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Volumn 14, Issue 1, 1998, Pages 27-36

Arylamine N-acetyltransferases: Genetic polymorphism and susceptibility to xenobiotics;LES ARYLAMINE N-ACETYLTRANSFERASES: DU POLYMORPHISME GENETIQUE A LA SUSCEPTIBILITE AUX XENOBIOTIQUES

Author keywords

[No Author keywords available]

Indexed keywords

ARYLAMINE ACETYLTRANSFERASE; DRUG METABOLIZING ENZYME; XENOBIOTIC AGENT;

EID: 0031983614     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.4267/10608/880     Document Type: Review
Times cited : (5)

References (41)
  • 1
    • 0030995879 scopus 로고    scopus 로고
    • Molecular mechanisms of genetic polymorphisms of drug metabolism
    • Meyer UA, Zanger UM. Molecular mechanisms of genetic polymorphisms of drug metabolism. Annu Rev Pharmacol Toxicol 1997 ; 37 : 269-96.
    • (1997) Annu Rev Pharmacol Toxicol , vol.37 , pp. 269-296
    • Meyer, U.A.1    Zanger, U.M.2
  • 2
    • 0031035007 scopus 로고    scopus 로고
    • Polymorphisms in drug-metabolizing enzymes : What is their clinical relevance and why do they exist?
    • Nebert DW. Polymorphisms in drug-metabolizing enzymes : what is their clinical relevance and why do they exist? Am J Hum Genet 1997 ; 60 : 265-71.
    • (1997) Am J Hum Genet , vol.60 , pp. 265-271
    • Nebert, D.W.1
  • 3
    • 0002202499 scopus 로고
    • N-acetyltransferase
    • Kalow W, ed. New York : Pergamon Press
    • Evans DAP. N-acetyltransferase. In : Kalow W, ed. Pharmacogenetics of Drug Metabolism. New York : Pergamon Press, 1992 : 95-178.
    • (1992) Pharmacogenetics of Drug Metabolism , pp. 95-178
    • Evans, D.A.P.1
  • 4
    • 0025231840 scopus 로고
    • Acetylation pharmacogenetics. the slow acetylator phenotype is caused by decreased or absent arylamine N-acetyltransferase in human liver
    • Grant DM, Mörike K, Eichelbaum M, Meyer UA. Acetylation pharmacogenetics. The slow acetylator phenotype is caused by decreased or absent arylamine N-acetyltransferase in human liver. J Clin Invest 1990 ; 85 : 968-72.
    • (1990) J Clin Invest , vol.85 , pp. 968-972
    • Grant, D.M.1    Mörike, K.2    Eichelbaum, M.3    Meyer, U.A.4
  • 5
    • 6844262810 scopus 로고
    • Polymorphisme génétique du métabolisme hépatique des médicaments
    • Larrey D. Polymorphisme génétique du métabolisme hépatique des médicaments. Med Sci 1986 ; 2 : 364-72.
    • (1986) Med Sci , vol.2 , pp. 364-372
    • Larrey, D.1
  • 6
    • 6844228266 scopus 로고
    • Les cytochromes p450 hépatiques humains
    • Beaune P. Les cytochromes p450 hépatiques humains. Med Sci 1986 ; 2 : 358-63.
    • (1986) Med Sci , vol.2 , pp. 358-363
    • Beaune, P.1
  • 7
    • 0026078504 scopus 로고
    • Predominance of slow acetylator phenotype among patients with sulfonamide hypersensitivity reactions
    • Rieder MJ, Shear NH, Kanee A, Tang BK. Predominance of slow acetylator phenotype among patients with sulfonamide hypersensitivity reactions. Clin Pharmacol Ther 1991 ; 49 : 13-7.
    • (1991) Clin Pharmacol Ther , vol.49 , pp. 13-17
    • Rieder, M.J.1    Shear, N.H.2    Kanee, A.3    Tang, B.K.4
  • 8
    • 0025967717 scopus 로고
    • Monomorphic and polymorphic human arylamine N-acetyltransferases : A comparison of liver isozymes and expressed products of two cloned genes
