Biological diagnosis of heparin-induced thrombocytopenia. Comparison between platelet aggregation test and 'heparin-platelet factor 4' ELISA in 100 patients;DIAGNOSTIC BIOLOGIQUE DE LA THROMBOPENIE IMMUNO-ALLERGIQUE A L'HEPARINE (TIH). COMPARAISON DES TESTS D'AGREGATION PLAQUETTAIRE ET ELISA 'FACTEUR 4 PLAQUETTAIRE-HEPARINE' (HPIA) CHEZ 100 PATIENTS

Feuillets de Biologie

Volumn 39, Issue 220, 1998, Pages 9-16

  Elalamy, I ^a   Potevin, F ^a   Lecrubier, C ^a   Amiral, J ^b   Marie, J P ^a   Samama, M M ^a  

^a HÔTEL DIEU   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; DRUG ANTIBODY; HEPARIN;

ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST; DIAGNOSTIC VALUE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; MAJOR CLINICAL STUDY; THROMBOCYTOPENIA;

EID: 0031983730     PISSN: 04282779     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. AMIRAL J., BRIDEY F., DREYFUS M., VISSAC A.M., FRESSINAUD E., WOLF M., MEYER D. - Platelet-factor 4 complexed to heparin is the target for antibodies generated in heparin-induced thrombocytopenia. Thromb Haemost. 1992; 68: 95-96.
2. AMIRAL J., MARFAING-KOBA A., WOLF M., VISSAC A.M., BOYER-NEUMANN C., PONCZ M., MEYER D. - Auto-anticorps dirigés contre l'IL-8 ou le NAP-2 dans certaines thrombopénies induites par l'héparine. GEHT Hémostase et Neurologie Paris (abst.), 1986.
3. ASTER R.H. - Heparin-induced-thrombocytopenia and thrombosis. N. Engl. J. Med. 1995; 332: 1374-1376.
4. BOSHKOV L.K., WARKENTIN T.E., HAYWARD C.P., ANDREW M. - Heparin-induced thrombocytopenia and thrombosis: clinical and laboratories studies. Br. J. Haematol. 1993; 84: 332-328.
5. CAZENAVE J.P., HEMMENDINGER S., BERETZ A., SUTTER-BAY A., LAUNAY J.M. - L'agrégation plaquettaire ; outil d'investigation clinique et d' étude pharmacologique Méthodologie. Ann. Biol Clin. 1983; 41: 167-179.
6. CHONG B.H., BURGESS J., ISMAIL F. - The clinical usefulness of the platelet aggregation test for the diagnosis of heparin-induced-thrombocytopenia. Thromb. Haemost. 1993; 69: 344-350.
7. CHONG B.H. - Heparin-induced thrombocytopenia. Annotation. Br. J. Haematol 1995; 89: 431-439.
8. ELALAMY I., POTEVIN F., LECRUBIER C., BARA L., MARIE J.P., SAMAMA M.M. - A fatal low molecular weight heparin-associated thrombocytopenia after hip surgery: possible usefulness of PF4-heparin ELISA test. Blood Coagulation and Fibrinolysis 1996; 7: 665-671.
9. FAVIER R., RENESTO P., BAUDET V., MOREL M.C., KAPLAN C., TOULEC D., CHIGNARD M., LECOMPTE T - Mechanisms of platelet activation induced by a CD 41 monoclonal antibody PL249 : comparison with A1B6. Fibrinolysis 1990; 4 (suppl1): 14.
10. GEROTZIAFAS G., ELALAMY I., LECRUBIER C., LEBRAZI J., KAPLAN C., SAMAMA M.M., LECOMPTE T. - Immunological human platelet activation induced by two monoclonal antibodies: PI249 and Leo A1. (soumis).
11. GOAD K.E., HORNE Mc D.K. and GRALNICK H.R. - Pentosan-induced thrombocytopenia: support for an immune complex mechanism. Br. J. Haematol. 1994; 88: 803-808.
12. GREINACHER A., MICHELS I., KIEFEL V., MUELLER-ECKHARDT C. - A rapid and sensitive test for diagnosing heparin-associated thrombocytopenia. Thromb. Haemost. 1991; 66: 734-736.
13. GREINACHER A., MICHELS I., LIEBENHOFF U., PRESEK P. and MUELLER-ECKHARDT C. - Heparin-associated thrombocytopenia: immune complexes are attached to the platelet membrane by the negative charge of highly sulphated oligosaccarides. Br. J. Haematol. 1993; 84: 711-716.
14. GREINACHER A., AMIRAL J., DUMMEL V., VISSAC V., KIEFEL V., MUELLER-ECKARDT C. - Laboratory diagnosis of heparin-associated thrombocytopenia and comparison of platelet aggregation, heparin-induced platelet activation, and platelet-factor4/heparin enzyme-linked immunosorbent assay. Transfusion. 1994; 34: 381-385.
