Effect of reduced Low-Density Lipoprotein receptor level on HepG2 cell cholesterol metabolism

Biochemical Journal

Volumn 329, Issue 1, 1998, Pages 81-89

  Izem, Lahoucine ^a   Rassart, Eric ^a   Kamate, Lassana ^a   Falstrault, Louise ^a   Rhainds, David ^a   Brissette, Louise ^a  

^a UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B; CHOLESTEROL; CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ESTER; COMPLEMENTARY DNA; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR;

ARTICLE; CELL STRAIN HEPG2; CHOLESTEROL METABOLISM; EXPRESSION VECTOR; HOMEOSTASIS; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PRIORITY JOURNAL;

APOLIPOPROTEINS B; CARCINOMA, HEPATOCELLULAR; CHOLESTEROL; CHOLESTEROL ESTERS; CULTURE MEDIA; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; IMMUNOBLOTTING; LIPOPROTEINS, LDL; PROTEIN BINDING; RECEPTORS, LDL; RNA, ANTISENSE; STEROL O-ACYLTRANSFERASE; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0031983253     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3290081     Document Type: Article

References (49)

1. Yamamoto, T., Davis, C. G., Brown, M. S., Schneider, W. J., Casey, M. L. and Goldstein, J. L. (1984) Cell 39, 27-38
2. Brown, M. S. and Goldstein, J. L. (1974) J. Biol. Chem. 249, 7305-7314
3. Saucier, S. E., Kandutsch, A. A., Gayen, A. K., Swahn, D. K. and Spencer, T. A. (1989) J. Biol. Chem. 264, 6863-6869
4. Goidstein, J. L. Dana, S. E. and Brown, M. S. (1974) Proc. Natl. Acad. Sci. U.S.A. 71, 4288-4292
5. Brown, M. S. and Goldstein, J. L. (1986) Science 232, 34-47.
6. Bilheimer, D. W., Watanabe, Y. and Kita, T. (1982) Proc. Natl. Acad. Sci. U.S.A. 79, 3305-3309
7. Havel, R. J. and Hamilton, R. L. (1988) Hepatology 8, 1689-1704
8. Dietschy, J. M., Turley, S. D. and Spady, D. K. (1993) J. Lipid Res. 34, 1637-1659
9. Miller, N. E., Weinstein, D. B. and Steinberg, O. (1978) J. Lipid Res. 19, 644-653
10. Bihain, B. E. and Yen, F. T. (1992) Biochemistry 31, 4628-4642
11. Brissette, L. and Noel, S. P. (1986) J. Biol. Chem. 261, 6847-6852
12. Brissette, L. and Falstrault, L. (1992) Biochim. Biophys. Acta 1165, 84-92
13. Brissette, L., Charest, M. C. and Falstrault, L. (1996) Biochem. J. 318, 841-847
14. Goldstein, J. L., Basu, S. K., Brunschede, G. Y. and Brown, M. S. (1979) Cell 7, 85-95
15. Havekes, L. M., De Wit, E. C. M. and Princen, H. M. G. (1987) Biochem J. 247, 739-746
16. Tam, S. P., Brissette, L., Ramarack, R. and Deeley, R. G. (1991) J. Biol. Chem. 266, 16764-16773
17. Izant, J. G. and Weintraub, H. (1984) Cell 36, 1007-1015
18. Izant, J. G. and Weintraub, H. (1985) Science 229, 345-351
19. McGarry, T. J. and Lindquist, S. (1986) Proc. Natl. Acad. Sci. U.S.A. 83, 399-403
20. Leblond, L. and Marcel, Y. M. (1991) J. Biol. Chem. 266, 6058-6067
21. Sambrook, J., Fritsch, E. F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd edn., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
22. Yoshimura, A., Yoshida, T., Seguch, T., Waki, M., Ono, M. and Kuwano, M. (1987) J. Biol. Chem. 262, 13299-13308
23. Laemmli, U. K. (1970) Nature (London) 227, 680-685
24. Burnette, W. N. (1981) Anal. Biochem. 112, 195-203
25. Beiseigel, U., Schneider, W. J., Goldstein, J. L., Anderson, R. G. W. and Brown, M. S. (1981) J. Biol. Chem. 256, 11923-11931
26. Hatch, F. T. and Lees, R. S. (1968) Adv. Lipid Res. 6, 1-68
27. Langer, T., Strober, W. and Levy, R. I. (1972) J. Clin. Invest. 51, 1528-1536
28. McFarlane, A. S. (1948) Nature (London) 182, 53-54
29. Roberts, D. C. K., Miller, N. E., Price, S. G. L., Crook, D., Cortese, C., LaVille, A., Masana, L. and Lewis, I. (1985) Biochem. J. 226, 319-322
30. Scatchard, G. (1949) Ann. N.Y. Acad. Sci. 51, 660-672
31. Rosentnal, H. B. (1967) Anal. Biochem. 20, 525-532.
32. Brown, M. S., Dana, S. E. and Goldstein, J. L. (1974) J. Biol. Chem. 249, 789-796
33. Evans, A. J., Sawyez, C. G., Wolfe, B. M. and Huff, M. (1992) J. Biol. Chem. 267, 10743-10751
34. Goldslein, J. L., Basu, S. K. and Brown, M. S. (1983) Methods Enzymol. 98, 241-260
35. Lowry, O. H., Rosebrough, N. J., Farr, A. L. and Randall, R. J. (1951) J. Biol. Chem. 193, 265-275
36. Ishibashi, S., Brown, M. S., Goldstein, J. L., Gerard, R. D., Hammer, R. E. and Herz, J. L. (1993) J. Clin. Invest. 92, 883-593
37. Guzelian, P. S., Li, D., Schuetz, E. G., Thomas, P., Levin, W., Mode, A. and Gustafsson, J.-A. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 9783-9787
38. Hayshi, K., Nakashima, K., Saeki, M., Kurushima, H., Kurokawa, J.-I., Kuga, Y., et al. (1993) Atherosclerosis 104, 105-115
39. Chen, Q., Floren, C. H., Nilsson, A. and Infante, R. (1991) Biochim. Biophys. Acta 1083, 173-178
40. Myant, N. B. (1983) Klin. Wochenschr. 34, 383-401
41. Medicherla, S., Azhar, S., Cooper, A. and Reaven, E. (1996) Biochemistry 35, 6243-6250
42. Rinninger, F., Jaeckle, S., Greten, H. and Windler, E. (1993) Biochim. Biophys. Acta 1166, 284-299
43. Green, S. R. and Pittman, R. C. (1991) J. Lipid Res. 32, 667-678
44. Fielding, C. J. and Fielding, P. (1995) Biochemistry 34, 14237-14244
45. Folz, R. J. and Gordon, J. I. (1986) J. Biol. Chem. 261, 14752-14759
46. Havekes, L. M., Schouten, D., De Wit, E. C. M., Cohen, L. H., Griffioen, M., Van Hinsbergh, V. W. and Princen, H. M. G. (1986) Biochim. Biophys. Acta 875, 236-246
47. Gibbons, G. F., Khurana, A., Odwell, A. and Seelaender, M. C. L. (1994) J. Lipid Res. 35, 1801-1808
48. Everson, G. T. and Polokoff, M. A. (1986) J. Biol. Chem. 261, 2197-2201
49. Farrants, A.-K. O., Nilsson, A. and Pedersen, J. I. (1993) J. Lipid Res. 34, 2041-2050