Pretreatment with isradipine, a calcium-channel blocker, does not attenuate the acute behavioral effects of ethanol in humans

Alcoholism: Clinical and Experimental Research

Volumn 22, Issue 2, 1998, Pages 539-547

  Rush, Craig R ^a   Pazzaglia, Peggy J ^a  

^a UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

Alcohol; Calcium channel blockers; Ethanol; Humans; Isradipine

Indexed keywords

ALCOHOL; CALCIUM CHANNEL BLOCKING AGENT; ISRADIPINE;

ADULT; ALCOHOL CONSUMPTION; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; DOSE RESPONSE; DRUG ALCOHOL INTERACTION; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

EID: 0031980793     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1998.tb03686.x     Document Type: Article

References (40)

1. SAMHSA: Preliminary Estimates from the 1995 National Household Survey on Drug Abuse. Rockville, MD, U.S. Department of Health and Human Services, USDHHS Publication No. (SMA) 96-3107, 1996
2. National Institute on Alcohol Abuse and Alcoholism: Seventh Special Report to the U.S. Congress on Alcohol and Health. Rockville, MD, U.S. Department of Health and Human Services, USDHHS Publication No. (ADM) 90-1656, 1990
3. Colombo G, Agabio R, Lobina C, Reali R, Fadda F, Gessa GL: Blockade of ethanol discrimination by isradipine. Eur J Pharmacol 265:167-170, 1994
4. Colombo G, Agabio R, Lobina C, Reali R, Melis F, Fadda F, Gessa GL: Effects of calcium channel antagonist dapodipine on ethanol withdrawal in rats. Alcohol Alcohol 30:125-131, 1995
5. Czarnecka E, Kubik-Bogucka E: Effects of calcium antagonists on central actions of ethanol: Comparative studies with nifedipine, verapamil and cinnarizine. Alcohol Alcohol 28:649-655, 1993
6. Engel JA, Fahlke C, Multhe P, Hard E, Johannessen K, Snape B, Svensson L: Biochemical and behavioral evidence for an interaction between ethanol and calcium channel antagonists. J Neural Transm 74:181-193, 1988
7. Fadda F, Garau B, Colombo G, Gessa GL: Isradipine and other calcium channel antagonists attenuate ethanol consumption in ethanol-preferring rats. Alcohol Clin Exp Res 16:449-452, 1992
8. Pucilowski O, Krzascik P, Trzaskowska E, Kostowski W: Different effect of diltiazem and nifedipine on some central actions of ethanol. Alcohol 6:165-168, 1989
9. Rezvani AH, Grady DR, Janowsky DS: Effect of calcium-channel blockers on alcohol consumption in alcohol-drinking monkeys. Alcohol Alcohol 26:161-167, 1992
10. White JM, Smith AM: Modification of the behavioral effects of ethanol by nifedipine. Alcohol Alcohol 27:137-141, 1992
11. Bauer LA, Schumock G, Horn J, Opheim K: Verapamil inhibits ethanol elimination and prolongs its perception of intoxication. Clin Pharmacol Ther 52:6-10, 1992
12. Perez-Reyes M, White WR, Hicks RE: Interaction between ethanol and calcium channel blockers in humans. Alcohol Clin Exp Res 16:769-775, 1992
13. Zacny JP, Yajnih S: Effects of calcium channel inhibitors on ethanol effects and pharmacokinetics in healthy volunteers. Alcohol 10:505-509, 1993
14. Higgins ST, Rush CR, Hughes JR, Bickel WK, Lynn M, Capeless MA: Acute behavioral and cardiac effects of cocaine and alcohol combinations in humans. Psychopharmacology 111:285-294, 1993
15. Rush CR, Higgins ST, Hughes JR, Bickel WK, Wiegner MS: Acute behavioral and cardiac effects of alcohol and caffeine, alone and in combination, in humans. Behav Pharmacol 4:562-572, 1993
16. Rush CR, Griffiths RR: Acute subject-rated and behavioral effects of alprazolam and buspirone, alone and in combination with ethanol, in normal volunteers. Exp Clin Psychopharmacol 5:28-38, 1996
17. Jasinski DR: Assessment of the abuse potentiality of morphine-like drugs (methods used in man), in Martin WR (ed): Drug Addiction, vol I. New York, Springer-Verlag, 1977, pp 197-258
18. Martin WR, Sloan JW, Sapiro JD, Jasinski DR: Physiologic, subjective, and behavioral effects of amphetamine, methamphetamine, ephedrine, phenmetrazine, and methylphenidate in man. Clin Pharmacol Ther 12:245-258, 1971
