메뉴 건너뛰기




Volumn 76, Issue 4, 1998, Pages 435-439

Different chronotropic and inotropic effects of EMD 57033 and EMD 53998, Ca2+ sensitizers, on isolated, blood-perfused dog heart preparations

Author keywords

Ca2+ sensitizer; EMD 57033; Sinus rate

Indexed keywords

5 [1 (3,4 DIMETHOXYBENZOYL) 1,2,3,4 TETRAHYDRO 6 QUINOLYL] 3,6 DIHYDRO 6 METHYL 2H 1,3,4 THIADIAZIN 2 ONE; CALCIUM ION; PROPRANOLOL;

EID: 0031980813     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.76.435     Document Type: Article
Times cited : (1)

References (13)
  • 1
    • 0027315063 scopus 로고
    • Basic pharmacology and clinical application of new positive inotropic agents
    • Endoh M and Hori M: Basic pharmacology and clinical application of new positive inotropic agents. Drugs Today 29, 29-56 (1993)
    • (1993) Drugs Today , vol.29 , pp. 29-56
    • Endoh, M.1    Hori, M.2
  • 2
    • 0026466472 scopus 로고
    • Cyclic-AMP-dependent positive chrono- and inotropic responses in the blood-perfused dog atrium
    • Chiba S, Karasawa Y and Furukawa Y: Cyclic-AMP-dependent positive chrono- and inotropic responses in the blood-perfused dog atrium. Adv Second Messenger Phosphoprotein Res 25, 363-372 (1992)
    • (1992) Adv Second Messenger Phosphoprotein Res , vol.25 , pp. 363-372
    • Chiba, S.1    Karasawa, Y.2    Furukawa, Y.3
  • 3
    • 0023502557 scopus 로고
    • 2+ sensitivity of the contractile system by MCI-154, a novel cardiotonic agent in chemically skinned fibers from the guinea pig papillary muscles
    • 2+ sensitivity of the contractile system by MCI-154, a novel cardiotonic agent in chemically skinned fibers from the guinea pig papillary muscles. J Pharmacol Exp Ther 243, 633-638 (1987)
    • (1987) J Pharmacol Exp Ther , vol.243 , pp. 633-638
    • Kitada, Y.1    Narimatsu, A.2    Matsumura, N.3    Endo, M.4
  • 4
    • 0027493823 scopus 로고
    • Positive chronotropic and inotropic responses to novel cardiotonics, NKH 477 and MCI-154 in isolated, perfused canine heart preparations
    • Sawaki S, Furukawa Y, Inoue Y, Takayama S and Chiba S: Positive chronotropic and inotropic responses to novel cardiotonics, NKH 477 and MCI-154 in isolated, perfused canine heart preparations. Asia Pac J Pharmacol 8, 133-140 (1993)
    • (1993) Asia Pac J Pharmacol , vol.8 , pp. 133-140
    • Sawaki, S.1    Furukawa, Y.2    Inoue, Y.3    Takayama, S.4    Chiba, S.5
  • 5
    • 0027276723 scopus 로고
    • The two mechanisms of action of racemic cardiotonic EMD 53998, calcium sensitization and phosphodiesterase inhibition, reside in different enantiomers
    • Lues I, Beier N, Jonas R, Klockow M and Haeusler G: The two mechanisms of action of racemic cardiotonic EMD 53998, calcium sensitization and phosphodiesterase inhibition, reside in different enantiomers. J Cardiovasc Pharmacol 21, 883-892 (1993)
    • (1993) J Cardiovasc Pharmacol , vol.21 , pp. 883-892
    • Lues, I.1    Beier, N.2    Jonas, R.3    Klockow, M.4    Haeusler, G.5
  • 7
    • 0027513094 scopus 로고
    • Enantiomeric dissection of the effects of the inotropic agent, EMD 53998, in single cardiac myocytes
    • Gambassi G, Capogrossi MC, Klockow M and Lakatta EG: Enantiomeric dissection of the effects of the inotropic agent, EMD 53998, in single cardiac myocytes. Am J Physiol 264, H728-H738 (1993)
    • (1993) Am J Physiol , vol.264
    • Gambassi, G.1    Capogrossi, M.C.2    Klockow, M.3    Lakatta, E.G.4
  • 9
    • 34250400666 scopus 로고
    • Muscarinic suppression of the nicotinic action of acetylcholine on the isolated, blood-perfused atrium of the dog
    • Chiba S, Kimura T and Hashimoto K: Muscarinic suppression of the nicotinic action of acetylcholine on the isolated, blood-perfused atrium of the dog. Naunyn Schmiedebergs Arch Pharmacol 289, 315-325 (1975)
    • (1975) Naunyn Schmiedebergs Arch Pharmacol , vol.289 , pp. 315-325
    • Chiba, S.1    Kimura, T.2    Hashimoto, K.3
  • 10
    • 0017177222 scopus 로고
    • Effects of pentobarbital, verapamil and manganese on the frequency-force relationship of the isolated atrium and ventricle of the dog heart
    • Chiba S: Effects of pentobarbital, verapamil and manganese on the frequency-force relationship of the isolated atrium and ventricle of the dog heart. Eur J Pharmacol 40, 225-232 (1976)
    • (1976) Eur J Pharmacol , vol.40 , pp. 225-232
    • Chiba, S.1
  • 12
    • 0026048386 scopus 로고
    • EMD 53998 sensitizes the contractile proteins to calcium in intact ferret ventricular muscle
    • Lee JA and Allen DG: EMD 53998 sensitizes the contractile proteins to calcium in intact ferret ventricular muscle. Circ Res 69, 927-936 (1991)
    • (1991) Circ Res , vol.69 , pp. 927-936
    • Lee, J.A.1    Allen, D.G.2
  • 13
    • 0028786495 scopus 로고
    • Effects of EMD 57033 on contraction and relaxation in isolated rabbit hearts
    • Hgashiyama A, Watkins MW, Chen Z and Lewinter MM: Effects of EMD 57033 on contraction and relaxation in isolated rabbit hearts. Circulation 92, 3094-3104 (1995)
    • (1995) Circulation , vol.92 , pp. 3094-3104
    • Hgashiyama, A.1    Watkins, M.W.2    Chen, Z.3    Lewinter, M.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.