-
1
-
-
0021249468
-
Effects of a new antiarrhythmic compound SUN 1165 [N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride] on the sodium currents in isolated single rat ventricular cells
-
Yatani A, Akaike N. Effects of a new antiarrhythmic compound SUN 1165 [N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride] on the sodium currents in isolated single rat ventricular cells. Naunyn Schmiedebergs Arch Pharmacol 1984;326:163-8.
-
(1984)
Naunyn Schmiedebergs Arch Pharmacol
, vol.326
, pp. 163-168
-
-
Yatani, A.1
Akaike, N.2
-
2
-
-
0021815705
-
New antiarrhythmic agents: N-aryl-8-pyrrolizidinealkanamides
-
Miyano S, Sumoto K, Satoh F, et al. New antiarrhythmic agents: N-aryl-8-pyrrolizidinealkanamides. J Med Chem 1985;28:714-7.
-
(1985)
J Med Chem
, vol.28
, pp. 714-717
-
-
Miyano, S.1
Sumoto, K.2
Satoh, F.3
-
3
-
-
0022406609
-
N-(2,6-Dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate (SUN 1165): A new potent and long-acting antiarrhythmic agent
-
Aisaka K, Hidaka T, Inomata N, Hamasaki S, Ishihara T, Morita M. N-(2,6-Dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate (SUN 1165): a new potent and long-acting antiarrhythmic agent. Arzneimittelforsch/Drug Res 1985;35:1239-45.
-
(1985)
Arzneimittelforsch/Drug Res
, vol.35
, pp. 1239-1245
-
-
Aisaka, K.1
Hidaka, T.2
Inomata, N.3
Hamasaki, S.4
Ishihara, T.5
Morita, M.6
-
4
-
-
0021855145
-
Canine digitalis arrhythmia as a model for detecting Na-channel blocking antiarrhythmic drugs: A comparative study using other canine arrhythmia models and the new antiarrhythmic drugs, propafenone, tocainide, and SUN 1165
-
Hashimoto K, Ishii M, Komori S, Mitsuhashi H. Canine digitalis arrhythmia as a model for detecting Na-channel blocking antiarrhythmic drugs: a comparative study using other canine arrhythmia models and the new antiarrhythmic drugs, propafenone, tocainide, and SUN 1165. Heart Vessels 1985;1:29-35.
-
(1985)
Heart Vessels
, vol.1
, pp. 29-35
-
-
Hashimoto, K.1
Ishii, M.2
Komori, S.3
Mitsuhashi, H.4
-
5
-
-
0022777201
-
Electrophysiological actions of N-(2,6-dimethylphenyl)-8-pyrrolizidine-acetamide hydrochloride hemihydrate (SUN 1165), a new antiarrhythmic agent
-
Hattori Y, Inomata N, Aisaka K, Ishihara T. Electrophysiological actions of N-(2,6-dimethylphenyl)-8-pyrrolizidine-acetamide hydrochloride hemihydrate (SUN 1165), a new antiarrhythmic agent. J Cardiovasc Pharmacol 1986;8:998-1002.
-
(1986)
J Cardiovasc Pharmacol
, vol.8
, pp. 998-1002
-
-
Hattori, Y.1
Inomata, N.2
Aisaka, K.3
Ishihara, T.4
-
6
-
-
0023870343
-
Effect of SUN 1165, a new potent antiarrhythmic agent, on the kinetics of rate-dependent block of Na channels and ventricular conduction of extrasystoles
-
Hattori Y, Hidaka T, Aisaka K, Satoh F, Ishihara T. Effect of SUN 1165, a new potent antiarrhythmic agent, on the kinetics of rate-dependent block of Na channels and ventricular conduction of extrasystoles. J Cardiovasc Pharmacol 1988;11:407-12.