    • Grant DM, Blum M, Beer M, Meyer UA. Monomorphic and polymorphic human arylamine N-acetyltransferases : a comparison of liver isozymes and expressed products of two cloned genes. Mol Pharmacol 1991 ; 39 : 184-91.
    • (1991) Mol Pharmacol , vol.39 , pp. 184-191
    • Grant, D.M.1    Blum, M.2    Beer, M.3    Meyer, U.A.4
  • 10
    • 0029812630 scopus 로고    scopus 로고
    • Immunochemical detection of arylamine N-acetyltransferase in normal and neoplastic bladder
    • Stanley LA, Coroneos E, Cuff R, Hickman D, Ward A, Sim E. Immunochemical detection of arylamine N-acetyltransferase in normal and neoplastic bladder. J Histochem Cylochem 1996 ; 44 : 1059-67.
    • (1996) J Histochem Cylochem , vol.44 , pp. 1059-1067
    • Stanley, L.A.1    Coroneos, E.2    Cuff, R.3    Hickman, D.4    Ward, A.5    Sim, E.6
  • 11
    • 0026335694 scopus 로고
    • Expression of monomorphic arylamine N-acetyltransferase (NAT1) in human leukocytes
    • Cribb AE, Grant DM, Miller MA, Spielberg SP. Expression of monomorphic arylamine N-acetyltransferase (NAT1) in human leukocytes. J Pharmacol Exp Ther 1991 ; 259 : 1241-6.
    • (1991) J Pharmacol Exp Ther , vol.259 , pp. 1241-1246
    • Cribb, A.E.1    Grant, D.M.2    Miller, M.A.3    Spielberg, S.P.4
  • 12
    • 0028291988 scopus 로고
    • Arylamine N-acetyltransferase activity of the human placenta
    • Derewlany LO, Knie B, Koren G. Arylamine N-acetyltransferase activity of the human placenta. J Pharmacol Exp Ther 1994 ; 269 : 756-60.
    • (1994) J Pharmacol Exp Ther , vol.269 , pp. 756-760
    • Derewlany, L.O.1    Knie, B.2    Koren, G.3
  • 13
    • 0029934427 scopus 로고    scopus 로고
    • N-acetyltransferase expression and metabolic activation of the food-derived heterocyclic amines in the human mammary gland
    • Sadrieh N, Davis CD, Snyderwine EG. N-acetyltransferase expression and metabolic activation of the food-derived heterocyclic amines in the human mammary gland. Cancer Res 1996 ; 56 : 2683-7.
    • (1996) Cancer Res , vol.56 , pp. 2683-2687
    • Sadrieh, N.1    Davis, C.D.2    Snyderwine, E.G.3
  • 16
    • 0022600724 scopus 로고
    • Acetyltransferase in humans : Development and tissue distribution
    • Pacifici GM, Bencini C, Rane A. Acetyltransferase in humans : development and tissue distribution. Pharmacology 1986 ; 32 : 283-91.
    • (1986) Pharmacology , vol.32 , pp. 283-291
    • Pacifici, G.M.1    Bencini, C.2    Rane, A.3
  • 17
    • 0026648960 scopus 로고
    • 68 in the catalytic mechanism of polymorphic human NAT2
    • 68 in the catalytic mechanism of polymorphic human NAT2. J Biol Chem 1992 ; 267 : 7381-5.
    • (1992) J Biol Chem , vol.267 , pp. 7381-7385
    • Dupret, J.M.1    Grant, D.M.2
  • 19
    • 0028043708 scopus 로고
    • Structure-function studies of human N-acetyltransferases NAT1 and NAT2. Functional analysis of recombinant NAT1/NAT2 chimeras expressed in E. Coli
    • Dupret JM, Goodfellow GH, Janezic SA, Grant DM. Structure-function studies of human N-acetyltransferases NAT1 and NAT2. Functional analysis of recombinant NAT1/NAT2 chimeras expressed in E. Coli. J Biol Chem 1994 ; 269 : 26830-5.
    • (1994) J Biol Chem , vol.269 , pp. 26830-26835
    • Dupret, J.M.1    Goodfellow, G.H.2    Janezic, S.A.3    Grant, D.M.4
  • 20
    • 0021151820 scopus 로고
    • A simple test for acetylator phenotype using caffeine
    • Grant DM, Tang BK, Kalow W. A simple test for acetylator phenotype using caffeine. Br J Clin Pharmacol 1984 ; 17 : 459-64.
