Involvement of immunopathogenic mechanisms in a spontaneously occurring glomerulopathy in mice

Nephron

Volumn 78, Issue 1, 1998, Pages 63-72

  Chen, Ann ^a   Sheu, Lai Fa ^a   Chou, Wei Yuan ^b   Ho, Yat Sen ^c   Lin, Yu Feng ^a   Lin, Fu Gong ^b   Lee, Wei Hwa ^a  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

C3; Electron dense deposits; Glomerulosclerosis; IgM nephropathy; Immune complex; Proteinuria

Indexed keywords

COMPLEMENT COMPONENT C3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPLEMENT FIXATION; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; GLOMERULOPATHY; GLOMERULOSCLEROSIS; IMMUNE COMPLEX DEPOSITION; IMMUNOPATHOGENESIS; LYMPHOCYTIC INFILTRATION; MESANGIUM; MOUSE; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; PROTEINURIA;

ANIMALS; BLOOD UREA NITROGEN; COMPLEMENT C3; CREATININE; FEMALE; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; HEMATURIA; IMMUNOGLOBULINS; KIDNEY; KIDNEY GLOMERULUS; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON; NITRATES; NITRITES; PROTEINURIA; SUPEROXIDES;

EID: 0031983634     PISSN: 00282766     EISSN: None     Source Type: Journal    
DOI: 10.1159/000044884     Document Type: Article

References (6)

1. Elema JD, Arends A: Focal and segmental glomerular hyalinosis and sclerosis in the rat. Lab Invest 1975;33:554-561.
2. Kraus B, Cain H: Über eine spontane Nephropathie bei Wistar-Ratten. Virchows Arch 1974;363:343-358.
3. Couser WG, Stilmant MM: Mesangial lesions and focal glomerular sclerosis in the aging rat. Lab Invest 1975;33:491-501.
4. Bolton WK, Benton FR, Maclay JG, Sturgill BC: Spontaneous glomerular sclerosis in aging Sprague-Dawley rats. I. Lesions associated with mesangial IgM deposits. Am J Pathol 176;85;277-302.
5. Kreisberg JI, Karnovsky MJ: Focal glomerular sclerosis in the fawn-hooded rat. Am J Pathol 1978;92:637-652.
6. Brenner BM, Meyer TW, Hosteller TH: Dietary protein intake and the progressive nature of kidney disease: The role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation and intrinsic renal disease. N Engl J Med 1982;307:651-659.