-
(1988)
J Cardiovasc Pharmacol
, vol.11
, pp. 407-412
-
-
Hattori, Y.1
Hidaka, T.2
Aisaka, K.3
Satoh, F.4
Ishihara, T.5
-
7
-
-
0023840215
-
Mechanism of inhibition by SUN 1165, a new Na channel blocking antiarrhythmic agent, of cardiac glycoside-induced triggered activity
-
Inomata N, Ishihara T. Mechanism of inhibition by SUN 1165, a new Na channel blocking antiarrhythmic agent, of cardiac glycoside-induced triggered activity. Eur J Pharmacol 1988;145:313-22.
-
(1988)
Eur J Pharmacol
, vol.145
, pp. 313-322
-
-
Inomata, N.1
Ishihara, T.2
-
8
-
-
0026594974
-
Effects of SUN-1165, N-(2,6-dimethylphenyl)-8-pyrrolizidine acetamide hydrochloride hemihydrate, a new class I antiarrhythmic drug, on ventricular arrhythmias, intraventricular conduction, and the refractory period in canine myocardial infarction
-
Hashimoto H, Satoh N, Nakashima M. Effects of SUN-1165, N-(2,6-dimethylphenyl)-8-pyrrolizidine acetamide hydrochloride hemihydrate, a new class I antiarrhythmic drug, on ventricular arrhythmias, intraventricular conduction, and the refractory period in canine myocardial infarction. J Cardiovasc Pharmacol 1992; 19:417-24.
-
(1992)
J Cardiovasc Pharmacol
, vol.19
, pp. 417-424
-
-
Hashimoto, H.1
Satoh, N.2
Nakashima, M.3
-
9
-
-
0027279362
-
Effects of pilsicainide on the atrial fibrillation threshold in guinea pig atria: A comparative study with disopyramide, lidocaine and flecainide
-
Inoue M, Inoue D, Ishibashi K, et al. Effects of pilsicainide on the atrial fibrillation threshold in guinea pig atria: a comparative study with disopyramide, lidocaine and flecainide. Jpn Heart J 1993;34: 301-12.
-
(1993)
Jpn Heart J
, vol.34
, pp. 301-312
-
-
Inoue, M.1
Inoue, D.2
Ishibashi, K.3
-
10
-
-
0024389286
-
Effects of N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate on the ventriculo-atrial conductivity of accessory pathways
-
Satoh S, Watanabe J, Keitoku M, et al. Effects of N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate on the ventriculo-atrial conductivity of accessory pathways. Arzneimittelforschung/Drug Res 1989;39:908-11.
-
(1989)
Arzneimittelforschung/Drug Res
, vol.39
, pp. 908-911
-
-
Satoh, S.1
Watanabe, J.2
Keitoku, M.3
-
11
-
-
0025809294
-
Suppressive effect of SUN1165 on supraventricular tachycardia
-
Terazawa T, Suzuki M, Goto T, et al. Suppressive effect of SUN1165 on supraventricular tachycardia. Am Heart J 1991;121:1437-44.
-
(1991)
Am Heart J
, vol.121
, pp. 1437-1444
-
-
Terazawa, T.1
Suzuki, M.2
Goto, T.3
-
12
-
-
0015542182
-
Premature atrial stimulation as a key to the understanding of sinoatrial conduction in man: Presentation of data and critical review of the literature
-
Strauss HC, Saroff AL, Bigger JT Jr, Giardina EG. Premature atrial stimulation as a key to the understanding of sinoatrial conduction in man: presentation of data and critical review of the literature. Circulation 1973;47:86-93.
-
(1973)
Circulation
, vol.47
, pp. 86-93
-
-
Strauss, H.C.1
Saroff, A.L.2
Bigger J.T., Jr.3
Giardina, E.G.4
-
13
-
-
0001298011
-
Phase 1 study of SUN 1165, a novel antiarrhythmic agent, No. 1: Single dose study
-
Nakashima M, Kanamaru M, Uematsu T, et al. Phase 1 study of SUN 1165, a novel antiarrhythmic agent, No. 1: single dose study. J Clin Ther Med 1989;5:661-78.
