Mechanism of benefit of negative inotropes in obstructive hypertrophic cardiomyopathy

Circulation

Volumn 97, Issue 1, 1998, Pages 41-47

  Sherrid, Mark V ^a,b   Pearle, Gretchen ^a   Gunsburg, David Z ^a  

^a College of Physicians and Surgeons ^*  (United States)

^b ST LUKE S ROOSEVELT HOSPITAL CENTER   (United States)

Author keywords

Cardiomyopathy; Drugs; Echocardiography; Hypertrophy

Indexed keywords

DISOPYRAMIDE; METOPROLOL; VERAPAMIL;

ADULT; AGED; ARTICLE; BLOOD FLOW VELOCITY; CLINICAL ARTICLE; CORONARY ARTERY BLOOD FLOW; DOPPLER ECHOCARDIOGRAPHY; DRUG EFFECT; FEMALE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE OUTFLOW TRACT; HUMAN; HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY; INOTROPISM; MALE; PRIORITY JOURNAL;

EID: 0031984468     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.97.1.41     Document Type: Article

References (37)

1. Harrison DC, Braunwald E, Glick G, Mason DT, Chidsey CA, Ross J Jr. Effects of beta adrenergic blockade on the circulation with particular reference to observations in patients with hypertrophic subaortic stenosis. Circulation. 1964;29:84-98.
2. Goodwin JF, Shah PM, Oakley CM, Cohen J, Yipintsoi T, Pocock W. The clinical pharmacology of hypertrophic obstructive cardiomyopathy. In: Wolstenholme GEW, O'Conner M, eds. Cardiomyopathies. Boston, Mass: Little, Brown and Co; 1964:189-213.
3. Rosing DR, Kent KM, Borer JS, Seides SF, Maron BJ, Epstein SE. Verapamil therapy: a new approach to the pharmacologic treatment of hypertrophic cardiomyopathy, I: hemodynamic effects. Circulation. 1979;60:1201-1207.
4. Pollick C. Muscular subaortic stenosis: hemodynamic and clinical improvement after disopyramide. N Engl J Med. 1982;307:997-999.
5. Stenson RE, Flamm MD Jr, Harrison DC, Hancock EW. Hypertrophic subaortic stenosis: clinical hemodynamic effects of long-term propranolol therapy. Am J Cardiol. 1973;31:763-773.
6. Rosing DR, Condit JR, Maron BJ, Kent KM, Leon MB, Bonow RO, Lipson LC, Epstein SE. Verapamil therapy: a new approach to the pharmacologic treatment of hypertrophic cardiomyopathy, III: effects of long-term administration. Am J Cardiol. 1981;48:545-553.
7. Pollick C. Disopyramide in hypertrophic cardiomyopathy, II: noninvasive assessment after oral administration. Am J Cardiol. 1988;62:1252-1255.
8. Henry WL, Clark CE, Griffith JM, Epstein SE. Mechanism of left ventricular outflow obstruction in patients with obstructive asymmetric septal hypertrophy (idiopathic hypertrophic subaortic stenosis). Am J Cardiol. 1975;35:337-345.
9. Popp R, Harrison DC. Ultrasound in the diagnosis and evaluation of therapy of idiopathic hypertrophic subaortic stenosis. Circulation. 1969;40:905-914.
10. Shah PM, Gramiak R, Adelman AG, Wigle ED. Echocardiographic assessment of the effects of surgery and propranolol on the dynamics of outflow obstruction in hypertrophic subaortic stenosis. Circulation. 1972;45:516-521.
11. Maron BJ, Epstein SE. Hypertrophic cardiomyopathy: a discussion of nomenclature. Am J Cardiol. 1979;43:1242-1244.
12. Sasson Z, Yock PG, Hatle LK, Alderman EL, Popp RL. Doppler echocardiographic determination of the pressure gradient in hypertrophic cardiomyopathy. J Am Coll Cardiol. 1988;11:752-756.
13. Pollick C. Disopyramide in hypertrophic cardiomyopathy: noninvasive assessment after oral administration. Am J Cardiol. 1988;62:1252-1255.
14. Sherrid M, Delia E, Dwyer E. Oral disopyramide therapy for obstructive hypertrophic cardiomyopathy. Am J Cardiol. 1988;62:1085-1088.
15. Rosing DR, Kent KM, Maron BJ, Epstein SE. Verapamil therapy: a new approach to the pharmacologic treatment of hypertrophic cardiomyopathy, II: effects on exercise capacity and symptomatic status. Circulation. 1979;60:1208-1213.
16. Jiang L, Levine RA, King ME, Weyman AE. An integrated mechanism for systolic anterior motion of the mitral valve in hypertrophic cardiomyopathy based on echocardiographic observations. Am Heart J. 1987;113:633-644.
