Neurobehavioral effects of anandamide and cannabinoid receptor gene expression in mice

Brain Research Bulletin

Volumn 45, Issue 1, 1998, Pages 67-74

  Chakrabarti, Amitabha ^b   Ekuta, Jethro E ^c   Onaivi, Emmanuel S ^a,b,d  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MEHARRY MEDICAL COLLEGE   (United States)

^d Neurobehavioral Research Institute   (United States)

Author keywords

Anandamides; Anxiety; Ataxia; Cannabinoids; Catalepsy; Gene expression; Mouse strains

Indexed keywords

ANANDAMIDE; CANNABINOID RECEPTOR; DRONABINOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATAXIA; BEHAVIOR; CATALEPSY; CONTROLLED STUDY; DOSE RESPONSE; EMOTIONALITY; GENE EXPRESSION REGULATION; LOCOMOTION; MALE; MOTOR PERFORMANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEREOTYPY;

ANIMALS; ARACHIDONIC ACIDS; ATAXIA; BRAIN; CANNABINOIDS; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, INBRED ICR; MOTOR ACTIVITY; POLYUNSATURATED ALKAMIDES; RECEPTORS, CANNABINOID; RECEPTORS, DRUG; SPECIES SPECIFICITY; STEREOTYPED BEHAVIOR;

EID: 0031984785     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(97)00291-8     Document Type: Article

References (26)

1. Aceto M. D., Martin B. R., Scates S. M., Lowe J. Cannabinoid precipitated withdrawal Induction by the antagonist SR 141716A . FASEB J. 9:1995;2320.
2. Barlow C., Hirotsune S., Paylor R., Liyanage M., Eckhaus M., Collins F., Shiloh Y., Crawley J. N., Reid T., Tagle D., Wynshaw-Boris A. Atm-deficient mice A paradigm of ataxia telangiectasia . Cell. 86:1996;159-171.
3. Bramblett R. D., Panu A. M., Ballesteros J. A., Reggio P. H. Construction of a 3D model of the cannabinoids CB1 receptor Determination of the helix ends and helix orientation . Life Sci. 56:1995;1971-1982.
4. 9-tetrahydrocannabinol (THC). Biochem. Pharmacol. 49:1995;855-858.
5. Chakrabarti A., Onaivi E. S., Chaudhuri G. Cloning and sequencing of a cDNA encoding the mouse brain-type cannabinoid receptor protein. DNA Sequence. 5:1995;385-388.
6. Chomczynski P., Sacchi N. Single-step method of RNA isolation by guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
7. Devane W. A., Hanus L., Breuer A., Pertwee R. G., Stevenson L. A., Griffin G., Gibson D., Mandelbaum A., Etinger A., Mechoulam R. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science. 258:1992;1946-1949.
8. Fride E., Mechoulam R. Pharmacological activity of the cannabinoid agonist, anandamide, a brain constituent. Eur. J. Pharmacol. 231:1993;313-314.
9. Gerard C. M., Mollereau C., Vassart G., Parmentier M. Molecular cloning of a human cannabinoid receptor which is also expressed in the testis. Biochem. J. 279:1991;129-134.
10. Hanus L., Gopher A., Almog S., Mechoulam R. Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor. J. Med. Chem. 36:1993;3032-3034.
11. Hoehe M. R., Caenazzo L., Martinez M. M., Hsieh W.-T., Modi W. S., Gershon E. S., Bonner T. I. Genetic and physical mapping of the human cannabinoid receptor gene to chromosome 6q14-q15. New Biol. 3:1991;880-885.
12. Martin B. R., Compton D. R., Thomas B. F., Prescott W. R., Little P. J., Razdan R. K., Johnson M. R., Melvin L. S., Mecholam R., Ward S. J. Behavioral, biochemical, and molecular modelling evaluations of cannabinoid analogs. Pharmacol. Biochem. Behav. 40:1991;471-478.
13. Martin B. R., Balster R. L., Razdan R. K., Harris L. S., Dewey W. L. Behavioral comparisons of the stereoisomers of tetrahydrocannabinols. Life Sci. 29:1981;565-574.
14. Matsuda L. A., Lolait S. J., Brownstein M. J., Young A. C., Bonner T. I. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature. 346:1990;561-564.
15. Munro S., Thomas K. L., Abu-Shaar M. Molecular characterization of a peripheral receptor for cannabinoids. Nature. 365:1993;61-65.
16. Onaivi E. S., Bishop-Robinson C., Darmani N. A., Sanders-Bush E. Behavioral effects of (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane, (DOI) in the elevated-plus-maze. Life Sci. 57:1995;2455-2466.
17. 9-THC and cannabinoid receptor gene expression in mice. Behav. Brain Res. 72:1995;115-125.
18. Onaivi E. S., Green M. R., Martin B. R. Pharmacological characterization of cannabinoids in the elevated plus-maze. J. Pharmacol. Ther. 253:1990;1002-1009.
19. Onaivi E. S., Chakrabarti A., Chaudhuri G. Cannabinoid receptor genes. Prog. Neurobiol. 48:1996;275-305.
20. Pertwee R. G. The ring test A quantitative method for assessing the cataleptic effect of cannabis in mice . Br. J. Pharmacol. 46:1972;753-763.
21. Rinaldi-Carmona M., Barth F., Heaulme M., Shire D., Calandra B., Congy C., Martinez S., Maruani J., Neliat G., Caput D., Ferrara P., Soubrie P., Breliere J. C., Le Fur G. SR 141716A, a potent and selective antagonist of the brain cannabinoid receptor. FEBS Lett. 350:1994;240-244.
22. Rushton R., Steinberg H. Mutual potentiation of amphetamine and amylobarbitone measured by activity in rats. Br. J. Pharmacol. 21:1963;295-305.
23. Salonen M., Onaivi E. S., Maze M. Dexmedetomidine synergism with midazolam in the elevated plus-maze tests in rats. Psychopharmacology (Berlin). 108:1992;229-234.
24. Smith P. B., Compton D. R., Welch S. P., Razdan R. K., Mechoulam R., Martin B. R. The pharmacological activity of anandamide, a putative endogenous cannabinoid, in mice. J. Pharmacol. Exp. Ther. 256:1994;219-227.
25. Stubbs L., Chittenden L., Chakrabarti A., Onaivi E. S. The mouse cannabinoid receptor gene is located in proximal chromosome 4. Mammal. Genome. 7:1996;165-166.
26. Vogel Z., Barg J., Levy R., Saya D., Heldman E., Mechoulam R. Anandamide, a brain endogenous compound, interacts specifically with cannabinoid receptors and inhibits adenylate cyclase. J. Neurochem. 61:1993;352-355.