-
(1989)
J Clin Ther Med
, vol.5
, pp. 661-678
-
-
Nakashima, M.1
Kanamaru, M.2
Uematsu, T.3
-
14
-
-
0023722508
-
General pharmacological studies on N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate: 2nd communication: effect on the peripheral nervous system and peripheral organs
-
Hirotsu I, Kihara T, Hattori Y, et al. General pharmacological studies on N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate: 2nd communication: effect on the peripheral nervous system and peripheral organs. Arzneimittelforschung/Drug Res 1988;38:1410-7.
-
(1988)
Arzneimittelforschung/Drug Res
, vol.38
, pp. 1410-1417
-
-
Hirotsu, I.1
Kihara, T.2
Hattori, Y.3
-
15
-
-
0021929563
-
N-(2,6-Dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate (SUN 1165), a new antiarrhythmic agent: Effects on cardiac conduction
-
Hidaka T, Hamasaki S, Aisaka K, et al. N-(2,6-Dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate (SUN 1165), a new antiarrhythmic agent: effects on cardiac conduction. Arzneimittelforschung/Drug Res 1985;35:1381-6.
-
(1985)
Arzneimittelforschung/Drug Res
, vol.35
, pp. 1381-1386
-
-
Hidaka, T.1
Hamasaki, S.2
Aisaka, K.3
-
16
-
-
0023263149
-
SUN 1165: A new antiarrhythmic Na current blocker in ventricular myocytes of guinea-pig
-
Inomata N, Ishihara T, Akaike N. SUN 1165: a new antiarrhythmic Na current blocker in ventricular myocytes of guinea-pig. Comp Biochem Physiol C 1987;87:237-43.
-
(1987)
Comp Biochem Physiol C
, vol.87
, pp. 237-243
-
-
Inomata, N.1
Ishihara, T.2
Akaike, N.3
-
17
-
-
0023222744
-
Use-dependent blocking action of newly developed lidocaine-analogs on maximum rate of rise of action potentials in guinea pig papillary muscle
-
Toyama J, Kodama I, Kusunoki T, Ishihara T, Hattori Y, Yamada K. Use-dependent blocking action of newly developed lidocaine-analogs on maximum rate of rise of action potentials in guinea pig papillary muscle. Jpn Heart J 1987;28:273-85.
-
(1987)
Jpn Heart J
, vol.28
, pp. 273-285
-
-
Toyama, J.1
Kodama, I.2
Kusunoki, T.3
Ishihara, T.4
Hattori, Y.5
Yamada, K.6
-
18
-
-
0020676610
-
Cardiac electrophysiologic effects of flecainide acetate for paroxysmal reentrant junctional tachycardias
-
Hellestrand KJ, Nathan AW, Bexton RS, Spurrell RAJ, Cam AJ. Cardiac electrophysiologic effects of flecainide acetate for paroxysmal reentrant junctional tachycardias. Am J Cardiol 1983;51:770-6.
-
(1983)
Am J Cardiol
, vol.51
, pp. 770-776
-
-
Hellestrand, K.J.1
Nathan, A.W.2
Bexton, R.S.3
Spurrell, R.A.J.4
Cam, A.J.5
-
19
-
-
0019995921
-
Acute electrophysiological effects of flecainide acetate on cardiac conduction and refractoriness in man
-
Hellestrand KJ, Bexton RS, Nathan AW, Spurrell RAJ, Cam AJ. Acute electrophysiological effects of flecainide acetate on cardiac conduction and refractoriness in man. Br Heart J 1982;48:140-8.
-
(1982)
Br Heart J
, vol.48
, pp. 140-148
-
-
Hellestrand, K.J.1
Bexton, R.S.2
Nathan, A.W.3
Spurrell, R.A.J.4
Cam, A.J.5
-
20
-
-
0020533212
-
Effects of flecainide on electrophysiologic properties of accessory pathways in the Wolff-Parkinson-White syndrome
-
Neuss H, Buss J, Schlepper M, et al. Effects of flecainide on electrophysiologic properties of accessory pathways in the Wolff-Parkinson-White syndrome. Eur Heart J 1983;4:347-53.
