Accelerated structure profiling using automated LC-MS and Robotics

Pharmaceutical Technology

Volumn 22, Issue 5, 1998, Pages 76-82

  Whitney, Jeffrey L ^a   Kerns, Edward H ^b   Rourick, Robyn A ^a   Hail, Mark E ^b   Volk, Kevin J ^b   Fink, Saul W ^b   Lee, Mike S ^b  

^a BRISTOL MYERS SQUIBB   (United States)

^b BRISTOL MYERS SQUIBB PHARMACEUTICAL RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AUTOANALYZER; AUTOMATION; DATA BASE; DRUG MANUFACTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFORMATION PROCESSING; MASS SPECTROMETRY;

EID: 0031980942     PISSN: 01478087     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. E.H. Kerns et al., "Recent Applications of Accelerated Structure Analysis Protocols," in Proceedings of ISLAR (International Symposium on Laboratory Automation and Robotics, 1996), p. 324.
2. M.S. Lee and R.A. Yost, "Rapid Identification of Drug Metabolites with Tandem Mass Spectrometry," Biomed. Env. Mass. Spectrom. 15, 193 (1998).
3. E.H. Kerns et al., "Profiling Taxanes in Taxus Extracts Using LC-MS and LC-MS-MS Techniques," J. Nat. Prod. 57 (10), 1391-1403 (1994).
4. E.H. Kerns et al., "Profiling New Taxanes Using LC-MS and LC-MS-MS Substructural Analysis Techniques," Rapid Comm. Mass. Spectrom. 9, 1539-1545 (1995).
5. R.A. Rourick et al., "LC-MS Strategy for the Rapid Profiling of Solid Phase Synthetic Products," in Proceedings of the 43rd ASMS Conference on Mass Spectrometry Allied Topics (American Society for Mass Spectrometry, 1995), p. 489.
6. M.S. Lee et al., "Rapid Screening of Fermentation Broths for Flavones Using Tandem Mass Spectrometry," Biol. Mass. Spectrom. 22, 84 (1993).
7. J.L. Whitney et al., "Accelerated Structure Profiling Using Automated LC/MS and Robotics," in Proceedings of ISLAR (International Symposium on Laboratory Automation and Robotics, 1997), p. 323.