15. HACH-WUNDERLE V., KAINER K., SALZMANN G., MULLER-BERGHAUS G., PÖTZSCH B. - Heparin-associated thrombosis despite normal platelets count. Ann. Hematol. 1995; 70 suppl 1, A 56 (abst.).
16. HIRSH J., RASCHKE R., WARKENTIN T.E., DALEN J.E., DEYKIN D., POLLER L. - Heparin: Mechanisms of action, pharmacocinetic, dosing considerations, monitoring, efficacy, and safety Fourth ACCP consensus conference on antithrombotic therapy. Chest. 1995; 108: 257S-259S.
17. HORNE M.K., CHAO E.S. - The effect of molecular weight on heparin binding to platelets. Br. J. Haematol. 1990; 74: 306-312.
18. LEBRAZI J., HELFT G., MIRSHAHI M., SAMAMA M M., LECOMPTE T. - L'agrégation plaquettaire induite par les IgGs anti-streptokinase nécessite l'interaction du domaine Fc avec le récepteur plaquettaire FcgRII/CD32. Nouv. Rev. Fr. Hématol 1994; 36: 29.
19. LECRUBIER C., LECOMPTE T., POTEVIN F., HORELLOU M.H., CONARD J., SAMAMA M.M. (1987) - Heparin-induced-thrombocytopenia: methodological and diagnostic problems and therapeutic aspects (a study of 26 cases). J. Mal. Vasc. 1987; 12: 128-132.
20. MESSMORE H.L., GRIFFIN B., KOZA M., SEGHATCHIAN J., FAREED J., COYNE E. - Interaction of heparinoids with platelets: comparison with heparin and low molecular weight heparins. Semin. Thromb. Hemost. 1991; 17 suppl.1, 57-59.
21. NGUYEN P., LECOMPTE T. et le groupe d'étude sur l'hémostase et la thrombose heparin-induced-thrombocytopenia: a survey of tests employed and attitudes in haemotology laboratories. Nouv. Rev. Fr. Haematol. 1994; 36: 353-357.
22. NGUYEN P., DROULLÉ C., POTRON G. - Comparison between platelet factor4/heparin complexes ELISA and platelet aggregation test in heparin-induced thrombocytopenia. Thromb. Haemost. 1995; 74: 793-810.
23. Recommandations du GEHT sur l'utilisation des traitements antithrombotiques (heparines) en pratique médicale courante. Sang Thrombose Vaisseaux. 1991; 3 suppl 5, 4-10.
24. SHERIDAN D., CARTER C., KELTON J.G. - A diagnostic test for heparin-induced thrombocytopenia. Blood. 1986; 67: 27-30.
25. STEWART M.W., ETCHES W.S., BOSHKOV L.K., GORDON P.A. - Heparin-induced thrombocytopenia: an improved method of detection based on lumi-aggregometry. Br. J. Haematol, (1995), 91, 173-177.
26. VISENTIN G.P., FORD S.E., SCOTT J.P., ASTER R.H - Antibodies from patients with heparin-induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells. J. Clin. Invest. 1994, 93, 81-88.
27. WARKENTIN T.E., KELTON J.G. - Heparin-induced thrombocytopenia. Prog. Hemost. Thromb. 1991, 10: 1-34.
28. WARKENTIN T.E., HAYWARD C.P.M., SMITH C.M , KELLY P.M., KELTON J.G. - Determinants of donor platelet variability when testing for heparin-induced thrombocytopenia. J. Lab. Clin. Med, 1992, 120, 371-379.
29. WARKENTIN T.E., HAYWARD C.P.M., BOSHKOV L.K., SANTOS A.V., SHEPPARD J.-A.I., BODE A.P., KELTON J.G. - Sera from patients with heparin-induced thrombocytopenia generate platelet-derived microparticles with procoagulant activity: an explanation for the thrombotic complications of heparin-induced thrombocytopenia. Blood. 1994; 84: 3691-3699.
30. WARKENTIN T.E., LEVINE M.N., HIRSH J., HORSEWOOD P., ROBERTS R.S., GENT M., KELTON J.G. - Hepa-rin-induced thrombocytopenia in patients treated with lowmolecular-weight heparin or unfractionated heparin. N. Engl. J. Med. 1995, 332, 1330-1335.
31. WARKENTIN T.E., HORSEWOOD P., HAYWARD C P.M., KELTON J.G. - The epitope specificity of heparin-induced thrombocytopenia. Br. J. Haematol. 1996, 95, 161-167.