-
(1983)
Eur Heart J
, vol.4
, pp. 347-353
-
-
Neuss, H.1
Buss, J.2
Schlepper, M.3
-
21
-
-
0024589672
-
Electrophysiologic effects of intravenous propafenone in Wolff-Parkinson-White syndrome
-
Dubuc M, Kus T, Campa MA, Lambert C, Rosengarten M, Shenesta M. Electrophysiologic effects of intravenous propafenone in Wolff-Parkinson-White syndrome. Am Heart J 1989;117:370-6.
-
(1989)
Am Heart J
, vol.117
, pp. 370-376
-
-
Dubuc, M.1
Kus, T.2
Campa, M.A.3
Lambert, C.4
Rosengarten, M.5
Shenesta, M.6
-
22
-
-
0023690906
-
Flecainide acetate for treatment of bypass tract mediated reentrant tachycardia
-
Zee-Cheng CS, Kim SS, Ruffy R. Flecainide acetate for treatment of bypass tract mediated reentrant tachycardia. Am J Cardiol 1988; 62:23D-8D.
-
(1988)
Am J Cardiol
, vol.62
-
-
Zee-Cheng, C.S.1
Kim, S.S.2
Ruffy, R.3
-
23
-
-
0018574316
-
Incidence, determinants and significance of fixed retrograde conduction in the region of the atrioventricular node
-
Gomes JA, Dhatt MS, Damato AN, Akhtar M, Holder CA. Incidence, determinants and significance of fixed retrograde conduction in the region of the atrioventricular node. Am J Cardiol 1979;44:1089-98.
-
(1979)
Am J Cardiol
, vol.44
, pp. 1089-1098
-
-
Gomes, J.A.1
Dhatt, M.S.2
Damato, A.N.3
Akhtar, M.4
Holder, C.A.5
-
24
-
-
0018771001
-
Electrophysiologic evidence for selective retrograde utilization of a specialized conducting system in atrioventricular nodal reentrant tachycardia
-
Gomes JA, Dhatt MS, Rubenson DS, Damato AN. Electrophysiologic evidence for selective retrograde utilization of a specialized conducting system in atrioventricular nodal reentrant tachycardia. Am J Cardiol 1979;43:687-98.
-
(1979)
Am J Cardiol
, vol.43
, pp. 687-698
-
-
Gomes, J.A.1
Dhatt, M.S.2
Rubenson, D.S.3
Damato, A.N.4
-
25
-
-
0020049662
-
Electrophysiologic effects of disopyramide phosphate in patients with Wolff-Parkinson-White syndrome
-
Kerr CR, Prystowsky EN, Smith WM, Cook L, Gallagher JJ. Electrophysiologic effects of disopyramide phosphate in patients with Wolff-Parkinson-White syndrome. Circulation 1982;65: 869-78.
-
(1982)
Circulation
, vol.65
, pp. 869-878
-
-
Kerr, C.R.1
Prystowsky, E.N.2
Smith, W.M.3
Cook, L.4
Gallagher, J.J.5
-
26
-
-
0017760991
-
Effect of verapamil studied by programmed electrical stimulation of the heart in patients with paroxysmal reentrant supraventricular tachycardia
-
Wellens HJJ, Tan SL, Bar FWH, Duren DR, Lie KI, Dohmen HM. Effect of verapamil studied by programmed electrical stimulation of the heart in patients with paroxysmal reentrant supraventricular tachycardia. Br Heart J 1977;39:1058-66.