17. Sherrid MV, Chu CK, Delia E, Mogtader A, Dwyer EM Jr. An echocardiographic study of the fluid mechanics of obstruction in hypertrophic cardiomyopathy. J Am Coll Cardiol. 1993;22:816-825.
18. Gardin JM, Iseri LT, Elkayam U, Tobis J, Childs W, Burn CS, Henry WL. Evaluation of dilated cardiomyopathy by pulsed Doppler echocardiography. Am Heart J. 1983;106:1057-1065.
19. Wallmeyer K, Wann LS, Sagar KB, Kalbfleisch J, Klopfenstein HS. The influence of preload and heart rate on Doppler echocardiographic indexes of left ventricular performance: comparison with invasive indexes in an experimental preparation. Circulation. 1986;74:181-186.
20. Kupari M, Koskinen P. Systolic flow velocity profile in the left ventricular outflow tract in persons free of heart disease. Am J Cardiol. 1993;72:1172-1178.
21. Pasipoularides A. Clinical assessment of ventricular ejection dynamics with and without outflow obstruction. J Am Coll Cardiol. 1990;15:859-882.
22. Lewis RP, Rittgers SE, Forester WF, Boudoulas H. A critical review of the systolic time intervals. Circulation. 1977;56:146-158.
23. Helmcke F, Nanda NC, Hsiung MC, Soto B, Adey CK, Goyal RG, Gatewood RP. Color Doppler assessment of mitral regurgitation with orthogonal planes. Circulation. 1987;75:175-183.
24. Sasson Z, Henderson M, Wilansky S, Rakowski H, Wigle ED. Causal relation between the pressure gradient and left ventricular ejection time in hypertrophic cardiomyopathy. J Am Coll Cardiol. 1989;13:1275-1279.
25. Wigle ED, Rakowski H, Kimball BP, Williams WG. Hypertrophic cardiomyopathy: clinical spectrum and treatment. Circulation. 1995;92:1680-1692.
26. Pollick C, Morgan C, Gilbert B, Rakowski H, Wigle ED. Muscular subaortic stenosis: the temporal relationship between systolic motion of the anterior mitral leaflet and the pressure gradient. Circulation. 1982;66:1087-4094.
27. Pollick C, Rakowski H, Wigle ED. Muscular subaortic stenosis: the quantitative relationship between systolic anterior motion and the pressure gradient. Circulation. 1984;69:43-49.
28. Yock PG, Hade L, Popp RL. Patterns and timing of Doppler-detected intracavitary and aortic flow in hypertrophic cardiomyopathy. J Am Coll Cardiol. 1986;8:1047-1058.
29. Lin CS, Chen KS, Lin MC, Fu MC, Tang SM. The relationship between systolic anterior motion of the mitral valve and the left ventricular outflow Doppler in hypertrophic cardiomyopathy. Am Heart J. 1991;122:1671-1682.
30. Sherrid MV, Gunsburg D, Pearle G. Midsystolic drop in left ventricular ejection velocity in obstructive hypertropic cardiomyopathy: the lobster claw abnormality. J Am Soc Echocardiogr. 1997;10:707-712.
31. Fox R, McDonald A. Introduction to Fluid Mechanics. 3rd ed. New York, NY: Wiley and Sons; 1985:459-473.
32. Cape EG, Simons D, Jimoh A, Weyman AE, Yognathan AP, Levine RA. Chordal geometry determines the shape and extent of systolic anterior motion: in vitro studies. J Am Coll Cardiol. 1989;13:1438-1448.
33. Salisbury P, Cross C, Rieben PA. Chorda tendinea tension. Am J Physiol. 1963;205:385-392.
34. Murgo JP, Alter BR, Dorethy JF, Altobelli SA, McGranahan GM Jr. Dynamics of left ventricular ejection in obstructive and non obstructive hypertrophic cardiomyopathy. J Clin Invest. 1980;66:1369-1382.
35. Pierce GE, Morrow AG, Braunwald E. Idiopathic hypertrophic subaortic stenosis: intraoperative studies of the mechanism of obstruction and its hemodynamic consequences. Circulation. 1964;29 (suppl 4):152-174.
36. Hernandez RR, Greenfield JC Jr, McCall BW. Pressure-flow studies in hypertrophic subaortic stenosis. J Clin Invest. 1964;43:401-407.
37. Mason DT, Braunwald E, Ross J Jr, Morrow AG. Diagnostic value of the first and second derivatives of the arterial pressure pulse in aortic valve disease and in hypertrophic subaortic stenosis. Circulation. 1964;30:90-100.