    • (1984) Br J Clin Pharmacol , vol.17 , pp. 459-464
    • Grant, D.M.1    Tang, B.K.2    Kalow, W.3
  • 21
    • 0029989541 scopus 로고    scopus 로고
    • Genotyping of the polymorphic N-acetyltransferase (NAT2*) gene locus in two native African populations
    • Deloménie C, Sica L, Grant DM, Krishnamoorthy R, Dupret JM. Genotyping of the polymorphic N-acetyltransferase (NAT2*) gene locus in two native African populations. Pharmacogenetics 1996 ; 6 : 177-85.
    • (1996) Pharmacogenetics , vol.6 , pp. 177-185
    • Deloménie, C.1    Sica, L.2    Grant, D.M.3    Krishnamoorthy, R.4    Dupret, J.M.5
  • 22
    • 0000756778 scopus 로고
    • Detection of a new polymorphism of human arylamine N-acetyltransferase NAT1 using p-aminosalicylic acid as an in vivo probe
    • Grant DM, Vohra P, Avis Y, Ima A. Detection of a new polymorphism of human arylamine N-acetyltransferase NAT1 using p-aminosalicylic acid as an in vivo probe. J Basic Clin Physiol Pharmacol 1992 ; 3 (suppl) : 244.
    • (1992) J Basic Clin Physiol Pharmacol , vol.3 , Issue.SUPPL. , pp. 244
    • Grant, D.M.1    Vohra, P.2    Avis, Y.3    Ima, A.4
  • 25
    • 0026661470 scopus 로고
    • Metabolic activation of carcinogens
    • Guengerich FP. Metabolic activation of carcinogens. Pharmacol Ther 1992 ; 54 : 17-61.
    • (1992) Pharmacol Ther , vol.54 , pp. 17-61
    • Guengerich, F.P.1
  • 26
    • 0001360416 scopus 로고    scopus 로고
    • Genetic metabolic polymorphisms and the risk of cancer : A review of the literature
    • d'Errico A, Taioli E, Chen X, Vineis P. Genetic metabolic polymorphisms and the risk of cancer : a review of the literature. Biomarkers 1996 ; 1 : 149-73.
    • (1996) Biomarkers , vol.1 , pp. 149-173
    • D'Errico, A.1    Taioli, E.2    Chen, X.3    Vineis, P.4
  • 27
    • 0026695811 scopus 로고
    • Salmonella typhimurium strains expressing human arylamine N-acetyltransferases : Metabolism and mutagenic activation of aromatic amines
    • Grant DM, Josephy PD, Lord HL, Morrison LD. Salmonella typhimurium strains expressing human arylamine N-acetyltransferases : metabolism and mutagenic activation of aromatic amines. Cancer Res 1992 ; 52 : 3961-4.
    • (1992) Cancer Res , vol.52 , pp. 3961-3964
    • Grant, D.M.1    Josephy, P.D.2    Lord, H.L.3    Morrison, L.D.4
  • 28
    • 0027281895 scopus 로고
    • Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases
    • Hein DW, Doll MA, Rustan TD, Gray K, Feng Y, Ferguson RJ, Grant DM. Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases. Carcinogenesis 1993 ; 14 : 1633-8.
    • (1993) Carcinogenesis , vol.14 , pp. 1633-1638
    • Hein, D.W.1    Doll, M.A.2    Rustan, T.D.3    Gray, K.4    Feng, Y.5    Ferguson, R.J.6    Grant, D.M.7
  • 29
    • 0026701773 scopus 로고
    • The role of the human acetylation polymorphism in the metabolic activation of the food carcinogen 2-amino-3-methylimidazo(4,5-f) quinoline (IQ)
    • Probst MR, Blum M, Fasshauer I, D'Orazio D, Meyer UA, Wild D. The role of the human acetylation polymorphism in the metabolic activation of the food carcinogen 2-amino-3-methylimidazo(4,5-f) quinoline (IQ). Carcinogenesis 1992 ; 13 : 1713-7.
    • (1992) Carcinogenesis , vol.13 , pp. 1713-1717
    • Probst, M.R.1    Blum, M.2    Fasshauer, I.3    D'Orazio, D.4    Meyer, U.A.5    Wild, D.6
  • 30
    • 0029852566 scopus 로고    scopus 로고
