOMEGALOVIRUS; DNA, VIRAL; EPITHELIAL CELLS; ESOPHAGITIS; ESOPHAGOSCOPY; ESOPHAGUS; FEMALE; GIANT CELLS; HERPESVIRUS 1, HUMAN; HERPESVIRUS 2, HUMAN; HUMANS; IMMUNOENZYME TECHNIQUES; IN SITU HYBRIDIZATION; KI-67 ANTIGEN; MALE; MIDDLE AGED; NUCLEAR PROTEINS; PAPILLOMAVIRIDAE;

EID: 0031984836     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-199801000-00012     Document Type: Article

References (21)

1. Al-Saleh W, Delvenne P, Greimers R, Fridman V, Doyen J, Bon- iver J. Assessment of Ki-67 antigen immunostaining in squamous intraepithelial lesions of the uterine cervix. Correlation with the histologic grade and human papillomavirus type. Am J Clin Pathol 1995;104:154-60.
2. Berthrong M, Fajardo LF. Radiation injury in surgical pathology. Part II. Alimentary tract. Am J Surg Pathol 1981;5:153-78.
3. Carr NJ, Bratthauer GL, Lichy JH, Taubenberger JK, Monihan JM, Sobin LH. Squamous cell papillomas of the esophagus. A study of 23 lesions for human papillomavirus by in situ hybridization and the polymerase chain reaction. Hum Pathol 1994;25:536-40.
4. Castell DO. Pill esophagitis - the case of alendronate. N Engl J Med 1996;335:1058-9.
5. Goldman H, Antonioli DA. Mucosal biopsy of the esophagus, stomach, and proximal duodenum. Hum Pathol 1982;13:423-48.
6. Greenson JK, Beschorner WE, Boitontt JK, Yardley JH. Prominent mononuelear cell infiltrate is characteristic of herpes esophagitis. Hum Pathol 1991;22:541-9.
7. Groen PC, Lubbe DF, Hirch LJ, et al. Esophagitis associated with the use of atendronate. N Engl J Med 1996;335:1016-21.
8. Hinnant KL, Rotterdam HZ, Bell ET, Tapper ML. Cytomegalovirus infection of the alimentary tract: a clinicopathological correlation. Am J Gastroenterol 1986;81:944-50.
9. Hsu SM, Raine L, Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 1981;29:577-80.
10. Kimura S, Hatano H. Multinucleated cells epidermal cells in nonneoplastic dermatoses. Br J Dermatol 1978;99:485-9.
11. Manard AM, Marnay J, Gignoyx M, et al. Cancer of the esophagus and associated lesions: detailed pathologic study of 100 esophagoectomy specimens. Hum Pathol 1984;15:660-9.
12. McDougall JK, Myerson D, Beckemann AM. Detection of viral DNA and RNA by in situ hybridization. J Histochem Cytoehem 1986;34:33-8.
13. McLachlin CM, Mutter GL, Crum CP. Multinucleated atypia of the vulva. Report of a distinct entity not associated with human papillomavirus. Am J Surg Pathol 1994;18:1233-9.
14. Nash G, Ross JS. Herpetic esophagitis. A common cause of esophageal ulceration. Hum Pathol 1974;5:339-45.
15. Odze R, Antonioli D, Shocket D, Noble-Topham S, Goldman H, Upton M. Esophageal squamous papillomas. A clinicopathologic study of 38 lesions and analysis for human papillomavirus by the polymerase chain reaction. Am J Surg Pathol 1993;17:803-12.
16. Ofuji S, Horio T. Epidermal multinucleated giant cell in parapsoriasis guttata and eczematous dermatitis. Acta Derm Venereol 1970;50:252-4.
17. Omar A, Wiesmann UN, Krebs A. Induction of multinucleate cells by 8-MOP and UV treatment in vitro and in vivo. Dermatologica 1977;155:65-77.
18. Spechler SJ. Barrett's esophagus. Semin Oncol 1994;21:431-7.
19. Tagami H, Uehara M. Multinucleated epidermal giant cells in inflammatory skin diseases. Arch Dermatol 1981;117:23-5.
20. Theise ND, Rotterdam H, Dieterich D. Cytomegalovirus esophagitis in AIDS: diagnosis by endoscopic biopsy. Am J Gastroenterol 1991;86:1123-6.
21. Wenig BM, Thompson LDR, Frankel SS, et al. Lymphoid changes of the nasopharyngeal and palatine tonsils that are indicative of human immunodeficiency virus infection: a clinicopathologic study of 12 cases. Am J Surg Pathol 1996;20:572-87.