-
(1977)
Br Heart J
, vol.39
, pp. 1058-1066
-
-
Wellens, H.J.J.1
Tan, S.L.2
Bar, F.W.H.3
Duren, D.R.4
Lie, K.I.5
Dohmen, H.M.6
-
27
-
-
0029993521
-
Clinical effects and pharmacokinetics of a single oral dose of pirmenol hydrochloride
-
Atarashi H, Kuruma A, Ino T, Hirayama Y, Saitoh H, Hayakawa H. Clinical effects and pharmacokinetics of a single oral dose of pirmenol hydrochloride. J Cardiovasc Pharmacol 1996;27:556-62.
-
(1996)
J Cardiovasc Pharmacol
, vol.27
, pp. 556-562
-
-
Atarashi, H.1
Kuruma, A.2
Ino, T.3
Hirayama, Y.4
Saitoh, H.5
Hayakawa, H.6
-
28
-
-
0020616012
-
Paradoxical effects of procainamide-facilitation of the induction of sustained reciprocating tachycardia after procainamide administration in Wolff-Parkinson-White syndrome
-
Fukatani M, Kiya F, Yano K, Hashiba K. Paradoxical effects of procainamide-facilitation of the induction of sustained reciprocating tachycardia after procainamide administration in Wolff-Parkinson-White syndrome. Jpn Circ J 1983;47:124-31.
-
(1983)
Jpn Circ J
, vol.47
, pp. 124-131
-
-
Fukatani, M.1
Kiya, F.2
Yano, K.3
Hashiba, K.4
-
29
-
-
0024321898
-
Preliminary report: Effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction
-
The Cardiac Arrhythmia Suppression Trial (CAST) Investigators. Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction. N Engl J Med 1989;321:406-12.
-
(1989)
N Engl J Med
, vol.321
, pp. 406-412
-
-
-
30
-
-
0026011647
-
Mortality and morbidity in patients receiving encainide, flecainide or placebo
-
The Cardiac Arrhythmia Suppression Trial (CAST) Investigators. Mortality and morbidity in patients receiving encainide, flecainide or placebo. N Engl J Med 1991;324:781-8.
-
(1991)
N Engl J Med
, vol.324
, pp. 781-788
-
-
-
31
-
-
0023074138
-
Influence of left ventricular dysfunction on flecainide therapy
-
de Paola AA, Horowitz LN, Morganroth J, et al. Influence of left ventricular dysfunction on flecainide therapy. J Am Coll Cardiol 1987;9:163-8.
-
(1987)
J Am Coll Cardiol
, vol.9
, pp. 163-168
-
-
De Paola, A.A.1
Horowitz, L.N.2
Morganroth, J.3
-
32
-
-
0023731189
-
General pharmacological studies on N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate: 3rd communication: effect on cardiovascular system
-
Aisaka K, Hidaka T, Hattori Y, Inomata N, Ishihara T, Satoh F. General pharmacological studies on N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate: 3rd communication: effect on cardiovascular system. Arzneimittelforschung/Drug Res 1988;38:1417-25.
-
(1988)
Arzneimittelforschung/Drug Res
, vol.38
, pp. 1417-1425
-
-
Aisaka, K.1
Hidaka, T.2
Hattori, Y.3
Inomata, N.4
Ishihara, T.5
Satoh, F.6
-
33
-
-
0030048292
-
Mechanisms of negative inotropic effects of class 1c antiarrhythmic agents: Comparative study of the effects of flecainide and pilsicainide on intracellular calcium handling in dog ventricular myocardium
-
Kihara Y, Inoko M, Hatakeyama N, Momose Y, Sasayama S. Mechanisms of negative inotropic effects of class 1c antiarrhythmic agents: comparative study of the effects of flecainide and pilsicainide on intracellular calcium handling in dog ventricular myocardium. J Cardiovasc Pharmacol 1996;27:42-51.
-
(1996)
J Cardiovasc Pharmacol
, vol.27
, pp. 42-51
-
-
Kihara, Y.1
Inoko, M.2
Hatakeyama, N.3
Momose, Y.4
Sasayama, S.5
|