    • New applications of bacterial systems to problems in toxicology
    • Guengerich FP, Gillam EMJ, Shimada T. New applications of bacterial systems to problems in toxicology. Crit Rev Toxicol 1996 ; 26 : 551-83.
    • (1996) Crit Rev Toxicol , vol.26 , pp. 551-583
    • Guengerich, F.P.1    Gillam, E.M.J.2    Shimada, T.3
  • 31
    • 0028040059 scopus 로고
    • Metabolic activation of aromatic and heterocyclic N-hydroxyarylamines by wild-type and mutant recombinant human NAT1 and NAT2 acetyltransferases
    • Hein DW, Rustan TD, Ferguson RJ, Doll MA, Gray K. Metabolic activation of aromatic and heterocyclic N-hydroxyarylamines by wild-type and mutant recombinant human NAT1 and NAT2 acetyltransferases. Arch Toxicol 1994 ; 68 : 129-33.
    • (1994) Arch Toxicol , vol.68 , pp. 129-133
    • Hein, D.W.1    Rustan, T.D.2    Ferguson, R.J.3    Doll, M.A.4    Gray, K.5
  • 32
    • 0028904406 scopus 로고
    • Acetylation of p-aminobenzoylglutamate, a folic acid catabolite, by recombinant human arylamine N-acetyltransferase and U937 cells
    • Minchin RF. Acetylation of p-aminobenzoylglutamate, a folic acid catabolite, by recombinant human arylamine N-acetyltransferase and U937 cells. Biochem J 1995 ; 307 : 1-3.
    • (1995) Biochem J , vol.307 , pp. 1-3
    • Minchin, R.F.1
  • 34
    • 0029815779 scopus 로고    scopus 로고
    • Combined analysis of inherited polymorphisms in arylamine N-acetyltransferase 2, glutathione S-transferases M1 and T1, microsomal epoxide hydrolase, and cytochrome P450 enzymes as modulators of bladder cancer risk
    • Brockmöller J, Cascorbi I, Kerb R, Roots, I. Combined analysis of inherited polymorphisms in arylamine N-acetyltransferase 2, glutathione S-transferases M1 and T1, microsomal epoxide hydrolase, and cytochrome P450 enzymes as modulators of bladder cancer risk. Cancer Res 1996 ; 56 : 3915-25.
    • (1996) Cancer Res , vol.56 , pp. 3915-3925
    • Brockmöller, J.1    Cascorbi, I.2    Kerb, R.3    Roots, I.4
  • 36
    • 0029032229 scopus 로고    scopus 로고
    • Inherited GSTM1 and NAT2 defects as concurrent risk modifiers in asbestos-related human malignant mesothelioma
    • Hirvonen A, Pelin K, Tammilehto L, Karjalainen A, Mattson K, Linnainmaa K. Inherited GSTM1 and NAT2 defects as concurrent risk modifiers in asbestos-related human malignant mesothelioma. Cancer Res 1996 ; 95 : 2981-3.
    • (1996) Cancer Res , vol.95 , pp. 2981-2983
    • Hirvonen, A.1    Pelin, K.2    Tammilehto, L.3    Karjalainen, A.4    Mattson, K.5    Linnainmaa, K.6
  • 40
    • 0029837310 scopus 로고    scopus 로고
    • Homozygous rapid arylamine N-acetyltransferase (NAT2) genotype as a susceptibility factor for lung cancer
    • Cascorbi I, Brockmöller J, Mrozikiewicz PM, Bauer S, Loddenkemper R, Roots I. Homozygous rapid arylamine N-acetyltransferase (NAT2) genotype as a susceptibility factor for lung cancer. Cancer Res 1996 ; 56 : 3961-6.
    • (1996) Cancer Res , vol.56 , pp. 3961-3966
    • Cascorbi, I.1    Brockmöller, J.2    Mrozikiewicz, P.M.3    Bauer, S.4    Loddenkemper, R.5    Roots, I.6
  • 41
    • 0027476961 scopus 로고
    • Molecular genetics of the N-acetyltransferases
    • Grant DM. Molecular genetics of the N-acetyltransferases. Pharmacogenetics 1993 ; 3 : 45-50.
    • (1993) Pharmacogenetics , vol.3 , pp. 45-50
    • Grant, D.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.