19. Maisto SA, Connors GJ, Tucker JA, McCollam JB: Validation of the sensation scale, a measure of subjective physiological responses to alcohol. Behav Res Ther 18:37-43, 1980
20. Griffiths RR, Rush CR, Puhala KA: Validation of the multiple-choice procedure for investigating drug reinforcement in humans. Exp Clin Psychopharmacol 4:97-106, 1996
21. Griffiths RR, Troisi JR II, Silverman K, Mumford GK: Multiple-choice procedure: An efficient approach for investigating drug reinforcement in humans. Behav Pharmacol 4:3-13, 1993
22. McLeod DR, Griffiths RR, Bigelow GE, Yingling JE: An automated version of the digit symbol substitution test (DSST). Behav Res Methods Instr 14:463-466, 1982
23. Clifton GD, Blouin RA, Dilea C, Schran HF, Hassell AE, Gonasun LM, Foster TS: The pharmacokinetics of oral isradipine in normal volunteers. J Clin Pharmacol 28:36-42, 1988
24. Tse FSL, Jaffe JM: Pharmacokinetics of PN 200-110 (isradipine), a new calcium channel antagonist, after oral administration in man. Eur J Clin Pharmacol 32:361-365, 1987
25. Higgins ST, Roll JM, Bickel WK: Alcohol pretreatment increases preference for cocaine over monetary reinforcement. Psychopharmacology 123:1-8, 1996
26. Preston KL, Bigelow GE: Subjective and discriminative effects of drugs. Behav Pharmacol 2:293-313, 1991
27. Schuster CR, Johanson CE: Relationship between the discriminative stimulus properties and subjective effects of drugs, in Colpaert FC, Balster RL (eds): Transduction Mechanisms of Drug Stimuli, Berlin, Springer-Verlag, 1988, pp 161-175
28. Schuster CR, Fischman MW, Johanson CE: Internal stimulus control and subjective effects of drugs, in Thompson T, Johanson, CE (eds): Behavioral Pharmacology of Human Drug Dependence. Rockville, MD, NIDA Research Monograph No. 92, U.S. Department of Health and Human Services, Public Health Service, Alcohol, Drug Abuse and Mental Health, National Institute on Drug Abuse, 1981, pp 116-129
29. Woolverton WL, Schuster CR: Behavioral and pharmacological aspects of opioid of dependence: Mixed agonist-antagonists. Pharmacol Rev 35:33-52, 1983
30. Schechter MD: Discriminative stimulus properties of isradipine: Effect of other calcium channel blockers. Pharmacol Biochem Behav 50:539-543, 1995
31. Brogden RN, Sorkin EM: Isradipine: An update of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the treatment of mild to moderate hypertension. Drugs 49:618-639, 1995
32. Fitton A, Benfield P: Isradipine: A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in cardiovascular disease. Drugs 40:31-74, 1990
33. Griffiths RR, Balster RL: Opioids: Similarity between evaluations of subjective effects and animal self-administration results. Clin Pharmacol Ther 25:611-617, 1979
34. Lamb RJ, Preston KL, Schindler CW, Meisch RA, Davis F, Katz JL, Henningfield JE, Goldberg SR: The reinforcing and subjective effects of morphine in post-addicts: A dose-response study. J Pharmacol Exp Ther 25:1165-1173, 1991
35. Rush CR, Critchfield TS, Troisi JR II, Griffiths RR: Discriminative stimulus effects of diazepam and buspirone in normal volunteers. J Exp Anal Behav 63:277-294, 1995
36. Kamien JB: Studying Ethanol Pharmacology Using Human Drug Discrimination Procedures. Presentation at the annual meeting of the College on Problems of Drug Dependence, Nashville, TN, 1997
37. Spiga R, Meisch RA, Roache JD, Grabowski J, Johnson B: Human ethanol self-administration. II. Effects of naltrexone on ethanol self-administration. Submitted for publication, 1997
38. Spiga R, Roache JD: Human drug self-administration: A review and methodological critique, in Johnson BA, Roache JD (eds): Drug Abuse and its Treatment: Nexus of Neuroscience and Behavior. Philadelphia, Lippincott-Raven Publishers, 1997, pp 39-71
39. Fischman MW, Mello NK: Testing for Abuse Liability of Drugs in Humans. National Institute on Drug Abuse Monograph No. 92, Department of Health and Human Services Publication No. (ADM)89-1613. Washington, D.C., U.S. Government Printing Office, 1989
40. Doty P, de Wit H: Effects of naltrexone pretreatment on the subjective and performance effects of ethanol in social drinkers. Behav Pharmacol 6:386-394, 1995