Changes to the cytokine microenvironment in the genital tract mucosa of HIV+ women

Clinical and Experimental Immunology

Volumn 112, Issue 1, 1998, Pages 100-104

  Olaitan, A ^a   Johnson, M A ^a   Reid, W M ^a   Poulter, L W ^a  

^a ROYAL FREE HOSPITAL   (United Kingdom)

Author keywords

Cytokines; Female; HIV; Immunology; Uterine cervix

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; MESSENGER RNA;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GENITAL TRACT INFECTION; HELPER CELL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; LYMPHOCYTE COUNT; OPTICAL DENSITY; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; UTERINE CERVIX BIOPSY; UTERINE CERVIX CARCINOMA IN SITU; UTERINE CERVIX MUCOSA;

ADULT; CYTOKINES; FEMALE; GENITALIA, FEMALE; HIV INFECTIONS; HIV-1; HUMANS; IMMUNITY, MUCOSAL; IN SITU HYBRIDIZATION; MIDDLE AGED; RNA, MESSENGER; T-LYMPHOCYTES;

EID: 0031981298     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1998.00561.x     Document Type: Article

References (28)

1. Rebello R, Green FH. A study of the secretory system of the female genital tract. Br J Obstet Gynaecol 1975; 82:812-6.
2. Morris HHB, Gatter KC, Stein H, Mason DY. Langerhans cells in human cervical epithelium: an immunohistochemical study. Br J Obstet Gynaecol 1983; 90:400-11.
3. Kutteh WH, Hatch KD, Blackwell RE, Metescy J. Secretory immune system of the female reproductive tract: 1. Immunoglobulin and secretory component-containing cells. Obstet Gynecol 1988; 71:56-60.
4. Nicoll A, Hutchinson E, Soldan K et al. Survey of human immunodeficiency virus infection among pregnant women in England and Wales: 1990-93. Communicable Dis Report 1994; 4:R115-R120.
5. Chin J. Current and future dimensions of the HIV/AIDS pandemic in women and children. Lancet 1990; 3336:221-4.
6. European Study Group on Heterosexual Transmission of HIV. Comparison of female to male and male to female transmission of HIV in 563 stable couples. Br Med J 1992; 304:809-13.
7. European Collaborative Study. Risk factors for mother-to-child transmission of HIV-1. Lancet 1992; 339:1007-12.
8. European Collaborative Study. Caesarean section and the risk of vertical transmission of HIV infection. Lancet 1994; 343:1464-7.
9. Olaitan A, Johnson MA, Maclean AB, Poulter LW. The distribution of immunocompetent cells in the genital tract mucosa of HIV-positive women. AIDS 1996; 10:759-64.
10. Lai PK, Tamura Y, Bradley WG, Donovan J, Tanaka A, Nonoyama M. Cytokine regulation of the human immunodeficiency virus. Int J Immunopharmacol 1991; 13 (Suppl. 1):55-61.
11. Poli G, Fauci AS. The effect of cytokines and pharmacological agents on chronic HIV infection. AIDS Res Human Retrovir 1992; 8:191-7.
12. Belec L, Gherardi R, Payan C, Prazuck T, Malkin JE, Tevi-Benissan C, Pillot J. HIV-enhancing pro-inflammatory cytokines in cervico-vaginal secretions of normal and HIV-infected women. Cytokine 1995; 7:568-74.
13. Mossman TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T cell clone. Definitions according to profiles of cytokine activities, and secreted proteins. J Immunol 1986; 136:2348-57.
14. Sander B, Skansen-Saphir U, Damm O, Hakansson L, Andersson J, Andersson U. Sequential production of Th1 and Th2 cytokines in response to live bacillus Calmette-Guerin. Immunol 1995; 82:512-8.
15. Ichinose H, Miyazaki M, Koji T et al. Detection of cytokine mRNA-expressing cells in peripheral blood of patients with IgA nephropathy using non-radioactive in situ hybridisation. Clin Exp Immunol 1996; 103:125-32.
16. Mossman TR, Moore KW. The role of IL-10 in cross regulation of Th-1 and Th-2 responses. Immunol Today 1991; 12:A48-A53.
17. Clerici M, Sarin A, Coffman RL et al. Type 1/type 2 cytokine modulation of T-cell programmed cell death as a model for human immunodeficiency virus pathogenesis. Proc Natl Acad Sci USA 1994; 91:11811-5.
18. Del Prete G, Maggi E, Pizzolo G, Romagnani S. CD30, Th-2 cytokines and HIV infection: a complex and fascinating link. Immunol Today 1995; 16:76-80.
19. McGowan I, Radford-Smith G, Jewell DP. Cytokine gene expression in HIV-infected intestinal mucosa. AIDS 1994; 8:1569-75.
20. Clerici M, Shearer GM. A Th-1 to Th-2 switch is a critical step in the etiology of HIV infection. Immunol Today 1993; 17:256-8.
21. Wofsy CB, Cohen JB, Hauer LB, Pandian NS, Michaelis BA, Evans LA, Levy JA. Isolation of AIDS-associated retrovirus from genital tract secretions of women with antibodies to the virus. Lancet 1986; 527-9.
22. Voght MW, Witt DJ, Craven DE, Byington Y, Crawford DF, Schooley RT, Hirsch MS. Isolation of HTLVIII/LAV from cervical secretions of women at risk of AIDS. Lancet 1986; 525-7.
23. Clemetson BD, Moss GB, Willerford DM et al. Detection of HIV DNA in cervical and vaginal secretions. Prevalence and correlates among women in Nairobi, Kenya. JAMA 1993; 269:2860-4.
24. + cell clones secrete Th-1 pattern of cytokines. J Immunol 1990; 144:1744-52.
25. + activity in vivo. J Immunol 1993; 151:48-90.
26. Clerici M, Merola M, Ferrario E et al. Cytokine production patterns in cervical intraepithelial neoplasia: association with human papillomavirus infection. J Natl Cancer Inst 1997; 89:245-50.
27. Agarossi A, Muggiasca M, Ravasi L et al. HIV infection and CIN. VIII international conference on AIDS, Milan. Abstract book no. 3045, 1992:B95.
28. Van Doornum GJ, Van den Hoek JA, Van Ameijden EJ, Van Haastrecht HJ, Roos MT, Henquet CJ, Quint WG, Coutinho RA. Cervical HPV infection among HIV-infected prostitutes addicted to hard drugs. J Med Virol 1993; 41:185-90.